Sin3b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sin3b
Entrez Gene ID	683381
Full Name	SIN3 transcription regulator family member B
General protein information	Preferred Names SIN3 transcription regulator family member B Names paired amphipathic helix protein Sin3b SIN3 homolog B, transcription regulator SIN3 transcription regulator homolog B transcriptional regulator, SIN3B
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16p14

mRNA and Protein(s)

mRNA	Protein	Name
NM_001115038.2	NP_001108510.1	paired amphipathic helix protein Sin3b
NM_001115038.1	NP_001108510.1	paired amphipathic helix protein Sin3b

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression.
Vega AV, Avila G, Matthews G
Scientific reports32809(2013 Sep)

RNF220, an E3 ubiquitin ligase that targets Sin3B for ubiquitination.
Kong Q, Zeng W, Wu J, Hu W, Li C, Mao B
Biochemical and biophysical research communications393(4)708-13(2010 Mar)

Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?
Costa Y, Speed RM, Gautier P, Semple CA, Maratou K, Turner JM, Cooke HJ
Human molecular genetics15(15)2324-34(2006 Aug)

Mnt transcriptional repressor is functionally regulated during cell cycle progression.
Popov N, Wahlstr?m T, Hurlin PJ, Henriksson M
Oncogene24(56)8326-37(2005 Dec)

The winged-helix/forkhead protein myocyte nuclear factor beta (MNF-beta) forms a co-repressor complex with mammalian sin3B.
Yang Q, Kong Y, Rothermel B, Garry DJ, Bassel-Duby R, Williams RS
The Biochemical journal345 Pt 2335-43(2000 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

interaction with Sin3B influences Na(v)-channel trafficking or stability in the membrane.
Title: Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression.

The following Sin3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sin3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13293	NM_001115038.1 Latest version!	Rattus norvegicus SIN3 transcription regulator family member B (Sin3b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa63325	NM_001115038.2 Latest version!	Rattus norvegicus SIN3 transcription regulator family member B (Sin3b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sin3b ( NM_001115038.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001108510.1 Rattus norvegicus SIN3 transcription regulator family member B (Sin3b), mRNA.

Price & Availability↑

CloneID	ORa13293
Clone ID Related Accession (Same CDS sequence)	NM_001115038.1
Accession Version	NM_001115038.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	paired amphipathic helix protein Sin3b
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474031.2. On or before Mar 2, 2008 this sequence version replaced XM_001062859.1, XM_001062980.1. ##Evidence-Data-START## Transcript exon combination :: FQ220509.1, FQ220565.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGGCGCACG CAGGCGGTGG AGGCTCCGCG GGCCGGGGAT TCGGTGGCTC CCGCTGGGGT 
CGTTCGGGCT CTGGGGGGCA CGAGAAGCTG CCAGTGCACG TGGAGGATGC TCTCACCTAC 
CTCGACCAGG TGAAGATCCG CTTTGGCAGT GACCCTGCCA CCTACAACGG CTTCCTGGAG 
ATCATGAAGG AGTTCAAAAG CCAGAGCATT GACACCCCCG GCGTGATTAG GCGTGTGTCC 
CAGCTCTTCC ATGAGCACCC TGACCTCATC GTGGGGTTTA ATGCTTTCCT TCCGCTTGGA 
TACCGCATAG ACATTCCCAA GAACGGCAAG TTGAACATCC AGTCACCTCT GAGCAACCAG 
GACAACTCTC ATAGCCATGG TGACTGTGGG GAGGACTTCA AGCAGATGTC CTACAAGGAG 
GACAGAGGCC AGGTGCCCCT GGAGTCCGAC TCTGTGGAGT TCAACAATGC TATCAGCTAT 
GTGAACAAGA TCAAGACCCG CTTTCTGGAC CACCCTGAGA TCTACAGGTC CTTCCTGGAG 
ATCCTACACA CCTACCAGAA GGAGCAGCTG CACACTAAGG GTCGTCCATT CCGTGGCATG 
TCTGAGGAGG AAGTCTTCAC AGAGGTGGCC AATCTCTTCC GTGGTCAGGA GGACCTACTG 
TCAGAGTTCG GACAGTTCCT GCCTGAGGCA AAGCGGTCCC TGTTTACAGG CAATGGGTCG 
TGCGAGATGA ACAGCGCACA GAAGAATGAG GAGAAGAGTC TGGAACACAA GAAGCGCTCG 
CGGCCTTCAC TGCTGCGCCC TGTGTCTGCG CCAGCCAAGG TGGGGCTGCA GTTGAAATGT 
GCAGTTGTGT GGTTTGGTTA CTGCACAGCT GAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001108510.1
CDS	100..978
Translation	MAHAGGGGSAGRGFGGSRWGRSGSGGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLSNQDNSHSHGDCGEDFKQMSYKEDRGQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLHTKGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGSCEMNSAQKNEEKSLEHKKRSRPSLLRPVSAPAKVGLQLKCAVVWFGYCTAEE

