Pmm2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pmm2
Entrez Gene ID	302915
Full Name	phosphomannomutase 2
General protein information	Preferred Names phosphomannomutase 2 Names phosphomannomutase 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106973.1	NP_001100443.1	phosphomannomutase 2
XM_006245755.2	XP_006245817.1	phosphomannomutase 2 isoform X1

Pathways from BioSystems

Homologies

	PMM2	XP_001102327.1
Bos taurus (cattle)	PMM2	NP_001030267.1
Oryza sativa (rice)	Os04g0682300	NP_001054295.1
Homo sapiens (human)	PMM2	NP_000294.1
Pan troglodytes (chimpanzee)	PMM2	XP_510805.3
Rattus norvegicus (Norway rat)	Pmm2	NP_001100443.1
Gallus gallus (chicken)	PMM2	NP_001026639.1
Kluyveromyces lactis	KLLA0D05709g	XP_453316.1
Eremothecium gossypii	AGOS_ABR236W	NP_983185.1
Schizosaccharomyces pombe (fission yeast)	pmm1	NP_594325.1
Arabidopsis thaliana (thale cress)	PMM	NP_182103.1
Caenorhabditis elegans (roundworm)	CELE_F52B11.2	NP_001255786.1
Saccharomyces cerevisiae (baker's yeast)	SEC53	NP_116609.1
Xenopus tropicalis (tropical clawed frog)	pmm1	NP_001106421.1
Canis lupus familiaris (dog)	PMM2	XP_547133.3
Mus musculus (house mouse)	Pmm2	NP_058577.1
Danio rerio (zebrafish)	pmm2	NP_956378.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011353	XP_309297.2
Magnaporthe oryzae (rice blast fungus)	MGG_01637	XP_003714625.1
Drosophila melanogaster (fruit fly)	CG10688	NP_648589.1
Neurospora crassa	NCU02829	XP_963786.1

Gene Ontology
Bibliography

Related articles in PubMed

Tissue distribution of the murine phosphomannomutases Pmm1 and Pmm2 during brain development.
Cromphout K, Keldermans L, Snellinx A, Collet JF, Gr?newald S, De Geest N, Sciot R, Vanschaftingen E, Jaeken J, Matthijs G, Hartmann D
The European journal of neuroscience22(4)991-6(2005 Aug)

PMM2 mutation spectrum, including 10 novel mutations, in a large CDG type 1A family material with a focus on Scandinavian families.
Bjursell C, Erlandson A, Nordling M, Nilsson S, Wahlstr?m J, Stibler H, Kristiansson B, Martinsson T
Human mutation16(5)395-400(2000 Nov)

Missense mutations in phosphomannomutase 2 gene in two Japanese families with carbohydrate-deficient glycoprotein syndrome type 1.
Kondo I, Mizugishi K, Yoneda Y, Hashimoto T, Kuwajima K, Yuasa I, Shigemoto K, Kuroda Y
Clinical genetics55(1)50-4(1999 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pmm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pmm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02660	NM_001106973.1 Latest version!	Rattus norvegicus phosphomannomutase 2 (Pmm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa32723	XM_006245755.2 Latest version!	Rattus norvegicus phosphomannomutase 2 (Pmm2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pmm2 ( NM_001106973.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100443.1 Rattus norvegicus phosphomannomutase 2 (Pmm2), mRNA.

