SDS-Page
Endotoxin
qPCR
30+ AAV 血清型
様々な特殊バリエーションに対応可能
100%精度
AAV ITR保証型QC利用可能
≥1E+13 GC/mL 保証型納品
純度 >95%
フルカプシド率 >70%
| AAVグレード | ボリューム | 保証型納品 | デフォルトQC | QCオプション | 応用 |
|---|---|---|---|---|---|
| HT Grade | 1 mL |
|
|
|
In Vitro |
| 2.5 mL | |||||
| 5 mL | |||||
| Research Grade | 0.2 mL |
|
|
In Vivo & In Vitro | |
| 0.5 mL | |||||
| 1 mL | |||||
| 2 mL | |||||
| Customized Volume |
SDS-PAGE analysis of different AAV serotypes with silver staining
(Purified virions were achieved by chromatography)
Empty / Full Ratio
Titer: 1x1012-13 gc/ml (qPCR)
| Characteristic | AAV | Retrovirus | Lentivirus |
|---|---|---|---|
| Genome | 4.8kb(ssDNA) | 9.7kb (ssRNA) | 9kb (ssRNA) |
| Packaging Capacity | 4.7kb | 3kb | 9kb |
| Infection | Most dividing and non-dividing cells | Only infect mitotically active cells | Most dividing and non-dividing cells |
| Transduction Efficiency | Moderate | High | Moderate |
| Integration | Non-integrating | Integrating | Integrating |
| Expression | Transient or stable | Stable | Stable or Transient |
| Immunogenicity | Very Low | High | Low |
| Biosafety | BSL-1 | BSL-2 | BSL-2 |
| Gene Therapy Strategy | In vivo & In vitro | Ex vivo | In vitro & Ex vivo |
| Tissue type | Recommended AAV Serotype |
|---|---|
| Central Nervous System (CNS) | AAV1, AAV5, AAV8, AAV9, AAV-DJ |
| Heart | AAV1, AAV8, AAV9 |
| Kidney | AAV2, AAV9 |
| Liver | AAV8, AAV9, AAV-DJ |
| Lung | AAV5, AAV6, AAV9 |
| Pancreas | AAV8 |
| RPE (Retinal Pigment Epithelium) | AAV1, AAV2, AAV5, AAV8 |
| Skeletal Muscle | AAV1, AAV6, AAV8, AAV9 |
Our customer service representatives are available 24 hours Monday through Friday. You may contact us anytime for assistance. Orders can be placed online, over the phone, by email or fax. Please have your payment information (credit card, purchase order or bank information) ready.
