Srpk1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Srpk1
Entrez Gene ID	20815
Full Name	serine/arginine-rich protein specific kinase 1
Synonyms	AU017960
General protein information	Preferred Names serine/arginine-rich protein specific kinase 1 Names SRSF protein kinase 1 SFRS protein kinase 1 SR-protein-specific kinase 1 serine/threonine-protein kinase SRPK1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17\|17 A3.3

mRNA and Protein(s)

mRNA	Protein	Name
XM_011246337.3	XP_011244639.1	SRSF protein kinase 1 isoform X2
NM_016795.4	NP_058075.2	SRSF protein kinase 1
XM_006523958.3	XP_006524021.1	SRSF protein kinase 1 isoform X1
XM_011246337.2	XP_011244639.1	SRSF protein kinase 1 isoform X2
XM_006523958.4	XP_006524021.1	SRSF protein kinase 1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SRPK1	XP_001172595.2
Bos taurus (cattle)	SRPK1	XP_002697249.2
Rattus norvegicus (Norway rat)	Srpk1	NP_001020897.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005322	XP_315336.4
Oryza sativa (rice)	Os03g0748400	NP_001051268.2
Gallus gallus (chicken)	SRPK1	XP_419265.4
Danio rerio (zebrafish)	srpk1b	NP_001074138.1
	SRPK1	XP_001116721.2
Mus musculus (house mouse)	Srpk1	NP_058075.2
Danio rerio (zebrafish)	srpk1a	NP_955944.1
Homo sapiens (human)	SRPK1	NP_003128.3
Drosophila melanogaster (fruit fly)	SRPK	NP_725458.1
Xenopus tropicalis (tropical clawed frog)	srpk1	NP_001017351.1
Canis lupus familiaris (dog)	SRPK1	XP_005627322.1
Arabidopsis thaliana (thale cress)	AT5G22840	NP_197675.1
Arabidopsis thaliana (thale cress)	AT3G44850	NP_190071.1
Arabidopsis thaliana (thale cress)	SRPK4	NP_566977.1

Gene Ontology
Bibliography

Related articles in PubMed

Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant.
van Roosmalen W, Le D?v?dec SE, Golani O, Smid M, Pulyakhina I, Timmermans AM, Look MP, Zi D, Pont C, de Graauw M, Naffar-Abu-Amara S, Kirsanova C, Rustici G, Hoen PA, Martens JW, Foekens JA, Geiger B, van de Water B
The Journal of clinical investigation125(4)1648-64(2015 Apr)

Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.
Wang P, Zhou Z, Hu A, Ponte de Albuquerque C, Zhou Y, Hong L, Sierecki E, Ajiro M, Kruhlak M, Harris C, Guan KL, Zheng ZM, Newton AC, Sun P, Zhou H, Fu XD
Molecular cell54(3)378-91(2014 May)

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ
PLoS genetics5(6)e1000511(2009 Jun)

Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2.
Nakagawa O, Arnold M, Nakagawa M, Hamada H, Shelton JM, Kusano H, Harris TM, Childs G, Campbell KP, Richardson JA, Nishino I, Olson EN
Genes & development19(17)2066-77(2005 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In 2 independent murine models of breast tumor metastasis, stable shRNA-based SRPK1 knockdown suppressed metastasis to distant organs, including lung, liver, and spleen, and inhibited focal adhesion reorganization.
Title: Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant.

SRPK1 overexpression is also tumorigenic because excess SRPK1 squelches PHLPP1.
Title: Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.

SRPK1 expression might be an important prognostic indicator for the chemoresponsiveness of nonseminomatous male germ cell tumors.
Title: Resistance to platinum-containing chemotherapy in testicular germ cell tumors is associated with downregulation of the protein kinase SRPK1.

The following Srpk1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Srpk1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10594	NM_016795.4 Latest version!	Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu53371	XM_006523958.4 Latest version!	Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu68787	XM_011246337.3 Latest version!	Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu68787	XM_011246337.2	Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu53371	XM_006523958.3	Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Srpk1 ( NM_016795.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_058075.2 Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), mRNA.