Price & Availability↑

CloneID	ORa02660
Clone ID Related Accession (Same CDS sequence)	NM_001106973.1
Accession Version	NM_001106973.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	phosphomannomutase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474017.1. On or before Oct 4, 2007 this sequence version replaced XM_001078730.1, XM_220141.4. ##Evidence-Data-START## Transcript exon combination :: BC168922.1, FQ148930.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCCACGC TCTGTCTCTT TGACATGGAT GGGACCTTGA CTGCCCCGCG GCAGAAAATT 
ACAAAAGAAA TGGATGGCTT TCTTCAAAAA TTGAGACAGA AGACCAAGAT TGGAGTGGTA 
GGTGGGTCAG ATTTTGAGAA GCTGCAAGAG CAACTGGGAA ATGATGTGGT TGAGAAATAC 
GATTATGTGT TTCCAGAGAA TGGCTTGGTA GCGTACAAAG ATGGGAAGCT ATTGTGTAAA 
CAGAATATTC AAGGTCATCT GGGGGAGGCT GTGATCCAAG ACCTGATCAA CTACTGTCTG 
AGCTACATTG CAAAAATTAA ACTCCCTAAG AAAAGGGGAA CTTTCATTGA ATTCCGAAAT 
GGCATGTTGA ATGTGTCCCC CATTGGAAGA AGCTGCAGCC AAGAAGAACG AATTGAGTTC 
TATGAGCTCG ATAAAAAAGA ACATATACGG CAAAAGTTTG TAGCAGACCT CAGGAAGGAG 
TTTGCAGGGA AAGGCCTCAC GTTCTCCATA GGCGGCCAGA TCAGCTTTGA TGTGTTTCCT 
GATGGTTGGG ACAAGCGCTA TTGCCTGAGG CACCTGGAGC AAGCTGGCTA TAAGACCATT 
TATTTCTTTG GAGACAAGAC TATGCCAGGT GGCAATGACC ATGAGATCTT CACAGACCCC 
AGAACTGTGG GCTACACAGT GACAGCACCT GAAGACACAC GCAGGATCTG TGAGGAGCTC 
TTCCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100443.1
CDS	65..793
Translation	MATLCLFDMDGTLTAPRQKITKEMDGFLQKLRQKTKIGVVGGSDFEKLQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCKQNIQGHLGEAVIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKEHIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHLEQAGYKTIYFFGDKTMPGGNDHEIFTDPRTVGYTVTAPEDTRRICEELFP

Target ORF information:

RefSeq Version	NM_001106973.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus phosphomannomutase 2 (Pmm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106973.1

ORF Insert Sequence:

ATGGCCACGC TCTGTCTCTT TGACATGGAT GGGACCTTGA CTGCCCCGCG GCAGAAAATT 
ACAAAAGAAA TGGATGGCTT TCTTCAAAAA TTGAGACAGA AGACCAAGAT TGGAGTGGTA 
GGTGGGTCAG ATTTTGAGAA GCTGCAAGAG CAACTGGGAA ATGATGTGGT TGAGAAATAC 
GATTATGTGT TTCCAGAGAA TGGCTTGGTA GCGTACAAAG ATGGGAAGCT ATTGTGTAAA 
CAGAATATTC AAGGTCATCT GGGGGAGGCT GTGATCCAAG ACCTGATCAA CTACTGTCTG 
AGCTACATTG CAAAAATTAA ACTCCCTAAG AAAAGGGGAA CTTTCATTGA ATTCCGAAAT 
GGCATGTTGA ATGTGTCCCC CATTGGAAGA AGCTGCAGCC AAGAAGAACG AATTGAGTTC 
TATGAGCTCG ATAAAAAAGA ACATATACGG CAAAAGTTTG TAGCAGACCT CAGGAAGGAG 
TTTGCAGGGA AAGGCCTCAC GTTCTCCATA GGCGGCCAGA TCAGCTTTGA TGTGTTTCCT 
GATGGTTGGG ACAAGCGCTA TTGCCTGAGG CACCTGGAGC AAGCTGGCTA TAAGACCATT 
TATTTCTTTG GAGACAAGAC TATGCCAGGT GGCAATGACC ATGAGATCTT CACAGACCCC 
AGAACTGTGG GCTACACAGT GACAGCACCT GAAGACACAC GCAGGATCTG TGAGGAGCTC 
TTCCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pmm2 ( XM_006245755.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006245817.1 Rattus norvegicus phosphomannomutase 2 (Pmm2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa32723
Clone ID Related Accession (Same CDS sequence)	XM_006245755.2
Accession Version	XM_006245755.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 687bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	phosphomannomutase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006245755.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTCAG AGAAAATTAC AAAAGAAATG GATGGCTTTC TTCAAAAATT GAGACAGAAG 
ACCAAGATTG GAGTGGTAGG TGGGTCAGAT TTTGAGAAGC TGCAAGAGCA ACTGGGAAAT 
GATGTGGTTG AGAAATACGA TTATGTGTTT CCAGAGAATG GCTTGGTAGC GTACAAAGAT 
GGGAAGCTAT TGTGTAAACA GAATATTCAA GGTCATCTGG GGGAGGCTGT GATCCAAGAC 
CTGATCAACT ACTGTCTGAG CTACATTGCA AAAATTAAAC TCCCTAAGAA AAGGGGAACT 
TTCATTGAAT TCCGAAATGG CATGTTGAAT GTGTCCCCCA TTGGAAGAAG CTGCAGCCAA 
GAAGAACGAA TTGAGTTCTA TGAGCTCGAT AAAAAAGAAC ATATACGGCA AAAGTTTGTA 
GCAGACCTCA GGAAGGAGTT TGCAGGGAAA GGCCTCACGT TCTCCATAGG CGGCCAGATC 
AGCTTTGATG TGTTTCCTGA TGGTTGGGAC AAGCGCTATT GCCTGAGGCA CCTGGAGCAA 
GCTGGCTATA AGACCATTTA TTTCTTTGGA GACAAGACTA TGCCAGGTGG CAATGACCAT 
GAGATCTTCA CAGACCCCAG AACTGTGGGC TACACAGTGA CAGCACCTGA AGACACACGC 
AGGATCTGTG AGGAGCTCTT CCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006245817.1
CDS	453..1139
Translation	MDSEKITKEMDGFLQKLRQKTKIGVVGGSDFEKLQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCKQNIQGHLGEAVIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKEHIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHLEQAGYKTIYFFGDKTMPGGNDHEIFTDPRTVGYTVTAPEDTRRICEELFP

