SLC5A10 cDNA ORF clone, Sus scrofa(pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC5A10
Entrez Gene ID	497235
Full Name	solute carrier family 5 member 10
Synonyms	SGLT1,SGLT5,SLC5A1
Gene Type	protein-coding
Organism	Sus scrofa(pig)
Genome	Chromosome: 12 Map Location: 12\|12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012297.1	NP_001012297.1	sodium/glucose cotransporter 5

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Effect of heat stress on performance and expression of selected amino acid and glucose transporters, HSP90, leptin and ghrelin in growing pigs.
Cervantes M, Cota M, Arce N, Castillo G, Avelar E, Espinoza S, Morales A
Journal of thermal biology5969-76(2016 Jul)

Transmissible Gastroenteritis Virus Infection Enhances SGLT1 and GLUT2 Expression to Increase Glucose Uptake.
Dai L, Hu WW, Xia L, Xia M, Yang Q
PloS one11(11)e0165585(2016)

Segmental diversity of electrogenic glucose transport characteristics in the small intestines of weaned pigs.
Herrmann J, Schr?der B, Klinger S, Thorenz A, Werner AC, Abel H, Breves G
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology163(1)161-9(2012 Sep)

Histomorphology and small intestinal sodium-dependent glucose transporter 1 gene expression in piglets fed phytic acid and phytase-supplemented diets.
Woyengo TA, Rodriguez-Lecompte JC, Adeola O, Nyachoti CM
Journal of animal science89(8)2485-90(2011 Aug)

Apical Na+-D-glucose cotransporter 1 (SGLT1) activity and protein abundance are expressed along the jejunal crypt-villus axis in the neonatal pig.
Yang C, Albin DM, Wang Z, Stoll B, Lackeyram D, Swanson KC, Yin Y, Tappenden KA, Mine Y, Yada RY, Burrin DG, Fan MZ
American journal of physiology. Gastrointestinal and liver physiology300(1)G60-70(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Feed intake remains low whereas respiratory frequency and body temperature remain higher and expression of HSP90, CAT1, SGLT1 and GLUT4 increases in some tissues in pigs under chronic heat stress conditions.
Title: Effect of heat stress on performance and expression of selected amino acid and glucose transporters, HSP90, leptin and ghrelin in growing pigs.

the effects of Transmissible gastroenteritis virus infection on glucose uptake and SGLT1 and GLUT2 expression, are reported.
Title: Transmissible Gastroenteritis Virus Infection Enhances SGLT1 and GLUT2 Expression to Increase Glucose Uptake.

The segmental differences in porcine glucose transport characteristics may be based on direct or indirect modulations of SGLT1 activity.
Title: Segmental diversity of electrogenic glucose transport characteristics in the small intestines of weaned pigs.

The increased expression of SGLT1 in the jejunum by phytase supplementation implies that phytase alleviated the negative effects of phytic acid partly through increased expression of SGLT1.
Title: Histomorphology and small intestinal sodium-dependent glucose transporter 1 gene expression in piglets fed phytic acid and phytase-supplemented diets.

neonates have high intestinal apical SGLT1 uptake activity by abundantly expressing SGLT1 protein in epithelia and on apical membrane along the entire crypt-villus axis in association with enhanced protein translational control mechanisms in crypt cells.
Title: Apical Na+-D-glucose cotransporter 1 (SGLT1) activity and protein abundance are expressed along the jejunal crypt-villus axis in the neonatal pig.

The following SLC5A10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC5A10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSe00265	NM_001012297.1 Latest version!	Sus scrofa solute carrier family 5 member 10 (SLC5A10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC5A10 ( NM_001012297.1 ) cDNA ORF clone, Sus scrofa(pig) -> NP_001012297.1 Sus scrofa solute carrier family 5 member 10 (SLC5A10), mRNA.

