Cdx4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdx4
Entrez Gene ID	302400
Full Name	caudal type homeo box 4
Synonyms	RGD1561529
General protein information	Preferred Names caudal type homeo box 4 Names homeobox protein CDX-4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106942.1	NP_001100412.1	homeobox protein CDX-4

Pathways from BioSystems

Homologies

	CDX4	XP_001095271.1
Canis lupus familiaris (dog)	CDX4	XP_549080.1
Homo sapiens (human)	CDX4	NP_005184.1
Pan troglodytes (chimpanzee)	CDX4	XP_529040.3
Bos taurus (cattle)	CDX4	XP_003588202.1
Mus musculus (house mouse)	Cdx4	NP_031700.1
Rattus norvegicus (Norway rat)	Cdx4	NP_001100412.1

Gene Ontology
Bibliography

Related articles in PubMed

HoxA10 activates CDX4 transcription and Cdx4 activates HOXA10 transcription in myeloid cells.
Bei L, Huang W, Wang H, Shah C, Horvath E, Eklund E
The Journal of biological chemistry286(21)19047-64(2011 May)

Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos.
Young T, Rowland JE, van de Ven C, Bialecka M, Novoa A, Carapuco M, van Nes J, de Graaff W, Duluc I, Freund JN, Beck F, Mallo M, Deschamps J
Developmental cell17(4)516-26(2009 Oct)

The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice.
van Nes J, de Graaff W, Lebrin F, Gerhard M, Beck F, Deschamps J
Development (Cambridge, England)133(3)419-28(2006 Feb)

Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation.
Niwa H, Toyooka Y, Shimosato D, Strumpf D, Takahashi K, Yagi R, Rossant J
Cell123(5)917-29(2005 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cdx4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdx4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02552	NM_001106942.1 Latest version!	Rattus norvegicus caudal type homeo box 4 (Cdx4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdx4 ( NM_001106942.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100412.1 Rattus norvegicus caudal type homeo box 4 (Cdx4), mRNA.

Price & Availability↑

CloneID	ORa02552
Clone ID Related Accession (Same CDS sequence)	NM_001106942.1
Accession Version	NM_001106942.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	homeobox protein CDX-4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473969.2. On or before Oct 4, 2007 this sequence version replaced XM_228569.2, XM_001055316.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN04563758, SAMN04563759 [ECO:0000348] ##Evidence-Data-END##

ATGTATGGAA GCTGCCTTTT AGAAAAAGAA GCGGGAATGT ACCCAGGCAC TCTCAGGAAC 
CCTGGAGGAG GCAGCACAGC CGGAGTGGGC ACCTCTGGGG GCAGTGGTAG TCCTCTGCCT 
GCCTCCAACT TTACTGCAGC CCCAGTTTAC CCACACTACA TGGGGTATCC ACATATGTCC 
AACATGGATC CTCACGGGCC TTCGCTGGGA GCCTGGAGCT CACCCTACAG TCCGCCCCGG 
GAAGACTGGA GTACATACCC TGGGCCGTCC AGCACAATGG GCACAGTGCC CATGAACGAC 
ATGACCTCGA GCTCCCCAGC TTTCGGCTCC CCAGACTACA GCACTCTGGG CCCCACTGGC 
GGTGCAGGCG GTGCAAGCAA CGGCGGTAGC CTGCCAGACG CGGCCAGCGA GTCACTGGTT 
TCCATCGACT CAGGCACCTC TGGCGGCGCC ACTTCTCCCA GCAGGAGCCG CCACAGCCCC 
TACGCGTGGA TGCGCAAGAC TGTGCAGGTG ACCGGGAAAA CCAGGACAAA AGAAAAGTAT 
CGTGTGGTCT ACACGGATCA TCAAAGGCTG GAGCTGGAAA AGGAATTTCA CTGCAATAGA 
TACATTACCA TCCGGAGGAA GTCAGAGCTG GCAGTTAACC TGGGCCTTTC TGAGAGACAG 
GTGAAAATCT GGTTTCAGAA TCGCAGAGCC AAGGAGAGGA AGATGATCAA AAAGAAAATC 
TCCCAGTTTG AGAACAGTGG AGGTTCCGTG CAAAGTGACT CTGGCTCCAT CAGCCCCGGA 
GAACTGCCTA ATGCTTTCTT CACCACTCCA TCTGCTGTCC GTGGGTTTCA GCCAATTGAG 
ATACAGCAGG TCATAATTTC TGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100412.1
CDS	171..1037
Translation	MYGSCLLEKEAGMYPGTLRNPGGGSTAGVGTSGGSGSPLPASNFTAAPVYPHYMGYPHMSNMDPHGPSLGAWSSPYSPPREDWSTYPGPSSTMGTVPMNDMTSSSPAFGSPDYSTLGPTGGAGGASNGGSLPDAASESLVSIDSGTSGGATSPSRSRHSPYAWMRKTVQVTGKTRTKEKYRVVYTDHQRLELEKEFHCNRYITIRRKSELAVNLGLSERQVKIWFQNRRAKERKMIKKKISQFENSGGSVQSDSGSISPGELPNAFFTTPSAVRGFQPIEIQQVIISE

