NPTX2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NPTX2
Entrez Gene ID	4885
Full Name	neuronal pentraxin 2
Synonyms	NARP,NP-II,NP2
General protein information	Preferred Names neuronal pentraxin 2 Names neuronal pentraxin-2 apexin neuronal activity-regulated pentaxin neuronal pentraxin II
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q22.1
Summary	This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009].
Disorder MIM:	600750

mRNA and Protein(s)

mRNA	Protein	Name
NM_002523.3	NP_002514.1	neuronal pentraxin-2 precursor
NM_002523.2	NP_002514.1	neuronal pentraxin-2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	NPTX2	NP_002514.1
Bos taurus (cattle)	NPTX2	XP_002698264.1
	NPTX2	XP_001111081.2
Rattus norvegicus (Norway rat)	Nptx2	NP_001029371.1
Gallus gallus (chicken)	NPTX2	XP_414750.3
Mus musculus (house mouse)	Nptx2	NP_058069.1
Danio rerio (zebrafish)	nptx2a	NP_001103238.1
Danio rerio (zebrafish)	nptx2b	NP_001165055.1
Pan troglodytes (chimpanzee)	NPTX2	XP_001136152.2
Canis lupus familiaris (dog)	NPTX2	XP_003639131.1
Xenopus tropicalis (tropical clawed frog)	nptx2	NP_001096304.1

Gene Ontology
Bibliography

Related articles in PubMed

Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions.
Muczynski V, Aym? G, Regnault V, Vasse M, Borgel D, Legendre P, Bazaa A, Harel A, Loubi?re C, Lenting PJ, Denis CV, Christophe OD
Blood129(17)2443-2454(2017 04)

NPTX2 and cognitive dysfunction in Alzheimer's Disease.
Xiao MF, Xu D, Craig MT, Pelkey KA, Chien CC, Shi Y, Zhang J, Resnick S, Pletnikova O, Salmon D, Brewer J, Edland S, Wegiel J, Tycko B, Savonenko A, Reeves RH, Troncoso JC, McBain CJ, Galasko D, Worley PF
eLife6(2017 Mar)

Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses.
Lee SJ, Wei M, Zhang C, Maxeiner S, Pak C, Calado Botelho S, Trotter J, Sterky FH, S?dhof TC
The Journal of neuroscience : the official journal of the Society for Neuroscience37(5)1062-1080(2017 Feb)

Neuronal Pentraxin 2 predicts medial temporal atrophy and memory decline across the Alzheimer's disease spectrum.
Swanson A, Willette AA,
Brain, behavior, and immunity58201-208(2016 Nov)

NPTX2 is associated with neoadjuvant therapy response in rectal cancer.
Karagkounis G, Thai L, DeVecchio J, Gantt GA, Duraes L, Pai RK, Kalady MF
The Journal of surgical research202(1)112-7(2016 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PTX2 was identified PTX2 as a novel partner for FX, and both proteins cooperated to prevent their SR-AI-mediated uptake by macrophages.
Title: Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions.

NPTX2 in human cerebrospinal fluid is reduced in subjects with Alzheimer's disease and shows robust correlations with cognitive performance and hippocampal volume.
Title: NPTX2 and cognitive dysfunction in Alzheimer's Disease.

Neuronal pentraxin 2 predicts medial temporal atrophy and memory decline across the Alzheimer's disease spectrum. This research may advance the current understanding of Alzheimer's disease etiopathogenesis, while expanding early diagnostic techniques through the use of novel pro-inflammatory biomarkers, such as NPTX2.
Title: Neuronal Pentraxin 2 predicts medial temporal atrophy and memory decline across the Alzheimer's disease spectrum.

Decreased NPTX2 expression in rectal adenocarcinomas is associated with improved response to neoadjuvant chemoradiation and improved prognosis.
Title: NPTX2 is associated with neoadjuvant therapy response in rectal cancer.

we show that NPTX2 is a marker of poor prognosis for neuroblastoma patients.
Title: The Neuronal Pentraxin-2 Pathway Is an Unrecognized Target in Human Neuroblastoma, Which Also Offers Prognostic Value in Patients.

