| Gene Symbol | IL18 |
| Entrez Gene ID | 397057 |
| Full Name | interleukin 18 |
| Synonyms | IL-18 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
ORF » Species Summary » Sus scrofa » IL18 cDNA ORF clone
| Gene Symbol | IL18 |
| Entrez Gene ID | 397057 |
| Full Name | interleukin 18 |
| Synonyms | IL-18 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| mRNA | Protein | Name |
|---|---|---|
| XM_005667326.2 | XP_005667383.1 | interleukin-18 isoform X1 |
| XM_005667327.2 | XP_005667384.1 | interleukin-18 isoform X2 |
| NM_213997.1 | NP_999162.1 | interleukin-18 |
IL-12 and IL-18 induce interferon-? production and de novo CD2 expression in porcine ?? T cells.
Sedlak C, Patzl M, Saalm?ller A, Gerner W
Developmental and comparative immunology47(1)115-22(2014 Nov)
Interleukin-18 expression in pig salivary glands and salivary content changes during acute immobilization stress.
Muneta Y, Minagawa Y, Nakane T, Shibahara T, Yoshikawa T, Omata Y
Stress (Amsterdam, Netherlands)14(5)549-56(2011 Sep)
Endometrial caspase 1 and interleukin-18 expression during the estrous cycle and peri-implantation period of porcine pregnancy and response to early exogenous estrogen administration.
Ashworth MD, Ross JW, Stein DR, White FJ, Desilva UW, Geisert RD
Reproductive biology and endocrinology : RB&E833(2010 Apr)
Cloning, in vitro expression, and bioactivity of interleukin-18 isolated from a domestic porcine breed found in Henan.
Chen HY, Zheng LL, Li XS, Wei ZY, Cui BA, Li XK, Liu JP, Yin HZ, Meng JT, Zhang Y, Li SM
FEMS immunology and medical microbiology57(2)129-35(2009 Nov)
Immunosuppression of xenograft rejection in porcine kidney PK15 cells by porcine IL-18.
Choi YS, Kim YK, Shim JH, Kim EM, Kang HS, Yoon DY, Muneta Y, Myung PK
Experimental & molecular medicine38(5)574-82(2006 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Study reports that the monocyte-derived cytokines IL-12 and IL-18 act synergistically on porcine gammadelta T cells to induce IFN-gamma production. Additional stimuli such as the mitogen ConA and IL-2 are necessary to activate the cells for enhanced proliferation.
Title: IL-12 and IL-18 induce interferon-? production and de novo CD2 expression in porcine ?? T cells.
IL-18 concentration in saliva was significantly increased during a 60-min acute immobilization stress in thirteen 5-month-old pigs. These results are the first evidence of a stress-related change of IL-18 in pig saliva.
Title: Interleukin-18 expression in pig salivary glands and salivary content changes during acute immobilization stress.
endometrial expression of CASP1 and IL18 associated with pregnancy establishment; alteration of CASP1 and IL18 following premature exposure of uterus to estrogen during early pregnancy may contribute to conceptus loss between Days 15 to 18 of pregnancy
Title: Endometrial caspase 1 and interleukin-18 expression during the estrous cycle and peri-implantation period of porcine pregnancy and response to early exogenous estrogen administration.
Porcine IL-18 regulates anti-pig cellular rejection in C57BL/6 mice.
Title: Immunosuppression of xenograft rejection in porcine kidney PK15 cells by porcine IL-18.
The following IL18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe16268 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005667326.2 , NM_213997.1 | |
| Accession Version | NM_213997.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Sus scrofa(pig) | |
| Product | interleukin-18 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB010003.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB010003.1, EW529515.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01048372, SAMN01048373 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCTGCTG AACCGGAAGA CAATTGCATC AGCTTTGTGG AAATGAAGTT TATTAACAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_999162.1 |
| CDS | 1..579 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_213997.1 |
1 | ATGGCTGCTG AACCGGAAGA CAATTGCATC AGCTTTGTGG AAATGAAGTT TATTAACAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe16268 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005667326.2 , NM_213997.1 | |
| Accession Version | XM_005667326.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-05-12 | |
| Organism | Sus scrofa(pig) | |
| Product | interleukin-18 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010451.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005667326.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCTGCTG AACCGGAAGA CAATTGCATC AGCTTTGTGG AAATGAAGTT TATTAACAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_005667383.1 |
| CDS | 227..805 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_005667326.2 |
1 | ATGGCTGCTG AACCGGAAGA CAATTGCATC AGCTTTGTGG AAATGAAGTT TATTAACAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe16269 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005667327.2 | |
| Accession Version | XM_005667327.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-05-12 | |
| Organism | Sus scrofa(pig) | |
| Product | interleukin-18 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010451.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005667327.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCTGCTG AACCGGAAGA CAATTGCATC AGCTTTGTGG AAATGAAGTT TATTAACAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_005667384.1 |
| CDS | 201..776 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_005667327.2 |
1 | ATGGCTGCTG AACCGGAAGA CAATTGCATC AGCTTTGTGG AAATGAAGTT TATTAACAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
IL-12 and IL-18 induce interferon-? production and de novo CD2 expression in porcine ?? T cells. |
Interleukin-18 expression in pig salivary glands and salivary content changes during acute immobilization stress. |
Endometrial caspase 1 and interleukin-18 expression during the estrous cycle and peri-implantation period of porcine pregnancy and response to early exogenous estrogen administration. |
Cloning, in vitro expression, and bioactivity of interleukin-18 isolated from a domestic porcine breed found in Henan. |
Immunosuppression of xenograft rejection in porcine kidney PK15 cells by porcine IL-18. |