Lrrc6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lrrc6
Entrez Gene ID	299920
Full Name	leucine rich repeat containing 6
Synonyms	Lrtp,Tslrp
General protein information	Preferred Names leucine rich repeat containing 6 Names protein tilB homolog leucine rich repeat containing 6 (testis) leucine-rich testis-specific protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q34

mRNA and Protein(s)

mRNA	Protein	Name
NM_001025659.2	NP_001020830.2	protein tilB homolog

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Lrrc6	NP_062330.1
Homo sapiens (human)	LRRC6	NP_036604.2
Bos taurus (cattle)	LRRC6	NP_001069372.1
Danio rerio (zebrafish)	lrrc6	NP_001002311.1
Xenopus tropicalis (tropical clawed frog)	lrrc6	NP_001032332.1
Pan troglodytes (chimpanzee)	LRRC6	XP_519965.2
	LRRC6	XP_001085271.1
Rattus norvegicus (Norway rat)	Lrrc6	NP_001020830.2
Drosophila melanogaster (fruit fly)	tilB	NP_608460.1
Canis lupus familiaris (dog)	LRRC6	XP_005628002.1
Gallus gallus (chicken)	LRRC6	NP_001264385.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008927	XP_319679.2

Gene Ontology
Bibliography

Related articles in PubMed

Loss-of-function mutations in LRRC6, a gene essential for proper axonemal assembly of inner and outer dynein arms, cause primary ciliary dyskinesia.
Kott E, Duquesnoy P, Copin B, Legendre M, Dastot-Le Moal F, Montantin G, Jeanson L, Tamalet A, Papon JF, Siffroi JP, Rives N, Mitchell V, de Blic J, Coste A, Clement A, Escalier D, Tour? A, Escudier E, Amselem S
American journal of human genetics91(5)958-64(2012 Nov)

Identification of a novel testis-specific leucine-rich protein in humans and mice.
Xue JC, Goldberg E
Biology of reproduction62(5)1278-84(2000 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Identification and characterization of the mouse and human Lrrc6 (LRTP) orthologs.
Title: Identification of a novel testis-specific leucine-rich protein in humans and mice.

The following Lrrc6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lrrc6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07809	NM_001025659.2 Latest version!	Rattus norvegicus leucine rich repeat containing 6 (Lrrc6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lrrc6 ( NM_001025659.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001020830.2 Rattus norvegicus leucine rich repeat containing 6 (Lrrc6), mRNA.

Price & Availability↑

CloneID	ORa07809
Clone ID Related Accession (Same CDS sequence)	NM_001025659.2
Accession Version	NM_001025659.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1419bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	protein tilB homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC097394.1. On Oct 25, 2007 this sequence version replaced NM_001025659.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2689604 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCCGAA TCACAGAAGA TCTTATTAGA CGGAATGCTG AGCACAACGA ATGTGTAATT 
TTTTCCCTGG AGGAACTCTC CTTGCATCAG CAAGAAATAG AAAGACTAGA ACATATTGAC 
AAATGGTGCC GTGATTTAAA AATTCTCTAT CTTCAAAATA ACCTCATTGC AAAAATTGAA 
AATGTTAGCA AACTGAAGAA ACTTGAATAC TTGAACTTAG CATTGAACAA CATTGAAAGA 
ATTGAAAACT TGGAAGGATG TGAGTGGCTG ACCAAACTTG ACTTGACTGT AAATTTCATT 
GGAGAACTGA GTAGCATTAA AACCCTGACA CACAATATTC ATCTGAGGGA GCTATTCCTC 
GTGGGTAACC CATGTGCTGA CTTTGACGGC TACAGGGAGT TTGTGGTGGT GACCTTACAA 
CAGTTAAAGT GGTTGGATGG CAAAGAAATA GAACGTTCTG AAAGGATCCA AGCACTGCAG 
AACTACGCAG CAGTTGAACA GCAAATCAGA GAGCAGGAGA AAGCTTACTG CCTTAGACGT 
GCCAAAGAGA AAGAGGAAGC TCAGAGGAAA CTGGAGGAAG AAAACGAAAG TGAAGACAAA 
AAGAAGAGCA GCCCAGGCTT TGATGGGGAT TGTTACACAG ACATCCACGC TGATTGCCCA 
TCTGCCATGG AGAACAAAGA CCATCTTCAG GTACCAGAAA CACAAGAACA ACAACATAGC 
ACAAAGAAAT CAGATGAAAT TGAAGATGAT CTGGCATTCT GGAACAAACC GTCTTTGTTC 
ACTCCTGAAT CTAGATTGGA AACTCTCAGA CACATGGAAA AGCAACGCAA AGCCCAAGAT 
AAGTTAAGTG AAAAGAAAAA AAGAGTGAAA CCACCCCGGA CTTTGATTAC AGAAGATGGG 
AAGGTCCTGA ATGTGAATGA AGCCAAACTT GATTTCTCCT TGAAAGATGA TGAGAAACAC 
AACCAGATCA TCCTGGACCT GGCTGTCTAT AGGTACATGG ACACCTCTTT AATTGAGGTT 
GATGTGCAGC CAACCTATGT TCGAGTAATG GTCAAAGGAA AGCCATTTCA GCTTGCCCTT 
TCTGCAGAGG TCCAGCCTGA CAGCAGCTCT GCTAAAAGGT CTCAGACAAC AGGACATTTG 
CTGATCTGCA TGCCCAAGGT AGGAGAAATG ATCACAGGTC AACAAACACC CATGTCTGTG 
AAGACCGCCT CGGAGAGCAG CAAGGAACAA ACAAAGCCCA GAAGAAAGCA GGTAGAAAGA 
TTAGAAGTTG ATCCCAGCAA GCATTCCTGC CCTGATGTGT CTACTATAGT ACAAGAGAGA 
AAACACAAAC CCAAAAGGAT GGAATCTCAA CCACAAGTTG AACCCAGTGA GGCAGAGCCA 
GACTTTGACG ATAACCCAGA GGTGCCTCCA CTCATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020830.2
CDS	71..1489
Translation	MGRITEDLIRRNAEHNECVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIAKIENVSKLKKLEYLNLALNNIERIENLEGCEWLTKLDLTVNFIGELSSIKTLTHNIHLRELFLVGNPCADFDGYREFVVVTLQQLKWLDGKEIERSERIQALQNYAAVEQQIREQEKAYCLRRAKEKEEAQRKLEEENESEDKKKSSPGFDGDCYTDIHADCPSAMENKDHLQVPETQEQQHSTKKSDEIEDDLAFWNKPSLFTPESRLETLRHMEKQRKAQDKLSEKKKRVKPPRTLITEDGKVLNVNEAKLDFSLKDDEKHNQIILDLAVYRYMDTSLIEVDVQPTYVRVMVKGKPFQLALSAEVQPDSSSAKRSQTTGHLLICMPKVGEMITGQQTPMSVKTASESSKEQTKPRRKQVERLEVDPSKHSCPDVSTIVQERKHKPKRMESQPQVEPSEAEPDFDDNPEVPPLI

