IMPDH2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IMPDH2
Entrez Gene ID	3615
Full Name	inosine monophosphate dehydrogenase 2
Synonyms	IMPD2,IMPDH-II
General protein information	Preferred Names inosine monophosphate dehydrogenase 2 Names inosine-5'-monophosphate dehydrogenase 2 IMP (inosine 5'-monophosphate) dehydrogenase 2 IMP (inosine monophosphate) dehydrogenase 2 IMP oxireductase 2 IMPD 2 IMPDH 2 inosine 5' phosphate dehydrogenase 2 inosine monophosphate dehydrogenase type II
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p21.31
Summary	This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008].
Disorder MIM:	146691
Disorder Html:	[IMPDH2 enzyme activity, variation in] (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017006349.1	XP_016861838.1	inosine-5'-monophosphate dehydrogenase 2 isoform X2
NM_000884.2	NP_000875.2	inosine-5'-monophosphate dehydrogenase 2
XM_006713128.3	XP_006713191.1	inosine-5'-monophosphate dehydrogenase 2 isoform X1
XM_017006350.1	XP_016861839.1	inosine-5'-monophosphate dehydrogenase 2 isoform X3
NM_000884.3	NP_000875.2	inosine-5'-monophosphate dehydrogenase 2

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	impdh2	NP_958872.1
Xenopus tropicalis (tropical clawed frog)	impdh2	NP_001008066.1
Homo sapiens (human)	IMPDH2	NP_000875.2
Pan troglodytes (chimpanzee)	IMPDH2	XP_516452.3
	IMPDH2	XP_001110652.2
Canis lupus familiaris (dog)	IMPDH2	XP_005632626.1
Bos taurus (cattle)	IMPDH2	NP_001029588.1
Mus musculus (house mouse)	Impdh2	NP_035960.2
Rattus norvegicus (Norway rat)	Impdh2	NP_954530.1
Gallus gallus (chicken)	IMPDH2	NP_001025772.1
Mus musculus (house mouse)	Gm15210	XP_001478203.3

Gene Ontology
Bibliography

Related articles in PubMed

CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis.
Lin R, Mo Y, Zha H, Qu Z, Xie P, Zhu ZJ, Xu Y, Xiong Y, Guan KL
Molecular cell68(1)198-209.e6(2017 Oct)

High expression of IMPDH2 is associated with aggressive features and poor prognosis of primary nasopharyngeal carcinoma.
Xu Y, Zheng Z, Gao Y, Duan S, Chen C, Rong J, Wang K, Yun M, Weng H, Ye S, Zhang J
Scientific reports7(1)745(2017 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) is an intracellular target of the PPIA-Sanglifehrin A binary complex.
Title: IMPDH2 Is an Intracellular Target of the Cyclophilin A and Sanglifehrin A Complex.

Taking together, these results indicate that natural product myricetin exhibits potent anti-leukemia activity by interfering with purine nucleotides biosynthetic pathway through the suppression of hIMPDH1/2 catalytic activity.
Title: Myricetin is a novel inhibitor of human inosine 5'-monophosphate dehydrogenase with anti-leukemia activity.

Rod and ring formation might be an adaptive homeostatic mechanism, allowing IMPDH to sense changes in the one-carbon folate pathway.
Title: 'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway.

The findings suggest that overexpressed IMPDH2 can be used as a biomarker for kidney and bladder cancer diagnosis and is a potential therapeutic target for the diseases
Title: Elevated expression of IMPDH2 is associated with progression of kidney and bladder cancer.

IMPDH2 is directly involved in the development of chemoresistance and radioresistance in osteosarcoma cells.
Title: IMPDH2 mediate radioresistance and chemoresistance in osteosarcoma cells.

The following IMPDH2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IMPDH2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19610	NM_000884.3 Latest version!	Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu37205	XM_006713128.3 Latest version!	Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu94152	XM_017006349.1 Latest version!	Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu94153	XM_017006350.1 Latest version!	Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu19610	NM_000884.2	Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IMPDH2 ( NM_000884.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_000875.2 Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), mRNA.