Price & Availability↑

CloneID	OMu10594
Clone ID Related Accession (Same CDS sequence)	NM_016795.4
Accession Version	NM_016795.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1947bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Mus musculus(house mouse)
Product	SRSF protein kinase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK141271.1, AK151152.1 and BE848006.1. On Jan 24, 2017 this sequence version replaced NM_016795.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK151152.1, BC050761.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCGGA AAGTGCTCGC GCTCCAGGCC CGAAAGAAAA GGACCAAGGC CAAGAAGGAC 
AAAGCCCAAA GGAAGCCTGA AACTCAGCAC CGAGGCTCTG CACCCCACTC CGAGAGCGAC 
ATCCCAGAGC AGGAGGAGGA GATTCTAGGG TCTGACGATG ACGAGCAGGA AGACCCCAAT 
GACTACTGTA AAGGAGGTTA TCATCTTGTG AAAATTGGAG ATCTATTTAA CGGGAGATAC 
CATGTGATTC GAAAATTGGG CTGGGGACAC TTTTCCACAG TGTGGTTATC ATGGGATATT 
CAGGGAAAGA AGTTTGTAGC AATGAAAGTA GTTAAAAGTG CTGAGCATTA CACAGAAACA 
GCACTAGATG AAATCCGGCT GCTGAAATCG GTTCGCAACT CAGACCCGAA TGATCCAAAT 
GGAGAAATGG TTGTTCAACT ACTAGATGAC TTTAAAATAT CAGGCGTTAA TGGAACACAT 
ATCTGCATGG TGTTTGAGGT TTTGGGGCAT CATCTACTCA AGTGGATCAT CAAGTCCAAC 
TATCAGGGGC TTCCGCTGCC TTGTGTCAAA AAAATTATTC AGCAAGTGCT ACAGGGCCTG 
GATTACTTAC ACACCAAGTG CCGGATCATC CACACGGACA TCAAACCAGA GAACATCTTG 
TTGTCTGTGA ATGAGCAGTA CATTCGAAGG CTGGCTGCAG AGGCCACAGA GTGGCAGCGC 
TCAGGAGCTC CCCCACCATC GGGGTCTGCA GTCAGCACTG CTCCACAGCC TAAGCCAGCT 
GACAAAATGT CAAAGAATAA GAAGAAGAAA TTGAAGAAGA AGCAGAAGCG CCAGGCAGAA 
TTACTAGAGA AGCGAATGCA GGAAATTGAG GAAATGGAGA AAGAGTCGGG CCCTGGGCAA 
AAAAGACCTA ACAAGCAAGA AGAATCAGAG AGTCCTGTTG ACAGACCCCT GACAGAGAAC 
CCACCTAATA AAATGACCCA AGAGAAACTT GAAGAGTCAA ATTCCATTGG CCAGGACCAG 
ACACTCACGG AGCGTGGTGG AGAGGGTGGT GCGCCAGAGA TTAATTGCAA TGGAGTGATT 
GGAGTCGTTA ATTACCCTGA GAACAGTAAT AATGAGACAC TGAGGCATAA AGAGGATCTG 
CATAATGCTA ATGACTGTGA TGTCCACACT TTGAAGCAGG AACCTAGTTT CCTAAACTCT 
TCAAATGGAG ACAGCAGTCC ATCTCAAGAC ACAGACTCTT GCACACCCAC GGCCTCTGAG 
ACCATGGTGT GCCAATCCTC TGCAGAGCAG TCACTCACCC GACAGGACAT CACCCAGCTG 
GAGGAGAGCA TTCGGGCAGA TACACCTTCT GGGGATGAGC AGGAGCCCAA TGGAGCCCTG 
GACAGCAAAG GAAAATTCTC TGCTGGAAAT TTTCTTATTA ATCCCCTTGA GCCAAAAAAT 
GCAGAGAAGC TCCAAGTGAA GATCGCAGAC CTCGGGAACG CCTGCTGGGT GCACAAGCAT 
TTCACTGAAG ATATCCAGAC ACGGCAGTAT CGGTCTTTGG AAGTCCTGAT AGGATCTGGC 
TACAACACCC CTGCTGACAT CTGGAGCACA GCATGCATGG CCTTTGAACT AGCCACAGGG 
GACTATTTGT TTGAGCCTCA TTCAGGGGAG GATTACACAC GAGATGAAGA CCACATCGCC 
CTGATCATAG AACTTCTGGG GAAGGTGCCT CGCAAGCTCA TTGTGGCAGG AAAATACTCC 
AAGGAATTTT TCACCAAAAA AGGTGACCTG AAGCACATCA CCAAGTTGAA GCCTTGGGGT 
CTTCTGGAGG TTCTGGTGGA GAAATATGAG TGGCCTCAGG AGGAGGCTGC CGGCTTCACA 
GATTTCCTGC TGCCCATGTT GGAGCTTATG CCTGAGAAGA GAGCCACTGC TGCTGAGTGT 
CTCCGGCATC CTTGGCTAAA CTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058075.2
CDS	110..2056
Translation	MERKVLALQARKKRTKAKKDKAQRKPETQHRGSAPHSESDIPEQEEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVDRPLTENPPNKMTQEKLEESNSIGQDQTLTERGGEGGAPEINCNGVIGVVNYPENSNNETLRHKEDLHNANDCDVHTLKQEPSFLNSSNGDSSPSQDTDSCTPTASETMVCQSSAEQSLTRQDITQLEESIRADTPSGDEQEPNGALDSKGKFSAGNFLINPLEPKNAEKLQVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLNS

Target ORF information:

RefSeq Version	NM_016795.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016795.4

ORF Insert Sequence:

ATGGAGCGGA AAGTGCTCGC GCTCCAGGCC CGAAAGAAAA GGACCAAGGC CAAGAAGGAC 
AAAGCCCAAA GGAAGCCTGA AACTCAGCAC CGAGGCTCTG CACCCCACTC CGAGAGCGAC 
ATCCCAGAGC AGGAGGAGGA GATTCTAGGG TCTGACGATG ACGAGCAGGA AGACCCCAAT 
GACTACTGTA AAGGAGGTTA TCATCTTGTG AAAATTGGAG ATCTATTTAA CGGGAGATAC 
CATGTGATTC GAAAATTGGG CTGGGGACAC TTTTCCACAG TGTGGTTATC ATGGGATATT 
CAGGGAAAGA AGTTTGTAGC AATGAAAGTA GTTAAAAGTG CTGAGCATTA CACAGAAACA 
GCACTAGATG AAATCCGGCT GCTGAAATCG GTTCGCAACT CAGACCCGAA TGATCCAAAT 
GGAGAAATGG TTGTTCAACT ACTAGATGAC TTTAAAATAT CAGGCGTTAA TGGAACACAT 
ATCTGCATGG TGTTTGAGGT TTTGGGGCAT CATCTACTCA AGTGGATCAT CAAGTCCAAC 
TATCAGGGGC TTCCGCTGCC TTGTGTCAAA AAAATTATTC AGCAAGTGCT ACAGGGCCTG 
GATTACTTAC ACACCAAGTG CCGGATCATC CACACGGACA TCAAACCAGA GAACATCTTG 
TTGTCTGTGA ATGAGCAGTA CATTCGAAGG CTGGCTGCAG AGGCCACAGA GTGGCAGCGC 
TCAGGAGCTC CCCCACCATC GGGGTCTGCA GTCAGCACTG CTCCACAGCC TAAGCCAGCT 
GACAAAATGT CAAAGAATAA GAAGAAGAAA TTGAAGAAGA AGCAGAAGCG CCAGGCAGAA 
TTACTAGAGA AGCGAATGCA GGAAATTGAG GAAATGGAGA AAGAGTCGGG CCCTGGGCAA 
AAAAGACCTA ACAAGCAAGA AGAATCAGAG AGTCCTGTTG ACAGACCCCT GACAGAGAAC 
CCACCTAATA AAATGACCCA AGAGAAACTT GAAGAGTCAA ATTCCATTGG CCAGGACCAG 
ACACTCACGG AGCGTGGTGG AGAGGGTGGT GCGCCAGAGA TTAATTGCAA TGGAGTGATT 
GGAGTCGTTA ATTACCCTGA GAACAGTAAT AATGAGACAC TGAGGCATAA AGAGGATCTG 
CATAATGCTA ATGACTGTGA TGTCCACACT TTGAAGCAGG AACCTAGTTT CCTAAACTCT 
TCAAATGGAG ACAGCAGTCC ATCTCAAGAC ACAGACTCTT GCACACCCAC GGCCTCTGAG 
ACCATGGTGT GCCAATCCTC TGCAGAGCAG TCACTCACCC GACAGGACAT CACCCAGCTG 
GAGGAGAGCA TTCGGGCAGA TACACCTTCT GGGGATGAGC AGGAGCCCAA TGGAGCCCTG 
GACAGCAAAG GAAAATTCTC TGCTGGAAAT TTTCTTATTA ATCCCCTTGA GCCAAAAAAT 
GCAGAGAAGC TCCAAGTGAA GATCGCAGAC CTCGGGAACG CCTGCTGGGT GCACAAGCAT 
TTCACTGAAG ATATCCAGAC ACGGCAGTAT CGGTCTTTGG AAGTCCTGAT AGGATCTGGC 
TACAACACCC CTGCTGACAT CTGGAGCACA GCATGCATGG CCTTTGAACT AGCCACAGGG 
GACTATTTGT TTGAGCCTCA TTCAGGGGAG GATTACACAC GAGATGAAGA CCACATCGCC 
CTGATCATAG AACTTCTGGG GAAGGTGCCT CGCAAGCTCA TTGTGGCAGG AAAATACTCC 
AAGGAATTTT TCACCAAAAA AGGTGACCTG AAGCACATCA CCAAGTTGAA GCCTTGGGGT 
CTTCTGGAGG TTCTGGTGGA GAAATATGAG TGGCCTCAGG AGGAGGCTGC CGGCTTCACA 
GATTTCCTGC TGCCCATGTT GGAGCTTATG CCTGAGAAGA GAGCCACTGC TGCTGAGTGT 
CTCCGGCATC CTTGGCTAAA CTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Srpk1 ( XM_006523958.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006524021.1 Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu53371
Clone ID Related Accession (Same CDS sequence)	XM_006523958.3 , XM_006523958.4
