tlx3b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	tlx3b
Entrez Gene ID	266965
Full Name	T cell leukemia homeobox 3b
Synonyms	Tlx-3b,ztlx-3b
General protein information	Preferred Names T cell leukemia homeobox 3b Names T-cell leukemia homeobox protein 3 tlx3
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_170766.1	NP_739572.1	T-cell leukemia homeobox protein 3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TLX3	XP_546241.3
Bos taurus (cattle)	TLX3	NP_001180120.1
Xenopus tropicalis (tropical clawed frog)	tlx3	NP_001015902.1
	TLX3	XP_001095250.1
Danio rerio (zebrafish)	tlx3b	NP_739572.1
Mus musculus (house mouse)	Tlx3	NP_064300.2
Homo sapiens (human)	TLX3	NP_066305.2
Rattus norvegicus (Norway rat)	Tlx3	XP_573065.3

Gene Ontology
Bibliography

Related articles in PubMed

Dlx3b/4b is required for early-born but not later-forming sensory hair cells during zebrafish inner ear development.
Schwarzer S, Spie? S, Brand M, Hans S
Biology open6(9)1270-1278(2017 Sep)

Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum.
Takeuchi M, Yamaguchi S, Sakakibara Y, Hayashi T, Matsuda K, Hara Y, Tanegashima C, Shimizu T, Kuraku S, Hibi M
The Journal of comparative neurology525(7)1558-1585(2017 May)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Identification of possible downstream genes required for the extension of peripheral axons in primary sensory neurons.
Aoki M, Segawa H, Naito M, Okamoto H
Biochemical and biophysical research communications445(2)357-62(2014 Mar)

Several cis-regulatory elements control mRNA stability, translation efficiency, and expression pattern of Prrxl1 (paired related homeobox protein-like 1).
Regadas I, Matos MR, Monteiro FA, G?mez-Skarmeta JL, Lima D, Bessa J, Casares F, Reguenga C
The Journal of biological chemistry288(51)36285-301(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

identification and expression patterns of three members of the zebrafish Tlx family
Title: Molecular cloning and developmental expression of Tlx (Hox11) genes in zebrafish (Danio rerio).

The following tlx3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the tlx3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa00988	NM_170766.1 Latest version!	Danio rerio T cell leukemia homeobox 3b (tlx3b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

tlx3b ( NM_170766.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_739572.1 Danio rerio T cell leukemia homeobox 3b (tlx3b), mRNA.

Price & Availability↑

CloneID	ODa00988
Clone ID Related Accession (Same CDS sequence)	NM_170766.1
Accession Version	NM_170766.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-02-18
Organism	Danio rerio(zebrafish)
Product	T-cell leukemia homeobox protein 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF398519.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF398519.1, BC162310.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898401, SAMEA898403 [ECO:0000348] ##Evidence-Data-END##

ATGGACCGAG CTCCAAGCTC CAGCCCAAGT GGCACCAGTC AAACATCACA ACCAACCCAA 
CATGAACCCA TCAGCTTCGG CATTGACCAG ATTCTCAGCG GAACCGATCA AGAATCACAG 
CAGAACTCGA CCAGGAATAG TTCGGAGAGC AGCAGTGGCA GTAGCAGTGC GAGCGGAGGC 
TGTTACCATC TCGGCAGCCC AACGGGAGCG AGCGCAACGC CGTACACGAC GCTTACCGGC 
ACATTTCATG GTATCGCGGC TCCTTATGAG GAGTCCAGTC CATACGGAGT GAACTTGACC 
CTTGCGCCCG GAGGAGTGAT TAGGGTCCCG GCGCACAGGC CCCTTGCCGC GGCCGTTCCT 
CCACCTATGG CCAGCGCGGT ACCCGGACTT GGGAGCCTCA GTTTTCCCTG GATGGAGAGC 
AGCCAGCGCT TTGCAAAAGA CAGGTTTGCA GCAGCCTTGA CGCCTTTTAC TGTGGCTCGG 
CGTATTGGTC ACCCGTACCA GAACCGCACA CCACCAAAGA GAAAGAAGCC TCGCACGTCC 
TTCTCCAGAG TGCAGATCTG TGAGCTGGAG AAGCGCTTCC ACAGACAGAA ATACCTGGCC 
AGCGCTGAAC GGGCAGCTTT GGCCAAAACT CTAAAGATGA CAGACGCACA GGTCAAAACA 
TGGTTTCAGA ACCGCAGGAC TAAATGGAGA AGGCAAACGG CGGAGGAAAG GGAAGCAGAG 
CGTCAGCAGG CCAACCGGCT AATGATTCAG CTTCAGCATG ATGCCTTCCA GAAATCTTTG 
ACTGATTCAG TTCCAACAGA TCCGCTCTGC ATCCACAACT CATCCCTGTT TGCCCTGCAG 
AACCTACAGC CTTGGGCTAG TGAAGAGAGC AGCAAGCTTG GAGGAGTGAC GGCGCTCGTA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_739572.1
CDS	80..982
Translation	MDRAPSSSPSGTSQTSQPTQHEPISFGIDQILSGTDQESQQNSTRNSSESSSGSSSASGGCYHLGSPTGASATPYTTLTGTFHGIAAPYEESSPYGVNLTLAPGGVIRVPAHRPLAAAVPPPMASAVPGLGSLSFPWMESSQRFAKDRFAAALTPFTVARRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKTLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRLMIQLQHDAFQKSLTDSVPTDPLCIHNSSLFALQNLQPWASEESSKLGGVTALV

