Tmem115 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmem115
Entrez Gene ID	56395
Full Name	transmembrane protein 115
Synonyms	C78915,Pl6,Pp6
General protein information	Preferred Names transmembrane protein 115 Names transmembrane protein 115 placental protein 6 protein PL6 homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_019704.2	NP_062678.1	transmembrane protein 115

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009445	XP_307858.3
Caenorhabditis elegans (roundworm)	F11A10.6	NP_001255618.1
Mus musculus (house mouse)	Tmem115	NP_062678.1
Rattus norvegicus (Norway rat)	LOC100910557	XP_003752327.1
Drosophila melanogaster (fruit fly)	CG9536	NP_609033.1
Oryza sativa (rice)	Os04g0103300	NP_001051999.1

Gene Ontology
Bibliography

Related articles in PubMed

TMEM115 is an integral membrane protein of the Golgi complex involved in retrograde transport.
Ong YS, Tran TH, Gounko NV, Hong W
Journal of cell science127(Pt 13)2825-39(2014 Jul)

Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway.
Broglie P, Matsumoto K, Akira S, Brautigan DL, Ninomiya-Tsuji J
The Journal of biological chemistry285(4)2333-9(2010 Jan)

The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
Lerman MI, Minna JD
Cancer research60(21)6116-33(2000 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results establish that TMEM115 is an integral membrane protein of the Golgi stack regulating Golgi-to-ER retrograde transport and is likely to be part of the machinery of the COG complex.
Title: TMEM115 is an integral membrane protein of the Golgi complex involved in retrograde transport.

The following Tmem115 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmem115 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu11439	NM_019704.2 Latest version!	Mus musculus transmembrane protein 115 (Tmem115), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmem115 ( NM_019704.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062678.1 Mus musculus transmembrane protein 115 (Tmem115), mRNA.

Price & Availability↑

CloneID	OMu11439
Clone ID Related Accession (Same CDS sequence)	NM_019704.2
Accession Version	NM_019704.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Mus musculus(house mouse)
Product	transmembrane protein 115
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL672219.7. On Nov 17, 2006 this sequence version replaced NM_019704.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AF134238.1, AK043834.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCAACGCG CCCTACCTGG TGCCCGCCAA CATCTGGGGG CCATCCTGGC CAGCGCCAGC 
GTGGTGGTGA AGGCACTGTG CGCCGTGGTA CTGTTTCTCT ACCTGCTTTC CTTCGCTGTG 
GACACGGGCT GCCTGGCCGT CACCCCAGGC TACCTTTTCC CACCCAACTT CTGGATCTGG 
ACCCTGGCCA CCCACGGGCT CATGGAACAG CACGTGTGGG ACGTGGCCAT TAGCCTGGCC 
ACAGTGGTTG TGGCCGGGCG ATTACTGGAG CCCCTCTGGG GAGCCTTGGA GCTGCTCATC 
TTCTTCTCGG TGGTGAATGT GTCAGTGGGG CTTCTGGGGG CCCTCGCCTA CCTCCTCACC 
TACATGGCTT CCTTCAACTT GGTTTACCTG TTCACTATTC GTATCCACGG CGCCCTGGGT 
TTCCTAGGTG GTGTTCTGGT AGCCCTCAAG CAAACTATGG GAGACTGTGT GGTTCTGCGA 
GTGCCCCAGG TCCGCGTCAG CGTCGTTCCC ATGCTGTTGC TGGCGTTGCT GCTACTCCTC 
CGGTTGGCCA CGCTGCTCCA GAGCCCAGCC CTGGCTTCCT ACGGCTTTGG GCTGCTATCC 
AGTTGGGTGT ATCTTCGCTT CTATCAGCGC CATAGCCGGG GCCGAGGGGA CATGGCTGAC 
CATTTTGCTT TTGCCACCTT CTTCCCGGAG ATCCTGCAAC CGGTGGTGGG GCTGCTAGCG 
AACTTGGTGC ACGGCCTCCT GGTGAAAGTA AAGATATGCC AGAAGACAGT GAAGCGCTAC 
GATGTGGGAG CGCCGTCGTC CATCACTATC AGCCTCCCAG GCACAGACCC TCAAGATGCG 
GAGCGCAGAA GGCAACTAGC CCTAAAGGCT CTCAATGAGC GGCTGAAGAG AGTGGAGGAT 
CAGTCAGCCT GGCCCAGCAT GGATGATGAC GAAGAGGAAG CTGGGGCAAA AACGGACAGT 
CCTCTGCCCT TAGAAGAAGC TTCCACGCCC CCAGGGAAGG TGACCGTCCC GGAATCCAGT 
CTCATCACCT TGGAGACAGC TCCCCTACTC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062678.1
CDS	535..1587
Translation	MQRALPGARQHLGAILASASVVVKALCAVVLFLYLLSFAVDTGCLAVTPGYLFPPNFWIWTLATHGLMEQHVWDVAISLATVVVAGRLLEPLWGALELLIFFSVVNVSVGLLGALAYLLTYMASFNLVYLFTIRIHGALGFLGGVLVALKQTMGDCVVLRVPQVRVSVVPMLLLALLLLLRLATLLQSPALASYGFGLLSSWVYLRFYQRHSRGRGDMADHFAFATFFPEILQPVVGLLANLVHGLLVKVKICQKTVKRYDVGAPSSITISLPGTDPQDAERRRQLALKALNERLKRVEDQSAWPSMDDDEEEAGAKTDSPLPLEEASTPPGKVTVPESSLITLETAPLL

