| Gene Symbol | TP-1P8 |
| Entrez Gene ID | 100144751 |
| Full Name | ovine trophoblast protein-1 p8 |
| Synonyms | IFN-tau2,IFNT2,TP-1 |
| Gene Type | protein-coding |
| Organism | Ovis aries(sheep) |
ORF » Species Summary » Ovis aries » TP-1P8 cDNA ORF clone
| Gene Symbol | TP-1P8 |
| Entrez Gene ID | 100144751 |
| Full Name | ovine trophoblast protein-1 p8 |
| Synonyms | IFN-tau2,IFNT2,TP-1 |
| Gene Type | protein-coding |
| Organism | Ovis aries(sheep) |
| mRNA | Protein | Name |
|---|---|---|
| NM_001123400.1 | NP_001116872.1 | interferon tau-2 precursor |
Endometrial HSD11B1 and cortisol regeneration in the ovine uterus: effects of pregnancy, interferon tau, and prostaglandins.
Dorniak P, Welsh TH Jr, Bazer FW, Spencer TE
Biology of reproduction86(4)124(2012 Apr)
Expression of interferon (IFN)-stimulated genes in extrauterine tissues during early pregnancy in sheep is the consequence of endocrine IFN-tau release from the uterine vein.
Oliveira JF, Henkes LE, Ashley RL, Purcell SH, Smirnova NP, Veeramachaneni DN, Anthony RV, Hansen TR
Endocrinology149(3)1252-9(2008 Mar)
Identification of endometrial genes regulated by early pregnancy, progesterone, and interferon tau in the ovine uterus.
Gray CA, Abbey CA, Beremand PD, Choi Y, Farmer JL, Adelson DL, Thomas TL, Bazer FW, Spencer TE
Biology of reproduction74(2)383-94(2006 Feb)
IFN-tau: a novel subtype I IFN1. Structural characteristics, non-ubiquitous expression, structure-function relationships, a pregnancy hormonal embryonic signal and cross-species therapeutic potentialities.
Martal JL, Ch?ne NM, Huynh LP, L'Haridon RM, Reinaud PB, Guillomot MW, Charlier MA, Charpigny SY
Biochimie80(8-9)755-77(1998 Aug-Sep)
A three-dimensional model of interferon-tau.
Senda T, Saitoh SI, Mitsui Y, Li J, Roberts RM
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research15(12)1053-60(1995 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
studies support the idea that trophoblastin and prostaglandinss from the conceptus regulate endometrial HSD11B1 expression and activity that regenerates bioactive cortisol in the ovine uterus during early pregnancy
Title: Endometrial HSD11B1 and cortisol regeneration in the ovine uterus: effects of pregnancy, interferon tau, and prostaglandins.
Uterine vein releases IFN-tau, which induces ISG15 and OAS-1 in extrauterine tissues such as the corpus luteum during the time of maternal recognition of pregnancy.
Title: Expression of interferon (IFN)-stimulated genes in extrauterine tissues during early pregnancy in sheep is the consequence of endocrine IFN-tau release from the uterine vein.
74 genes were affected by IFNT in a progesterone-dependent manner, and 180 genes were regulated by IFNT in a progesterone-independent manner in endometrium during pregnancy [IFNT interferon tau ]
Title: Identification of endometrial genes regulated by early pregnancy, progesterone, and interferon tau in the ovine uterus.
The following TP-1P8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TP-1P8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSm00215 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001123400.1 | |
| Accession Version | NM_001123400.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-21 | |
| Organism | Ovis aries(sheep) | |
| Product | interferon tau-2 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M26386.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M26386.1 [ECO:0000332] ##Evidence-Data-END## | |
1 | ATGGCCTTCG TGCTCTCTCT ACTGATGGCC CTGGTGCTGG TCAGCTATGG CCCAGGAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001116872.1 |
| CDS | 68..655 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001123400.1 |
1 | ATGGCCTTCG TGCTCTCTCT ACTGATGGCC CTGGTGCTGG TCAGCTATGG CCCAGGAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Endometrial HSD11B1 and cortisol regeneration in the ovine uterus: effects of pregnancy, interferon tau, and prostaglandins. |
Expression of interferon (IFN)-stimulated genes in extrauterine tissues during early pregnancy in sheep is the consequence of endocrine IFN-tau release from the uterine vein. |
Identification of endometrial genes regulated by early pregnancy, progesterone, and interferon tau in the ovine uterus. |
IFN-tau: a novel subtype I IFN1. Structural characteristics, non-ubiquitous expression, structure-function relationships, a pregnancy hormonal embryonic signal and cross-species therapeutic potentialities. |
A three-dimensional model of interferon-tau. |