Price & Availability↑

CloneID	OHu19610
Clone ID Related Accession (Same CDS sequence)	NM_000884.2 , NM_000884.3
Accession Version	NM_000884.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	inosine-5'-monophosphate dehydrogenase 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC137630.9, J04208.1 and BC009236.2. This sequence is a reference standard in the RefSeqGene project. On Jun 3, 2005 this sequence version replaced NM_000884.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.683833.1, SRR1163657.428088.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCCGACT ACCTGATTAG TGGGGGCACG TCCTACGTGC CAGACGACGG ACTCACAGCA 
CAGCAGCTCT TCAACTGCGG AGACGGCCTC ACCTACAATG ACTTTCTCAT TCTCCCTGGG 
TACATCGACT TCACTGCAGA CCAGGTGGAC CTGACTTCTG CTCTGACCAA GAAAATCACT 
CTTAAGACCC CACTGGTTTC CTCTCCCATG GACACAGTCA CAGAGGCTGG GATGGCCATA 
GCAATGGCGC TTACAGGCGG TATTGGCTTC ATCCACCACA ACTGTACACC TGAATTCCAG 
GCCAATGAAG TTCGGAAAGT GAAGAAATAT GAACAGGGAT TCATCACAGA CCCTGTGGTC 
CTCAGCCCCA AGGATCGCGT GCGGGATGTT TTTGAGGCCA AGGCCCGGCA TGGTTTCTGC 
GGTATCCCAA TCACAGACAC AGGCCGGATG GGGAGCCGCT TGGTGGGCAT CATCTCCTCC 
AGGGACATTG ATTTTCTCAA AGAGGAGGAA CATGACTGTT TCTTGGAAGA GATAATGACA 
AAGAGGGAAG ACTTGGTGGT AGCCCCTGCA GGCATCACAC TGAAGGAGGC AAATGAAATT 
CTGCAGCGCA GCAAGAAGGG AAAGTTGCCC ATTGTAAATG AAGATGATGA GCTTGTGGCC 
ATCATTGCCC GGACAGACCT GAAGAAGAAT CGGGACTACC CACTAGCCTC CAAAGATGCC 
AAGAAACAGC TGCTGTGTGG GGCAGCCATT GGCACTCATG AGGATGACAA GTATAGGCTG 
GACTTGCTCG CCCAGGCTGG TGTGGATGTA GTGGTTTTGG ACTCTTCCCA GGGAAATTCC 
ATCTTCCAGA TCAATATGAT CAAGTACATC AAAGACAAAT ACCCTAATCT CCAAGTCATT 
GGAGGCAATG TGGTCACTGC TGCCCAGGCC AAGAACCTCA TTGATGCAGG TGTGGATGCC 
CTGCGGGTGG GCATGGGAAG TGGCTCCATC TGCATTACGC AGGAAGTGCT GGCCTGTGGG 
CGGCCCCAAG CAACAGCAGT GTACAAGGTG TCAGAGTATG CACGGCGCTT TGGTGTTCCG 
GTCATTGCTG ATGGAGGAAT CCAAAATGTG GGTCATATTG CGAAAGCCTT GGCCCTTGGG 
GCCTCCACAG TCATGATGGG CTCTCTCCTG GCTGCCACCA CTGAGGCCCC TGGTGAATAC 
TTCTTTTCCG ATGGGATCCG GCTAAAGAAA TATCGCGGTA TGGGTTCTCT CGATGCCATG 
GACAAGCACC TCAGCAGCCA GAACAGATAT TTCAGTGAAG CTGACAAAAT CAAAGTGGCC 
CAGGGAGTGT CTGGTGCTGT GCAGGACAAA GGGTCAATCC ACAAATTTGT CCCTTACCTG 
ATTGCTGGCA TCCAACACTC ATGCCAGGAC ATTGGTGCCA AGAGCTTGAC CCAAGTCCGA 
GCCATGATGT ACTCTGGGGA GCTTAAGTTT GAGAAGAGAA CGTCCTCAGC CCAGGTGGAA 
GGTGGCGTCC ATAGCCTCCA TTCGTATGAG AAGCGGCTTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000875.2
CDS	93..1637
Translation	MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF

Target ORF information:

RefSeq Version	NM_000884.2
Organism	Homo sapiens(human)
Definition	Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000884.2

ORF Insert Sequence:

ATGGCCGACT ACCTGATTAG TGGGGGCACG TCCTACGTGC CAGACGACGG ACTCACAGCA 
CAGCAGCTCT TCAACTGCGG AGACGGCCTC ACCTACAATG ACTTTCTCAT TCTCCCTGGG 
TACATCGACT TCACTGCAGA CCAGGTGGAC CTGACTTCTG CTCTGACCAA GAAAATCACT 
CTTAAGACCC CACTGGTTTC CTCTCCCATG GACACAGTCA CAGAGGCTGG GATGGCCATA 
GCAATGGCGC TTACAGGCGG TATTGGCTTC ATCCACCACA ACTGTACACC TGAATTCCAG 
GCCAATGAAG TTCGGAAAGT GAAGAAATAT GAACAGGGAT TCATCACAGA CCCTGTGGTC 
CTCAGCCCCA AGGATCGCGT GCGGGATGTT TTTGAGGCCA AGGCCCGGCA TGGTTTCTGC 
GGTATCCCAA TCACAGACAC AGGCCGGATG GGGAGCCGCT TGGTGGGCAT CATCTCCTCC 
AGGGACATTG ATTTTCTCAA AGAGGAGGAA CATGACTGTT TCTTGGAAGA GATAATGACA 
AAGAGGGAAG ACTTGGTGGT AGCCCCTGCA GGCATCACAC TGAAGGAGGC AAATGAAATT 
CTGCAGCGCA GCAAGAAGGG AAAGTTGCCC ATTGTAAATG AAGATGATGA GCTTGTGGCC 
ATCATTGCCC GGACAGACCT GAAGAAGAAT CGGGACTACC CACTAGCCTC CAAAGATGCC 
AAGAAACAGC TGCTGTGTGG GGCAGCCATT GGCACTCATG AGGATGACAA GTATAGGCTG 
GACTTGCTCG CCCAGGCTGG TGTGGATGTA GTGGTTTTGG ACTCTTCCCA GGGAAATTCC 
ATCTTCCAGA TCAATATGAT CAAGTACATC AAAGACAAAT ACCCTAATCT CCAAGTCATT 
GGAGGCAATG TGGTCACTGC TGCCCAGGCC AAGAACCTCA TTGATGCAGG TGTGGATGCC 
CTGCGGGTGG GCATGGGAAG TGGCTCCATC TGCATTACGC AGGAAGTGCT GGCCTGTGGG 
CGGCCCCAAG CAACAGCAGT GTACAAGGTG TCAGAGTATG CACGGCGCTT TGGTGTTCCG 
GTCATTGCTG ATGGAGGAAT CCAAAATGTG GGTCATATTG CGAAAGCCTT GGCCCTTGGG 
GCCTCCACAG TCATGATGGG CTCTCTCCTG GCTGCCACCA CTGAGGCCCC TGGTGAATAC 
TTCTTTTCCG ATGGGATCCG GCTAAAGAAA TATCGCGGTA TGGGTTCTCT CGATGCCATG 
GACAAGCACC TCAGCAGCCA GAACAGATAT TTCAGTGAAG CTGACAAAAT CAAAGTGGCC 
CAGGGAGTGT CTGGTGCTGT GCAGGACAAA GGGTCAATCC ACAAATTTGT CCCTTACCTG 
ATTGCTGGCA TCCAACACTC ATGCCAGGAC ATTGGTGCCA AGAGCTTGAC CCAAGTCCGA 
GCCATGATGT ACTCTGGGGA GCTTAAGTTT GAGAAGAGAA CGTCCTCAGC CCAGGTGGAA 
GGTGGCGTCC ATAGCCTCCA TTCGTATGAG AAGCGGCTTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IMPDH2 ( NM_000884.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000875.2 Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), mRNA.

