Epm2aip1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Epm2aip1
Entrez Gene ID	316021
Full Name	EPM2A interacting protein 1
General protein information	Preferred Names EPM2A interacting protein 1 Names EPM2A-interacting protein 1 EPM2A (laforin) interacting protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q32

mRNA and Protein(s)

mRNA	Protein	Name
NM_001271384.1	NP_001258313.1	EPM2A-interacting protein 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	EPM2AIP1	XP_526480.1
Bos taurus (cattle)	EPM2AIP1	XP_005222648.1
Canis lupus familiaris (dog)	EPM2AIP1	XP_005634284.1
	EPM2AIP1	XP_001090676.1
Rattus norvegicus (Norway rat)	Epm2aip1	NP_001258313.1
Homo sapiens (human)	EPM2AIP1	NP_055620.1
Mus musculus (house mouse)	Epm2aip1	NP_780475.1

Gene Ontology
Bibliography

Related articles in PubMed

Deficiency of a glycogen synthase-associated protein, Epm2aip1, causes decreased glycogen synthesis and hepatic insulin resistance.
Turnbull J, Tiberia E, Pereira S, Zhao X, Pencea N, Wheeler AL, Yu WQ, Ivovic A, Naranian T, Israelian N, Draginov A, Piliguian M, Frankland PW, Wang P, Ackerley CA, Giacca A, Minassian BA
The Journal of biological chemistry288(48)34627-37(2013 Nov)

Laforin preferentially binds the neurotoxic starch-like polyglucosans, which form in its absence in progressive myoclonus epilepsy.
Chan EM, Ackerley CA, Lohi H, Ianzano L, Cortez MA, Shannon P, Scherer SW, Minassian BA
Human molecular genetics13(11)1117-29(2004 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Epm2aip1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Epm2aip1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa41742	NM_001271384.1 Latest version!	Rattus norvegicus EPM2A interacting protein 1 (Epm2aip1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Epm2aip1 ( NM_001271384.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001258313.1 Rattus norvegicus EPM2A interacting protein 1 (Epm2aip1), mRNA.

Price & Availability↑

CloneID	ORa41742
Clone ID Related Accession (Same CDS sequence)	NM_001271384.1
Accession Version	NM_001271384.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1821bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	EPM2A-interacting protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC122675.6. On or before Sep 21, 2012 this sequence version replaced XM_003754461.1, XM_236659.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. COMPLETENESS: complete on the 3' end.

