Fgr cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fgr
Entrez Gene ID	14191
Full Name	FGR proto-oncogene, Src family tyrosine kinase
General protein information	Preferred Names FGR proto-oncogene, Src family tyrosine kinase Names tyrosine-protein kinase Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog p55-Fgr proto-oncogene c-Fgr proto-oncogene tyrosine-protein kinase Fgr
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4 D2.3\|4 66.11 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006538544.3	XP_006538607.1	tyrosine-protein kinase Fgr isoform X1
XM_006538545.4	XP_006538608.1	tyrosine-protein kinase Fgr isoform X1
XM_006538545.3	XP_006538608.1	tyrosine-protein kinase Fgr isoform X1
XM_006538544.4	XP_006538607.1	tyrosine-protein kinase Fgr isoform X1
NM_010208.4	NP_034338.3	tyrosine-protein kinase Fgr

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FGR	XP_003307959.1
	FGR	XP_001111732.1
Mus musculus (house mouse)	Fgr	NP_034338.3
Homo sapiens (human)	FGR	NP_005239.1
Bos taurus (cattle)	FGR	NP_001092461.1
Rattus norvegicus (Norway rat)	Fgr	NP_077059.2
Gallus gallus (chicken)	YRK	NP_001103257.1
Danio rerio (zebrafish)	yrk	NP_997946.1
Canis lupus familiaris (dog)	FGR	XP_005617769.1
Xenopus tropicalis (tropical clawed frog)	LOC100493811	XP_002934688.1

Gene Ontology
Bibliography

Related articles in PubMed

The Syk Tyrosine Kinase Is Required for Skin Inflammation in an In?Vivo Mouse Model of?Epidermolysis Bullosa Acquisita.
N?meth T, Virtic O, Sitaru C, M?csai A
The Journal of investigative dermatology137(10)2131-2139(2017 Oct)

The Src kinases Hck, Fgr and Lyn activate Arg to facilitate IgG-mediated phagocytosis and Leishmania infection.
Wetzel DM, Rhodes EL, Li S, McMahon-Pratt D, Koleske AJ
Journal of cell science129(16)3130-43(2016 08)

Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo.
N?meth T, Futosi K, Sitaru C, Ruland J, M?csai A
Nature communications711004(2016 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the Hck, Fgr and Lyn kinases are also necessary for amastigote uptake by macrophages. Src-mediated Arg activation is required for efficient uptake.
Title: The Src kinases Hck, Fgr and Lyn activate Arg to facilitate IgG-mediated phagocytosis and Leishmania infection.

Data indicate that Src-Family Kinases Hck and Fgr regulate cytokine secretion by macrophages.
Title: The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines.

Fgr is not only are progressively overexpressed in atherosclerosis, but it also controls critical molecular processes in monocyte influx, blood monocyte subset balance, macrophage accumulation, and the maintenance of atherosclerotic lesion stability.
Title: Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility.

The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.
Title: The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.

Ablation of Fgr abolishes the capacity of mitochondria to adjust metabolism upon nutrient restriction, hypoxia/reoxygenation, and T cell activation, demonstrating the physiological relevance of this adaptive response.
Title: ROS-triggered phosphorylation of complex II by Fgr kinase regulates cellular adaptation to fuel use.

The following Fgr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fgr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu22496	NM_010208.4 Latest version!	Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$300.30 $429.00
OMu22496	XM_006538544.4 Latest version!	Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu22496	XM_006538545.4 Latest version!	Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu22496	XM_006538545.3	Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$300.30 $429.00
OMu22496	XM_006538544.3	Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$300.30 $429.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fgr ( NM_010208.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034338.3 Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), mRNA.

Price & Availability↑

CloneID	OMu22496
Clone ID Related Accession (Same CDS sequence)	XM_006538544.3 , XM_006538545.4 , XM_006538545.3 , XM_006538544.4 , NM_010208.4
Accession Version	NM_010208.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	tyrosine-protein kinase Fgr
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY204076.1, AK155902.1, AK038141.1 and AI661913.1. On Apr 1, 2008 this sequence version replaced NM_010208.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK157640.1, AK038141.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END##