Price & Availability↑

CloneID	OHu19610
Clone ID Related Accession (Same CDS sequence)	NM_000884.2 , NM_000884.3
Accession Version	NM_000884.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	inosine-5'-monophosphate dehydrogenase 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC137630.9, J04208.1 and BC009236.2. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_000884.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.225288.1, SRR3476690.1107078.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000326739.9/ ENSP00000321584.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGACT ACCTGATTAG TGGGGGCACG TCCTACGTGC CAGACGACGG ACTCACAGCA 
CAGCAGCTCT TCAACTGCGG AGACGGCCTC ACCTACAATG ACTTTCTCAT TCTCCCTGGG 
TACATCGACT TCACTGCAGA CCAGGTGGAC CTGACTTCTG CTCTGACCAA GAAAATCACT 
CTTAAGACCC CACTGGTTTC CTCTCCCATG GACACAGTCA CAGAGGCTGG GATGGCCATA 
GCAATGGCGC TTACAGGCGG TATTGGCTTC ATCCACCACA ACTGTACACC TGAATTCCAG 
GCCAATGAAG TTCGGAAAGT GAAGAAATAT GAACAGGGAT TCATCACAGA CCCTGTGGTC 
CTCAGCCCCA AGGATCGCGT GCGGGATGTT TTTGAGGCCA AGGCCCGGCA TGGTTTCTGC 
GGTATCCCAA TCACAGACAC AGGCCGGATG GGGAGCCGCT TGGTGGGCAT CATCTCCTCC 
AGGGACATTG ATTTTCTCAA AGAGGAGGAA CATGACTGTT TCTTGGAAGA GATAATGACA 
AAGAGGGAAG ACTTGGTGGT AGCCCCTGCA GGCATCACAC TGAAGGAGGC AAATGAAATT 
CTGCAGCGCA GCAAGAAGGG AAAGTTGCCC ATTGTAAATG AAGATGATGA GCTTGTGGCC 
ATCATTGCCC GGACAGACCT GAAGAAGAAT CGGGACTACC CACTAGCCTC CAAAGATGCC 
AAGAAACAGC TGCTGTGTGG GGCAGCCATT GGCACTCATG AGGATGACAA GTATAGGCTG 
GACTTGCTCG CCCAGGCTGG TGTGGATGTA GTGGTTTTGG ACTCTTCCCA GGGAAATTCC 
ATCTTCCAGA TCAATATGAT CAAGTACATC AAAGACAAAT ACCCTAATCT CCAAGTCATT 
GGAGGCAATG TGGTCACTGC TGCCCAGGCC AAGAACCTCA TTGATGCAGG TGTGGATGCC 
CTGCGGGTGG GCATGGGAAG TGGCTCCATC TGCATTACGC AGGAAGTGCT GGCCTGTGGG 
CGGCCCCAAG CAACAGCAGT GTACAAGGTG TCAGAGTATG CACGGCGCTT TGGTGTTCCG 
GTCATTGCTG ATGGAGGAAT CCAAAATGTG GGTCATATTG CGAAAGCCTT GGCCCTTGGG 
GCCTCCACAG TCATGATGGG CTCTCTCCTG GCTGCCACCA CTGAGGCCCC TGGTGAATAC 
TTCTTTTCCG ATGGGATCCG GCTAAAGAAA TATCGCGGTA TGGGTTCTCT CGATGCCATG 
GACAAGCACC TCAGCAGCCA GAACAGATAT TTCAGTGAAG CTGACAAAAT CAAAGTGGCC 
CAGGGAGTGT CTGGTGCTGT GCAGGACAAA GGGTCAATCC ACAAATTTGT CCCTTACCTG 
ATTGCTGGCA TCCAACACTC ATGCCAGGAC ATTGGTGCCA AGAGCTTGAC CCAAGTCCGA 
GCCATGATGT ACTCTGGGGA GCTTAAGTTT GAGAAGAGAA CGTCCTCAGC CCAGGTGGAA 
GGTGGCGTCC ATAGCCTCCA TTCGTATGAG AAGCGGCTTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000875.2
CDS	49..1593
Translation	MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF

Target ORF information:

RefSeq Version	NM_000884.3
Organism	Homo sapiens(human)
Definition	Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000884.3

ORF Insert Sequence:

ATGGCCGACT ACCTGATTAG TGGGGGCACG TCCTACGTGC CAGACGACGG ACTCACAGCA 
CAGCAGCTCT TCAACTGCGG AGACGGCCTC ACCTACAATG ACTTTCTCAT TCTCCCTGGG 
TACATCGACT TCACTGCAGA CCAGGTGGAC CTGACTTCTG CTCTGACCAA GAAAATCACT 
CTTAAGACCC CACTGGTTTC CTCTCCCATG GACACAGTCA CAGAGGCTGG GATGGCCATA 
GCAATGGCGC TTACAGGCGG TATTGGCTTC ATCCACCACA ACTGTACACC TGAATTCCAG 
GCCAATGAAG TTCGGAAAGT GAAGAAATAT GAACAGGGAT TCATCACAGA CCCTGTGGTC 
CTCAGCCCCA AGGATCGCGT GCGGGATGTT TTTGAGGCCA AGGCCCGGCA TGGTTTCTGC 
GGTATCCCAA TCACAGACAC AGGCCGGATG GGGAGCCGCT TGGTGGGCAT CATCTCCTCC 
AGGGACATTG ATTTTCTCAA AGAGGAGGAA CATGACTGTT TCTTGGAAGA GATAATGACA 
AAGAGGGAAG ACTTGGTGGT AGCCCCTGCA GGCATCACAC TGAAGGAGGC AAATGAAATT 
CTGCAGCGCA GCAAGAAGGG AAAGTTGCCC ATTGTAAATG AAGATGATGA GCTTGTGGCC 
ATCATTGCCC GGACAGACCT GAAGAAGAAT CGGGACTACC CACTAGCCTC CAAAGATGCC 
AAGAAACAGC TGCTGTGTGG GGCAGCCATT GGCACTCATG AGGATGACAA GTATAGGCTG 
GACTTGCTCG CCCAGGCTGG TGTGGATGTA GTGGTTTTGG ACTCTTCCCA GGGAAATTCC 
ATCTTCCAGA TCAATATGAT CAAGTACATC AAAGACAAAT ACCCTAATCT CCAAGTCATT 
GGAGGCAATG TGGTCACTGC TGCCCAGGCC AAGAACCTCA TTGATGCAGG TGTGGATGCC 
CTGCGGGTGG GCATGGGAAG TGGCTCCATC TGCATTACGC AGGAAGTGCT GGCCTGTGGG 
CGGCCCCAAG CAACAGCAGT GTACAAGGTG TCAGAGTATG CACGGCGCTT TGGTGTTCCG 
GTCATTGCTG ATGGAGGAAT CCAAAATGTG GGTCATATTG CGAAAGCCTT GGCCCTTGGG 
GCCTCCACAG TCATGATGGG CTCTCTCCTG GCTGCCACCA CTGAGGCCCC TGGTGAATAC 
TTCTTTTCCG ATGGGATCCG GCTAAAGAAA TATCGCGGTA TGGGTTCTCT CGATGCCATG 
GACAAGCACC TCAGCAGCCA GAACAGATAT TTCAGTGAAG CTGACAAAAT CAAAGTGGCC 
CAGGGAGTGT CTGGTGCTGT GCAGGACAAA GGGTCAATCC ACAAATTTGT CCCTTACCTG 
ATTGCTGGCA TCCAACACTC ATGCCAGGAC ATTGGTGCCA AGAGCTTGAC CCAAGTCCGA 
GCCATGATGT ACTCTGGGGA GCTTAAGTTT GAGAAGAGAA CGTCCTCAGC CCAGGTGGAA 
GGTGGCGTCC ATAGCCTCCA TTCGTATGAG AAGCGGCTTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IMPDH2 ( XM_006713128.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006713191.1 Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu37205
Clone ID Related Accession (Same CDS sequence)	XM_006713128.3
Accession Version	XM_006713128.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1827bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	inosine-5'-monophosphate dehydrogenase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006713128.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCTATA CGCATGCGCT GTTTCTTCAG CGCCAGCTCC GCCCCCGCCG CAGCGAGGCG 
GGTAGGTTCC GCCCGCGCGC ACTACGCCCT GACGTCAGCG TCGCGCGCAG CGCAGTGACG 
AAATCGGCTG GTTTATATTG GCGCGGCCCA GACGGCAGAG GTCTCTGCGG CGCGGTCCTC 
GGAGACACGC GGCGGTGTCC TGTGTTGGCC ATGGCCGACT ACCTGATTAG TGGGGGCACG 
TCCTACGTGC CAGACGACGG ACTCACAGCA CAGCAGCTCT TCAACTGCGG AGACGGCCTC 
ACCTACAATG ACTTTCTCAT TCTCCCTGGG TACATCGACT TCACTGCAGA CCAGGTGGAC 
CTGACTTCTG CTCTGACCAA GAAAATCACT CTTAAGACCC CACTGGTTTC CTCTCCCATG 
GACACAGTCA CAGAGGCTGG GATGGCCATA GCAATGGCGC TTACAGGCGG TATTGGCTTC 
ATCCACCACA ACTGTACACC TGAATTCCAG GCCAATGAAG TTCGGAAAGT GAAGAAATAT 
GAACAGGGAT TCATCACAGA CCCTGTGGTC CTCAGCCCCA AGGATCGCGT GCGGGATGTT 
TTTGAGGCCA AGGCCCGGCA TGGTTTCTGC GGTATCCCAA TCACAGACAC AGGCCGGATG 
GGGAGCCGCT TGGTGGGCAT CATCTCCTCC AGGGACATTG ATTTTCTCAA AGAGGAGGAA 
CATGACTGTT TCTTGGAAGA GATAATGACA AAGAGGGAAG ACTTGGTGGT AGCCCCTGCA 
GGCATCACAC TGAAGGAGGC AAATGAAATT CTGCAGCGCA GCAAGAAGGG AAAGTTGCCC 
ATTGTAAATG AAGATGATGA GCTTGTGGCC ATCATTGCCC GGACAGACCT GAAGAAGAAT 
CGGGACTACC CACTAGCCTC CAAAGATGCC AAGAAACAGC TGCTGTGTGG GGCAGCCATT 
GGCACTCATG AGGATGACAA GTATAGGCTG GACTTGCTCG CCCAGGCTGG TGTGGATGTA 
GTGGTTTTGG ACTCTTCCCA GGGAAATTCC ATCTTCCAGA TCAATATGAT CAAGTACATC 
AAAGACAAAT ACCCTAATCT CCAAGTCATT GGAGGCAATG TGGTCACTGC TGCCCAGGCC 
AAGAACCTCA TTGATGCAGG TGTGGATGCC CTGCGGGTGG GCATGGGAAG TGGCTCCATC 
TGCATTACGC AGGAAGTGGC TCCCAAGATC CCTCCAGACA TAAAGTCCCA CAGCCCCAAA 
TGCCCTTCTA CTGTCACGGG TTGCTATATG CTGGCCTGTG GGCGGCCCCA AGCAACAGCA 
GTGTACAAGG TGTCAGAGTA TGCACGGCGC TTTGGTGTTC CGGTCATTGC TGATGGAGGA 
ATCCAAAATG TGGGTCATAT TGCGAAAGCC TTGGCCCTTG GGGCCTCCAC AGTCATGATG 
GGCTCTCTCC TGGCTGCCAC CACTGAGGCC CCTGGTGAAT ACTTCTTTTC CGATGGGATC 
CGGCTAAAGA AATATCGCGG TATGGGTTCT CTCGATGCCA TGGACAAGCA CCTCAGCAGC 
CAGAACAGAT ATTTCAGTGA AGCTGACAAA ATCAAAGTGG CCCAGGGAGT GTCTGGTGCT 
GTGCAGGACA AAGGGTCAAT CCACAAATTT GTCCCTTACC TGATTGCTGG CATCCAACAC 
TCATGCCAGG ACATTGGTGC CAAGAGCTTG ACCCAAGTCC GAGCCATGAT GTACTCTGGG 
GAGCTTAAGT TTGAGAAGAG AACGTCCTCA GCCCAGGTGG AAGGTGGCGT CCATAGCCTC 
CATTCGTATG AGAAGCGGCT TTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006713191.1
CDS	191..2017
Translation	MCYTHALFLQRQLRPRRSEAGRFRPRALRPDVSVARSAVTKSAGLYWRGPDGRGLCGAVLGDTRRCPVLAMADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVAPKIPPDIKSHSPKCPSTVTGCYMLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF

Target ORF information:

RefSeq Version	XM_006713128.3
Organism	Homo sapiens(human)
Definition	Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006713128.3

ORF Insert Sequence:

ATGTGCTATA CGCATGCGCT GTTTCTTCAG CGCCAGCTCC GCCCCCGCCG CAGCGAGGCG 
GGTAGGTTCC GCCCGCGCGC ACTACGCCCT GACGTCAGCG TCGCGCGCAG CGCAGTGACG 
AAATCGGCTG GTTTATATTG GCGCGGCCCA GACGGCAGAG GTCTCTGCGG CGCGGTCCTC 
GGAGACACGC GGCGGTGTCC TGTGTTGGCC ATGGCCGACT ACCTGATTAG TGGGGGCACG 
TCCTACGTGC CAGACGACGG ACTCACAGCA CAGCAGCTCT TCAACTGCGG AGACGGCCTC 
ACCTACAATG ACTTTCTCAT TCTCCCTGGG TACATCGACT TCACTGCAGA CCAGGTGGAC 
CTGACTTCTG CTCTGACCAA GAAAATCACT CTTAAGACCC CACTGGTTTC CTCTCCCATG 
GACACAGTCA CAGAGGCTGG GATGGCCATA GCAATGGCGC TTACAGGCGG TATTGGCTTC 
ATCCACCACA ACTGTACACC TGAATTCCAG GCCAATGAAG TTCGGAAAGT GAAGAAATAT 
GAACAGGGAT TCATCACAGA CCCTGTGGTC CTCAGCCCCA AGGATCGCGT GCGGGATGTT 
TTTGAGGCCA AGGCCCGGCA TGGTTTCTGC GGTATCCCAA TCACAGACAC AGGCCGGATG 
GGGAGCCGCT TGGTGGGCAT CATCTCCTCC AGGGACATTG ATTTTCTCAA AGAGGAGGAA 
CATGACTGTT TCTTGGAAGA GATAATGACA AAGAGGGAAG ACTTGGTGGT AGCCCCTGCA 
GGCATCACAC TGAAGGAGGC AAATGAAATT CTGCAGCGCA GCAAGAAGGG AAAGTTGCCC 
ATTGTAAATG AAGATGATGA GCTTGTGGCC ATCATTGCCC GGACAGACCT GAAGAAGAAT 
CGGGACTACC CACTAGCCTC CAAAGATGCC AAGAAACAGC TGCTGTGTGG GGCAGCCATT 
GGCACTCATG AGGATGACAA GTATAGGCTG GACTTGCTCG CCCAGGCTGG TGTGGATGTA 
GTGGTTTTGG ACTCTTCCCA GGGAAATTCC ATCTTCCAGA TCAATATGAT CAAGTACATC 
AAAGACAAAT ACCCTAATCT CCAAGTCATT GGAGGCAATG TGGTCACTGC TGCCCAGGCC 
AAGAACCTCA TTGATGCAGG TGTGGATGCC CTGCGGGTGG GCATGGGAAG TGGCTCCATC 
TGCATTACGC AGGAAGTGGC TCCCAAGATC CCTCCAGACA TAAAGTCCCA CAGCCCCAAA 
TGCCCTTCTA CTGTCACGGG TTGCTATATG CTGGCCTGTG GGCGGCCCCA AGCAACAGCA 
GTGTACAAGG TGTCAGAGTA TGCACGGCGC TTTGGTGTTC CGGTCATTGC TGATGGAGGA 
ATCCAAAATG TGGGTCATAT TGCGAAAGCC TTGGCCCTTG GGGCCTCCAC AGTCATGATG 
GGCTCTCTCC TGGCTGCCAC CACTGAGGCC CCTGGTGAAT ACTTCTTTTC CGATGGGATC 
CGGCTAAAGA AATATCGCGG TATGGGTTCT CTCGATGCCA TGGACAAGCA CCTCAGCAGC 
CAGAACAGAT ATTTCAGTGA AGCTGACAAA ATCAAAGTGG CCCAGGGAGT GTCTGGTGCT 
GTGCAGGACA AAGGGTCAAT CCACAAATTT GTCCCTTACC TGATTGCTGG CATCCAACAC 
TCATGCCAGG ACATTGGTGC CAAGAGCTTG ACCCAAGTCC GAGCCATGAT GTACTCTGGG 
GAGCTTAAGT TTGAGAAGAG AACGTCCTCA GCCCAGGTGG AAGGTGGCGT CCATAGCCTC 
CATTCGTATG AGAAGCGGCT TTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IMPDH2 ( XM_017006349.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016861838.1 Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), transcript variant X2, mRNA.