Price & Availability↑

CloneID	OSe00265
Clone ID Related Accession (Same CDS sequence)	NM_001012297.1
Accession Version	NM_001012297.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Sus scrofa(pig)
Product	sodium/glucose cotransporter 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY876919.1. ##Evidence-Data-START## Transcript exon combination :: AY876919.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1964466, SAMEA2040583 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCCG ACAACTCCTC CAGCGACCCC CACGCTCCCG GGCCGCAGCT CAGCGTGGCC 
GACGTCGTCA TCGTCGCTGT GTACTTCGCC GTGAACATGG CCGTGGGCGT ATGGTCTTCA 
TGCCGGGCCA GCAGGAACAC AGTGAGTGGC TACTTCCTGG CGGGCCGGGA CATGATGTGG 
CGGCCGATTG GAGCCTCCCT CTTTGCCAGC AGCGAGGGCT CGGGCCTCTT TGTCGGACTG 
GCGGGCTCGG GCGCGGCGGG CGGCCTGGCA GTGGCAGGCT TCGAGTGGCA TGCCACGTAC 
GTGCTGCTGG CCCTGGCCTG GGTGTTTGTG CCCATCTACA TCTCCTCGGA GATTGTCACC 
ATGCCGGAGT ACATCCAGAA GCGCTACGGC GGCCAGCGGA TACGCATGTA CCTGTCTGTC 
CTGTCGCTGC TGCTCTCCAT CTTCACCAAG ATATCGATTG ACCTGTACGC AGGGGCGCTG 
TTCGTGCACA TCTGTCTGGG CTGGAACTTC TACCTCTCCA CCTGCCTCAT GCTCGTCATC 
ACCGCCCTGT ACACCATCGC AGGGGGCCTG GCGGCTGTCA TCTACACCGA CGCCCTGCAG 
ACGCTCATCA TGGTGGTGGG GGCCGTGATC CTCACGGTCA AAGCTTTCCA GCAGATCGGC 
GGGTATGAGC AGCTGGCAGC TGCCTACGCC CAGGCCATCC CCTCCAAGAC CATCTCCAAC 
ACGACGTGCC ACCTGCCGCG GGCAGACGCC ATGCACATGT TCCGAGACCC CGCCACGGGG 
GACCTGCCGT GGACCGGCAT GACCTTCGGC CTGACCATCA TGGCCACCTG GTACTGGTGC 
ACCGACCAGG TCATCGTGCA GCGGTCGCTG TCGGCCCGGG ACCTGAACCA CGCCAAGGGG 
GGCTCCATCC TGGCCAGCTA CCTCAAGATG CTGCCCATGG GCCTGATGGT CATGCCGGGC 