Accession Version	XM_006523958.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1734bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	SRSF protein kinase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006523958.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCGGA AAGTGCTCGC GCTCCAGGCC CGAAAGAAAA GGACCAAGGC CAAGAAGGAC 
AAAGCCCAAA GGAAGCCTGA AACTCAGCAC CGAGGCTCTG CACCCCACTC CGAGAGCGAC 
ATCCCAGAGC AGGAGGAGGA GATTCTAGGG TCTGACGATG ACGAGCAGGA AGACCCCAAT 
GACTACTGTA AAGGAGGTTA TCATCTTGTG AAAATTGGAG ATCTATTTAA CGGGAGATAC 
CATGTGATTC GAAAATTGGG CTGGGGACAC TTTTCCACAG TGTGGTTATC ATGGGATATT 
CAGGGAAAGA AGTTTGTAGC AATGAAAGTA GTTAAAAGTG CTGAGCATTA CACAGAAACA 
GCACTAGATG AAATCCGGCT GCTGAAATCG GTTCGCAACT CAGACCCGAA TGATCCAAAT 
GGAGAAATGG TTGTTCAACT ACTAGATGAC TTTAAAATAT CAGGCGTTAA TGGAACACAT 
ATCTGCATGG TGTTTGAGGT TTTGGGGCAT CATCTACTCA AGTGGATCAT CAAGTCCAAC 
TATCAGGGGC TTCCGCTGCC TTGTGTCAAA AAAATTATTC AGCAAGTGCT ACAGGGCCTG 
GATTACTTAC ACACCAAGTG CCGGATCATC CACACGGACA TCAAACCAGA GAACATCTTG 
TTGTCTGTGA ATGAGCAGTA CATTCGAAGG CTGGCTGCAG AGGCCACAGA GTGGCAGCGC 
TCAGGAGCTC CCCCACCATC GGGGTCTGCA GTCAGCACTG CTCCACAGCC TAAGCCAGCT 
GACAAAATGT CAAAGAATAA GAAGAAGAAA TTGAAGAAGA AGCAGAAGCG CCAGGCAGAA 
TTACTAGAGA AGCGAATGCA GGAAATTGAG GAAATGGAGA AAGAGTCGGG CCCTGGGCAA 
AAAAGACCTA ACAAGCAAGA AGAATCAGAG AGTCCTGTTG ACAGACCCCT GACAGAGAAC 
CCACCTAATA AAATGACCCA AGAGAAACTT GAAGAGTCAA ATTCCATTGG CCAGGACCAG 
ACACTCACGG AGCGTGGTGG AGAGGGTGGT GCGCCAGAGA TTAATTGCAA TGGAGTGATT 
GGAGTCGTTA ATTACCCTGA GAACAGTAAT AATGAGACAC TGAGGCATAA AGAGGATCTG 
CATAATGCTA ATGACTGTGA TGTCCACACT TTGAAGCAGG AACCTAGTTT CCTAAACTCT 
TCAAATGGAG ACAGCAGTCC ATCTCAAGAC ACAGACTCTT GCACACCCAC GGCCTCTGAG 
ACCATGGTGT GCCAATCCTC TGCAGAGCAG TCACTCACCC GACAGGACAT CACCCAGCTG 
GAGGAGAGCA TTCGGGCAGA TACACCTTCT GGGGATGAGC AGGAGCCCAA TGGAGCCCTG 
GACAGCAAAG GAAAATTCTC TGCTGGAAAT TTTCTTATTA ATCCCCTTGA GCCAAAAAAT 
GCAGAGAAGC TCCAAGTGAA GATCGCAGAC CTCGGGAACG CCTGCTGGGT GCACAAGCAT 
TTCACTGAAG ATATCCAGAC ACGGCAGTAT CGGTCTTTGG AAGTCCTGAT AGGATCTGGC 
TACAACACCC CTGCTGACAT CTGGAGCACA GCATGCATGG CCTTTGAACT AGCCACAGGG 
GACTATTTGT TTGAGCCTCA TTCAGGGGAG GATTACACAC GAGATGAAGG TCAGAAAGCA 
AGTATGCAGT GCCTTACAGA ATGGTATGTG CACCGCTCTG TATGCTGTGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006524021.1
CDS	220..1953
Translation	MERKVLALQARKKRTKAKKDKAQRKPETQHRGSAPHSESDIPEQEEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVDRPLTENPPNKMTQEKLEESNSIGQDQTLTERGGEGGAPEINCNGVIGVVNYPENSNNETLRHKEDLHNANDCDVHTLKQEPSFLNSSNGDSSPSQDTDSCTPTASETMVCQSSAEQSLTRQDITQLEESIRADTPSGDEQEPNGALDSKGKFSAGNFLINPLEPKNAEKLQVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEGQKASMQCLTEWYVHRSVCCV

Target ORF information:

RefSeq Version	XM_006523958.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006523958.3

ORF Insert Sequence:

