Lypd6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lypd6
Entrez Gene ID	320343
Full Name	LY6/PLAUR domain containing 6
Synonyms	E130115E03Rik
General protein information	Preferred Names LY6/PLAUR domain containing 6 Names ly6/PLAUR domain-containing protein 6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 C1.1

mRNA and Protein(s)

mRNA	Protein	Name
XM_011239116.2	XP_011237418.1	ly6/PLAUR domain-containing protein 6 isoform X1
NM_177139.5	NP_796113.1	ly6/PLAUR domain-containing protein 6 precursor
XM_011239116.1	XP_011237418.1	ly6/PLAUR domain-containing protein 6 isoform X1
XM_011239116.3	XP_011237418.1	ly6/PLAUR domain-containing protein 6 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LYPD6	XP_002685433.1
Canis lupus familiaris (dog)	LYPD6	XP_850653.1
Homo sapiens (human)	LYPD6	NP_001182614.1
Gallus gallus (chicken)	LYPD6	XP_001234906.1
Pan troglodytes (chimpanzee)	LYPD6	XP_001134811.1
	LYPD6	XP_002798923.1
Mus musculus (house mouse)	Lypd6	NP_796113.1
Rattus norvegicus (Norway rat)	Lypd6	XP_001053512.3
Danio rerio (zebrafish)	lypd6	NP_001004670.1
Xenopus tropicalis (tropical clawed frog)	lypd6	NP_001106503.1

Gene Ontology
Bibliography

Related articles in PubMed

Loss of Lypd6 leads to reduced anxiety-like behaviour and enhanced responses to nicotine.
Arvaniti M, Polli FS, Kohlmeier KA, Thomsen MS, Andreasen JT
Progress in neuro-psychopharmacology & biological psychiatry(2017 Nov)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Organization, evolution and functions of the human and mouse Ly6/uPAR family genes.
Loughner CL, Bruford EA, McAndrews MS, Delp EE, Swamynathan S, Swamynathan SK
Human genomics1010(2016 Apr)

Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA
Developmental biology406(1)92-103(2015 Oct)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Lypd6 appears to control Lrp6 activation specifically in membrane rafts, which is essential for downstream signaling.
Title: Lypd6 enhances Wnt/?-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains.

Lypd6 seems to constitute a novel modulator of nAChRs that affects receptor function by selectively increasing Ca2+-influx through ion channels
Title: Modulation of the Ca2+ conductance of nicotinic acetylcholine receptors by Lypd6.

The following Lypd6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lypd6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05971	NM_177139.5 Latest version!	Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu05971	XM_011239116.3 Latest version!	Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu05971	XM_011239116.1	Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu05971	XM_011239116.2	Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lypd6 ( NM_177139.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_796113.1 Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu05971
Clone ID Related Accession (Same CDS sequence)	XM_011239116.2 , NM_177139.5 , XM_011239116.1 , XM_011239116.3
Accession Version	NM_177139.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	ly6/PLAUR domain-containing protein 6 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL806528.14, BB653059.1, BC070462.1 and AW547599.2. On Aug 9, 2011 this sequence version replaced NM_177139.4. Transcript Variant: This variant (1) represents the shorter transcript and encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BB619054.1, CN663979.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAACCTA GCCCTGCCCT GGCCTGGCTC CTACTGCTGA GCCTGGTGGC TGATTGTCTG 
AAGGCTGCTC AGTCCCGAGA CTTCACAGTG AAAGACATAA TCTACCTCCA CCCTTCAACC 
ACTCCGTATC CTGGTGGGTT TAAGTGTTTC ACCTGTGAGA AAGCAGCAGA CAATTATGAA 
TGCAACCGAT GGGCTCCTGA CATCTACTGT CCTCGAGACA CCAGATACTG CTACACTCAG 
CACACGATGG AAGTCACAGG GAACAGCATC TCTGTCACCA AACGCTGTGT CCCGCTGGAG 
GAGTGCTTAT CCACAGGCTG CCGAGACTCA GAGCACGAAG GCTACAAGAT CTGCACCTCC 
TGCTGTGAAG GAAATATCTG TAATCTACCA CTCCCTCGAA ATGAAACTGA TGCCACATTT 
GCTACCACAT CACCTATAAA CCAGACGAAT GGGCACCCAC ACTGTGTTTC AGTGATCGTG 
TCCTGCTTGT GGGTGTGGCT GGGACTCACC TTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_796113.1
CDS	228..743
Translation	MEPSPALAWLLLLSLVADCLKAAQSRDFTVKDIIYLHPSTTPYPGGFKCFTCEKAADNYECNRWAPDIYCPRDTRYCYTQHTMEVTGNSISVTKRCVPLEECLSTGCRDSEHEGYKICTSCCEGNICNLPLPRNETDATFATTSPINQTNGHPHCVSVIVSCLWVWLGLTL