ATGATCAGCC GCGTGCTGTT TCCAGATGAT GTGGGCTGCG TGGTGCCATC CGAGTGCCTG 
CGGGCCTGTG GGGCCGAGAT TGGCTGCTCC AACATCGCCT ACCCCAAGCT GGTCATGGAG 
CTGATGCCCA CAGGTCTGCG GGGGCTGATG GTCGCCGTGA TGATGGCCGC GCTCATGTCC 
TCGCTGACGT CCATCTTTAA CAGCAGCAGC ACCCTCTTCA CCATGGACGT CTGGAGGCGG 
CTGCGGCCCC GCGCCGGCGA GCGGGAGCTG CTGCTGGTGG GACGGCTGGT CATCGTCGTG 
CTCATTGGCG TGAGCGTGGC CTGGATCCCC GTCCTGCAAG GCTCCAACAG CGGGCAGCTC 
TTCATCTACA TGCAGTCGGT GACCAGCTCG CTGGCCCCCC CGGTGACCGC GGTCTTTGTC 
CTGGGCATCT TCTGGCGGCG GGCCAACGAG CAGGGGGCCT TCTGGGGCCT GATGGTGGGG 
CTGGCGGTGG GCGCCTGGAG GCTGGTCCTG GAGTTCCTGC ACCCCGCCCC GCCCTGCGGC 
CACCCCGACG TGCGGCCGGC CCTGCTCCGC ACGGTCCACT ACCTGCACTT CGCCGTGGCG 
CTCTTCGTCC TCAGCGGGGC CGTGGTGGCG GCCGTGAGCC TGCTGACGCC GCCCCCCGCG 
GGCGTCCAGA TCGAGAACCT CACGTGGTGG ACCCTGGCTC GGGACCGGCC CTCGGGGGCC 
AAAACAGGTG ACGGCCCAGC ATCCCAGAAA CACGCCTTCT GGGCCCGGGT CTGCAGCCTC 
AACGCCGTCC TCCTCGTGTG TGTCAACCTC TTCTTTTACG CCTACTTCGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012297.1
CDS	6..1799
Translation	MAADNSSSDPHAPGPQLSVADVVIVAVYFAVNMAVGVWSSCRASRNTVSGYFLAGRDMMWRPIGASLFASSEGSGLFVGLAGSGAAGGLAVAGFEWHATYVLLALAWVFVPIYISSEIVTMPEYIQKRYGGQRIRMYLSVLSLLLSIFTKISIDLYAGALFVHICLGWNFYLSTCLMLVITALYTIAGGLAAVIYTDALQTLIMVVGAVILTVKAFQQIGGYEQLAAAYAQAIPSKTISNTTCHLPRADAMHMFRDPATGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKGGSILASYLKMLPMGLMVMPGMISRVLFPDDVGCVVPSECLRACGAEIGCSNIAYPKLVMELMPTGLRGLMVAVMMAALMSSLTSIFNSSSTLFTMDVWRRLRPRAGERELLLVGRLVIVVLIGVSVAWIPVLQGSNSGQLFIYMQSVTSSLAPPVTAVFVLGIFWRRANEQGAFWGLMVGLAVGAWRLVLEFLHPAPPCGHPDVRPALLRTVHYLHFAVALFVLSGAVVAAVSLLTPPPAGVQIENLTWWTLARDRPSGAKTGDGPASQKHAFWARVCSLNAVLLVCVNLFFYAYFA

