Defb43 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Defb43
Entrez Gene ID	654458
Full Name	defensin beta 43
Synonyms	BD-43,EG654458,mBD-43
General protein information	Preferred Names defensin beta 43 Names beta-defensin 43
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14 D1\|14

mRNA and Protein(s)

mRNA	Protein	Name
NM_001039121.1	NP_001034210.1	beta-defensin 43 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Defb43	NP_001032617.1
Mus musculus (house mouse)	Defb43	NP_001034210.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
Patil AA, Cai Y, Sang Y, Blecha F, Zhang G
Physiological genomics23(1)5-17(2005 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Defb43 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Defb43 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00440	NM_001039121.1 Latest version!	Mus musculus defensin beta 43 (Defb43), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Defb43 ( NM_001039121.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001034210.1 Mus musculus defensin beta 43 (Defb43), mRNA.

Price & Availability↑

CloneID	OMu00440
Clone ID Related Accession (Same CDS sequence)	NM_001039121.1
Accession Version	NM_001039121.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 210bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-19
Organism	Mus musculus(house mouse)
Product	beta-defensin 43 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DQ012045.1. ##Evidence-Data-START## Transcript exon combination :: DQ012045.1, BC132224.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGAGGGTCC TGTTCTCCAT CCTGGGGGTC CTCACCTTGT TATCCATAGT TCCTCTGGCC 
AGGAGCTTCC TTGAGAATCA GGACTGTTCA AAGCACCGCC ACTGCAGGAT GAAGTGCAAA 
GCTAACGAAT ACGCCGTCAG ATACTGCGAG GACTGGACCA TCTGCTGTCG GGTGAAGAAG 
AAGGAATCCA AGAAGAAGAA GATGTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034210.1
CDS	40..249
Translation	MRVLFSILGVLTLLSIVPLARSFLENQDCSKHRHCRMKCKANEYAVRYCEDWTICCRVKKKESKKKKMW

Target ORF information:

RefSeq Version	NM_001039121.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus defensin beta 43 (Defb43), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039121.1

ORF Insert Sequence:

ATGAGGGTCC TGTTCTCCAT CCTGGGGGTC CTCACCTTGT TATCCATAGT TCCTCTGGCC 
AGGAGCTTCC TTGAGAATCA GGACTGTTCA AAGCACCGCC ACTGCAGGAT GAAGTGCAAA 
GCTAACGAAT ACGCCGTCAG ATACTGCGAG GACTGGACCA TCTGCTGTCG GGTGAAGAAG 
AAGGAATCCA AGAAGAAGAA GATGTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
Physiological genomics23(1)5-17(2005 Sep)
Patil AA,Cai Y,Sang Y,Blecha F,Zhang G