Target ORF information:

RefSeq Version	NM_001115038.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SIN3 transcription regulator family member B (Sin3b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001115038.1

ORF Insert Sequence:

ATGGCGCACG CAGGCGGTGG AGGCTCCGCG GGCCGGGGAT TCGGTGGCTC CCGCTGGGGT 
CGTTCGGGCT CTGGGGGGCA CGAGAAGCTG CCAGTGCACG TGGAGGATGC TCTCACCTAC 
CTCGACCAGG TGAAGATCCG CTTTGGCAGT GACCCTGCCA CCTACAACGG CTTCCTGGAG 
ATCATGAAGG AGTTCAAAAG CCAGAGCATT GACACCCCCG GCGTGATTAG GCGTGTGTCC 
CAGCTCTTCC ATGAGCACCC TGACCTCATC GTGGGGTTTA ATGCTTTCCT TCCGCTTGGA 
TACCGCATAG ACATTCCCAA GAACGGCAAG TTGAACATCC AGTCACCTCT GAGCAACCAG 
GACAACTCTC ATAGCCATGG TGACTGTGGG GAGGACTTCA AGCAGATGTC CTACAAGGAG 
GACAGAGGCC AGGTGCCCCT GGAGTCCGAC TCTGTGGAGT TCAACAATGC TATCAGCTAT 
GTGAACAAGA TCAAGACCCG CTTTCTGGAC CACCCTGAGA TCTACAGGTC CTTCCTGGAG 
ATCCTACACA CCTACCAGAA GGAGCAGCTG CACACTAAGG GTCGTCCATT CCGTGGCATG 
TCTGAGGAGG AAGTCTTCAC AGAGGTGGCC AATCTCTTCC GTGGTCAGGA GGACCTACTG 
TCAGAGTTCG GACAGTTCCT GCCTGAGGCA AAGCGGTCCC TGTTTACAGG CAATGGGTCG 
TGCGAGATGA ACAGCGCACA GAAGAATGAG GAGAAGAGTC TGGAACACAA GAAGCGCTCG 
CGGCCTTCAC TGCTGCGCCC TGTGTCTGCG CCAGCCAAGG TGGGGCTGCA GTTGAAATGT 
GCAGTTGTGT GGTTTGGTTA CTGCACAGCT GAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sin3b ( NM_001115038.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001108510.1 Rattus norvegicus SIN3 transcription regulator family member B (Sin3b), mRNA.

Price & Availability↑

CloneID	ORa63325
Clone ID Related Accession (Same CDS sequence)	NM_001115038.2
Accession Version	NM_001115038.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-10
Organism	Rattus norvegicus(Norway rat)
Product	paired amphipathic helix protein Sin3b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FQ220717.1. On Sep 11, 2019 this sequence version replaced NM_001115038.1. ##Evidence-Data-START## Transcript exon combination :: FQ229609.1, FQ220358.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGGCGCACG CAGGCGGTGG AGGCTCCGCG GGCCGGGGAT TCGGTGGCTC CCGCTGGGGT 
CGTTCGGGCT CTGGGGGGCA CGAGAAGCTG CCAGTGCACG TGGAGGATGC TCTCACCTAC 
CTCGACCAGG TGAAGATCCG CTTTGGCAGT GACCCTGCCA CCTACAACGG CTTCCTGGAG 
ATCATGAAGG AGTTCAAAAG CCAGAGCATT GACACCCCCG GCGTGATTAG GCGTGTGTCC 
CAGCTCTTCC ATGAGCACCC TGACCTCATC GTGGGGTTTA ATGCTTTCCT TCCGCTTGGA 
TACCGCATAG ACATTCCCAA GAACGGCAAG TTGAACATCC AGTCACCTCT GAGCAACCAG 
GACAACTCTC ATAGCCATGG TGACTGTGGG GAGGACTTCA AGCAGATGTC CTACAAGGAG 
GACAGAGGCC AGGTGCCCCT GGAGTCCGAC TCTGTGGAGT TCAACAATGC TATCAGCTAT 
GTGAACAAGA TCAAGACCCG CTTTCTGGAC CACCCTGAGA TCTACAGGTC CTTCCTGGAG 
ATCCTACACA CCTACCAGAA GGAGCAGCTA CACACTAAGG GTCGTCCATT CCGTGGCATG 
TCTGAGGAGG AAGTCTTCAC AGAGGTGGCC AATCTCTTCC GTGGTCAGGA GGACCTACTG 
TCAGAGTTCG GACAGTTCCT GCCTGAGGCA AAGCGGTCCC TGTTTACAGG CAATGGGTCG 
TGCGAGATGA ACAGCGCACA GAAGAATGAG GAGAAGAGTC TGGAACACAA GAAGCGCTCG 
CGGCCTTCAC TGCTGCGCCC TGTGTCTGCG CCAGCCAAGG TGGGGCTGCA GTTGAAATGT 
GCAGTTGTGT GGTTTGGTTA CTGCACAGCT GAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001108510.1
CDS	23..901
Translation	MAHAGGGGSAGRGFGGSRWGRSGSGGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLSNQDNSHSHGDCGEDFKQMSYKEDRGQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLHTKGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGSCEMNSAQKNEEKSLEHKKRSRPSLLRPVSAPAKVGLQLKCAVVWFGYCTAEE