ATGGAGCGGA AAGTGCTCGC GCTCCAGGCC CGAAAGAAAA GGACCAAGGC CAAGAAGGAC 
AAAGCCCAAA GGAAGCCTGA AACTCAGCAC CGAGGCTCTG CACCCCACTC CGAGAGCGAC 
ATCCCAGAGC AGGAGGAGGA GATTCTAGGG TCTGACGATG ACGAGCAGGA AGACCCCAAT 
GACTACTGTA AAGGAGGTTA TCATCTTGTG AAAATTGGAG ATCTATTTAA CGGGAGATAC 
CATGTGATTC GAAAATTGGG CTGGGGACAC TTTTCCACAG TGTGGTTATC ATGGGATATT 
CAGGGAAAGA AGTTTGTAGC AATGAAAGTA GTTAAAAGTG CTGAGCATTA CACAGAAACA 
GCACTAGATG AAATCCGGCT GCTGAAATCG GTTCGCAACT CAGACCCGAA TGATCCAAAT 
GGAGAAATGG TTGTTCAACT ACTAGATGAC TTTAAAATAT CAGGCGTTAA TGGAACACAT 
ATCTGCATGG TGTTTGAGGT TTTGGGGCAT CATCTACTCA AGTGGATCAT CAAGTCCAAC 
TATCAGGGGC TTCCGCTGCC TTGTGTCAAA AAAATTATTC AGCAAGTGCT ACAGGGCCTG 
GATTACTTAC ACACCAAGTG CCGGATCATC CACACGGACA TCAAACCAGA GAACATCTTG 
TTGTCTGTGA ATGAGCAGTA CATTCGAAGG CTGGCTGCAG AGGCCACAGA GTGGCAGCGC 
TCAGGAGCTC CCCCACCATC GGGGTCTGCA GTCAGCACTG CTCCACAGCC TAAGCCAGCT 
GACAAAATGT CAAAGAATAA GAAGAAGAAA TTGAAGAAGA AGCAGAAGCG CCAGGCAGAA 
TTACTAGAGA AGCGAATGCA GGAAATTGAG GAAATGGAGA AAGAGTCGGG CCCTGGGCAA 
AAAAGACCTA ACAAGCAAGA AGAATCAGAG AGTCCTGTTG ACAGACCCCT GACAGAGAAC 
CCACCTAATA AAATGACCCA AGAGAAACTT GAAGAGTCAA ATTCCATTGG CCAGGACCAG 
ACACTCACGG AGCGTGGTGG AGAGGGTGGT GCGCCAGAGA TTAATTGCAA TGGAGTGATT 
GGAGTCGTTA ATTACCCTGA GAACAGTAAT AATGAGACAC TGAGGCATAA AGAGGATCTG 
CATAATGCTA ATGACTGTGA TGTCCACACT TTGAAGCAGG AACCTAGTTT CCTAAACTCT 
TCAAATGGAG ACAGCAGTCC ATCTCAAGAC ACAGACTCTT GCACACCCAC GGCCTCTGAG 
ACCATGGTGT GCCAATCCTC TGCAGAGCAG TCACTCACCC GACAGGACAT CACCCAGCTG 
GAGGAGAGCA TTCGGGCAGA TACACCTTCT GGGGATGAGC AGGAGCCCAA TGGAGCCCTG 
GACAGCAAAG GAAAATTCTC TGCTGGAAAT TTTCTTATTA ATCCCCTTGA GCCAAAAAAT 
GCAGAGAAGC TCCAAGTGAA GATCGCAGAC CTCGGGAACG CCTGCTGGGT GCACAAGCAT 
TTCACTGAAG ATATCCAGAC ACGGCAGTAT CGGTCTTTGG AAGTCCTGAT AGGATCTGGC 
TACAACACCC CTGCTGACAT CTGGAGCACA GCATGCATGG CCTTTGAACT AGCCACAGGG 
GACTATTTGT TTGAGCCTCA TTCAGGGGAG GATTACACAC GAGATGAAGG TCAGAAAGCA 
AGTATGCAGT GCCTTACAGA ATGGTATGTG CACCGCTCTG TATGCTGTGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Srpk1 ( XM_011246337.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244639.1 Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu68787
Clone ID Related Accession (Same CDS sequence)	XM_011246337.3 , XM_011246337.2
Accession Version	XM_011246337.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1692bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	SRSF protein kinase 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011246337.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCGGA AAGTGCTCGC GCTCCAGGCC CGAAAGAAAA GGACCAAGGC CAAGAAGGAC 
AAAGCCCAAA GGAAGCCTGA AACTCAGCAC CGAGGCTCTG CACCCCACTC CGAGAGCGAC 
ATCCCAGAGC AGGAGGAGGA GATTCTAGGG TCTGACGATG ACGAGCAGGA AGACCCCAAT 
GACTACTGTA AAGGAGGTTA TCATCTTGTG AAAATTGGAG ATCTATTTAA CGGGAGATAC 
CATGTGATTC GAAAATTGGG CTGGGGACAC TTTTCCACAG TGTGGTTATC ATGGGATATT 
CAGGGAAAGA AGTTTGTAGC AATGAAAGTA GTTAAAAGTG CTGAGCATTA CACAGAAACA 
GCACTAGATG AAATCCGGCT GCTGAAATCG GTTCGCAACT CAGACCCGAA TGATCCAAAT 
GGAGAAATGG TTGTTCAACT ACTAGATGAC TTTAAAATAT CAGGCGTTAA TGGAACACAT 
ATCTGCATGG TGTTTGAGGT TTTGGGGCAT CATCTACTCA AGTGGATCAT CAAGTCCAAC 
TATCAGGGGC TTCCGCTGCC TTGTGTCAAA AAAATTATTC AGCAAGTGCT ACAGGGCCTG 
GATTACTTAC ACACCAAGTG CCGGATCATC CACACGGACA TCAAACCAGA GAACATCTTG 
TTGTCTGTGA ATGAGCAGTA CATTCGAAGG CTGGCTGCAG AGGCCACAGA GTGGCAGCGC 
TCAGGAGCTC CCCCACCATC GGGGTCTGCA GTCAGCACTG CTCCACAGCC TAAGCCAGCT 
GACAAAATGT CAAAGAATAA GAAGAAGAAA TTGAAGAAGA AGCAGAAGCG CCAGGCAGAA 
TTACTAGAGA AGCGAATGCA GGAAATTGAG GAAATGGAGA AAGAGTCGGG CCCTGGGCAA 
AAAAGACCTA ACAAGCAAGA AGAATCAGAG AGTCCTGTTG ACAGACCCCT GACAGAGAAC 
CCACCTAATA AAATGACCCA AGAGAAACTT GAAGAGTCAA ATTCCATTGG CCAGGACCAG 
ACACTCACGG AGCGTGGTGG AGAGGGTGGT GCGCCAGAGA TTAATTGCAA TGGAGTGATT 
GGAGTCGTTA ATTACCCTGA GAACAGTAAT AATGAGACAC TGAGGCATAA AGAGGATCTG 
CATAATGCTA ATGACTGTGA TGTCCACACT TTGAAGCAGG AACCTAGTTT CCTAAACTCT 
TCAAATGGAG ACAGCAGTCC ATCTCAAGAC ACAGACTCTT GCACACCCAC GGCCTCTGAG 
ACCATGGTGT GCCAATCCTC TGCAGAGCAG TCACTCACCC GACAGGACAT CACCCAGCTG 
GAGGAGAGCA TTCGGGCAGA TACACCTTCT GGGGATGAGC AGGAGCCCAA TGGAGCCCTG 
GACAGCAAAG GAAAATTCTC TGCTGGAAAT TTTCTTATTA ATCCCCTTGA GCCAAAAAAT 
GCAGAGAAGC TCCAAGTGAA GATCGCAGAC CTCGGGAACG CCTGCTGGGT GCACAAGCAT 
TTCACTGAAG ATATCCAGAC ACGGCAGTAT CGGTCTTTGG AAGTCCTGAT AGGATCTGGC 
TACAACACCC CTGCTGACAT CTGGAGCACA GCATGCATGA CTTGGGATGC CACTGGAAGG 
ATGCTGTCCT CTGCAGTGGG GCCACTCCTC AGATGTCTGG GTCAGTCAGG TGTGAAGCCC 
GGGCACCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244639.1
CDS	228..1919
Translation	MERKVLALQARKKRTKAKKDKAQRKPETQHRGSAPHSESDIPEQEEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVDRPLTENPPNKMTQEKLEESNSIGQDQTLTERGGEGGAPEINCNGVIGVVNYPENSNNETLRHKEDLHNANDCDVHTLKQEPSFLNSSNGDSSPSQDTDSCTPTASETMVCQSSAEQSLTRQDITQLEESIRADTPSGDEQEPNGALDSKGKFSAGNFLINPLEPKNAEKLQVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMTWDATGRMLSSAVGPLLRCLGQSGVKPGHL