Target ORF information:

RefSeq Version	NM_019704.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protein 115 (Tmem115), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019704.2

ORF Insert Sequence:

ATGCAACGCG CCCTACCTGG TGCCCGCCAA CATCTGGGGG CCATCCTGGC CAGCGCCAGC 
GTGGTGGTGA AGGCACTGTG CGCCGTGGTA CTGTTTCTCT ACCTGCTTTC CTTCGCTGTG 
GACACGGGCT GCCTGGCCGT CACCCCAGGC TACCTTTTCC CACCCAACTT CTGGATCTGG 
ACCCTGGCCA CCCACGGGCT CATGGAACAG CACGTGTGGG ACGTGGCCAT TAGCCTGGCC 
ACAGTGGTTG TGGCCGGGCG ATTACTGGAG CCCCTCTGGG GAGCCTTGGA GCTGCTCATC 
TTCTTCTCGG TGGTGAATGT GTCAGTGGGG CTTCTGGGGG CCCTCGCCTA CCTCCTCACC 
TACATGGCTT CCTTCAACTT GGTTTACCTG TTCACTATTC GTATCCACGG CGCCCTGGGT 
TTCCTAGGTG GTGTTCTGGT AGCCCTCAAG CAAACTATGG GAGACTGTGT GGTTCTGCGA 
GTGCCCCAGG TCCGCGTCAG CGTCGTTCCC ATGCTGTTGC TGGCGTTGCT GCTACTCCTC 
CGGTTGGCCA CGCTGCTCCA GAGCCCAGCC CTGGCTTCCT ACGGCTTTGG GCTGCTATCC 
AGTTGGGTGT ATCTTCGCTT CTATCAGCGC CATAGCCGGG GCCGAGGGGA CATGGCTGAC 
CATTTTGCTT TTGCCACCTT CTTCCCGGAG ATCCTGCAAC CGGTGGTGGG GCTGCTAGCG 
AACTTGGTGC ACGGCCTCCT GGTGAAAGTA AAGATATGCC AGAAGACAGT GAAGCGCTAC 
GATGTGGGAG CGCCGTCGTC CATCACTATC AGCCTCCCAG GCACAGACCC TCAAGATGCG 
GAGCGCAGAA GGCAACTAGC CCTAAAGGCT CTCAATGAGC GGCTGAAGAG AGTGGAGGAT 
CAGTCAGCCT GGCCCAGCAT GGATGATGAC GAAGAGGAAG CTGGGGCAAA AACGGACAGT 
CCTCTGCCCT TAGAAGAAGC TTCCACGCCC CCAGGGAAGG TGACCGTCCC GGAATCCAGT 
CTCATCACCT TGGAGACAGC TCCCCTACTC TAG