Target ORF information:

RefSeq Version	NM_001115038.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SIN3 transcription regulator family member B (Sin3b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001115038.2

ORF Insert Sequence:

ATGGCGCACG CAGGCGGTGG AGGCTCCGCG GGCCGGGGAT TCGGTGGCTC CCGCTGGGGT 
CGTTCGGGCT CTGGGGGGCA CGAGAAGCTG CCAGTGCACG TGGAGGATGC TCTCACCTAC 
CTCGACCAGG TGAAGATCCG CTTTGGCAGT GACCCTGCCA CCTACAACGG CTTCCTGGAG 
ATCATGAAGG AGTTCAAAAG CCAGAGCATT GACACCCCCG GCGTGATTAG GCGTGTGTCC 
CAGCTCTTCC ATGAGCACCC TGACCTCATC GTGGGGTTTA ATGCTTTCCT TCCGCTTGGA 
TACCGCATAG ACATTCCCAA GAACGGCAAG TTGAACATCC AGTCACCTCT GAGCAACCAG 
GACAACTCTC ATAGCCATGG TGACTGTGGG GAGGACTTCA AGCAGATGTC CTACAAGGAG 
GACAGAGGCC AGGTGCCCCT GGAGTCCGAC TCTGTGGAGT TCAACAATGC TATCAGCTAT 
GTGAACAAGA TCAAGACCCG CTTTCTGGAC CACCCTGAGA TCTACAGGTC CTTCCTGGAG 
ATCCTACACA CCTACCAGAA GGAGCAGCTA CACACTAAGG GTCGTCCATT CCGTGGCATG 
TCTGAGGAGG AAGTCTTCAC AGAGGTGGCC AATCTCTTCC GTGGTCAGGA GGACCTACTG 
TCAGAGTTCG GACAGTTCCT GCCTGAGGCA AAGCGGTCCC TGTTTACAGG CAATGGGTCG 
TGCGAGATGA ACAGCGCACA GAAGAATGAG GAGAAGAGTC TGGAACACAA GAAGCGCTCG 
CGGCCTTCAC TGCTGCGCCC TGTGTCTGCG CCAGCCAAGG TGGGGCTGCA GTTGAAATGT 
GCAGTTGTGT GGTTTGGTTA CTGCACAGCT GAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression.
Scientific reports32809(2013 Sep)
Vega AV,Avila G,Matthews G

RNF220, an E3 ubiquitin ligase that targets Sin3B for ubiquitination.
Biochemical and biophysical research communications393(4)708-13(2010 Mar)
Kong Q,Zeng W,Wu J,Hu W,Li C,Mao B

Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?
Human molecular genetics15(15)2324-34(2006 Aug)
Costa Y,Speed RM,Gautier P,Semple CA,Maratou K,Turner JM,Cooke HJ

Mnt transcriptional repressor is functionally regulated during cell cycle progression.
Oncogene24(56)8326-37(2005 Dec)
Popov N,Wahlstr?m T,Hurlin PJ,Henriksson M

The winged-helix/forkhead protein myocyte nuclear factor beta (MNF-beta) forms a co-repressor complex with mammalian sin3B.
The Biochemical journal345 Pt 2335-43(2000 Jan)
Yang Q,Kong Y,Rothermel B,Garry DJ,Bassel-Duby R,Williams RS