ucn1.L cDNA ORF clone, Xenopus laevis(African clawed frog)

Gene
Clones
gRNAs

Summary

Gene Symbol	ucn1.L
Entrez Gene ID	445843
Full Name	urocortin 1 precursor
Gene Type	protein-coding
Organism	Xenopus laevis(African clawed frog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001092960.2	NP_001086429.1	urocortin 1 L homeolog precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Urocortins of the South African clawed frog, Xenopus laevis: conservation of structure and function in tetrapod evolution.
Boorse GC, Crespi EJ, Dautzenberg FM, Denver RJ
Endocrinology146(11)4851-60(2005 Nov)

Evidence that urocortin I acts as a neurohormone to stimulate alpha MSH release in the toad Xenopus laevis.
Calle M, Corstens GJ, Wang L, Kozicz T, Denver RJ, Barendregt HP, Roubos EW
Brain research1040(1-2)14-28(2005 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Urocortin 1 released from neurohemal axon terminals in the pituitary neural lobe functions as a stimulatory neurohormone for alpha-melanophore-stimulating hormone (alpha MSH) release from melanotrope cells of the pituitary intermediate lobe.
Title: Evidence that urocortin I acts as a neurohormone to stimulate alpha MSH release in the toad Xenopus laevis.

The following ucn1.L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ucn1.L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OAf05231	NM_001092960.2 Latest version!	Xenopus laevis urocortin 1 L homeolog (ucn1.L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ucn1.L ( NM_001092960.2 ) cDNA ORF clone, Xenopus laevis(African clawed frog) -> NP_001086429.1 Xenopus laevis urocortin 1 L homeolog (ucn1.L), mRNA.

Price & Availability↑

CloneID	OAf05231
Clone ID Related Accession (Same CDS sequence)	NM_001092960.2
Accession Version	NM_001092960.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-10-16
Organism	Xenopus laevis(African clawed frog)
Product	urocortin 1 L homeolog precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY596827.1. On Sep 23, 2016 this sequence version replaced NM_001092960.1. ##Evidence-Data-START## Transcript is intronless :: AY596827.1 [ECO:0000345] ##Evidence-Data-END##

ATGAAGACTG CACTGTTGAC ACTGCTGACT TGTTATTTGA TCCTCACGGC TTACACAGGA 
GCTCGACCCT TTGCCAGAAG TATGTTTGAT AGCCACCAGC TTGGGTTAAA TGGGCTGTTA 
GGTGATGAAA ACACACAGGC ACTCTTGTAC TTCCTAAGGG AAAAAATTCA AAGAGAGATG 
GAAAGAGGAG ACCCTCGTGT TCAGCTCAGG CTCAGCAAAA GTTCCCTCTC CACAGGACAT 
CAGGATTTAG TTTCTGCTCT CAATGTGATA CAAACTGCAT TCCAGGAGGG CATCCCAGAT 
GAGTCTGCCA AAGGCTTCTT GGAAGCATTT TCTGATCGTT TGAAGAGAGA GGACCCTCCT 
ATCTCCATAG ACCTGACATT CCACATTCTC AGACAGATGA TAGAGATTGC CAAAACCCAA 
AATCAGAAGC AGCAGGCTGA ACAGAATCGA ATTATTTTTG ACTCTGTGGG GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001086429.1
CDS	1..477
Translation	MKTALLTLLTCYLILTAYTGARPFARSMFDSHQLGLNGLLGDENTQALLYFLREKIQREMERGDPRVQLRLSKSSLSTGHQDLVSALNVIQTAFQEGIPDESAKGFLEAFSDRLKREDPPISIDLTFHILRQMIEIAKTQNQKQQAEQNRIIFDSVGK

Target ORF information:

RefSeq Version	NM_001092960.2
Organism	Xenopus laevis(African clawed frog)
Definition	Xenopus laevis urocortin 1 L homeolog (ucn1.L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001092960.2

ORF Insert Sequence:

ATGAAGACTG CACTGTTGAC ACTGCTGACT TGTTATTTGA TCCTCACGGC TTACACAGGA 
GCTCGACCCT TTGCCAGAAG TATGTTTGAT AGCCACCAGC TTGGGTTAAA TGGGCTGTTA 
GGTGATGAAA ACACACAGGC ACTCTTGTAC TTCCTAAGGG AAAAAATTCA AAGAGAGATG 
GAAAGAGGAG ACCCTCGTGT TCAGCTCAGG CTCAGCAAAA GTTCCCTCTC CACAGGACAT 
CAGGATTTAG TTTCTGCTCT CAATGTGATA CAAACTGCAT TCCAGGAGGG CATCCCAGAT 
GAGTCTGCCA AAGGCTTCTT GGAAGCATTT TCTGATCGTT TGAAGAGAGA GGACCCTCCT 
ATCTCCATAG ACCTGACATT CCACATTCTC AGACAGATGA TAGAGATTGC CAAAACCCAA 
AATCAGAAGC AGCAGGCTGA ACAGAATCGA ATTATTTTTG ACTCTGTGGG GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Urocortins of the South African clawed frog, Xenopus laevis: conservation of structure and function in tetrapod evolution.
Endocrinology146(11)4851-60(2005 Nov)
Boorse GC,Crespi EJ,Dautzenberg FM,Denver RJ

Evidence that urocortin I acts as a neurohormone to stimulate alpha MSH release in the toad Xenopus laevis.
Brain research1040(1-2)14-28(2005 Apr)
Calle M,Corstens GJ,Wang L,Kozicz T,Denver RJ,Barendregt HP,Roubos EW