Epm2aip1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Epm2aip1
Entrez Gene ID	77781
Full Name	EPM2A (laforin) interacting protein 1
Synonyms	A930003G21Rik,mKIAA0766
General protein information	Preferred Names EPM2A (laforin) interacting protein 1 Names EPM2A-interacting protein 1 laforin-interacting protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 F3

mRNA and Protein(s)

mRNA	Protein	Name
NM_175266.4	NP_780475.1	EPM2A-interacting protein 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	EPM2AIP1	XP_526480.1
Bos taurus (cattle)	EPM2AIP1	XP_005222648.1
Canis lupus familiaris (dog)	EPM2AIP1	XP_005634284.1
	EPM2AIP1	XP_001090676.1
Rattus norvegicus (Norway rat)	Epm2aip1	NP_001258313.1
Homo sapiens (human)	EPM2AIP1	NP_055620.1
Mus musculus (house mouse)	Epm2aip1	NP_780475.1

Gene Ontology
Bibliography

Related articles in PubMed

Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome.
Pei L, Leblanc M, Barish G, Atkins A, Nofsinger R, Whyte J, Gold D, He M, Kawamura K, Li HR, Downes M, Yu RT, Powell HC, Lingrel JB, Evans RM
Nature medicine17(11)1466-72(2011 Oct)

Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Bulfone A, Carotenuto P, Faedo A, Aglio V, Garzia L, Bello AM, Basile A, Andr? A, Cocchia M, Guardiola O, Ballabio A, Rubenstein JL, Zollo M
The Journal of neuroscience : the official journal of the Society for Neuroscience25(33)7586-600(2005 Aug)

Laforin preferentially binds the neurotoxic starch-like polyglucosans, which form in its absence in progressive myoclonus epilepsy.
Chan EM, Ackerley CA, Lohi H, Ianzano L, Cortez MA, Shannon P, Scherer SW, Minassian BA
Human molecular genetics13(11)1117-29(2004 Jun)

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Okazaki N, Kikuno R, Ohara R, Inamoto S, Aizawa H, Yuasa S, Nakajima D, Nagase T, Ohara O, Koga H
DNA research : an international journal for rapid publication of reports on genes and genomes10(1)35-48(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We show that the absence of Epm2aip1 in mice impairs allosteric activation of GS by glucose 6-phosphate, decreases hepatic glycogen synthesis, increases liver fat, causes hepatic insulin resistance, and protects against age-related obesity
Title: Deficiency of a glycogen synthase-associated protein, Epm2aip1, causes decreased glycogen synthesis and hepatic insulin resistance.

The following Epm2aip1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Epm2aip1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu20973	NM_175266.4 Latest version!	Mus musculus EPM2A (laforin) interacting protein 1 (Epm2aip1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$356.30 $509.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Epm2aip1 ( NM_175266.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780475.1 Mus musculus EPM2A (laforin) interacting protein 1 (Epm2aip1), mRNA.

Price & Availability↑

CloneID	OMu20973
Clone ID Related Accession (Same CDS sequence)	NM_175266.4
Accession Version	NM_175266.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1821bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	EPM2A-interacting protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ125214.1, AK043518.1, AK033908.1, CD807865.1, AK122366.1 and CN530473.1. On May 23, 2007 this sequence version replaced NM_175266.3.