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CloneID	OHu94152
Clone ID Related Accession (Same CDS sequence)	XM_017006349.1
Accession Version	XM_017006349.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1752bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	inosine-5'-monophosphate dehydrogenase 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCTATA CGCATGCGCT GTTTCTTCAG CGCCAGCTCC GCCCCCGCCG CAGCGAGGCG 
GGTAGGTTCC GCCCGCGCGC ACTACGCCCT GACGTCAGCG TCGCGCGCAG CGCAGTGACG 
AAATCGGCTG GTTTATATTG GCGCGGCCCA GACGGCAGAG GTCTCTGCGG CGCGGTCCTC 
GGAGACACGC GGCGGTGTCC TGTGTTGGCC ATGGCCGACT ACCTGATTAG TGGGGGCACG 
TCCTACGTGC CAGACGACGG ACTCACAGCA CAGCAGCTCT TCAACTGCGG AGACGGCCTC 
ACCTACAATG ACTTTCTCAT TCTCCCTGGG TACATCGACT TCACTGCAGA CCAGGTGGAC 
CTGACTTCTG CTCTGACCAA GAAAATCACT CTTAAGACCC CACTGGTTTC CTCTCCCATG 
GACACAGTCA CAGAGGCTGG GATGGCCATA GCAATGGCGA AATATGAACA GGGATTCATC 
ACAGACCCTG TGGTCCTCAG CCCCAAGGAT CGCGTGCGGG ATGTTTTTGA GGCCAAGGCC 
CGGCATGGTT TCTGCGGTAT CCCAATCACA GACACAGGCC GGATGGGGAG CCGCTTGGTG 
GGCATCATCT CCTCCAGGGA CATTGATTTT CTCAAAGAGG AGGAACATGA CTGTTTCTTG 
GAAGAGATAA TGACAAAGAG GGAAGACTTG GTGGTAGCCC CTGCAGGCAT CACACTGAAG 
GAGGCAAATG AAATTCTGCA GCGCAGCAAG AAGGGAAAGT TGCCCATTGT AAATGAAGAT 
GATGAGCTTG TGGCCATCAT TGCCCGGACA GACCTGAAGA AGAATCGGGA CTACCCACTA 
GCCTCCAAAG ATGCCAAGAA ACAGCTGCTG TGTGGGGCAG CCATTGGCAC TCATGAGGAT 
GACAAGTATA GGCTGGACTT GCTCGCCCAG GCTGGTGTGG ATGTAGTGGT TTTGGACTCT 
TCCCAGGGAA ATTCCATCTT CCAGATCAAT ATGATCAAGT ACATCAAAGA CAAATACCCT 
AATCTCCAAG TCATTGGAGG CAATGTGGTC ACTGCTGCCC AGGCCAAGAA CCTCATTGAT 
GCAGGTGTGG ATGCCCTGCG GGTGGGCATG GGAAGTGGCT CCATCTGCAT TACGCAGGAA 
GTGGCTCCCA AGATCCCTCC AGACATAAAG TCCCACAGCC CCAAATGCCC TTCTACTGTC 
ACGGGTTGCT ATATGCTGGC CTGTGGGCGG CCCCAAGCAA CAGCAGTGTA CAAGGTGTCA 
GAGTATGCAC GGCGCTTTGG TGTTCCGGTC ATTGCTGATG GAGGAATCCA AAATGTGGGT 
CATATTGCGA AAGCCTTGGC CCTTGGGGCC TCCACAGTCA TGATGGGCTC TCTCCTGGCT 
GCCACCACTG AGGCCCCTGG TGAATACTTC TTTTCCGATG GGATCCGGCT AAAGAAATAT 
CGCGGTATGG GTTCTCTCGA TGCCATGGAC AAGCACCTCA GCAGCCAGAA CAGATATTTC 
AGTGAAGCTG ACAAAATCAA AGTGGCCCAG GGAGTGTCTG GTGCTGTGCA GGACAAAGGG 
TCAATCCACA AATTTGTCCC TTACCTGATT GCTGGCATCC AACACTCATG CCAGGACATT 
GGTGCCAAGA GCTTGACCCA AGTCCGAGCC ATGATGTACT CTGGGGAGCT TAAGTTTGAG 
AAGAGAACGT CCTCAGCCCA GGTGGAAGGT GGCGTCCATA GCCTCCATTC GTATGAGAAG 
CGGCTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016861838.1
CDS	143..1894
Translation	MCYTHALFLQRQLRPRRSEAGRFRPRALRPDVSVARSAVTKSAGLYWRGPDGRGLCGAVLGDTRRCPVLAMADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMAKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVAPKIPPDIKSHSPKCPSTVTGCYMLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF

Target ORF information:

RefSeq Version	XM_017006349.1
Organism	Homo sapiens(human)
Definition	Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006349.1

ORF Insert Sequence:

ATGTGCTATA CGCATGCGCT GTTTCTTCAG CGCCAGCTCC GCCCCCGCCG CAGCGAGGCG 
GGTAGGTTCC GCCCGCGCGC ACTACGCCCT GACGTCAGCG TCGCGCGCAG CGCAGTGACG 
AAATCGGCTG GTTTATATTG GCGCGGCCCA GACGGCAGAG GTCTCTGCGG CGCGGTCCTC 
GGAGACACGC GGCGGTGTCC TGTGTTGGCC ATGGCCGACT ACCTGATTAG TGGGGGCACG 
TCCTACGTGC CAGACGACGG ACTCACAGCA CAGCAGCTCT TCAACTGCGG AGACGGCCTC 
ACCTACAATG ACTTTCTCAT TCTCCCTGGG TACATCGACT TCACTGCAGA CCAGGTGGAC 
CTGACTTCTG CTCTGACCAA GAAAATCACT CTTAAGACCC CACTGGTTTC CTCTCCCATG 
GACACAGTCA CAGAGGCTGG GATGGCCATA GCAATGGCGA AATATGAACA GGGATTCATC 
ACAGACCCTG TGGTCCTCAG CCCCAAGGAT CGCGTGCGGG ATGTTTTTGA GGCCAAGGCC 
CGGCATGGTT TCTGCGGTAT CCCAATCACA GACACAGGCC GGATGGGGAG CCGCTTGGTG 
GGCATCATCT CCTCCAGGGA CATTGATTTT CTCAAAGAGG AGGAACATGA CTGTTTCTTG 
GAAGAGATAA TGACAAAGAG GGAAGACTTG GTGGTAGCCC CTGCAGGCAT CACACTGAAG 
GAGGCAAATG AAATTCTGCA GCGCAGCAAG AAGGGAAAGT TGCCCATTGT AAATGAAGAT 
GATGAGCTTG TGGCCATCAT TGCCCGGACA GACCTGAAGA AGAATCGGGA CTACCCACTA 
GCCTCCAAAG ATGCCAAGAA ACAGCTGCTG TGTGGGGCAG CCATTGGCAC TCATGAGGAT 
GACAAGTATA GGCTGGACTT GCTCGCCCAG GCTGGTGTGG ATGTAGTGGT TTTGGACTCT 
TCCCAGGGAA ATTCCATCTT CCAGATCAAT ATGATCAAGT ACATCAAAGA CAAATACCCT 
AATCTCCAAG TCATTGGAGG CAATGTGGTC ACTGCTGCCC AGGCCAAGAA CCTCATTGAT 
GCAGGTGTGG ATGCCCTGCG GGTGGGCATG GGAAGTGGCT CCATCTGCAT TACGCAGGAA 
GTGGCTCCCA AGATCCCTCC AGACATAAAG TCCCACAGCC CCAAATGCCC TTCTACTGTC 
ACGGGTTGCT ATATGCTGGC CTGTGGGCGG CCCCAAGCAA CAGCAGTGTA CAAGGTGTCA 
GAGTATGCAC GGCGCTTTGG TGTTCCGGTC ATTGCTGATG GAGGAATCCA AAATGTGGGT 
CATATTGCGA AAGCCTTGGC CCTTGGGGCC TCCACAGTCA TGATGGGCTC TCTCCTGGCT 
GCCACCACTG AGGCCCCTGG TGAATACTTC TTTTCCGATG GGATCCGGCT AAAGAAATAT 
CGCGGTATGG GTTCTCTCGA TGCCATGGAC AAGCACCTCA GCAGCCAGAA CAGATATTTC 
AGTGAAGCTG ACAAAATCAA AGTGGCCCAG GGAGTGTCTG GTGCTGTGCA GGACAAAGGG 
TCAATCCACA AATTTGTCCC TTACCTGATT GCTGGCATCC AACACTCATG CCAGGACATT 
GGTGCCAAGA GCTTGACCCA AGTCCGAGCC ATGATGTACT CTGGGGAGCT TAAGTTTGAG 
AAGAGAACGT CCTCAGCCCA GGTGGAAGGT GGCGTCCATA GCCTCCATTC GTATGAGAAG 
CGGCTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IMPDH2 ( XM_017006350.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016861839.1 Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu94153
Clone ID Related Accession (Same CDS sequence)	XM_017006350.1
Accession Version	XM_017006350.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	inosine-5'-monophosphate dehydrogenase 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCTATA CGCATGCGCT GTTTCTTCAG CGCCAGCTCC GCCCCCGCCG CAGCGAGGCG 
GGTAGGTTCC GCCCGCGCGC ACTACGCCCT GACGTCAGCG TCGCGCGCAG CGCAGTGACG 
AAATCGGCTG GTTTATATTG GCGCGGCCCA GACGGCAGAG GTCTCTGCGG CGCGGTCCTC 
GGAGACACGC GGCGGTGTCC TGTGTTGGCC ATGGCCGACT ACCTGATTAG TGGGGGCACG 
TCCTACGTGC CAGACGACGG ACTCACAGCA CAGCAGCTCT TCAACTGCGG AGACGGCCTC 
ACCTACAATG ACTTTCTCAT TCTCCCTGGG TACATCGACT TCACTGCAGA CCAGGTGGAC 
CTGACTTCTG CTCTGACCAA GAAAATCACT CTTAAGACCC CACTGGTTTC CTCTCCCATG 
GACACAGTCA CAGAGGCTGG GATGGCCATA GCAATGGCGA AATATGAACA GGGATTCATC 
ACAGACCCTG TGGTCCTCAG CCCCAAGGAT CGCGTGCGGG ATGTTTTTGA GGCCAAGGCC 
CGGCATGGTT TCTGCGGTAT CCCAATCACA GACACAGGCC GGATGGGGAG CCGCTTGGTG 
GGCATCATCT CCTCCAGGGA CATTGATTTT CTCAAAGAGG AGGAACATGA CTGTTTCTTG 
GAAGAGATAA TGACAAAGAG GGAAGACTTG GTGGTAGCCC CTGCAGGCAT CACACTGAAG 
GAGGCAAATG AAATTCTGCA GCGCAGCAAG AAGGGAAAGT TGCCCATTGT AAATGAAGAT 
GATGAGCTTG TGGCCATCAT TGCCCGGACA GACCTGAAGA AGAATCGGGA CTACCCACTA 
GCCTCCAAAG ATGCCAAGAA ACAGCTGCTG TGTGGGGCAG CCATTGGCAC TCATGAGGAT 
GACAAGTATA GGCTGGACTT GCTCGCCCAG GCTGGTGTGG ATGTAGTGGT TTTGGACTCT 
TCCCAGGGAA ATTCCATCTT CCAGATCAAT ATGATCAAGT ACATCAAAGA CAAATACCCT 
AATCTCCAAG TCATTGGAGG CAATGTGGTC ACTGCTGCCC AGGCCAAGAA CCTCATTGAT 
GCAGGTGTGG ATGCCCTGCG GGTGGGCATG GGAAGTGGCT CCATCTGCAT TACGCAGGAA 
GTGCTGGCCT GTGGGCGGCC CCAAGCAACA GCAGTGTACA AGGTGTCAGA GTATGCACGG 
CGCTTTGGTG TTCCGGTCAT TGCTGATGGA GGAATCCAAA ATGTGGGTCA TATTGCGAAA 
GCCTTGGCCC TTGGGGCCTC CACAGTCATG ATGGGCTCTC TCCTGGCTGC CACCACTGAG 
GCCCCTGGTG AATACTTCTT TTCCGATGGG ATCCGGCTAA AGAAATATCG CGGTATGGGT 
TCTCTCGATG CCATGGACAA GCACCTCAGC AGCCAGAACA GATATTTCAG TGAAGCTGAC 
AAAATCAAAG TGGCCCAGGG AGTGTCTGGT GCTGTGCAGG ACAAAGGGTC AATCCACAAA 
TTTGTCCCTT ACCTGATTGC TGGCATCCAA CACTCATGCC AGGACATTGG TGCCAAGAGC 
TTGACCCAAG TCCGAGCCAT GATGTACTCT GGGGAGCTTA AGTTTGAGAA GAGAACGTCC 
TCAGCCCAGG TGGAAGGTGG CGTCCATAGC CTCCATTCGT ATGAGAAGCG GCTTTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016861839.1
CDS	143..1822
Translation	MCYTHALFLQRQLRPRRSEAGRFRPRALRPDVSVARSAVTKSAGLYWRGPDGRGLCGAVLGDTRRCPVLAMADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMAKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF

Target ORF information:

RefSeq Version	XM_017006350.1
Organism	Homo sapiens(human)
Definition	Homo sapiens inosine monophosphate dehydrogenase 2 (IMPDH2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006350.1

ORF Insert Sequence:

ATGTGCTATA CGCATGCGCT GTTTCTTCAG CGCCAGCTCC GCCCCCGCCG CAGCGAGGCG 
GGTAGGTTCC GCCCGCGCGC ACTACGCCCT GACGTCAGCG TCGCGCGCAG CGCAGTGACG 
AAATCGGCTG GTTTATATTG GCGCGGCCCA GACGGCAGAG GTCTCTGCGG CGCGGTCCTC 
GGAGACACGC GGCGGTGTCC TGTGTTGGCC ATGGCCGACT ACCTGATTAG TGGGGGCACG 
TCCTACGTGC CAGACGACGG ACTCACAGCA CAGCAGCTCT TCAACTGCGG AGACGGCCTC 
ACCTACAATG ACTTTCTCAT TCTCCCTGGG TACATCGACT TCACTGCAGA CCAGGTGGAC 
CTGACTTCTG CTCTGACCAA GAAAATCACT CTTAAGACCC CACTGGTTTC CTCTCCCATG 
GACACAGTCA CAGAGGCTGG GATGGCCATA GCAATGGCGA AATATGAACA GGGATTCATC 
ACAGACCCTG TGGTCCTCAG CCCCAAGGAT CGCGTGCGGG ATGTTTTTGA GGCCAAGGCC 
CGGCATGGTT TCTGCGGTAT CCCAATCACA GACACAGGCC GGATGGGGAG CCGCTTGGTG 
GGCATCATCT CCTCCAGGGA CATTGATTTT CTCAAAGAGG AGGAACATGA CTGTTTCTTG 
GAAGAGATAA TGACAAAGAG GGAAGACTTG GTGGTAGCCC CTGCAGGCAT CACACTGAAG 
GAGGCAAATG AAATTCTGCA GCGCAGCAAG AAGGGAAAGT TGCCCATTGT AAATGAAGAT 
GATGAGCTTG TGGCCATCAT TGCCCGGACA GACCTGAAGA AGAATCGGGA CTACCCACTA 
GCCTCCAAAG ATGCCAAGAA ACAGCTGCTG TGTGGGGCAG CCATTGGCAC TCATGAGGAT 
GACAAGTATA GGCTGGACTT GCTCGCCCAG GCTGGTGTGG ATGTAGTGGT TTTGGACTCT 
TCCCAGGGAA ATTCCATCTT CCAGATCAAT ATGATCAAGT ACATCAAAGA CAAATACCCT 
AATCTCCAAG TCATTGGAGG CAATGTGGTC ACTGCTGCCC AGGCCAAGAA CCTCATTGAT 
GCAGGTGTGG ATGCCCTGCG GGTGGGCATG GGAAGTGGCT CCATCTGCAT TACGCAGGAA 
GTGCTGGCCT GTGGGCGGCC CCAAGCAACA GCAGTGTACA AGGTGTCAGA GTATGCACGG 
CGCTTTGGTG TTCCGGTCAT TGCTGATGGA GGAATCCAAA ATGTGGGTCA TATTGCGAAA 
GCCTTGGCCC TTGGGGCCTC CACAGTCATG ATGGGCTCTC TCCTGGCTGC CACCACTGAG 
GCCCCTGGTG AATACTTCTT TTCCGATGGG ATCCGGCTAA AGAAATATCG CGGTATGGGT 
TCTCTCGATG CCATGGACAA GCACCTCAGC AGCCAGAACA GATATTTCAG TGAAGCTGAC 
AAAATCAAAG TGGCCCAGGG AGTGTCTGGT GCTGTGCAGG ACAAAGGGTC AATCCACAAA 
TTTGTCCCTT ACCTGATTGC TGGCATCCAA CACTCATGCC AGGACATTGG TGCCAAGAGC 
TTGACCCAAG TCCGAGCCAT GATGTACTCT GGGGAGCTTA AGTTTGAGAA GAGAACGTCC 
TCAGCCCAGG TGGAAGGTGG CGTCCATAGC CTCCATTCGT ATGAGAAGCG GCTTTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis.
Molecular cell68(1)198-209.e6(2017 Oct)
Lin R,Mo Y,Zha H,Qu Z,Xie P,Zhu ZJ,Xu Y,Xiong Y,Guan KL

High expression of IMPDH2 is associated with aggressive features and poor prognosis of primary nasopharyngeal carcinoma.
Scientific reports7(1)745(2017 Apr)
Xu Y,Zheng Z,Gao Y,Duan S,Chen C,Rong J,Wang K,Yun M,Weng H,Ye S,Zhang J

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IMPDH2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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