Target ORF information:

RefSeq Version	NM_001106942.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus caudal type homeo box 4 (Cdx4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106942.1

ORF Insert Sequence:

ATGTATGGAA GCTGCCTTTT AGAAAAAGAA GCGGGAATGT ACCCAGGCAC TCTCAGGAAC 
CCTGGAGGAG GCAGCACAGC CGGAGTGGGC ACCTCTGGGG GCAGTGGTAG TCCTCTGCCT 
GCCTCCAACT TTACTGCAGC CCCAGTTTAC CCACACTACA TGGGGTATCC ACATATGTCC 
AACATGGATC CTCACGGGCC TTCGCTGGGA GCCTGGAGCT CACCCTACAG TCCGCCCCGG 
GAAGACTGGA GTACATACCC TGGGCCGTCC AGCACAATGG GCACAGTGCC CATGAACGAC 
ATGACCTCGA GCTCCCCAGC TTTCGGCTCC CCAGACTACA GCACTCTGGG CCCCACTGGC 
GGTGCAGGCG GTGCAAGCAA CGGCGGTAGC CTGCCAGACG CGGCCAGCGA GTCACTGGTT 
TCCATCGACT CAGGCACCTC TGGCGGCGCC ACTTCTCCCA GCAGGAGCCG CCACAGCCCC 
TACGCGTGGA TGCGCAAGAC TGTGCAGGTG ACCGGGAAAA CCAGGACAAA AGAAAAGTAT 
CGTGTGGTCT ACACGGATCA TCAAAGGCTG GAGCTGGAAA AGGAATTTCA CTGCAATAGA 
TACATTACCA TCCGGAGGAA GTCAGAGCTG GCAGTTAACC TGGGCCTTTC TGAGAGACAG 
GTGAAAATCT GGTTTCAGAA TCGCAGAGCC AAGGAGAGGA AGATGATCAA AAAGAAAATC 
TCCCAGTTTG AGAACAGTGG AGGTTCCGTG CAAAGTGACT CTGGCTCCAT CAGCCCCGGA 
GAACTGCCTA ATGCTTTCTT CACCACTCCA TCTGCTGTCC GTGGGTTTCA GCCAATTGAG 
ATACAGCAGG TCATAATTTC TGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HoxA10 activates CDX4 transcription and Cdx4 activates HOXA10 transcription in myeloid cells.
The Journal of biological chemistry286(21)19047-64(2011 May)
Bei L,Huang W,Wang H,Shah C,Horvath E,Eklund E

Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos.
Developmental cell17(4)516-26(2009 Oct)
Young T,Rowland JE,van de Ven C,Bialecka M,Novoa A,Carapuco M,van Nes J,de Graaff W,Duluc I,Freund JN,Beck F,Mallo M,Deschamps J

The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice.
Development (Cambridge, England)133(3)419-28(2006 Feb)
van Nes J,de Graaff W,Lebrin F,Gerhard M,Beck F,Deschamps J

Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation.
Cell123(5)917-29(2005 Dec)
Niwa H,Toyooka Y,Shimosato D,Strumpf D,Takahashi K,Yagi R,Rossant J