Target ORF information:

RefSeq Version	NM_177139.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177139.5

ORF Insert Sequence:

ATGGAACCTA GCCCTGCCCT GGCCTGGCTC CTACTGCTGA GCCTGGTGGC TGATTGTCTG 
AAGGCTGCTC AGTCCCGAGA CTTCACAGTG AAAGACATAA TCTACCTCCA CCCTTCAACC 
ACTCCGTATC CTGGTGGGTT TAAGTGTTTC ACCTGTGAGA AAGCAGCAGA CAATTATGAA 
TGCAACCGAT GGGCTCCTGA CATCTACTGT CCTCGAGACA CCAGATACTG CTACACTCAG 
CACACGATGG AAGTCACAGG GAACAGCATC TCTGTCACCA AACGCTGTGT CCCGCTGGAG 
GAGTGCTTAT CCACAGGCTG CCGAGACTCA GAGCACGAAG GCTACAAGAT CTGCACCTCC 
TGCTGTGAAG GAAATATCTG TAATCTACCA CTCCCTCGAA ATGAAACTGA TGCCACATTT 
GCTACCACAT CACCTATAAA CCAGACGAAT GGGCACCCAC ACTGTGTTTC AGTGATCGTG 
TCCTGCTTGT GGGTGTGGCT GGGACTCACC TTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lypd6 ( XM_011239116.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011237418.1 Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu05971
Clone ID Related Accession (Same CDS sequence)	XM_011239116.2 , NM_177139.5 , XM_011239116.1 , XM_011239116.3
Accession Version	XM_011239116.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	ly6/PLAUR domain-containing protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011239116.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACCTA GCCCTGCCCT GGCCTGGCTC CTACTGCTGA GCCTGGTGGC TGATTGTCTG 
AAGGCTGCTC AGTCCCGAGA CTTCACAGTG AAAGACATAA TCTACCTCCA CCCTTCAACC 
ACTCCGTATC CTGGTGGGTT TAAGTGTTTC ACCTGTGAGA AAGCAGCAGA CAATTATGAA 
TGCAACCGAT GGGCTCCTGA CATCTACTGT CCTCGAGACA CCAGATACTG CTACACTCAG 
CACACGATGG AAGTCACAGG GAACAGCATC TCTGTCACCA AACGCTGTGT CCCGCTGGAG 
GAGTGCTTAT CCACAGGCTG CCGAGACTCA GAGCACGAAG GCTACAAGAT CTGCACCTCC 
TGCTGTGAAG GAAATATCTG TAATCTACCA CTCCCTCGAA ATGAAACTGA TGCCACATTT 
GCTACCACAT CACCTATAAA CCAGACGAAT GGGCACCCAC ACTGTGTTTC AGTGATCGTG 
TCCTGCTTGT GGGTGTGGCT GGGACTCACC TTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011237418.1
CDS	210..725
Translation	MEPSPALAWLLLLSLVADCLKAAQSRDFTVKDIIYLHPSTTPYPGGFKCFTCEKAADNYECNRWAPDIYCPRDTRYCYTQHTMEVTGNSISVTKRCVPLEECLSTGCRDSEHEGYKICTSCCEGNICNLPLPRNETDATFATTSPINQTNGHPHCVSVIVSCLWVWLGLTL

Target ORF information:

RefSeq Version	XM_011239116.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011239116.2

ORF Insert Sequence:

ATGGAACCTA GCCCTGCCCT GGCCTGGCTC CTACTGCTGA GCCTGGTGGC TGATTGTCTG 
AAGGCTGCTC AGTCCCGAGA CTTCACAGTG AAAGACATAA TCTACCTCCA CCCTTCAACC 
ACTCCGTATC CTGGTGGGTT TAAGTGTTTC ACCTGTGAGA AAGCAGCAGA CAATTATGAA 
TGCAACCGAT GGGCTCCTGA CATCTACTGT CCTCGAGACA CCAGATACTG CTACACTCAG 
CACACGATGG AAGTCACAGG GAACAGCATC TCTGTCACCA AACGCTGTGT CCCGCTGGAG 
GAGTGCTTAT CCACAGGCTG CCGAGACTCA GAGCACGAAG GCTACAAGAT CTGCACCTCC 
TGCTGTGAAG GAAATATCTG TAATCTACCA CTCCCTCGAA ATGAAACTGA TGCCACATTT 
GCTACCACAT CACCTATAAA CCAGACGAAT GGGCACCCAC ACTGTGTTTC AGTGATCGTG 
TCCTGCTTGT GGGTGTGGCT GGGACTCACC TTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lypd6 ( XM_011239116.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011237418.1 Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu05971
Clone ID Related Accession (Same CDS sequence)	XM_011239116.2 , NM_177139.5 , XM_011239116.1 , XM_011239116.3
Accession Version	XM_011239116.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	ly6/PLAUR domain-containing protein 6 isoform X1
Comment

ATGGAACCTA GCCCTGCCCT GGCCTGGCTC CTACTGCTGA GCCTGGTGGC TGATTGTCTG 
AAGGCTGCTC AGTCCCGAGA CTTCACAGTG AAAGACATAA TCTACCTCCA CCCTTCAACC 
ACTCCGTATC CTGGTGGGTT TAAGTGTTTC ACCTGTGAGA AAGCAGCAGA CAATTATGAA 
TGCAACCGAT GGGCTCCTGA CATCTACTGT CCTCGAGACA CCAGATACTG CTACACTCAG 
CACACGATGG AAGTCACAGG GAACAGCATC TCTGTCACCA AACGCTGTGT CCCGCTGGAG 
GAGTGCTTAT CCACAGGCTG CCGAGACTCA GAGCACGAAG GCTACAAGAT CTGCACCTCC 
TGCTGTGAAG GAAATATCTG TAATCTACCA CTCCCTCGAA ATGAAACTGA TGCCACATTT 
GCTACCACAT CACCTATAAA CCAGACGAAT GGGCACCCAC ACTGTGTTTC AGTGATCGTG 
TCCTGCTTGT GGGTGTGGCT GGGACTCACC TTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011237418.1
Translation	MEPSPALAWLLLLSLVADCLKAAQSRDFTVKDIIYLHPSTTPYPGGFKCFTCEKAADNYECNRWAPDIYCPRDTRYCYTQHTMEVTGNSISVTKRCVPLEECLSTGCRDSEHEGYKICTSCCEGNICNLPLPRNETDATFATTSPINQTNGHPHCVSVIVSCLWVWLGLTL

Target ORF information:

RefSeq Version	XM_011239116.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011239116.1

ORF Insert Sequence:

ATGGAACCTA GCCCTGCCCT GGCCTGGCTC CTACTGCTGA GCCTGGTGGC TGATTGTCTG 
AAGGCTGCTC AGTCCCGAGA CTTCACAGTG AAAGACATAA TCTACCTCCA CCCTTCAACC 
ACTCCGTATC CTGGTGGGTT TAAGTGTTTC ACCTGTGAGA AAGCAGCAGA CAATTATGAA 
TGCAACCGAT GGGCTCCTGA CATCTACTGT CCTCGAGACA CCAGATACTG CTACACTCAG 
CACACGATGG AAGTCACAGG GAACAGCATC TCTGTCACCA AACGCTGTGT CCCGCTGGAG 
GAGTGCTTAT CCACAGGCTG CCGAGACTCA GAGCACGAAG GCTACAAGAT CTGCACCTCC 
TGCTGTGAAG GAAATATCTG TAATCTACCA CTCCCTCGAA ATGAAACTGA TGCCACATTT 
GCTACCACAT CACCTATAAA CCAGACGAAT GGGCACCCAC ACTGTGTTTC AGTGATCGTG 
TCCTGCTTGT GGGTGTGGCT GGGACTCACC TTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lypd6 ( XM_011239116.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011237418.1 Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu05971
Clone ID Related Accession (Same CDS sequence)	XM_011239116.2 , NM_177139.5 , XM_011239116.1 , XM_011239116.3
Accession Version	XM_011239116.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ly6/PLAUR domain-containing protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011239116.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACCTA GCCCTGCCCT GGCCTGGCTC CTACTGCTGA GCCTGGTGGC TGATTGTCTG 
AAGGCTGCTC AGTCCCGAGA CTTCACAGTG AAAGACATAA TCTACCTCCA CCCTTCAACC 
ACTCCGTATC CTGGTGGGTT TAAGTGTTTC ACCTGTGAGA AAGCAGCAGA CAATTATGAA 
TGCAACCGAT GGGCTCCTGA CATCTACTGT CCTCGAGACA CCAGATACTG CTACACTCAG 
CACACGATGG AAGTCACAGG GAACAGCATC TCTGTCACCA AACGCTGTGT CCCGCTGGAG 
GAGTGCTTAT CCACAGGCTG CCGAGACTCA GAGCACGAAG GCTACAAGAT CTGCACCTCC 
TGCTGTGAAG GAAATATCTG TAATCTACCA CTCCCTCGAA ATGAAACTGA TGCCACATTT 
GCTACCACAT CACCTATAAA CCAGACGAAT GGGCACCCAC ACTGTGTTTC AGTGATCGTG 
TCCTGCTTGT GGGTGTGGCT GGGACTCACC TTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011237418.1
CDS	355..870
Translation	MEPSPALAWLLLLSLVADCLKAAQSRDFTVKDIIYLHPSTTPYPGGFKCFTCEKAADNYECNRWAPDIYCPRDTRYCYTQHTMEVTGNSISVTKRCVPLEECLSTGCRDSEHEGYKICTSCCEGNICNLPLPRNETDATFATTSPINQTNGHPHCVSVIVSCLWVWLGLTL

Target ORF information:

RefSeq Version	XM_011239116.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus LY6/PLAUR domain containing 6 (Lypd6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011239116.3

ORF Insert Sequence:

ATGGAACCTA GCCCTGCCCT GGCCTGGCTC CTACTGCTGA GCCTGGTGGC TGATTGTCTG 
AAGGCTGCTC AGTCCCGAGA CTTCACAGTG AAAGACATAA TCTACCTCCA CCCTTCAACC 
ACTCCGTATC CTGGTGGGTT TAAGTGTTTC ACCTGTGAGA AAGCAGCAGA CAATTATGAA 
TGCAACCGAT GGGCTCCTGA CATCTACTGT CCTCGAGACA CCAGATACTG CTACACTCAG 
CACACGATGG AAGTCACAGG GAACAGCATC TCTGTCACCA AACGCTGTGT CCCGCTGGAG 
GAGTGCTTAT CCACAGGCTG CCGAGACTCA GAGCACGAAG GCTACAAGAT CTGCACCTCC 
TGCTGTGAAG GAAATATCTG TAATCTACCA CTCCCTCGAA ATGAAACTGA TGCCACATTT 
GCTACCACAT CACCTATAAA CCAGACGAAT GGGCACCCAC ACTGTGTTTC AGTGATCGTG 
TCCTGCTTGT GGGTGTGGCT GGGACTCACC TTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Loss of Lypd6 leads to reduced anxiety-like behaviour and enhanced responses to nicotine.
Progress in neuro-psychopharmacology & biological psychiatry(2017 Nov)
Arvaniti M,Polli FS,Kohlmeier KA,Thomsen MS,Andreasen JT

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Organization, evolution and functions of the human and mouse Ly6/uPAR family genes.
Human genomics1010(2016 Apr)
Loughner CL,Bruford EA,McAndrews MS,Delp EE,Swamynathan S,Swamynathan SK

Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Developmental biology406(1)92-103(2015 Oct)
Lewandowski JP,Du F,Zhang S,Powell MB,Falkenstein KN,Ji H,Vokes SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

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Lypd6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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