Camk1 cDNA ORF clone, Mus musculus(house mouse)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Excitation-Transcription Coupling in Parvalbumin-Positive Interneurons Employs a Novel CaM Kinase-Dependent Pathway Distinct from Excitatory Neurons.
Cohen SM, Ma H, Kuchibhotla KV, Watson BO, Buzs?ki G, Froemke RC, Tsien RW
Neuron90(2)292-307(2016 04)

Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKI? pathway during neuronal polarization.
Horigane S, Ageta-Ishihara N, Kamijo S, Fujii H, Okamura M, Kinoshita M, Takemoto-Kimura S, Bito H
Molecular brain98(2016 Jan)

The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development.
Kang X, Lu Z, Cui C, Deng M, Fan Y, Dong B, Han X, Xie F, Tyner JW, Coligan JE, Collins RH, Xiao X, You MJ, Zhang CC
Nature cell biology17(5)665-77(2015 May)

report that Parvalbumin positive interneurons employ a novel CaMK-dependent pathway to trigger CREB phosphorylation and gene expression.
Title: Excitation-Transcription Coupling in Parvalbumin-Positive Interneurons Employs a Novel CaM Kinase-Dependent Pathway Distinct from Excitatory Neurons.

the CaMKK-CaMKIalpha cascade is required for the axonal growth effect of Wnt5a during neuronal polarization.
Title: Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKI? pathway during neuronal polarization.

CaMKIalpha regulates AMP kinase-dependent, TORC-1-independent autophagy during lipopolysaccharide-induced acute lung neutrophilic inflammation.
Title: CaMKI? regulates AMP kinase-dependent, TORC-1-independent autophagy during lipopolysaccharide-induced acute lung neutrophilic inflammation.

CaMKI vies with CRM1/exportin 1 for access to a nuclear export signal, and assembly of a CaMKI-14-3-3 zeta-CCTalpha complex is a key effector mechanism that drives nuclear CCTalpha translocation.
Title: Calcium-calmodulin kinase I cooperatively regulates nucleocytoplasmic shuttling of CCT? by accessing a nuclear export signal.

CaMKIalpha signaling is integral to the Mvarphi responding to LPS and may also be operant in vivo in regulating the inflammation and organ dysfunction consequent to sepsis.
Title: Calcium/calmodulin-dependent protein kinase (CaMK) Ialpha mediates the macrophage inflammatory response to sepsis.