Target ORF information:

RefSeq Version	NM_170766.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio T cell leukemia homeobox 3b (tlx3b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_170766.1

ORF Insert Sequence:

ATGGACCGAG CTCCAAGCTC CAGCCCAAGT GGCACCAGTC AAACATCACA ACCAACCCAA 
CATGAACCCA TCAGCTTCGG CATTGACCAG ATTCTCAGCG GAACCGATCA AGAATCACAG 
CAGAACTCGA CCAGGAATAG TTCGGAGAGC AGCAGTGGCA GTAGCAGTGC GAGCGGAGGC 
TGTTACCATC TCGGCAGCCC AACGGGAGCG AGCGCAACGC CGTACACGAC GCTTACCGGC 
ACATTTCATG GTATCGCGGC TCCTTATGAG GAGTCCAGTC CATACGGAGT GAACTTGACC 
CTTGCGCCCG GAGGAGTGAT TAGGGTCCCG GCGCACAGGC CCCTTGCCGC GGCCGTTCCT 
CCACCTATGG CCAGCGCGGT ACCCGGACTT GGGAGCCTCA GTTTTCCCTG GATGGAGAGC 
AGCCAGCGCT TTGCAAAAGA CAGGTTTGCA GCAGCCTTGA CGCCTTTTAC TGTGGCTCGG 
CGTATTGGTC ACCCGTACCA GAACCGCACA CCACCAAAGA GAAAGAAGCC TCGCACGTCC 
TTCTCCAGAG TGCAGATCTG TGAGCTGGAG AAGCGCTTCC ACAGACAGAA ATACCTGGCC 
AGCGCTGAAC GGGCAGCTTT GGCCAAAACT CTAAAGATGA CAGACGCACA GGTCAAAACA 
TGGTTTCAGA ACCGCAGGAC TAAATGGAGA AGGCAAACGG CGGAGGAAAG GGAAGCAGAG 
CGTCAGCAGG CCAACCGGCT AATGATTCAG CTTCAGCATG ATGCCTTCCA GAAATCTTTG 
ACTGATTCAG TTCCAACAGA TCCGCTCTGC ATCCACAACT CATCCCTGTT TGCCCTGCAG 
AACCTACAGC CTTGGGCTAG TGAAGAGAGC AGCAAGCTTG GAGGAGTGAC GGCGCTCGTA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dlx3b/4b is required for early-born but not later-forming sensory hair cells during zebrafish inner ear development.
Biology open6(9)1270-1278(2017 Sep)
Schwarzer S,Spie? S,Brand M,Hans S

Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum.
The Journal of comparative neurology525(7)1558-1585(2017 May)
Takeuchi M,Yamaguchi S,Sakakibara Y,Hayashi T,Matsuda K,Hara Y,Tanegashima C,Shimizu T,Kuraku S,Hibi M

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Identification of possible downstream genes required for the extension of peripheral axons in primary sensory neurons.
Biochemical and biophysical research communications445(2)357-62(2014 Mar)
Aoki M,Segawa H,Naito M,Okamoto H

Several cis-regulatory elements control mRNA stability, translation efficiency, and expression pattern of Prrxl1 (paired related homeobox protein-like 1).
The Journal of biological chemistry288(51)36285-301(2013 Dec)
Regadas I,Matos MR,Monteiro FA,G?mez-Skarmeta JL,Lima D,Bessa J,Casares F,Reguenga C