Target ORF information:

RefSeq Version	XM_011246337.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246337.2

ORF Insert Sequence:

ATGGAGCGGA AAGTGCTCGC GCTCCAGGCC CGAAAGAAAA GGACCAAGGC CAAGAAGGAC 
AAAGCCCAAA GGAAGCCTGA AACTCAGCAC CGAGGCTCTG CACCCCACTC CGAGAGCGAC 
ATCCCAGAGC AGGAGGAGGA GATTCTAGGG TCTGACGATG ACGAGCAGGA AGACCCCAAT 
GACTACTGTA AAGGAGGTTA TCATCTTGTG AAAATTGGAG ATCTATTTAA CGGGAGATAC 
CATGTGATTC GAAAATTGGG CTGGGGACAC TTTTCCACAG TGTGGTTATC ATGGGATATT 
CAGGGAAAGA AGTTTGTAGC AATGAAAGTA GTTAAAAGTG CTGAGCATTA CACAGAAACA 
GCACTAGATG AAATCCGGCT GCTGAAATCG GTTCGCAACT CAGACCCGAA TGATCCAAAT 
GGAGAAATGG TTGTTCAACT ACTAGATGAC TTTAAAATAT CAGGCGTTAA TGGAACACAT 
ATCTGCATGG TGTTTGAGGT TTTGGGGCAT CATCTACTCA AGTGGATCAT CAAGTCCAAC 
TATCAGGGGC TTCCGCTGCC TTGTGTCAAA AAAATTATTC AGCAAGTGCT ACAGGGCCTG 
GATTACTTAC ACACCAAGTG CCGGATCATC CACACGGACA TCAAACCAGA GAACATCTTG 
TTGTCTGTGA ATGAGCAGTA CATTCGAAGG CTGGCTGCAG AGGCCACAGA GTGGCAGCGC 
TCAGGAGCTC CCCCACCATC GGGGTCTGCA GTCAGCACTG CTCCACAGCC TAAGCCAGCT 
GACAAAATGT CAAAGAATAA GAAGAAGAAA TTGAAGAAGA AGCAGAAGCG CCAGGCAGAA 
TTACTAGAGA AGCGAATGCA GGAAATTGAG GAAATGGAGA AAGAGTCGGG CCCTGGGCAA 
AAAAGACCTA ACAAGCAAGA AGAATCAGAG AGTCCTGTTG ACAGACCCCT GACAGAGAAC 
CCACCTAATA AAATGACCCA AGAGAAACTT GAAGAGTCAA ATTCCATTGG CCAGGACCAG 
ACACTCACGG AGCGTGGTGG AGAGGGTGGT GCGCCAGAGA TTAATTGCAA TGGAGTGATT 
GGAGTCGTTA ATTACCCTGA GAACAGTAAT AATGAGACAC TGAGGCATAA AGAGGATCTG 
CATAATGCTA ATGACTGTGA TGTCCACACT TTGAAGCAGG AACCTAGTTT CCTAAACTCT 
TCAAATGGAG ACAGCAGTCC ATCTCAAGAC ACAGACTCTT GCACACCCAC GGCCTCTGAG 
ACCATGGTGT GCCAATCCTC TGCAGAGCAG TCACTCACCC GACAGGACAT CACCCAGCTG 
GAGGAGAGCA TTCGGGCAGA TACACCTTCT GGGGATGAGC AGGAGCCCAA TGGAGCCCTG 
GACAGCAAAG GAAAATTCTC TGCTGGAAAT TTTCTTATTA ATCCCCTTGA GCCAAAAAAT 
GCAGAGAAGC TCCAAGTGAA GATCGCAGAC CTCGGGAACG CCTGCTGGGT GCACAAGCAT 
TTCACTGAAG ATATCCAGAC ACGGCAGTAT CGGTCTTTGG AAGTCCTGAT AGGATCTGGC 
TACAACACCC CTGCTGACAT CTGGAGCACA GCATGCATGA CTTGGGATGC CACTGGAAGG 
ATGCTGTCCT CTGCAGTGGG GCCACTCCTC AGATGTCTGG GTCAGTCAGG TGTGAAGCCC 
GGGCACCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Srpk1 ( XM_006523958.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006524021.1 Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu53371
Clone ID Related Accession (Same CDS sequence)	XM_006523958.3 , XM_006523958.4
Accession Version	XM_006523958.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1734bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	SRSF protein kinase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006523958.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCGGA AAGTGCTCGC GCTCCAGGCC CGAAAGAAAA GGACCAAGGC CAAGAAGGAC 
AAAGCCCAAA GGAAGCCTGA AACTCAGCAC CGAGGCTCTG CACCCCACTC CGAGAGCGAC 
ATCCCAGAGC AGGAGGAGGA GATTCTAGGG TCTGACGATG ACGAGCAGGA AGACCCCAAT 
GACTACTGTA AAGGAGGTTA TCATCTTGTG AAAATTGGAG ATCTATTTAA CGGGAGATAC 
CATGTGATTC GAAAATTGGG CTGGGGACAC TTTTCCACAG TGTGGTTATC ATGGGATATT 
CAGGGAAAGA AGTTTGTAGC AATGAAAGTA GTTAAAAGTG CTGAGCATTA CACAGAAACA 
GCACTAGATG AAATCCGGCT GCTGAAATCG GTTCGCAACT CAGACCCGAA TGATCCAAAT 
GGAGAAATGG TTGTTCAACT ACTAGATGAC TTTAAAATAT CAGGCGTTAA TGGAACACAT 
ATCTGCATGG TGTTTGAGGT TTTGGGGCAT CATCTACTCA AGTGGATCAT CAAGTCCAAC 
TATCAGGGGC TTCCGCTGCC TTGTGTCAAA AAAATTATTC AGCAAGTGCT ACAGGGCCTG 
GATTACTTAC ACACCAAGTG CCGGATCATC CACACGGACA TCAAACCAGA GAACATCTTG 
TTGTCTGTGA ATGAGCAGTA CATTCGAAGG CTGGCTGCAG AGGCCACAGA GTGGCAGCGC 
TCAGGAGCTC CCCCACCATC GGGGTCTGCA GTCAGCACTG CTCCACAGCC TAAGCCAGCT 
GACAAAATGT CAAAGAATAA GAAGAAGAAA TTGAAGAAGA AGCAGAAGCG CCAGGCAGAA 
TTACTAGAGA AGCGAATGCA GGAAATTGAG GAAATGGAGA AAGAGTCGGG CCCTGGGCAA 
AAAAGACCTA ACAAGCAAGA AGAATCAGAG AGTCCTGTTG ACAGACCCCT GACAGAGAAC 
CCACCTAATA AAATGACCCA AGAGAAACTT GAAGAGTCAA ATTCCATTGG CCAGGACCAG 
ACACTCACGG AGCGTGGTGG AGAGGGTGGT GCGCCAGAGA TTAATTGCAA TGGAGTGATT 
GGAGTCGTTA ATTACCCTGA GAACAGTAAT AATGAGACAC TGAGGCATAA AGAGGATCTG 
CATAATGCTA ATGACTGTGA TGTCCACACT TTGAAGCAGG AACCTAGTTT CCTAAACTCT 
TCAAATGGAG ACAGCAGTCC ATCTCAAGAC ACAGACTCTT GCACACCCAC GGCCTCTGAG 
ACCATGGTGT GCCAATCCTC TGCAGAGCAG TCACTCACCC GACAGGACAT CACCCAGCTG 
GAGGAGAGCA TTCGGGCAGA TACACCTTCT GGGGATGAGC AGGAGCCCAA TGGAGCCCTG 
GACAGCAAAG GAAAATTCTC TGCTGGAAAT TTTCTTATTA ATCCCCTTGA GCCAAAAAAT 
GCAGAGAAGC TCCAAGTGAA GATCGCAGAC CTCGGGAACG CCTGCTGGGT GCACAAGCAT 
TTCACTGAAG ATATCCAGAC ACGGCAGTAT CGGTCTTTGG AAGTCCTGAT AGGATCTGGC 
TACAACACCC CTGCTGACAT CTGGAGCACA GCATGCATGG CCTTTGAACT AGCCACAGGG 
GACTATTTGT TTGAGCCTCA TTCAGGGGAG GATTACACAC GAGATGAAGG TCAGAAAGCA 
AGTATGCAGT GCCTTACAGA ATGGTATGTG CACCGCTCTG TATGCTGTGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006524021.1
CDS	116..1849
Translation	MERKVLALQARKKRTKAKKDKAQRKPETQHRGSAPHSESDIPEQEEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVDRPLTENPPNKMTQEKLEESNSIGQDQTLTERGGEGGAPEINCNGVIGVVNYPENSNNETLRHKEDLHNANDCDVHTLKQEPSFLNSSNGDSSPSQDTDSCTPTASETMVCQSSAEQSLTRQDITQLEESIRADTPSGDEQEPNGALDSKGKFSAGNFLINPLEPKNAEKLQVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEGQKASMQCLTEWYVHRSVCCV

Target ORF information:

RefSeq Version	XM_006523958.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006523958.4

ORF Insert Sequence:

ATGGAGCGGA AAGTGCTCGC GCTCCAGGCC CGAAAGAAAA GGACCAAGGC CAAGAAGGAC 
AAAGCCCAAA GGAAGCCTGA AACTCAGCAC CGAGGCTCTG CACCCCACTC CGAGAGCGAC 
ATCCCAGAGC AGGAGGAGGA GATTCTAGGG TCTGACGATG ACGAGCAGGA AGACCCCAAT 
GACTACTGTA AAGGAGGTTA TCATCTTGTG AAAATTGGAG ATCTATTTAA CGGGAGATAC 
CATGTGATTC GAAAATTGGG CTGGGGACAC TTTTCCACAG TGTGGTTATC ATGGGATATT 
CAGGGAAAGA AGTTTGTAGC AATGAAAGTA GTTAAAAGTG CTGAGCATTA CACAGAAACA 
GCACTAGATG AAATCCGGCT GCTGAAATCG GTTCGCAACT CAGACCCGAA TGATCCAAAT 
GGAGAAATGG TTGTTCAACT ACTAGATGAC TTTAAAATAT CAGGCGTTAA TGGAACACAT 
ATCTGCATGG TGTTTGAGGT TTTGGGGCAT CATCTACTCA AGTGGATCAT CAAGTCCAAC 
TATCAGGGGC TTCCGCTGCC TTGTGTCAAA AAAATTATTC AGCAAGTGCT ACAGGGCCTG 
GATTACTTAC ACACCAAGTG CCGGATCATC CACACGGACA TCAAACCAGA GAACATCTTG 
TTGTCTGTGA ATGAGCAGTA CATTCGAAGG CTGGCTGCAG AGGCCACAGA GTGGCAGCGC 
TCAGGAGCTC CCCCACCATC GGGGTCTGCA GTCAGCACTG CTCCACAGCC TAAGCCAGCT 
GACAAAATGT CAAAGAATAA GAAGAAGAAA TTGAAGAAGA AGCAGAAGCG CCAGGCAGAA 
TTACTAGAGA AGCGAATGCA GGAAATTGAG GAAATGGAGA AAGAGTCGGG CCCTGGGCAA 
AAAAGACCTA ACAAGCAAGA AGAATCAGAG AGTCCTGTTG ACAGACCCCT GACAGAGAAC 
CCACCTAATA AAATGACCCA AGAGAAACTT GAAGAGTCAA ATTCCATTGG CCAGGACCAG 
ACACTCACGG AGCGTGGTGG AGAGGGTGGT GCGCCAGAGA TTAATTGCAA TGGAGTGATT 
GGAGTCGTTA ATTACCCTGA GAACAGTAAT AATGAGACAC TGAGGCATAA AGAGGATCTG 
CATAATGCTA ATGACTGTGA TGTCCACACT TTGAAGCAGG AACCTAGTTT CCTAAACTCT 
TCAAATGGAG ACAGCAGTCC ATCTCAAGAC ACAGACTCTT GCACACCCAC GGCCTCTGAG 
ACCATGGTGT GCCAATCCTC TGCAGAGCAG TCACTCACCC GACAGGACAT CACCCAGCTG 
GAGGAGAGCA TTCGGGCAGA TACACCTTCT GGGGATGAGC AGGAGCCCAA TGGAGCCCTG 
GACAGCAAAG GAAAATTCTC TGCTGGAAAT TTTCTTATTA ATCCCCTTGA GCCAAAAAAT 
GCAGAGAAGC TCCAAGTGAA GATCGCAGAC CTCGGGAACG CCTGCTGGGT GCACAAGCAT 
TTCACTGAAG ATATCCAGAC ACGGCAGTAT CGGTCTTTGG AAGTCCTGAT AGGATCTGGC 
TACAACACCC CTGCTGACAT CTGGAGCACA GCATGCATGG CCTTTGAACT AGCCACAGGG 
GACTATTTGT TTGAGCCTCA TTCAGGGGAG GATTACACAC GAGATGAAGG TCAGAAAGCA 
AGTATGCAGT GCCTTACAGA ATGGTATGTG CACCGCTCTG TATGCTGTGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Srpk1 ( XM_011246337.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244639.1 Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu68787
Clone ID Related Accession (Same CDS sequence)	XM_011246337.3 , XM_011246337.2
Accession Version	XM_011246337.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1692bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	SRSF protein kinase 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011246337.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCGGA AAGTGCTCGC GCTCCAGGCC CGAAAGAAAA GGACCAAGGC CAAGAAGGAC 
AAAGCCCAAA GGAAGCCTGA AACTCAGCAC CGAGGCTCTG CACCCCACTC CGAGAGCGAC 
ATCCCAGAGC AGGAGGAGGA GATTCTAGGG TCTGACGATG ACGAGCAGGA AGACCCCAAT 
GACTACTGTA AAGGAGGTTA TCATCTTGTG AAAATTGGAG ATCTATTTAA CGGGAGATAC 
CATGTGATTC GAAAATTGGG CTGGGGACAC TTTTCCACAG TGTGGTTATC ATGGGATATT 
CAGGGAAAGA AGTTTGTAGC AATGAAAGTA GTTAAAAGTG CTGAGCATTA CACAGAAACA 
GCACTAGATG AAATCCGGCT GCTGAAATCG GTTCGCAACT CAGACCCGAA TGATCCAAAT 
GGAGAAATGG TTGTTCAACT ACTAGATGAC TTTAAAATAT CAGGCGTTAA TGGAACACAT 
ATCTGCATGG TGTTTGAGGT TTTGGGGCAT CATCTACTCA AGTGGATCAT CAAGTCCAAC 
TATCAGGGGC TTCCGCTGCC TTGTGTCAAA AAAATTATTC AGCAAGTGCT ACAGGGCCTG 
GATTACTTAC ACACCAAGTG CCGGATCATC CACACGGACA TCAAACCAGA GAACATCTTG 
TTGTCTGTGA ATGAGCAGTA CATTCGAAGG CTGGCTGCAG AGGCCACAGA GTGGCAGCGC 
TCAGGAGCTC CCCCACCATC GGGGTCTGCA GTCAGCACTG CTCCACAGCC TAAGCCAGCT 
GACAAAATGT CAAAGAATAA GAAGAAGAAA TTGAAGAAGA AGCAGAAGCG CCAGGCAGAA 
TTACTAGAGA AGCGAATGCA GGAAATTGAG GAAATGGAGA AAGAGTCGGG CCCTGGGCAA 
AAAAGACCTA ACAAGCAAGA AGAATCAGAG AGTCCTGTTG ACAGACCCCT GACAGAGAAC 
CCACCTAATA AAATGACCCA AGAGAAACTT GAAGAGTCAA ATTCCATTGG CCAGGACCAG 
ACACTCACGG AGCGTGGTGG AGAGGGTGGT GCGCCAGAGA TTAATTGCAA TGGAGTGATT 
GGAGTCGTTA ATTACCCTGA GAACAGTAAT AATGAGACAC TGAGGCATAA AGAGGATCTG 
CATAATGCTA ATGACTGTGA TGTCCACACT TTGAAGCAGG AACCTAGTTT CCTAAACTCT 
TCAAATGGAG ACAGCAGTCC ATCTCAAGAC ACAGACTCTT GCACACCCAC GGCCTCTGAG 
ACCATGGTGT GCCAATCCTC TGCAGAGCAG TCACTCACCC GACAGGACAT CACCCAGCTG 
GAGGAGAGCA TTCGGGCAGA TACACCTTCT GGGGATGAGC AGGAGCCCAA TGGAGCCCTG 
GACAGCAAAG GAAAATTCTC TGCTGGAAAT TTTCTTATTA ATCCCCTTGA GCCAAAAAAT 
GCAGAGAAGC TCCAAGTGAA GATCGCAGAC CTCGGGAACG CCTGCTGGGT GCACAAGCAT 
TTCACTGAAG ATATCCAGAC ACGGCAGTAT CGGTCTTTGG AAGTCCTGAT AGGATCTGGC 
TACAACACCC CTGCTGACAT CTGGAGCACA GCATGCATGA CTTGGGATGC CACTGGAAGG 
ATGCTGTCCT CTGCAGTGGG GCCACTCCTC AGATGTCTGG GTCAGTCAGG TGTGAAGCCC 
GGGCACCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244639.1
CDS	116..1807
Translation	MERKVLALQARKKRTKAKKDKAQRKPETQHRGSAPHSESDIPEQEEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVDRPLTENPPNKMTQEKLEESNSIGQDQTLTERGGEGGAPEINCNGVIGVVNYPENSNNETLRHKEDLHNANDCDVHTLKQEPSFLNSSNGDSSPSQDTDSCTPTASETMVCQSSAEQSLTRQDITQLEESIRADTPSGDEQEPNGALDSKGKFSAGNFLINPLEPKNAEKLQVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMTWDATGRMLSSAVGPLLRCLGQSGVKPGHL

