S100a2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	S100a2
Entrez Gene ID	628324
Full Name	S100 calcium binding protein A2
Synonyms	CaN19,EG628324,S100L
General protein information	Preferred Names S100 calcium binding protein A2 Names predicted gene, EG628324
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3\|3 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001195760.1	NP_001182689.1	predicted gene, EG628324

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	S100a2	NP_001182689.1
Rattus norvegicus (Norway rat)	LOC100910139	XP_003749376.1

Gene Ontology
Bibliography

Related articles in PubMed

Transgenic expression of S100A2 in hairless mouse skin enhances Cxcl13 mRNA in response to solar-simulated radiation.
Li Y, Gudjonsson JE, Woods TL, Zhang T, Johnston A, Stoll SW, Elder JT
Archives of dermatological research301(3)205-17(2009 Mar)

Interactions of S100A2 and S100A6 with the tetratricopeptide repeat proteins, Hsp90/Hsp70-organizing protein and kinesin light chain.
Shimamoto S, Takata M, Tokuda M, Oohira F, Tokumitsu H, Kobayashi R
The Journal of biological chemistry283(42)28246-58(2008 Oct)

An update of the S100 nomenclature.
Marenholz I, Lovering RC, Heizmann CW
Biochimica et biophysica acta1763(11)1282-3(2006 Nov)

S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature).
Marenholz I, Heizmann CW, Fritz G
Biochemical and biophysical research communications322(4)1111-22(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Survival after UVA irradiation was greater in human keratinocytes compared to mouse skin with no S100A2 expression, showing a protective role for S100A2. A S100A2-dependent difference was observed in the induction of Cxcl13 transcripts in transgenic mice.
Title: Transgenic expression of S100A2 in hairless mouse skin enhances Cxcl13 mRNA in response to solar-simulated radiation.

S100A2 and S100A6 interact with another TPR protein Tom70 and regulate the Tom70-ligand interaction in vitro
Title: Interactions of S100A2 and S100A6 with the tetratricopeptide repeat proteins, Hsp90/Hsp70-organizing protein and kinesin light chain.

The following S100a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the S100a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu23824	NM_001195760.1 Latest version!	Mus musculus S100 calcium binding protein A2 (S100a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

S100a2 ( NM_001195760.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001182689.1 Mus musculus S100 calcium binding protein A2 (S100a2), mRNA.

Price & Availability↑

CloneID	OMu23824
Clone ID Related Accession (Same CDS sequence)	NM_001195760.1
Accession Version	NM_001195760.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 315bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-25
Organism	Mus musculus(house mouse)
Product	predicted gene, EG628324
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC160552.13. On Sep 25, 2010 this sequence version replaced XM_001478157.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

ATGGTCTATA CCTTCCACAA GTACGCCAGT CAAGAGGACG AGAGGCTCAA ACACAACAAA 
GGGGAGATAA AGGAGCTTTT GCGTAAGGAG CTGCTGAGCT ATGTGGGGGA TAACGTAGAT 
GATGAGAAGG TGAAGAAGGA AATGAACAAC CTCGATAAGG ACAGTGACCA GCAGGTGGAC 
TTCCGGATGT ATGCCCTGGT TCTGGTGGAT TCTGCTATCT GGTTTAATAA CTTCCTTGAG 
GGGTCCCCAG CGCTCCACTA CCTGCCGTGG ATCTCTTGGT TGAAACAACT CTCTATCTTT 
TTAAGTTTGT ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001182689.1
CDS	1..315
Translation	MVYTFHKYASQEDERLKHNKGEIKELLRKELLSYVGDNVDDEKVKKEMNNLDKDSDQQVDFRMYALVLVDSAIWFNNFLEGSPALHYLPWISWLKQLSIFLSLY

Target ORF information:

RefSeq Version	NM_001195760.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus S100 calcium binding protein A2 (S100a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001195760.1

ORF Insert Sequence:

ATGGTCTATA CCTTCCACAA GTACGCCAGT CAAGAGGACG AGAGGCTCAA ACACAACAAA 
GGGGAGATAA AGGAGCTTTT GCGTAAGGAG CTGCTGAGCT ATGTGGGGGA TAACGTAGAT 
GATGAGAAGG TGAAGAAGGA AATGAACAAC CTCGATAAGG ACAGTGACCA GCAGGTGGAC 
TTCCGGATGT ATGCCCTGGT TCTGGTGGAT TCTGCTATCT GGTTTAATAA CTTCCTTGAG 
GGGTCCCCAG CGCTCCACTA CCTGCCGTGG ATCTCTTGGT TGAAACAACT CTCTATCTTT 
TTAAGTTTGT ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transgenic expression of S100A2 in hairless mouse skin enhances Cxcl13 mRNA in response to solar-simulated radiation.
Archives of dermatological research301(3)205-17(2009 Mar)
Li Y,Gudjonsson JE,Woods TL,Zhang T,Johnston A,Stoll SW,Elder JT

Interactions of S100A2 and S100A6 with the tetratricopeptide repeat proteins, Hsp90/Hsp70-organizing protein and kinesin light chain.
The Journal of biological chemistry283(42)28246-58(2008 Oct)
Shimamoto S,Takata M,Tokuda M,Oohira F,Tokumitsu H,Kobayashi R

An update of the S100 nomenclature.
Biochimica et biophysica acta1763(11)1282-3(2006 Nov)
Marenholz I,Lovering RC,Heizmann CW

S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature).
Biochemical and biophysical research communications322(4)1111-22(2004 Oct)
Marenholz I,Heizmann CW,Fritz G