Target ORF information:

RefSeq Version	XM_006245755.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus phosphomannomutase 2 (Pmm2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006245755.2

ORF Insert Sequence:

ATGGACTCAG AGAAAATTAC AAAAGAAATG GATGGCTTTC TTCAAAAATT GAGACAGAAG 
ACCAAGATTG GAGTGGTAGG TGGGTCAGAT TTTGAGAAGC TGCAAGAGCA ACTGGGAAAT 
GATGTGGTTG AGAAATACGA TTATGTGTTT CCAGAGAATG GCTTGGTAGC GTACAAAGAT 
GGGAAGCTAT TGTGTAAACA GAATATTCAA GGTCATCTGG GGGAGGCTGT GATCCAAGAC 
CTGATCAACT ACTGTCTGAG CTACATTGCA AAAATTAAAC TCCCTAAGAA AAGGGGAACT 
TTCATTGAAT TCCGAAATGG CATGTTGAAT GTGTCCCCCA TTGGAAGAAG CTGCAGCCAA 
GAAGAACGAA TTGAGTTCTA TGAGCTCGAT AAAAAAGAAC ATATACGGCA AAAGTTTGTA 
GCAGACCTCA GGAAGGAGTT TGCAGGGAAA GGCCTCACGT TCTCCATAGG CGGCCAGATC 
AGCTTTGATG TGTTTCCTGA TGGTTGGGAC AAGCGCTATT GCCTGAGGCA CCTGGAGCAA 
GCTGGCTATA AGACCATTTA TTTCTTTGGA GACAAGACTA TGCCAGGTGG CAATGACCAT 
GAGATCTTCA CAGACCCCAG AACTGTGGGC TACACAGTGA CAGCACCTGA AGACACACGC 
AGGATCTGTG AGGAGCTCTT CCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tissue distribution of the murine phosphomannomutases Pmm1 and Pmm2 during brain development.
The European journal of neuroscience22(4)991-6(2005 Aug)
Cromphout K,Keldermans L,Snellinx A,Collet JF,Gr?newald S,De Geest N,Sciot R,Vanschaftingen E,Jaeken J,Matthijs G,Hartmann D

PMM2 mutation spectrum, including 10 novel mutations, in a large CDG type 1A family material with a focus on Scandinavian families.
Human mutation16(5)395-400(2000 Nov)
Bjursell C,Erlandson A,Nordling M,Nilsson S,Wahlstr?m J,Stibler H,Kristiansson B,Martinsson T

Missense mutations in phosphomannomutase 2 gene in two Japanese families with carbohydrate-deficient glycoprotein syndrome type 1.
Clinical genetics55(1)50-4(1999 Jan)
Kondo I,Mizugishi K,Yoneda Y,Hashimoto T,Kuwajima K,Yuasa I,Shigemoto K,Kuroda Y