tlx3 cDNA ORF clone, Xenopus tropicalis(tropical clawed frog)

Gene
Clones
gRNAs

Summary

Gene Symbol	tlx3
Entrez Gene ID	548656
Full Name	T cell leukemia homeobox 3
Synonyms	XHox11L2,hox11l2,rnx
General protein information	Preferred Names T cell leukemia homeobox 3 Names T-cell leukemia homeobox protein 3
Gene Type	protein-coding
Organism	Xenopus tropicalis(tropical clawed frog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001015902.2	NP_001015902.1	T-cell leukemia homeobox protein 3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TLX3	XP_546241.3
Bos taurus (cattle)	TLX3	NP_001180120.1
Xenopus tropicalis (tropical clawed frog)	tlx3	NP_001015902.1
	TLX3	XP_001095250.1
Danio rerio (zebrafish)	tlx3b	NP_739572.1
Mus musculus (house mouse)	Tlx3	NP_064300.2
Homo sapiens (human)	TLX3	NP_066305.2
Rattus norvegicus (Norway rat)	Tlx3	XP_573065.3

Gene Ontology
Bibliography

Related articles in PubMed

cJun integrates calcium activity and tlx3 expression to regulate neurotransmitter specification.
Marek KW, Kurtz LM, Spitzer NC
Nature neuroscience13(8)944-50(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The cJun transcription factor bound to a variant cAMP response element in the promoter region of tlx3 and modulated transcription and regulated neurotransmitter phenotype via its transactivation domain
Title: cJun integrates calcium activity and tlx3 expression to regulate neurotransmitter specification.

The following tlx3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the tlx3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OXa22336	NM_001015902.2 Latest version!	Xenopus tropicalis T cell leukemia homeobox 3 (tlx3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

tlx3 ( NM_001015902.2 ) cDNA ORF clone, Xenopus tropicalis(tropical clawed frog) -> NP_001015902.1 Xenopus tropicalis T cell leukemia homeobox 3 (tlx3), mRNA.

Price & Availability↑

CloneID	OXa22336
Clone ID Related Accession (Same CDS sequence)	NM_001015902.2
Accession Version	NM_001015902.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Xenopus tropicalis(tropical clawed frog)
Product	T-cell leukemia homeobox protein 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CR926440.2. On Oct 14, 2005 this sequence version replaced NM_001015902.1. ##Evidence-Data-START## Transcript exon combination :: CR926440.2, BX705785.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00861989, SAMN00861990 [ECO:0000348] ##Evidence-Data-END##

ATGGATCAGC CAACAAGTGC GCAGACCCAG CACCAACACG AACCCATCAG TTTCGGGATT 
GATCAGATAT TAAGCAGTTC CGATCAGGAA AACTCTTCCC AGTCGTCGGC CGCCGCCGCT 
GTCCGGGGCT CGGAGGGCAG TTACCTGGGG AGCCCAGTGA GTCGCTGCAG TGCCCCGTAC 
TCTGCCCTGT CCGCTTCCTT CCCCGGCATC GGGGCGACCT TCGATGAGTC TGGATCTTAC 
AGTGTCAACC TGAGCCTGGC TCCAGCTGGA GTCATTAGAG TGCCAGCTCA TCGGCCCATT 
CCCGGCGCTG TGCCACCTCC CATCTCCAGC GCCATCCCCG CCATGCCAGC TGTGCCCGGC 
CTTGGCAGCC TCAACTTCCC CTGGATGGAA AGCAGCAGGC GATTCGTGAA GGAAAGATTA 
ACAGCTGCAG CAGCCCTGAC GCCTTTCACT GTGACCCGCA GAATTGGGCA CCCCTATCAG 
AACCGAACCC CACCCAAGCG CAAAAAGCCT CGTACTTCTT TCTCAAGGGT GCAGATCTGT 
GAGCTGGAGA AGCGATTTCA TCGCCAGAAG TACTTGGCAT CTGCGGAAAG AGCAGCTTTA 
GCCAAATCTC TCAAAATGAC AGATGCCCAA GTCAAAACGT GGTTCCAAAA CAGGAGGACA 
AAGTGGAGGA GACAGACAGC AGAAGAGAGA GAAGCCGAGA GGCAGCAGGC GAACAGATTG 
ATGCTACAGC TCCAACACGA CGCGTTTCAA AAATCGCTGA GCGATTCGAT TCAGCCGGAT 
CCTTTGTGTT TGCACAATTC TTCTCTATTT GCACTTCAAA ACTTGCAGCC TTGGGATGAA 
GAGCAGTCTA AAATCCCCCC AGTTACCTCA TTAGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001015902.1
CDS	25..903
Translation	MDQPTSAQTQHQHEPISFGIDQILSSSDQENSSQSSAAAAVRGSEGSYLGSPVSRCSAPYSALSASFPGIGATFDESGSYSVNLSLAPAGVIRVPAHRPIPGAVPPPISSAIPAMPAVPGLGSLNFPWMESSRRFVKERLTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRLMLQLQHDAFQKSLSDSIQPDPLCLHNSSLFALQNLQPWDEEQSKIPPVTSLV

Target ORF information:

RefSeq Version	NM_001015902.2
Organism	Xenopus tropicalis(tropical clawed frog)
Definition	Xenopus tropicalis T cell leukemia homeobox 3 (tlx3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001015902.2

ORF Insert Sequence:

ATGGATCAGC CAACAAGTGC GCAGACCCAG CACCAACACG AACCCATCAG TTTCGGGATT 
GATCAGATAT TAAGCAGTTC CGATCAGGAA AACTCTTCCC AGTCGTCGGC CGCCGCCGCT 
GTCCGGGGCT CGGAGGGCAG TTACCTGGGG AGCCCAGTGA GTCGCTGCAG TGCCCCGTAC 
TCTGCCCTGT CCGCTTCCTT CCCCGGCATC GGGGCGACCT TCGATGAGTC TGGATCTTAC 
AGTGTCAACC TGAGCCTGGC TCCAGCTGGA GTCATTAGAG TGCCAGCTCA TCGGCCCATT 
CCCGGCGCTG TGCCACCTCC CATCTCCAGC GCCATCCCCG CCATGCCAGC TGTGCCCGGC 
CTTGGCAGCC TCAACTTCCC CTGGATGGAA AGCAGCAGGC GATTCGTGAA GGAAAGATTA 
ACAGCTGCAG CAGCCCTGAC GCCTTTCACT GTGACCCGCA GAATTGGGCA CCCCTATCAG 
AACCGAACCC CACCCAAGCG CAAAAAGCCT CGTACTTCTT TCTCAAGGGT GCAGATCTGT 
GAGCTGGAGA AGCGATTTCA TCGCCAGAAG TACTTGGCAT CTGCGGAAAG AGCAGCTTTA 
GCCAAATCTC TCAAAATGAC AGATGCCCAA GTCAAAACGT GGTTCCAAAA CAGGAGGACA 
AAGTGGAGGA GACAGACAGC AGAAGAGAGA GAAGCCGAGA GGCAGCAGGC GAACAGATTG 
ATGCTACAGC TCCAACACGA CGCGTTTCAA AAATCGCTGA GCGATTCGAT TCAGCCGGAT 
CCTTTGTGTT TGCACAATTC TTCTCTATTT GCACTTCAAA ACTTGCAGCC TTGGGATGAA 
GAGCAGTCTA AAATCCCCCC AGTTACCTCA TTAGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

cJun integrates calcium activity and tlx3 expression to regulate neurotransmitter specification.
Nature neuroscience13(8)944-50(2010 Aug)
Marek KW,Kurtz LM,Spitzer NC