The following NPTX2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NPTX2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17961	NM_002523.3 Latest version!	Homo sapiens neuronal pentraxin 2 (NPTX2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu17961	NM_002523.2	Homo sapiens neuronal pentraxin 2 (NPTX2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NPTX2 ( NM_002523.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002514.1 Homo sapiens neuronal pentraxin 2 (NPTX2), mRNA.

Price & Availability↑

CloneID	OHu17961
Clone ID Related Accession (Same CDS sequence)	NM_002523.3 , NM_002523.2
Accession Version	NM_002523.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	neuronal pentraxin-2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI561105.1 and BC009924.2. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_002523.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC035339.1, BC034781.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265634.4/ ENSP00000265634.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGGCGC TGCTGGCCGC CAGCGTGGCG CTCGCCGTGG CCGCTGGGGC CCAGGACAGC 
CCGGCGCCCG GTAGCCGCTT CGTGTGCACG GCACTGCCCC CAGAGGCGGT GCACGCCGGC 
TGCCCGCTGC CCGCGATGCC CATGCAGGGC GGCGCGCAGA GTCCCGAGGA GGAGCTGAGG 
GCCGCGGTGC TGCAGCTGCG CGAGACCGTC GTGCAGCAGA AGGAGACGCT GGGCGCGCAG 
CGCGAGGCCA TCCGCGAGCT CACGGGCAAG CTAGCGCGCT GCGAGGGGCT GGCGGGCGGC 
AAGGCGCGCG GCGCGGGGGC CACGGGCAAG GACACTATGG GCGACCTGCC GCGGGACCCC 
GGCCACGTCG TGGAGCAGCT CAGCCGCTCG CTGCAGACCC TCAAGGACCG CCTGGAGAGC 
CTCGAGCACC AGCTCAGAGC AAACGTGTCC AATGCTGGGC TGCCCGGCGA CTTCCGCGAG 
GTGCTCCAGC AGCGGCTGGG GGAGCTGGAG AGGCAGCTTC TGCGCAAGGT GGCAGAGCTG 
GAGGACGAGA AGTCCCTGCT GCACAATGAG ACCTCGGCTC ACCGGCAGAA GACCGAGAGC 
ACCCTGAACG CGCTGCTGCA GAGGGTCACC GAGCTGGAGC GAGGCAATAG CGCCTTTAAG 
TCACCAGATG CGTTCAAGGT GTCCCTCCCA CTCCGCACAA ACTACCTATA CGGCAAGATC 
AAGAAGACGC TGCCTGAGCT GTACGCCTTC ACCATCTGCC TGTGGCTGCG GTCCAGCGCC 
TCACCAGGCA TTGGCACCCC CTTCTCCTAT GCGGTGCCAG GGCAGGCCAA CGAGATCGTG 
CTGATCGAGT GGGGCAACAA CCCCATCGAG CTGCTCATCA ACGACAAGGT TGCGCAGCTG 
CCCCTGTTTG TCAGTGACGG CAAGTGGCAC CACATCTGTG TCACCTGGAC GACACGGGAT 
GGCATGTGGG AGGCATTCCA GGACGGAGAG AAGCTGGGCA CTGGGGAGAA CCTGGCCCCC 
TGGCACCCCA TCAAGCCCGG GGGCGTGCTG ATCCTTGGAC AAGAGCAGGA CACCGTGGGG 
GGTAGGTTTG ATGCCACTCA GGCATTTGTC GGGGAGCTCA GCCAGTTCAA CATATGGGAC 
CGCGTCCTTC GCGCACAAGA AATTGTCAAC ATCGCCAACT GCTCCACAAA CATGCCGGGC 
AACATCATCC CGTGGGTGGA CAATAACGTC GATGTGTTCG GAGGGGCCTC CAAGTGGCCC 
GTGGAGACGT GTGAGGAGCG TCTCCTTGAC TTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002514.1
CDS	178..1473
Translation	MLALLAASVALAVAAGAQDSPAPGSRFVCTALPPEAVHAGCPLPAMPMQGGAQSPEEELRAAVLQLRETVVQQKETLGAQREAIRELTGKLARCEGLAGGKARGAGATGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLEHQLRANVSNAGLPGDFREVLQQRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIVNIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL

Target ORF information:

RefSeq Version	NM_002523.3
Organism	Homo sapiens(human)
Definition	Homo sapiens neuronal pentraxin 2 (NPTX2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002523.3

ORF Insert Sequence:

ATGCTGGCGC TGCTGGCCGC CAGCGTGGCG CTCGCCGTGG CCGCTGGGGC CCAGGACAGC 
CCGGCGCCCG GTAGCCGCTT CGTGTGCACG GCACTGCCCC CAGAGGCGGT GCACGCCGGC 
TGCCCGCTGC CCGCGATGCC CATGCAGGGC GGCGCGCAGA GTCCCGAGGA GGAGCTGAGG 
GCCGCGGTGC TGCAGCTGCG CGAGACCGTC GTGCAGCAGA AGGAGACGCT GGGCGCGCAG 
CGCGAGGCCA TCCGCGAGCT CACGGGCAAG CTAGCGCGCT GCGAGGGGCT GGCGGGCGGC 
AAGGCGCGCG GCGCGGGGGC CACGGGCAAG GACACTATGG GCGACCTGCC GCGGGACCCC 
GGCCACGTCG TGGAGCAGCT CAGCCGCTCG CTGCAGACCC TCAAGGACCG CCTGGAGAGC 
CTCGAGCACC AGCTCAGAGC AAACGTGTCC AATGCTGGGC TGCCCGGCGA CTTCCGCGAG 
GTGCTCCAGC AGCGGCTGGG GGAGCTGGAG AGGCAGCTTC TGCGCAAGGT GGCAGAGCTG 
GAGGACGAGA AGTCCCTGCT GCACAATGAG ACCTCGGCTC ACCGGCAGAA GACCGAGAGC 
ACCCTGAACG CGCTGCTGCA GAGGGTCACC GAGCTGGAGC GAGGCAATAG CGCCTTTAAG 
TCACCAGATG CGTTCAAGGT GTCCCTCCCA CTCCGCACAA ACTACCTATA CGGCAAGATC 
AAGAAGACGC TGCCTGAGCT GTACGCCTTC ACCATCTGCC TGTGGCTGCG GTCCAGCGCC 
TCACCAGGCA TTGGCACCCC CTTCTCCTAT GCGGTGCCAG GGCAGGCCAA CGAGATCGTG 
CTGATCGAGT GGGGCAACAA CCCCATCGAG CTGCTCATCA ACGACAAGGT TGCGCAGCTG 
CCCCTGTTTG TCAGTGACGG CAAGTGGCAC CACATCTGTG TCACCTGGAC GACACGGGAT 
GGCATGTGGG AGGCATTCCA GGACGGAGAG AAGCTGGGCA CTGGGGAGAA CCTGGCCCCC 
TGGCACCCCA TCAAGCCCGG GGGCGTGCTG ATCCTTGGAC AAGAGCAGGA CACCGTGGGG 
GGTAGGTTTG ATGCCACTCA GGCATTTGTC GGGGAGCTCA GCCAGTTCAA CATATGGGAC 
CGCGTCCTTC GCGCACAAGA AATTGTCAAC ATCGCCAACT GCTCCACAAA CATGCCGGGC 
AACATCATCC CGTGGGTGGA CAATAACGTC GATGTGTTCG GAGGGGCCTC CAAGTGGCCC 
GTGGAGACGT GTGAGGAGCG TCTCCTTGAC TTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NPTX2 ( NM_002523.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002514.1 Homo sapiens neuronal pentraxin 2 (NPTX2), mRNA.