ATGTGGATGA CGCCCAAGAG GATTAGGATG GAAGTCGACG AGGCTCTGGT GTTCCGGCCC 
GAGTGGACCC AGCGATACCT GGTGGTGGAG CCTGCGGAGG GTGACGGGGC CCTGTGCCTG 
GTGTGTCGCC GCCTGGTCGC CTCTACTCGG GAACGCGACG TGAGGCGCCA CTACGAGGCC 
GAGCACGAAT TCTACGAGCG GTTTGTAGGG GACGAGGAAC GCGCGGCCCT GGTCGAGCGT 
CTGCGGCAGG GTGACATGTC TTTGGCCGCC GTGCTCACTC CGGAGGAGAG AGCGACCCGG 
GCAGGCCTCG GCCTCTGCCG CTTCTTGGCC TTGAAGGGTC GCGGCTGGGG TGAGGGTGAC 
TTCGTACACC AGTGCATGGA GGTGTTGCTG AGAGAGGTGC TGCCGGATCA CGTCGGCGTC 
CTGGAAGGCA TTGACTTGTC TCCAGAGATC ACACGGCAGA GGATTCTGAG CATTGACAGC 
AACCTCCGCA GCCAGCTGTT TAACCGAGCC AGGGACTTTA AGGCCTATTC CCTTGCTTTG 
GATGACCAGG CTTTTGTGGC CTATGAGAAC TACCTGCTGG TCTTCATCCG TGGCGTCGGC 
CGCGACCTGG AGGTGCAAGA AGATCTTCTG ACGATTATCA ACCTGACTCA TCACTTCAGT 
GTTGGGGCTC TCATGTCGGC AATTCTGGAA GCCCTGCAGA CAGCAGGGCT CAGCTTACAG 
CGAATGGTTG GACTGACCAC GACCCACACT TTAAGGATGA TCGGCGAGAA CTCCGGACTG 
GTCTCCTACA TGAGAGAGAA GGCCGTGAGT CCCAACTGTT GGAACGTAAT CCACTATTCG 
GGATTTCTTC ACTTGGAACT GTTGAGTTCT TATGATGTTG ATATTAATCA GATCATAAAT 
ACCATATCTG AATGGGTAGT TATGATTAAG ACCAGAGGTG TTAGGCGACC GGAGTTTCAG 
CCTCTACTAA CTGAGTCTGA GTCAGAGCAT GGTGAAAGAG TTAACGGACG GTGTTTGAAC 
AACTGGCTGA GAAGAGGCAA AACGTTAAAA CTAATATTTT CACTAAGAAA AGAAATCGAG 
GCGTTCTTGG TCTCAGTGGG GGCAACAACA GTTCATTTCT CAGACAAGCA GTGGCTTTGT 
GATTTTGGTT TCTTGGTAGA TATTATGGAC TATCTTCGAG AGATCAGTGA AGAACTGCAG 
ATCAGTAAAG TCTTTGCTGC TGCTGCCTTT GAACGCATCT GCACCTTTGA GGGTAAGCTG 
AGTTCACTTC AGAGACATAT GGAGGAAGTA AATCTAACAG ACTTTCCTGC CTTCAGTATA 
ATCGTTGATG AACTTAAACA GCAGTTTAAG GAAGATCAAA AAATATTTGA TCCTGACAGG 
TATCAAATGG TGATCTCCCG CCTACAGAAA GATTTTGAGA GACATTTTAA GGACCTCAGG 
TTCATTAAAA AGGACTTAGA ACTTTTCTCA AATCCATTTA GCTTTAAACC GGAATATGCG 
CCTATTTCTG TAAGAGTGGA GCTAACAAAA CTTCAGGCCA ACACTGACCT GTGGAATGAG 
TACAGAGTCA AAGACTTGGG ACAGTTTTAT GCAGGACTGT CTGGTGAAGC TTACCCAATT 
ATCAAAGGGG TTGCCTATAA GGTGGCATCC TTATTTGATA GTAACCAGAT CTGTGATAAG 
GCTTTTGCAT ATTTAACTCG AAACCAGCAC ACATTGAGCC AGCCACTGAC GGATGAGCAT 
CTCCAAGCAC TGTTTCGAGT TGCCACAACT GAAATGGATC CTCGTTGGGA TGATCTTGTG 
AGAGAAAGAA ATGATTCGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780475.1
CDS	117..1937
Translation	MWMTPKRIRMEVDEALVFRPEWTQRYLVVEPAEGDGALCLVCRRLVASTRERDVRRHYEAEHEFYERFVGDEERAALVERLRQGDMSLAAVLTPEERATRAGLGLCRFLALKGRGWGEGDFVHQCMEVLLREVLPDHVGVLEGIDLSPEITRQRILSIDSNLRSQLFNRARDFKAYSLALDDQAFVAYENYLLVFIRGVGRDLEVQEDLLTIINLTHHFSVGALMSAILEALQTAGLSLQRMVGLTTTHTLRMIGENSGLVSYMREKAVSPNCWNVIHYSGFLHLELLSSYDVDINQIINTISEWVVMIKTRGVRRPEFQPLLTESESEHGERVNGRCLNNWLRRGKTLKLIFSLRKEIEAFLVSVGATTVHFSDKQWLCDFGFLVDIMDYLREISEELQISKVFAAAAFERICTFEGKLSSLQRHMEEVNLTDFPAFSIIVDELKQQFKEDQKIFDPDRYQMVISRLQKDFERHFKDLRFIKKDLELFSNPFSFKPEYAPISVRVELTKLQANTDLWNEYRVKDLGQFYAGLSGEAYPIIKGVAYKVASLFDSNQICDKAFAYLTRNQHTLSQPLTDEHLQALFRVATTEMDPRWDDLVRERNDS

Target ORF information:

RefSeq Version	NM_175266.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus EPM2A (laforin) interacting protein 1 (Epm2aip1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175266.4

ORF Insert Sequence:

