The following FGD5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FGD5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu06830 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_152536.3 , NM_152536.4 | |
| Accession Version | NM_152536.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4389bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-06-16 | |
| Organism | Homo sapiens(human) | |
| Product | FYVE, RhoGEF and PH domain-containing protein 5 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC087591.2 and AC090937.2. On Jul 10, 2008 this sequence version replaced NM_152536.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK131078.1, BC132816.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGTTCAGGG GTCCGAAGCC CCCCATTGCC CCCAAGCCCA GGCTGACTGC CCCAAACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_689749.3 |
| CDS | 111..4499 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_152536.3 |
1 | ATGTTCAGGG GTCCGAAGCC CCCCATTGCC CCCAAGCCCA GGCTGACTGC CCCAAACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu06830 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_152536.3 , NM_152536.4 | |
| Accession Version | NM_152536.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4389bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-11-18 | |
| Organism | Homo sapiens(human) | |
| Product | FYVE, RhoGEF and PH domain-containing protein 5 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC087591.2 and AC090937.2. On May 17, 2019 this sequence version replaced NM_152536.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC132816.1, AK131078.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000285046.10/ ENSP00000285046.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGTTCAGGG GTCCGAAGCC CCCCATTGCC CCCAAGCCCA GGCTGACTGC CCCAAACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_689749.3 |
| CDS | 111..4499 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_152536.4 |
1 | ATGTTCAGGG GTCCGAAGCC CCCCATTGCC CCCAAGCCCA GGCTGACTGC CCCAAACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu76722 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001320276.1 | |
| Accession Version | NM_001320276.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4260bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-11-16 | |
| Organism | Homo sapiens(human) | |
| Product | FYVE, RhoGEF and PH domain-containing protein 5 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB293373.1, BC144300.1, AC090937.2 and AW589887.1. On Feb 18, 2016 this sequence version replaced XM_011533424.1. Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC144300.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGTTCAGGG GTCCGAAGCC CCCCATTGCC CCCAAGCCCA GGCTGACTGC CCCAAACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001307205.1 |
| CDS | 111..4370 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001320276.1 |
1 | ATGTTCAGGG GTCCGAAGCC CCCCATTGCC CCCAAGCCCA GGCTGACTGC CCCAAACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu76720 | |
| Clone ID Related Accession (Same CDS sequence) | XM_011533422.1 | |
| Accession Version | XM_011533422.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4395bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-05 | |
| Organism | Homo sapiens(human) | |
| Product | FYVE, RhoGEF and PH domain-containing protein 5 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTTCAGGG GTCCGAAGCC CCCCATTGCC CCCAAGCCCA GGCTGACTGC CCCAAACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011531724.1 |
| CDS | 111..4505 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_011533422.1 |
1 | ATGTTCAGGG GTCCGAAGCC CCCCATTGCC CCCAAGCCCA GGCTGACTGC CCCAAACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu76721 | |
| Clone ID Related Accession (Same CDS sequence) | XM_011533423.1 | |
| Accession Version | XM_011533423.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4266bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-05 | |
| Organism | Homo sapiens(human) | |
| Product | FYVE, RhoGEF and PH domain-containing protein 5 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTTCAGGG GTCCGAAGCC CCCCATTGCC CCCAAGCCCA GGCTGACTGC CCCAAACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011531725.1 |
| CDS | 111..4376 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_011533423.1 |
1 | ATGTTCAGGG GTCCGAAGCC CCCCATTGCC CCCAAGCCCA GGCTGACTGC CCCAAACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
FGD5 Regulates VEGF Receptor-2 Coupling to PI3 Kinase and Receptor Recycling. |
FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation. |
FGD5 amplification in breast cancer patients is associated with tumour proliferation and a poorer prognosis. |