Target ORF information:

RefSeq Version	XM_011246337.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus serine/arginine-rich protein specific kinase 1 (Srpk1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246337.3

ORF Insert Sequence:

ATGGAGCGGA AAGTGCTCGC GCTCCAGGCC CGAAAGAAAA GGACCAAGGC CAAGAAGGAC 
AAAGCCCAAA GGAAGCCTGA AACTCAGCAC CGAGGCTCTG CACCCCACTC CGAGAGCGAC 
ATCCCAGAGC AGGAGGAGGA GATTCTAGGG TCTGACGATG ACGAGCAGGA AGACCCCAAT 
GACTACTGTA AAGGAGGTTA TCATCTTGTG AAAATTGGAG ATCTATTTAA CGGGAGATAC 
CATGTGATTC GAAAATTGGG CTGGGGACAC TTTTCCACAG TGTGGTTATC ATGGGATATT 
CAGGGAAAGA AGTTTGTAGC AATGAAAGTA GTTAAAAGTG CTGAGCATTA CACAGAAACA 
GCACTAGATG AAATCCGGCT GCTGAAATCG GTTCGCAACT CAGACCCGAA TGATCCAAAT 
GGAGAAATGG TTGTTCAACT ACTAGATGAC TTTAAAATAT CAGGCGTTAA TGGAACACAT 
ATCTGCATGG TGTTTGAGGT TTTGGGGCAT CATCTACTCA AGTGGATCAT CAAGTCCAAC 
TATCAGGGGC TTCCGCTGCC TTGTGTCAAA AAAATTATTC AGCAAGTGCT ACAGGGCCTG 
GATTACTTAC ACACCAAGTG CCGGATCATC CACACGGACA TCAAACCAGA GAACATCTTG 
TTGTCTGTGA ATGAGCAGTA CATTCGAAGG CTGGCTGCAG AGGCCACAGA GTGGCAGCGC 
TCAGGAGCTC CCCCACCATC GGGGTCTGCA GTCAGCACTG CTCCACAGCC TAAGCCAGCT 
GACAAAATGT CAAAGAATAA GAAGAAGAAA TTGAAGAAGA AGCAGAAGCG CCAGGCAGAA 
TTACTAGAGA AGCGAATGCA GGAAATTGAG GAAATGGAGA AAGAGTCGGG CCCTGGGCAA 
AAAAGACCTA ACAAGCAAGA AGAATCAGAG AGTCCTGTTG ACAGACCCCT GACAGAGAAC 
CCACCTAATA AAATGACCCA AGAGAAACTT GAAGAGTCAA ATTCCATTGG CCAGGACCAG 
ACACTCACGG AGCGTGGTGG AGAGGGTGGT GCGCCAGAGA TTAATTGCAA TGGAGTGATT 
GGAGTCGTTA ATTACCCTGA GAACAGTAAT AATGAGACAC TGAGGCATAA AGAGGATCTG 
CATAATGCTA ATGACTGTGA TGTCCACACT TTGAAGCAGG AACCTAGTTT CCTAAACTCT 
TCAAATGGAG ACAGCAGTCC ATCTCAAGAC ACAGACTCTT GCACACCCAC GGCCTCTGAG 
ACCATGGTGT GCCAATCCTC TGCAGAGCAG TCACTCACCC GACAGGACAT CACCCAGCTG 
GAGGAGAGCA TTCGGGCAGA TACACCTTCT GGGGATGAGC AGGAGCCCAA TGGAGCCCTG 
GACAGCAAAG GAAAATTCTC TGCTGGAAAT TTTCTTATTA ATCCCCTTGA GCCAAAAAAT 
GCAGAGAAGC TCCAAGTGAA GATCGCAGAC CTCGGGAACG CCTGCTGGGT GCACAAGCAT 
TTCACTGAAG ATATCCAGAC ACGGCAGTAT CGGTCTTTGG AAGTCCTGAT AGGATCTGGC 
TACAACACCC CTGCTGACAT CTGGAGCACA GCATGCATGA CTTGGGATGC CACTGGAAGG 
ATGCTGTCCT CTGCAGTGGG GCCACTCCTC AGATGTCTGG GTCAGTCAGG TGTGAAGCCC 
GGGCACCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant.
The Journal of clinical investigation125(4)1648-64(2015 Apr)
van Roosmalen W,Le D?v?dec SE,Golani O,Smid M,Pulyakhina I,Timmermans AM,Look MP,Zi D,Pont C,de Graauw M,Naffar-Abu-Amara S,Kirsanova C,Rustici G,Hoen PA,Martens JW,Foekens JA,Geiger B,van de Water B

Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.
Molecular cell54(3)378-91(2014 May)
Wang P,Zhou Z,Hu A,Ponte de Albuquerque C,Zhou Y,Hong L,Sierecki E,Ajiro M,Kruhlak M,Harris C,Guan KL,Zheng ZM,Newton AC,Sun P,Zhou H,Fu XD

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
PLoS genetics5(6)e1000511(2009 Jun)
Sansom SN,Griffiths DS,Faedo A,Kleinjan DJ,Ruan Y,Smith J,van Heyningen V,Rubenstein JL,Livesey FJ

Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2.
Genes & development19(17)2066-77(2005 Sep)
Nakagawa O,Arnold M,Nakagawa M,Hamada H,Shelton JM,Kusano H,Harris TM,Childs G,Campbell KP,Richardson JA,Nishino I,Olson EN

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Srpk1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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