Epdr1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Epdr1
Entrez Gene ID	291180
Full Name	ependymin related 1
Synonyms	Epdr2,MERP2
General protein information	Preferred Names ependymin related 1 Names mammalian ependymin-related protein 1 MERP-1 ependymin related protein 1 upregulated in colorectal cancer gene 1 protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007625.1	NP_001007626.1	mammalian ependymin-related protein 1 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	EPDR1	XP_005630990.1
Xenopus tropicalis (tropical clawed frog)	epdr1	XP_002939463.1
Bos taurus (cattle)	EPDR1	NP_001095758.1
Rattus norvegicus (Norway rat)	Epdr1	NP_001007626.1
Gallus gallus (chicken)	EPDR1	XP_418830.2
Homo sapiens (human)	EPDR1	NP_060019.2
Pan troglodytes (chimpanzee)	EPDR1	XP_003318311.1
Mus musculus (house mouse)	Epdr1	NP_598826.3
Danio rerio (zebrafish)	epdr1	NP_001002416.1

Gene Ontology
Bibliography

Related articles in PubMed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

Demonstration of lysosomal localization for the mammalian ependymin-related protein using classical approaches combined with a novel density shift method.
Della Valle MC, Sleat DE, Sohar I, Wen T, Pintar JE, Jadot M, Lobel P
The Journal of biological chemistry281(46)35436-45(2006 Nov)

MERP1: a mammalian ependymin-related protein gene differentially expressed in hematopoietic cells.
Gregorio-King CC, McLeod JL, Collier FM, Collier GR, Bolton KA, Van Der Meer GJ, Apostolopoulos J, Kirkland MA
Gene286(2)249-57(2002 Mar)

Identification and characterization of a novel family of mammalian ependymin-related proteins (MERPs) in hematopoietic, nonhematopoietic, and malignant tissues.
Apostolopoulos J, Sparrow RL, McLeod JL, Collier FM, Darcy PK, Slater HR, Ngu C, Gregorio-King CC, Kirkland MA
DNA and cell biology20(10)625-35(2001 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A novel density shift method was used to demonstrate that EPDR resides in the lysosome.
Title: Demonstration of lysosomal localization for the mammalian ependymin-related protein using classical approaches combined with a novel density shift method.

The following Epdr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Epdr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11209	NM_001007625.1 Latest version!	Rattus norvegicus ependymin related 1 (Epdr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Epdr1 ( NM_001007625.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001007626.1 Rattus norvegicus ependymin related 1 (Epdr1), mRNA.

Price & Availability↑

CloneID	ORa11209
Clone ID Related Accession (Same CDS sequence)	NM_001007625.1
Accession Version	NM_001007625.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	mammalian ependymin-related protein 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083701.1. On Nov 29, 2004 this sequence version replaced XM_225426.2. ##Evidence-Data-START## Transcript exon combination :: BC083701.1, CK358562.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCTCACAC GCGCTCCCCG CCGCCTGGTC CAGGGGCCCC GGGAGACCTG GCTGCTTGGC 
GGCCTCTGGG TCTGGATATT GTGCGGCCTG GGGATGGCGG GCTCCCCGGG AACCCCGCAG 
CCATGCCAGG CGCCCCAGCA GTGGGAGGGA CGTCAGGTTC TGTACCAGCA GAGCAGCGGG 
CACAACAGCC GCGCCCTGGT GTCCTACGAT GGTCTCAACC AGCGCGTGCG GGTGCTGGAC 
GAAAGGAAGG CGCTGATCCC CTGCAAGAGA TTATTTGAAT ACATTTTACT CTATAAGGAT 
GGAGTGATGT TTCAGATTGA ACAAGCCACC AAACTGTGTG CAAAGATACC CTTGGCAGAA 
CCCTGGGATC CTCTCGACAT TCCCCAGAAT TCTACCTTTG AAGATCAGTA CTCTATCGGA 
GGGCCTCAGG AGCAGATCAT GGTCCAGGAA TGGTCTGACA GGAGGACAGC CAGATCCTAT 
GAAACCTGGA TTGGCGTTTA TACAGCCAAG GATTGCTACC CGGTCCAGGA GACCTTCATT 
AGGAACTACA CTGTGGTCCT GTCCACTCGG TTCTTTGATG TGCAGTTGGG CATTAAAGAC 
CCCTCTGTGT TCACCCCACC AAGCACGTGC CAGACAGCAC AGCCAGAGAA GATGAAAGAG 
AACTGCTCCC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007626.1
CDS	219..893
Translation	MLTRAPRRLVQGPRETWLLGGLWVWILCGLGMAGSPGTPQPCQAPQQWEGRQVLYQQSSGHNSRALVSYDGLNQRVRVLDERKALIPCKRLFEYILLYKDGVMFQIEQATKLCAKIPLAEPWDPLDIPQNSTFEDQYSIGGPQEQIMVQEWSDRRTARSYETWIGVYTAKDCYPVQETFIRNYTVVLSTRFFDVQLGIKDPSVFTPPSTCQTAQPEKMKENCSL