Target ORF information:

RefSeq Version	NM_001025659.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus leucine rich repeat containing 6 (Lrrc6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025659.2

ORF Insert Sequence:

ATGGGCCGAA TCACAGAAGA TCTTATTAGA CGGAATGCTG AGCACAACGA ATGTGTAATT 
TTTTCCCTGG AGGAACTCTC CTTGCATCAG CAAGAAATAG AAAGACTAGA ACATATTGAC 
AAATGGTGCC GTGATTTAAA AATTCTCTAT CTTCAAAATA ACCTCATTGC AAAAATTGAA 
AATGTTAGCA AACTGAAGAA ACTTGAATAC TTGAACTTAG CATTGAACAA CATTGAAAGA 
ATTGAAAACT TGGAAGGATG TGAGTGGCTG ACCAAACTTG ACTTGACTGT AAATTTCATT 
GGAGAACTGA GTAGCATTAA AACCCTGACA CACAATATTC ATCTGAGGGA GCTATTCCTC 
GTGGGTAACC CATGTGCTGA CTTTGACGGC TACAGGGAGT TTGTGGTGGT GACCTTACAA 
CAGTTAAAGT GGTTGGATGG CAAAGAAATA GAACGTTCTG AAAGGATCCA AGCACTGCAG 
AACTACGCAG CAGTTGAACA GCAAATCAGA GAGCAGGAGA AAGCTTACTG CCTTAGACGT 
GCCAAAGAGA AAGAGGAAGC TCAGAGGAAA CTGGAGGAAG AAAACGAAAG TGAAGACAAA 
AAGAAGAGCA GCCCAGGCTT TGATGGGGAT TGTTACACAG ACATCCACGC TGATTGCCCA 
TCTGCCATGG AGAACAAAGA CCATCTTCAG GTACCAGAAA CACAAGAACA ACAACATAGC 
ACAAAGAAAT CAGATGAAAT TGAAGATGAT CTGGCATTCT GGAACAAACC GTCTTTGTTC 
ACTCCTGAAT CTAGATTGGA AACTCTCAGA CACATGGAAA AGCAACGCAA AGCCCAAGAT 
AAGTTAAGTG AAAAGAAAAA AAGAGTGAAA CCACCCCGGA CTTTGATTAC AGAAGATGGG 
AAGGTCCTGA ATGTGAATGA AGCCAAACTT GATTTCTCCT TGAAAGATGA TGAGAAACAC 
AACCAGATCA TCCTGGACCT GGCTGTCTAT AGGTACATGG ACACCTCTTT AATTGAGGTT 
GATGTGCAGC CAACCTATGT TCGAGTAATG GTCAAAGGAA AGCCATTTCA GCTTGCCCTT 
TCTGCAGAGG TCCAGCCTGA CAGCAGCTCT GCTAAAAGGT CTCAGACAAC AGGACATTTG 
CTGATCTGCA TGCCCAAGGT AGGAGAAATG ATCACAGGTC AACAAACACC CATGTCTGTG 
AAGACCGCCT CGGAGAGCAG CAAGGAACAA ACAAAGCCCA GAAGAAAGCA GGTAGAAAGA 
TTAGAAGTTG ATCCCAGCAA GCATTCCTGC CCTGATGTGT CTACTATAGT ACAAGAGAGA 
AAACACAAAC CCAAAAGGAT GGAATCTCAA CCACAAGTTG AACCCAGTGA GGCAGAGCCA 
GACTTTGACG ATAACCCAGA GGTGCCTCCA CTCATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Loss-of-function mutations in LRRC6, a gene essential for proper axonemal assembly of inner and outer dynein arms, cause primary ciliary dyskinesia.
American journal of human genetics91(5)958-64(2012 Nov)
Kott E,Duquesnoy P,Copin B,Legendre M,Dastot-Le Moal F,Montantin G,Jeanson L,Tamalet A,Papon JF,Siffroi JP,Rives N,Mitchell V,de Blic J,Coste A,Clement A,Escalier D,Tour? A,Escudier E,Amselem S

Identification of a novel testis-specific leucine-rich protein in humans and mice.
Biology of reproduction62(5)1278-84(2000 May)
Xue JC,Goldberg E