Price & Availability↑

CloneID	OHu17961
Clone ID Related Accession (Same CDS sequence)	NM_002523.3 , NM_002523.2
Accession Version	NM_002523.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	neuronal pentraxin-2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI561105.1 and BC009924.2. This sequence is a reference standard in the RefSeqGene project. On Feb 18, 2009 this sequence version replaced NM_002523.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC035339.1, BC034781.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGGCGC TGCTGGCCGC CAGCGTGGCG CTCGCCGTGG CCGCTGGGGC CCAGGACAGC 
CCGGCGCCCG GTAGCCGCTT CGTGTGCACG GCACTGCCCC CAGAGGCGGT GCACGCCGGC 
TGCCCGCTGC CCGCGATGCC CATGCAGGGC GGCGCGCAGA GTCCCGAGGA GGAGCTGAGG 
GCCGCGGTGC TGCAGCTGCG CGAGACCGTC GTGCAGCAGA AGGAGACGCT GGGCGCGCAG 
CGCGAGGCCA TCCGCGAGCT CACGGGCAAG CTAGCGCGCT GCGAGGGGCT GGCGGGCGGC 
AAGGCGCGCG GCGCGGGGGC CACGGGCAAG GACACTATGG GCGACCTGCC GCGGGACCCC 
GGCCACGTCG TGGAGCAGCT CAGCCGCTCG CTGCAGACCC TCAAGGACCG CCTGGAGAGC 
CTCGAGCACC AGCTCAGAGC AAACGTGTCC AATGCTGGGC TGCCCGGCGA CTTCCGCGAG 
GTGCTCCAGC AGCGGCTGGG GGAGCTGGAG AGGCAGCTTC TGCGCAAGGT GGCAGAGCTG 
GAGGACGAGA AGTCCCTGCT GCACAATGAG ACCTCGGCTC ACCGGCAGAA GACCGAGAGC 
ACCCTGAACG CGCTGCTGCA GAGGGTCACC GAGCTGGAGC GAGGCAATAG CGCCTTTAAG 
TCACCAGATG CGTTCAAGGT GTCCCTCCCA CTCCGCACAA ACTACCTATA CGGCAAGATC 
AAGAAGACGC TGCCTGAGCT GTACGCCTTC ACCATCTGCC TGTGGCTGCG GTCCAGCGCC 
TCACCAGGCA TTGGCACCCC CTTCTCCTAT GCGGTGCCAG GGCAGGCCAA CGAGATCGTG 
CTGATCGAGT GGGGCAACAA CCCCATCGAG CTGCTCATCA ACGACAAGGT TGCGCAGCTG 
CCCCTGTTTG TCAGTGACGG CAAGTGGCAC CACATCTGTG TCACCTGGAC GACACGGGAT 
GGCATGTGGG AGGCATTCCA GGACGGAGAG AAGCTGGGCA CTGGGGAGAA CCTGGCCCCC 
TGGCACCCCA TCAAGCCCGG GGGCGTGCTG ATCCTTGGAC AAGAGCAGGA CACCGTGGGG 
GGTAGGTTTG ATGCCACTCA GGCATTTGTC GGGGAGCTCA GCCAGTTCAA CATATGGGAC 
CGCGTCCTTC GCGCACAAGA AATTGTCAAC ATCGCCAACT GCTCCACAAA CATGCCGGGC 
AACATCATCC CGTGGGTGGA CAATAACGTC GATGTGTTCG GAGGGGCCTC CAAGTGGCCC 
GTGGAGACGT GTGAGGAGCG TCTCCTTGAC TTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002514.1
CDS	178..1473
Translation	MLALLAASVALAVAAGAQDSPAPGSRFVCTALPPEAVHAGCPLPAMPMQGGAQSPEEELRAAVLQLRETVVQQKETLGAQREAIRELTGKLARCEGLAGGKARGAGATGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLEHQLRANVSNAGLPGDFREVLQQRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIVNIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL

Target ORF information:

RefSeq Version	NM_002523.2
Organism	Homo sapiens(human)
Definition	Homo sapiens neuronal pentraxin 2 (NPTX2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002523.2

ORF Insert Sequence:

ATGCTGGCGC TGCTGGCCGC CAGCGTGGCG CTCGCCGTGG CCGCTGGGGC CCAGGACAGC 
CCGGCGCCCG GTAGCCGCTT CGTGTGCACG GCACTGCCCC CAGAGGCGGT GCACGCCGGC 
TGCCCGCTGC CCGCGATGCC CATGCAGGGC GGCGCGCAGA GTCCCGAGGA GGAGCTGAGG 
GCCGCGGTGC TGCAGCTGCG CGAGACCGTC GTGCAGCAGA AGGAGACGCT GGGCGCGCAG 
CGCGAGGCCA TCCGCGAGCT CACGGGCAAG CTAGCGCGCT GCGAGGGGCT GGCGGGCGGC 
AAGGCGCGCG GCGCGGGGGC CACGGGCAAG GACACTATGG GCGACCTGCC GCGGGACCCC 
GGCCACGTCG TGGAGCAGCT CAGCCGCTCG CTGCAGACCC TCAAGGACCG CCTGGAGAGC 
CTCGAGCACC AGCTCAGAGC AAACGTGTCC AATGCTGGGC TGCCCGGCGA CTTCCGCGAG 
GTGCTCCAGC AGCGGCTGGG GGAGCTGGAG AGGCAGCTTC TGCGCAAGGT GGCAGAGCTG 
GAGGACGAGA AGTCCCTGCT GCACAATGAG ACCTCGGCTC ACCGGCAGAA GACCGAGAGC 
ACCCTGAACG CGCTGCTGCA GAGGGTCACC GAGCTGGAGC GAGGCAATAG CGCCTTTAAG 
TCACCAGATG CGTTCAAGGT GTCCCTCCCA CTCCGCACAA ACTACCTATA CGGCAAGATC 
AAGAAGACGC TGCCTGAGCT GTACGCCTTC ACCATCTGCC TGTGGCTGCG GTCCAGCGCC 
TCACCAGGCA TTGGCACCCC CTTCTCCTAT GCGGTGCCAG GGCAGGCCAA CGAGATCGTG 
CTGATCGAGT GGGGCAACAA CCCCATCGAG CTGCTCATCA ACGACAAGGT TGCGCAGCTG 
CCCCTGTTTG TCAGTGACGG CAAGTGGCAC CACATCTGTG TCACCTGGAC GACACGGGAT 
GGCATGTGGG AGGCATTCCA GGACGGAGAG AAGCTGGGCA CTGGGGAGAA CCTGGCCCCC 
TGGCACCCCA TCAAGCCCGG GGGCGTGCTG ATCCTTGGAC AAGAGCAGGA CACCGTGGGG 
GGTAGGTTTG ATGCCACTCA GGCATTTGTC GGGGAGCTCA GCCAGTTCAA CATATGGGAC 
CGCGTCCTTC GCGCACAAGA AATTGTCAAC ATCGCCAACT GCTCCACAAA CATGCCGGGC 
AACATCATCC CGTGGGTGGA CAATAACGTC GATGTGTTCG GAGGGGCCTC CAAGTGGCCC 
GTGGAGACGT GTGAGGAGCG TCTCCTTGAC TTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions.
Blood129(17)2443-2454(2017 04)
Muczynski V,Aym? G,Regnault V,Vasse M,Borgel D,Legendre P,Bazaa A,Harel A,Loubi?re C,Lenting PJ,Denis CV,Christophe OD

NPTX2 and cognitive dysfunction in Alzheimer's Disease.
eLife6(2017 Mar)
Xiao MF,Xu D,Craig MT,Pelkey KA,Chien CC,Shi Y,Zhang J,Resnick S,Pletnikova O,Salmon D,Brewer J,Edland S,Wegiel J,Tycko B,Savonenko A,Reeves RH,Troncoso JC,McBain CJ,Galasko D,Worley PF

Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience37(5)1062-1080(2017 Feb)
Lee SJ,Wei M,Zhang C,Maxeiner S,Pak C,Calado Botelho S,Trotter J,Sterky FH,S?dhof TC

Neuronal Pentraxin 2 predicts medial temporal atrophy and memory decline across the Alzheimer's disease spectrum.
Brain, behavior, and immunity58201-208(2016 Nov)
Swanson A,Willette AA,

NPTX2 is associated with neoadjuvant therapy response in rectal cancer.
The Journal of surgical research202(1)112-7(2016 May)
Karagkounis G,Thai L,DeVecchio J,Gantt GA,Duraes L,Pai RK,Kalady MF

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

NPTX2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報