Sp5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sp5
Entrez Gene ID	296510
Full Name	Sp5 transcription factor
General protein information	Preferred Names Sp5 transcription factor Names transcription factor Sp5 trans-acting transcription factor 5
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106552.1	NP_001100022.1	transcription factor Sp5

Pathways from BioSystems

Homologies

Homo sapiens (human)	SP5	NP_001003845.1
Canis lupus familiaris (dog)	SP5	XP_851518.2
Pan troglodytes (chimpanzee)	SP5	XP_001135769.2
Rattus norvegicus (Norway rat)	Sp5	NP_001100022.1
	SP5	XP_001082704.1
Danio rerio (zebrafish)	sp5a	NP_851304.1
Bos taurus (cattle)	SP5	XP_005202450.1
Mus musculus (house mouse)	Sp5	NP_071880.1
Gallus gallus (chicken)	SP5	NP_001038149.1
Xenopus tropicalis (tropical clawed frog)	sp5	NP_989092.1

Gene Ontology
Bibliography

Related articles in PubMed

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway.
Li W, Wu J, Yang J, Sun S, Chai R, Chen ZY, Li H
Proceedings of the National Academy of Sciences of the United States of America112(1)166-71(2015 Jan)

Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5.
Fujimura N, Vacik T, Machon O, Vlcek C, Scalabrin S, Speth M, Diep D, Krauss S, Kozmik Z
The Journal of biological chemistry282(2)1225-37(2007 Jan)

Sp5, a new member of the Sp1 family, is dynamically expressed during development and genetically interacts with Brachyury.
Harrison SM, Houzelstein D, Dunwoodie SL, Beddington RS
Developmental biology227(2)358-72(2000 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Sp5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sp5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01620	NM_001106552.1 Latest version!	Rattus norvegicus Sp5 transcription factor (Sp5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sp5 ( NM_001106552.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100022.1 Rattus norvegicus Sp5 transcription factor (Sp5), mRNA.

Price & Availability↑

CloneID	ORa01620
Clone ID Related Accession (Same CDS sequence)	NM_001106552.1
Accession Version	NM_001106552.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	transcription factor Sp5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473949.1. On or before Oct 4, 2007 this sequence version replaced XM_001059614.1, XM_231003.3. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGCTG TGGCTGTCCT CCGGAACGAC TCACTGCAGG CCTTCCTCCA GGACCGCACC 
CCCAGCGCCT CCCCGGACCT GGGCAAGCAC TCGCCCCTGG CACTGCTGGC CGCCACCTGT 
AGCCGGATCG GCCAGCCGGG CGCTGCGGCG GCACCCGACT TCCTTCAGGT GCCCTATGAC 
CCAGCTCTGG GTTCACCCTC CAGGCTTTTC CACCCGTGGA CTGCCGACAT GCCCGCGCAC 
TCGCCAGGAG CCCTGCCGCC CCCACACCCC AGCCTGGGGC TGACGCCACA GAAAACACAC 
CTGCAGCCAT CCTTCGGGGC AGCTCACGAG CTCCCGCTCA CTCCCCCCGC GGATCCGTCC 
TACCCTTACG AGTTCTCGCC CGTCAAGATG CTGCCCTCGA GCATGGCGGC TCTGCCAGCC 
AGCTGCGCGC CGGCATACGT GCCCTACGCT GCCCAAGCCG CGTTGCCCCC GGGCTACTCC 
AACCTGCTAC CCCCGCCGCC ACCACCGCCT CCACCGCCCA CCTGCCGCCA GTTGTCCCCC 
GCCCCGGCCC CGGACGACCT CCCCTGGTGG AGCATCCCGC AATCGGGTGC TGGGCCGGGG 
AGCTCCGGGG TTCCAGGGAC CAGCCTCTCC AGCGCCTGTG CCGGGCCTCC CCACGCTCCC 
CGCTTTCCCG CCTCGGCTGC GGCTGCTGCA GCAGCGGCTG CTGCCCTGCA ACGGGGCCTA 
GTGTTGGGCC CGTCGGACTT TGCACAGTAC CAGAGCCAGA TCGCCGCGCT GCTGCAGACC 
AAGGCCCCCC TGGCGGCCAC GGCCAGGAGG TGCCGCCGCT GCCGCTGCCC CAACTGCCAG 
GCAGCTGGCG GTGCCCCCGA GGCGGAGCCG GGCAAAAAGA AGCAACACGT GTGCCACGTG 
CCAGGCTGCG GCAAGGTGTA CGGCAAGACG TCGCACCTGA AGGCGCACCT GCGCTGGCAC 
ACGGGCGAGC GTCCCTTCGT GTGCAATTGG CTCTTCTGCG GCAAGAGCTT CACGCGCTCC 
GACGAGCTGC AGCGGCACCT CCGGACTCAC ACGGGCGAGA AGCGCTTCGC CTGTCCCGAG 
TGCGGCAAAC GCTTCATGCG AAGCGACCAC CTCGCCAAGC ACGTGAAGAC GCACCAAAAT 
AAGAAGCTCA AAGTCGCCGA GGCCGGGGTG AAGCGGGAGA ACCCGCGGGA CCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100022.1
CDS	338..1534
Translation	MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAAPDFLQVPYDPALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPPTCRQLSPAPAPDDLPWWSIPQSGAGPGSSGVPGTSLSSACAGPPHAPRFPASAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKRENPRDL

Target ORF information:

RefSeq Version	NM_001106552.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Sp5 transcription factor (Sp5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106552.1

ORF Insert Sequence:

ATGGCCGCTG TGGCTGTCCT CCGGAACGAC TCACTGCAGG CCTTCCTCCA GGACCGCACC 
CCCAGCGCCT CCCCGGACCT GGGCAAGCAC TCGCCCCTGG CACTGCTGGC CGCCACCTGT 
AGCCGGATCG GCCAGCCGGG CGCTGCGGCG GCACCCGACT TCCTTCAGGT GCCCTATGAC 
CCAGCTCTGG GTTCACCCTC CAGGCTTTTC CACCCGTGGA CTGCCGACAT GCCCGCGCAC 
TCGCCAGGAG CCCTGCCGCC CCCACACCCC AGCCTGGGGC TGACGCCACA GAAAACACAC 
CTGCAGCCAT CCTTCGGGGC AGCTCACGAG CTCCCGCTCA CTCCCCCCGC GGATCCGTCC 
TACCCTTACG AGTTCTCGCC CGTCAAGATG CTGCCCTCGA GCATGGCGGC TCTGCCAGCC 
AGCTGCGCGC CGGCATACGT GCCCTACGCT GCCCAAGCCG CGTTGCCCCC GGGCTACTCC 
AACCTGCTAC CCCCGCCGCC ACCACCGCCT CCACCGCCCA CCTGCCGCCA GTTGTCCCCC 
GCCCCGGCCC CGGACGACCT CCCCTGGTGG AGCATCCCGC AATCGGGTGC TGGGCCGGGG 
AGCTCCGGGG TTCCAGGGAC CAGCCTCTCC AGCGCCTGTG CCGGGCCTCC CCACGCTCCC 
CGCTTTCCCG CCTCGGCTGC GGCTGCTGCA GCAGCGGCTG CTGCCCTGCA ACGGGGCCTA 
GTGTTGGGCC CGTCGGACTT TGCACAGTAC CAGAGCCAGA TCGCCGCGCT GCTGCAGACC 
AAGGCCCCCC TGGCGGCCAC GGCCAGGAGG TGCCGCCGCT GCCGCTGCCC CAACTGCCAG 
GCAGCTGGCG GTGCCCCCGA GGCGGAGCCG GGCAAAAAGA AGCAACACGT GTGCCACGTG 
CCAGGCTGCG GCAAGGTGTA CGGCAAGACG TCGCACCTGA AGGCGCACCT GCGCTGGCAC 
ACGGGCGAGC GTCCCTTCGT GTGCAATTGG CTCTTCTGCG GCAAGAGCTT CACGCGCTCC 
GACGAGCTGC AGCGGCACCT CCGGACTCAC ACGGGCGAGA AGCGCTTCGC CTGTCCCGAG 
TGCGGCAAAC GCTTCATGCG AAGCGACCAC CTCGCCAAGC ACGTGAAGAC GCACCAAAAT 
AAGAAGCTCA AAGTCGCCGA GGCCGGGGTG AAGCGGGAGA ACCCGCGGGA CCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway.
Proceedings of the National Academy of Sciences of the United States of America112(1)166-71(2015 Jan)
Li W,Wu J,Yang J,Sun S,Chai R,Chen ZY,Li H

Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5.
The Journal of biological chemistry282(2)1225-37(2007 Jan)
Fujimura N,Vacik T,Machon O,Vlcek C,Scalabrin S,Speth M,Diep D,Krauss S,Kozmik Z

Sp5, a new member of the Sp1 family, is dynamically expressed during development and genetically interacts with Brachyury.
Developmental biology227(2)358-72(2000 Nov)
Harrison SM,Houzelstein D,Dunwoodie SL,Beddington RS