ATGTGGATGA CGCCCAAGAG GATTAGGATG GAAGTCGACG AGGCTCTGGT GTTCCGGCCC 
GAGTGGACCC AGCGATACCT GGTGGTGGAG CCTGCGGAGG GTGACGGGGC CCTGTGCCTG 
GTGTGTCGCC GCCTGGTCGC CTCTACTCGG GAACGCGACG TGAGGCGCCA CTACGAGGCC 
GAGCACGAAT TCTACGAGCG GTTTGTAGGG GACGAGGAAC GCGCGGCCCT GGTCGAGCGT 
CTGCGGCAGG GTGACATGTC TTTGGCCGCC GTGCTCACTC CGGAGGAGAG AGCGACCCGG 
GCAGGCCTCG GCCTCTGCCG CTTCTTGGCC TTGAAGGGTC GCGGCTGGGG TGAGGGTGAC 
TTCGTACACC AGTGCATGGA GGTGTTGCTG AGAGAGGTGC TGCCGGATCA CGTCGGCGTC 
CTGGAAGGCA TTGACTTGTC TCCAGAGATC ACACGGCAGA GGATTCTGAG CATTGACAGC 
AACCTCCGCA GCCAGCTGTT TAACCGAGCC AGGGACTTTA AGGCCTATTC CCTTGCTTTG 
GATGACCAGG CTTTTGTGGC CTATGAGAAC TACCTGCTGG TCTTCATCCG TGGCGTCGGC 
CGCGACCTGG AGGTGCAAGA AGATCTTCTG ACGATTATCA ACCTGACTCA TCACTTCAGT 
GTTGGGGCTC TCATGTCGGC AATTCTGGAA GCCCTGCAGA CAGCAGGGCT CAGCTTACAG 
CGAATGGTTG GACTGACCAC GACCCACACT TTAAGGATGA TCGGCGAGAA CTCCGGACTG 
GTCTCCTACA TGAGAGAGAA GGCCGTGAGT CCCAACTGTT GGAACGTAAT CCACTATTCG 
GGATTTCTTC ACTTGGAACT GTTGAGTTCT TATGATGTTG ATATTAATCA GATCATAAAT 
ACCATATCTG AATGGGTAGT TATGATTAAG ACCAGAGGTG TTAGGCGACC GGAGTTTCAG 
CCTCTACTAA CTGAGTCTGA GTCAGAGCAT GGTGAAAGAG TTAACGGACG GTGTTTGAAC 
AACTGGCTGA GAAGAGGCAA AACGTTAAAA CTAATATTTT CACTAAGAAA AGAAATCGAG 
GCGTTCTTGG TCTCAGTGGG GGCAACAACA GTTCATTTCT CAGACAAGCA GTGGCTTTGT 
GATTTTGGTT TCTTGGTAGA TATTATGGAC TATCTTCGAG AGATCAGTGA AGAACTGCAG 
ATCAGTAAAG TCTTTGCTGC TGCTGCCTTT GAACGCATCT GCACCTTTGA GGGTAAGCTG 
AGTTCACTTC AGAGACATAT GGAGGAAGTA AATCTAACAG ACTTTCCTGC CTTCAGTATA 
ATCGTTGATG AACTTAAACA GCAGTTTAAG GAAGATCAAA AAATATTTGA TCCTGACAGG 
TATCAAATGG TGATCTCCCG CCTACAGAAA GATTTTGAGA GACATTTTAA GGACCTCAGG 
TTCATTAAAA AGGACTTAGA ACTTTTCTCA AATCCATTTA GCTTTAAACC GGAATATGCG 
CCTATTTCTG TAAGAGTGGA GCTAACAAAA CTTCAGGCCA ACACTGACCT GTGGAATGAG 
TACAGAGTCA AAGACTTGGG ACAGTTTTAT GCAGGACTGT CTGGTGAAGC TTACCCAATT 
ATCAAAGGGG TTGCCTATAA GGTGGCATCC TTATTTGATA GTAACCAGAT CTGTGATAAG 
GCTTTTGCAT ATTTAACTCG AAACCAGCAC ACATTGAGCC AGCCACTGAC GGATGAGCAT 
CTCCAAGCAC TGTTTCGAGT TGCCACAACT GAAATGGATC CTCGTTGGGA TGATCTTGTG 
AGAGAAAGAA ATGATTCGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome.
Nature medicine17(11)1466-72(2011 Oct)
Pei L,Leblanc M,Barish G,Atkins A,Nofsinger R,Whyte J,Gold D,He M,Kawamura K,Li HR,Downes M,Yu RT,Powell HC,Lingrel JB,Evans RM

Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
The Journal of neuroscience : the official journal of the Society for Neuroscience25(33)7586-600(2005 Aug)
Bulfone A,Carotenuto P,Faedo A,Aglio V,Garzia L,Bello AM,Basile A,Andr? A,Cocchia M,Guardiola O,Ballabio A,Rubenstein JL,Zollo M

Laforin preferentially binds the neurotoxic starch-like polyglucosans, which form in its absence in progressive myoclonus epilepsy.
Human molecular genetics13(11)1117-29(2004 Jun)
Chan EM,Ackerley CA,Lohi H,Ianzano L,Cortez MA,Shannon P,Scherer SW,Minassian BA

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
DNA research : an international journal for rapid publication of reports on genes and genomes10(1)35-48(2003 Feb)
Okazaki N,Kikuno R,Ohara R,Inamoto S,Aizawa H,Yuasa S,Nakajima D,Nagase T,Ohara O,Koga H