ATGTGGATGA CGCCCAAGAG GATTAGGATG GAAGTCGACG AGGCTCTGGT GTTTCGGCCC 
GAGTGGACCC AGCGTTACCT GGTGGTGGAG CCTGCGGAGG GTGACGGGGC CCTGTGCCTG 
GTGTGTCGCC GCCTGGTCGC CTCTACTCGG GAACGCGACG TGAGGCGCCA CTACGAAGCC 
GAACACGAAT TCTACGAACG GTTTGTAGGG GACGAGGAAC GCGCGGCCCT GGTGGAGCGT 
CTGCGGCAGG GCGACATGTC TTTGGCTGCC GTTCTCACTC CGGAGGAGAG AGCTACGCGG 
GCAGGCCTCG GCCTCTGCCG CTTCTTGGCC TTGAAGGGTC GCGGCTGGGG TGAGGGTGAC 
TTCGTTCACC AGTGCATGGA GGTGTTGCTG AGAGAGGTGC TGCCGGATCA CGTCGGCGTC 
CTGGAAGGCA TTGATTTATC TCCAGAGATC ACACGGCAGA GAATTCTGAG CATTGACAGC 
AACCTCCGTA GCCAGCTGTT TAACCGAGCC AGGGACTTTA AGGCCTATTC CCTTGCTTTG 
GATGACCAGG CTTTTGTGGC CTATGAGAAC TACCTGCTGG TTTTCATCCG TGGCGTCGGC 
CGCGACCTGG AGGTGCAAGA AGATCTTCTG ACCATTATCA ACCTGACTCA TCACTTCAGT 
GTTGGGGCTC TCATGTCGGC AATTCTGGAG GCCCTGCAGA CAGCAGGGCT CAGCTTACAG 
CGAATGGTTG GACTGACCAC GACCCACACC TTGAGGATGA TTGGCGAGAA CTCCGGACTG 
GTCTCCTACA TGAGAGAAAA GGCTGTGAGT CCCAACTGTT GGAACGTTAT CCACTATTCA 
GGATTTCTTC ACTTGGAACT GTTGAGTTCT TACGATGTTG ATATTAATCA GATCATAAAT 
ACCATCTCCG AATGGGTAGT CATGATTAAA ACCAGAGGTG TTAGGCGGCC AGAGTTCCAG 
TCTTTACTGA CTGAGTCTGA ATCAGAGCAT GGAGAGAGAG TTAATGGACG GTGTTTGAAC 
AACTGGCTGA GAAGAGGCAA AACGTTAAAA CTAATATTTT CGCTAAGGAA AGAAATCGAG 
GCGTTCTTGG TTTCGGTGGG GGCAACAACA GTTCATTTCT CAGACAAGCA GTGGCTTTGT 
GATTTCGGTT TCTTGGTAGA CATCATGGAT TACCTCCGAG AGATCAGTGA AGAACTGCAA 
ATCAGTAAAG TCTTTGCTGC TGCCGCCTTT GAACGCATCT GCACCTTTGA GGATAAGCTG 
AGCTCCCTTC AGAGACATAT GGAAGAAGTA AATCTAACAG ACTTTCCTGC CTTCAGCATA 
ATCGTTGATG AACTCAAACA GCAGTTTAAG GAAGATCAAA AAATATTTGA TCCTGACAGG 
TATCAAATGG TGATCTCCCG CCTACAAAAA GATTTTGAGA GACATTTCAA GGACCTCAGG 
TTCATTAAAA AGGACTTGGA ACTTTTCTCA AATCCATTTA GCTTCAAACC GGAATATGCG 
CCTATTTCCG TAAGAGTGGA GCTAACAAAA CTTCAGGGGA ACACCGACCT GTGGAATGAG 
TACAGAGTCA AAGACTTGGG ACAGTTTTAT GCTGGACTGT CTGGGGAAGC TTACCCAATT 
ATCAAAGGGG TTGCCTATAA GGTGGCATCC TTATTTGATA GTAACCAAAT CTGTGATAAG 
GCTTTTGCAT ATTTAACTCG AAACCAGCAC ACGTTGAGCC AGCCACTGAC GGACGAGCAT 
CTCCAAGCGC TATTTCGAGT TGCCACAACT GAAATGGATC CCCGTTGGGA TGATCTTGTG 
AGAGAGAGAA ATGACTCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258313.1
CDS	114..1934
Translation	MWMTPKRIRMEVDEALVFRPEWTQRYLVVEPAEGDGALCLVCRRLVASTRERDVRRHYEAEHEFYERFVGDEERAALVERLRQGDMSLAAVLTPEERATRAGLGLCRFLALKGRGWGEGDFVHQCMEVLLREVLPDHVGVLEGIDLSPEITRQRILSIDSNLRSQLFNRARDFKAYSLALDDQAFVAYENYLLVFIRGVGRDLEVQEDLLTIINLTHHFSVGALMSAILEALQTAGLSLQRMVGLTTTHTLRMIGENSGLVSYMREKAVSPNCWNVIHYSGFLHLELLSSYDVDINQIINTISEWVVMIKTRGVRRPEFQSLLTESESEHGERVNGRCLNNWLRRGKTLKLIFSLRKEIEAFLVSVGATTVHFSDKQWLCDFGFLVDIMDYLREISEELQISKVFAAAAFERICTFEDKLSSLQRHMEEVNLTDFPAFSIIVDELKQQFKEDQKIFDPDRYQMVISRLQKDFERHFKDLRFIKKDLELFSNPFSFKPEYAPISVRVELTKLQGNTDLWNEYRVKDLGQFYAGLSGEAYPIIKGVAYKVASLFDSNQICDKAFAYLTRNQHTLSQPLTDEHLQALFRVATTEMDPRWDDLVRERNDS

Target ORF information:

RefSeq Version	NM_001271384.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus EPM2A interacting protein 1 (Epm2aip1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271384.1

ORF Insert Sequence:

ATGTGGATGA CGCCCAAGAG GATTAGGATG GAAGTCGACG AGGCTCTGGT GTTTCGGCCC 
GAGTGGACCC AGCGTTACCT GGTGGTGGAG CCTGCGGAGG GTGACGGGGC CCTGTGCCTG 
GTGTGTCGCC GCCTGGTCGC CTCTACTCGG GAACGCGACG TGAGGCGCCA CTACGAAGCC 
GAACACGAAT TCTACGAACG GTTTGTAGGG GACGAGGAAC GCGCGGCCCT GGTGGAGCGT 
CTGCGGCAGG GCGACATGTC TTTGGCTGCC GTTCTCACTC CGGAGGAGAG AGCTACGCGG 
GCAGGCCTCG GCCTCTGCCG CTTCTTGGCC TTGAAGGGTC GCGGCTGGGG TGAGGGTGAC 
TTCGTTCACC AGTGCATGGA GGTGTTGCTG AGAGAGGTGC TGCCGGATCA CGTCGGCGTC 
CTGGAAGGCA TTGATTTATC TCCAGAGATC ACACGGCAGA GAATTCTGAG CATTGACAGC 
AACCTCCGTA GCCAGCTGTT TAACCGAGCC AGGGACTTTA AGGCCTATTC CCTTGCTTTG 
GATGACCAGG CTTTTGTGGC CTATGAGAAC TACCTGCTGG TTTTCATCCG TGGCGTCGGC 
CGCGACCTGG AGGTGCAAGA AGATCTTCTG ACCATTATCA ACCTGACTCA TCACTTCAGT 
GTTGGGGCTC TCATGTCGGC AATTCTGGAG GCCCTGCAGA CAGCAGGGCT CAGCTTACAG 
CGAATGGTTG GACTGACCAC GACCCACACC TTGAGGATGA TTGGCGAGAA CTCCGGACTG 
GTCTCCTACA TGAGAGAAAA GGCTGTGAGT CCCAACTGTT GGAACGTTAT CCACTATTCA 
GGATTTCTTC ACTTGGAACT GTTGAGTTCT TACGATGTTG ATATTAATCA GATCATAAAT 
ACCATCTCCG AATGGGTAGT CATGATTAAA ACCAGAGGTG TTAGGCGGCC AGAGTTCCAG 
TCTTTACTGA CTGAGTCTGA ATCAGAGCAT GGAGAGAGAG TTAATGGACG GTGTTTGAAC 
AACTGGCTGA GAAGAGGCAA AACGTTAAAA CTAATATTTT CGCTAAGGAA AGAAATCGAG 
GCGTTCTTGG TTTCGGTGGG GGCAACAACA GTTCATTTCT CAGACAAGCA GTGGCTTTGT 
GATTTCGGTT TCTTGGTAGA CATCATGGAT TACCTCCGAG AGATCAGTGA AGAACTGCAA 
ATCAGTAAAG TCTTTGCTGC TGCCGCCTTT GAACGCATCT GCACCTTTGA GGATAAGCTG 
AGCTCCCTTC AGAGACATAT GGAAGAAGTA AATCTAACAG ACTTTCCTGC CTTCAGCATA 
ATCGTTGATG AACTCAAACA GCAGTTTAAG GAAGATCAAA AAATATTTGA TCCTGACAGG 
TATCAAATGG TGATCTCCCG CCTACAAAAA GATTTTGAGA GACATTTCAA GGACCTCAGG 
TTCATTAAAA AGGACTTGGA ACTTTTCTCA AATCCATTTA GCTTCAAACC GGAATATGCG 
CCTATTTCCG TAAGAGTGGA GCTAACAAAA CTTCAGGGGA ACACCGACCT GTGGAATGAG 
TACAGAGTCA AAGACTTGGG ACAGTTTTAT GCTGGACTGT CTGGGGAAGC TTACCCAATT 
ATCAAAGGGG TTGCCTATAA GGTGGCATCC TTATTTGATA GTAACCAAAT CTGTGATAAG 
GCTTTTGCAT ATTTAACTCG AAACCAGCAC ACGTTGAGCC AGCCACTGAC GGACGAGCAT 
CTCCAAGCGC TATTTCGAGT TGCCACAACT GAAATGGATC CCCGTTGGGA TGATCTTGTG 
AGAGAGAGAA ATGACTCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Deficiency of a glycogen synthase-associated protein, Epm2aip1, causes decreased glycogen synthesis and hepatic insulin resistance.
The Journal of biological chemistry288(48)34627-37(2013 Nov)
Turnbull J,Tiberia E,Pereira S,Zhao X,Pencea N,Wheeler AL,Yu WQ,Ivovic A,Naranian T,Israelian N,Draginov A,Piliguian M,Frankland PW,Wang P,Ackerley CA,Giacca A,Minassian BA

Laforin preferentially binds the neurotoxic starch-like polyglucosans, which form in its absence in progressive myoclonus epilepsy.
Human molecular genetics13(11)1117-29(2004 Jun)
Chan EM,Ackerley CA,Lohi H,Ianzano L,Cortez MA,Shannon P,Scherer SW,Minassian BA