Target ORF information:

RefSeq Version	NM_001012297.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa solute carrier family 5 member 10 (SLC5A10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012297.1

ORF Insert Sequence:

ATGGCGGCCG ACAACTCCTC CAGCGACCCC CACGCTCCCG GGCCGCAGCT CAGCGTGGCC 
GACGTCGTCA TCGTCGCTGT GTACTTCGCC GTGAACATGG CCGTGGGCGT ATGGTCTTCA 
TGCCGGGCCA GCAGGAACAC AGTGAGTGGC TACTTCCTGG CGGGCCGGGA CATGATGTGG 
CGGCCGATTG GAGCCTCCCT CTTTGCCAGC AGCGAGGGCT CGGGCCTCTT TGTCGGACTG 
GCGGGCTCGG GCGCGGCGGG CGGCCTGGCA GTGGCAGGCT TCGAGTGGCA TGCCACGTAC 
GTGCTGCTGG CCCTGGCCTG GGTGTTTGTG CCCATCTACA TCTCCTCGGA GATTGTCACC 
ATGCCGGAGT ACATCCAGAA GCGCTACGGC GGCCAGCGGA TACGCATGTA CCTGTCTGTC 
CTGTCGCTGC TGCTCTCCAT CTTCACCAAG ATATCGATTG ACCTGTACGC AGGGGCGCTG 
TTCGTGCACA TCTGTCTGGG CTGGAACTTC TACCTCTCCA CCTGCCTCAT GCTCGTCATC 
ACCGCCCTGT ACACCATCGC AGGGGGCCTG GCGGCTGTCA TCTACACCGA CGCCCTGCAG 
ACGCTCATCA TGGTGGTGGG GGCCGTGATC CTCACGGTCA AAGCTTTCCA GCAGATCGGC 
GGGTATGAGC AGCTGGCAGC TGCCTACGCC CAGGCCATCC CCTCCAAGAC CATCTCCAAC 
ACGACGTGCC ACCTGCCGCG GGCAGACGCC ATGCACATGT TCCGAGACCC CGCCACGGGG 
GACCTGCCGT GGACCGGCAT GACCTTCGGC CTGACCATCA TGGCCACCTG GTACTGGTGC 
ACCGACCAGG TCATCGTGCA GCGGTCGCTG TCGGCCCGGG ACCTGAACCA CGCCAAGGGG 
GGCTCCATCC TGGCCAGCTA CCTCAAGATG CTGCCCATGG GCCTGATGGT CATGCCGGGC 
ATGATCAGCC GCGTGCTGTT TCCAGATGAT GTGGGCTGCG TGGTGCCATC CGAGTGCCTG 
CGGGCCTGTG GGGCCGAGAT TGGCTGCTCC AACATCGCCT ACCCCAAGCT GGTCATGGAG 
CTGATGCCCA CAGGTCTGCG GGGGCTGATG GTCGCCGTGA TGATGGCCGC GCTCATGTCC 
TCGCTGACGT CCATCTTTAA CAGCAGCAGC ACCCTCTTCA CCATGGACGT CTGGAGGCGG 
CTGCGGCCCC GCGCCGGCGA GCGGGAGCTG CTGCTGGTGG GACGGCTGGT CATCGTCGTG 
CTCATTGGCG TGAGCGTGGC CTGGATCCCC GTCCTGCAAG GCTCCAACAG CGGGCAGCTC 
TTCATCTACA TGCAGTCGGT GACCAGCTCG CTGGCCCCCC CGGTGACCGC GGTCTTTGTC 
CTGGGCATCT TCTGGCGGCG GGCCAACGAG CAGGGGGCCT TCTGGGGCCT GATGGTGGGG 
CTGGCGGTGG GCGCCTGGAG GCTGGTCCTG GAGTTCCTGC ACCCCGCCCC GCCCTGCGGC 
CACCCCGACG TGCGGCCGGC CCTGCTCCGC ACGGTCCACT ACCTGCACTT CGCCGTGGCG 
CTCTTCGTCC TCAGCGGGGC CGTGGTGGCG GCCGTGAGCC TGCTGACGCC GCCCCCCGCG 
GGCGTCCAGA TCGAGAACCT CACGTGGTGG ACCCTGGCTC GGGACCGGCC CTCGGGGGCC 
AAAACAGGTG ACGGCCCAGC ATCCCAGAAA CACGCCTTCT GGGCCCGGGT CTGCAGCCTC 
AACGCCGTCC TCCTCGTGTG TGTCAACCTC TTCTTTTACG CCTACTTCGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effect of heat stress on performance and expression of selected amino acid and glucose transporters, HSP90, leptin and ghrelin in growing pigs.
Journal of thermal biology5969-76(2016 Jul)
Cervantes M,Cota M,Arce N,Castillo G,Avelar E,Espinoza S,Morales A

Transmissible Gastroenteritis Virus Infection Enhances SGLT1 and GLUT2 Expression to Increase Glucose Uptake.
PloS one11(11)e0165585(2016)
Dai L,Hu WW,Xia L,Xia M,Yang Q

Segmental diversity of electrogenic glucose transport characteristics in the small intestines of weaned pigs.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology163(1)161-9(2012 Sep)
Herrmann J,Schr?der B,Klinger S,Thorenz A,Werner AC,Abel H,Breves G

Histomorphology and small intestinal sodium-dependent glucose transporter 1 gene expression in piglets fed phytic acid and phytase-supplemented diets.
Journal of animal science89(8)2485-90(2011 Aug)
Woyengo TA,Rodriguez-Lecompte JC,Adeola O,Nyachoti CM

Apical Na+-D-glucose cotransporter 1 (SGLT1) activity and protein abundance are expressed along the jejunal crypt-villus axis in the neonatal pig.
American journal of physiology. Gastrointestinal and liver physiology300(1)G60-70(2011 Jan)
Yang C,Albin DM,Wang Z,Stoll B,Lackeyram D,Swanson KC,Yin Y,Tappenden KA,Mine Y,Yada RY,Burrin DG,Fan MZ