Target ORF information:

RefSeq Version	NM_001007625.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ependymin related 1 (Epdr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007625.1

ORF Insert Sequence:

ATGCTCACAC GCGCTCCCCG CCGCCTGGTC CAGGGGCCCC GGGAGACCTG GCTGCTTGGC 
GGCCTCTGGG TCTGGATATT GTGCGGCCTG GGGATGGCGG GCTCCCCGGG AACCCCGCAG 
CCATGCCAGG CGCCCCAGCA GTGGGAGGGA CGTCAGGTTC TGTACCAGCA GAGCAGCGGG 
CACAACAGCC GCGCCCTGGT GTCCTACGAT GGTCTCAACC AGCGCGTGCG GGTGCTGGAC 
GAAAGGAAGG CGCTGATCCC CTGCAAGAGA TTATTTGAAT ACATTTTACT CTATAAGGAT 
GGAGTGATGT TTCAGATTGA ACAAGCCACC AAACTGTGTG CAAAGATACC CTTGGCAGAA 
CCCTGGGATC CTCTCGACAT TCCCCAGAAT TCTACCTTTG AAGATCAGTA CTCTATCGGA 
GGGCCTCAGG AGCAGATCAT GGTCCAGGAA TGGTCTGACA GGAGGACAGC CAGATCCTAT 
GAAACCTGGA TTGGCGTTTA TACAGCCAAG GATTGCTACC CGGTCCAGGA GACCTTCATT 
AGGAACTACA CTGTGGTCCT GTCCACTCGG TTCTTTGATG TGCAGTTGGG CATTAAAGAC 
CCCTCTGTGT TCACCCCACC AAGCACGTGC CAGACAGCAC AGCCAGAGAA GATGAAAGAG 
AACTGCTCCC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

Demonstration of lysosomal localization for the mammalian ependymin-related protein using classical approaches combined with a novel density shift method.
The Journal of biological chemistry281(46)35436-45(2006 Nov)
Della Valle MC,Sleat DE,Sohar I,Wen T,Pintar JE,Jadot M,Lobel P

MERP1: a mammalian ependymin-related protein gene differentially expressed in hematopoietic cells.
Gene286(2)249-57(2002 Mar)
Gregorio-King CC,McLeod JL,Collier FM,Collier GR,Bolton KA,Van Der Meer GJ,Apostolopoulos J,Kirkland MA

Identification and characterization of a novel family of mammalian ependymin-related proteins (MERPs) in hematopoietic, nonhematopoietic, and malignant tissues.
DNA and cell biology20(10)625-35(2001 Oct)
Apostolopoulos J,Sparrow RL,McLeod JL,Collier FM,Darcy PK,Slater HR,Ngu C,Gregorio-King CC,Kirkland MA