ATGGGCTGTG TGTTCTGCAA GAAGTTGGAG CCTGCATCCA AGGAGGATGT GGGCCTGGAA 
GGGGACTTCC GGAGCCAAAC GGCTGAAGAA CGCTATTTCC CTGACCCCAC TCAAGGCCGG 
ACTTCGTCCG TCTTTCCTCA GCCCACCAGC CCTGCTTTCC TCAACACTGG CAACATGAGA 
AGCATCTCAG GGACCGGAGT GACCATATTC GTCGCCCTGT ACGACTATGA GGCCAGGACA 
GGGGATGACC TCACCTTCAC CAAAGGCGAG AAGTTCCACA TCCTGAACAA TACGGAGTAT 
GACTGGTGGG AGGCTCGCTC CCTGAGCTCC GGACACAGAG GCTATGTTCC CAGCAACTAT 
GTTGCTCCTG TGGATTCCAT CCAGGCTGAA GAGTGGTACT TCGGAAAGAT CAGTAGAAAG 
GATGCAGAGA GGCAGCTTCT GTCCTCTGGT AACCCCCAGG GGGCCTTTCT CATTCGGGAA 
AGCGAGACCA CCAAAGGGGC CTACTCCCTG TCCATCCGTG ACTGGGACCA GAACAGAGGC 
GATCACATAA AGCATTATAA GATCCGAAAG CTGGACACGG GCGGCTACTA CATCACCACA 
CGGGCCCAGT TTGACTCCAT ACAGGACCTA GTGCGGCACT ACATGGAAGT GAATGATGGT 
CTGTGCTACT TGCTTACGGC GCCTTGTACC ACCACTAAGC CCCAGACTCT AGGCCTGGCC 
AAGGATGCCT GGGAGATCGA CCGGAACTCC ATAGCACTGG AACGCAGGCT GGGCACCGGC 
TGCTTTGGAG ATGTGTGGCT GGGCACATGG AACTGCAGCA CAAAGGTGGC AGTGAAGACG 
CTGAAGCCGG GCACCATGTC CCCGAAGGCA TTCCTGGAGG AGGCACAGAT CATGAAGCTG 
CTGAGGCACG ACAAGCTGGT GCAGCTGTAT GCGGTGGTGT CGGAGGAACC CATTTATATT 
GTGACAGAGT TCATGTGCTA TGGTAGCTTG CTGGATTTCC TAAAGGATCG AGAAGGTCAG 
AACTTGATGC TGCCCCATCT AGTGGACATG GCTGCCCAGG TAGCCGAGGG CATGGCCTAC 
ATGGAACGCA TGAACTATAT CCACCGAGAC TTGAGGGCAG CCAACATCCT GGTGGGGGAA 
TACCTAATAT GCAAGATCGC TGACTTCGGG CTGGCACGCC TCATAGAGGA CAATGAGTAT 
AACCCCCAAC AAGGAACCAA GTTCCCCATC AAGTGGACAG CCCCAGAGGC CGCCCTCTTT 
GGCAGATTCA CTGTCAAATC AGACGTGTGG TCCTTTGGGA TTCTGCTCAC TGAACTGATC 
ACCAAGGGCA GAGTTCCCTA CCCAGGTATG AACAACCGGG AAGTGTTGGA ACAGGTGGAG 
CATGGCTACC ACATGCCGTG CCCTCCAGGA TGTCCTGCAT CCCTGTATGA GGTCATGGAG 
CAGGCGTGGC GCCTGGATCC AGAGGAGAGG CCCACCTTTG AGTACCTGCA GTCTTTCCTG 
GAAGACTATT TCACCTCCAC AGAACCACAG TACCAGCCTG GAGACCAGAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034338.3
CDS	250..1803
Translation	MGCVFCKKLEPASKEDVGLEGDFRSQTAEERYFPDPTQGRTSSVFPQPTSPAFLNTGNMRSISGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGHRGYVPSNYVAPVDSIQAEEWYFGKISRKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDTGGYYITTRAQFDSIQDLVRHYMEVNDGLCYLLTAPCTTTKPQTLGLAKDAWEIDRNSIALERRLGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQT

Target ORF information:

RefSeq Version	NM_010208.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010208.4

ORF Insert Sequence:

ATGGGCTGTG TGTTCTGCAA GAAGTTGGAG CCTGCATCCA AGGAGGATGT GGGCCTGGAA 
GGGGACTTCC GGAGCCAAAC GGCTGAAGAA CGCTATTTCC CTGACCCCAC TCAAGGCCGG 
ACTTCGTCCG TCTTTCCTCA GCCCACCAGC CCTGCTTTCC TCAACACTGG CAACATGAGA 
AGCATCTCAG GGACCGGAGT GACCATATTC GTCGCCCTGT ACGACTATGA GGCCAGGACA 
GGGGATGACC TCACCTTCAC CAAAGGCGAG AAGTTCCACA TCCTGAACAA TACGGAGTAT 
GACTGGTGGG AGGCTCGCTC CCTGAGCTCC GGACACAGAG GCTATGTTCC CAGCAACTAT 
GTTGCTCCTG TGGATTCCAT CCAGGCTGAA GAGTGGTACT TCGGAAAGAT CAGTAGAAAG 
GATGCAGAGA GGCAGCTTCT GTCCTCTGGT AACCCCCAGG GGGCCTTTCT CATTCGGGAA 
AGCGAGACCA CCAAAGGGGC CTACTCCCTG TCCATCCGTG ACTGGGACCA GAACAGAGGC 
GATCACATAA AGCATTATAA GATCCGAAAG CTGGACACGG GCGGCTACTA CATCACCACA 
CGGGCCCAGT TTGACTCCAT ACAGGACCTA GTGCGGCACT ACATGGAAGT GAATGATGGT 
CTGTGCTACT TGCTTACGGC GCCTTGTACC ACCACTAAGC CCCAGACTCT AGGCCTGGCC 
AAGGATGCCT GGGAGATCGA CCGGAACTCC ATAGCACTGG AACGCAGGCT GGGCACCGGC 
TGCTTTGGAG ATGTGTGGCT GGGCACATGG AACTGCAGCA CAAAGGTGGC AGTGAAGACG 
CTGAAGCCGG GCACCATGTC CCCGAAGGCA TTCCTGGAGG AGGCACAGAT CATGAAGCTG 
CTGAGGCACG ACAAGCTGGT GCAGCTGTAT GCGGTGGTGT CGGAGGAACC CATTTATATT 
GTGACAGAGT TCATGTGCTA TGGTAGCTTG CTGGATTTCC TAAAGGATCG AGAAGGTCAG 
AACTTGATGC TGCCCCATCT AGTGGACATG GCTGCCCAGG TAGCCGAGGG CATGGCCTAC 
ATGGAACGCA TGAACTATAT CCACCGAGAC TTGAGGGCAG CCAACATCCT GGTGGGGGAA 
TACCTAATAT GCAAGATCGC TGACTTCGGG CTGGCACGCC TCATAGAGGA CAATGAGTAT 
AACCCCCAAC AAGGAACCAA GTTCCCCATC AAGTGGACAG CCCCAGAGGC CGCCCTCTTT 
GGCAGATTCA CTGTCAAATC AGACGTGTGG TCCTTTGGGA TTCTGCTCAC TGAACTGATC 
ACCAAGGGCA GAGTTCCCTA CCCAGGTATG AACAACCGGG AAGTGTTGGA ACAGGTGGAG 
CATGGCTACC ACATGCCGTG CCCTCCAGGA TGTCCTGCAT CCCTGTATGA GGTCATGGAG 
CAGGCGTGGC GCCTGGATCC AGAGGAGAGG CCCACCTTTG AGTACCTGCA GTCTTTCCTG 
GAAGACTATT TCACCTCCAC AGAACCACAG TACCAGCCTG GAGACCAGAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgr ( XM_006538544.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006538607.1 Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu22496
Clone ID Related Accession (Same CDS sequence)	XM_006538544.3 , XM_006538545.4 , XM_006538545.3 , XM_006538544.4 , NM_010208.4
Accession Version	XM_006538544.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	tyrosine-protein kinase Fgr isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006538544.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCTGTG TGTTCTGCAA GAAGTTGGAG CCTGCATCCA AGGAGGATGT GGGCCTGGAA 
GGGGACTTCC GGAGCCAAAC GGCTGAAGAA CGCTATTTCC CTGACCCCAC TCAAGGCCGG 
ACTTCGTCCG TCTTTCCTCA GCCCACCAGC CCTGCTTTCC TCAACACTGG CAACATGAGA 
AGCATCTCAG GGACCGGAGT GACCATATTC GTCGCCCTGT ACGACTATGA GGCCAGGACA 
GGGGATGACC TCACCTTCAC CAAAGGCGAG AAGTTCCACA TCCTGAACAA TACGGAGTAT 
GACTGGTGGG AGGCTCGCTC CCTGAGCTCC GGACACAGAG GCTATGTTCC CAGCAACTAT 
GTTGCTCCTG TGGATTCCAT CCAGGCTGAA GAGTGGTACT TCGGAAAGAT CAGTAGAAAG 
GATGCAGAGA GGCAGCTTCT GTCCTCTGGT AACCCCCAGG GGGCCTTTCT CATTCGGGAA 
AGCGAGACCA CCAAAGGGGC CTACTCCCTG TCCATCCGTG ACTGGGACCA GAACAGAGGC 
GATCACATAA AGCATTATAA GATCCGAAAG CTGGACACGG GCGGCTACTA CATCACCACA 
CGGGCCCAGT TTGACTCCAT ACAGGACCTA GTGCGGCACT ACATGGAAGT GAATGATGGT 
CTGTGCTACT TGCTTACGGC GCCTTGTACC ACCACTAAGC CCCAGACTCT AGGCCTGGCC 
AAGGATGCCT GGGAGATCGA CCGGAACTCC ATAGCACTGG AACGCAGGCT GGGCACCGGC 
TGCTTTGGAG ATGTGTGGCT GGGCACATGG AACTGCAGCA CAAAGGTGGC AGTGAAGACG 
CTGAAGCCGG GCACCATGTC CCCGAAGGCA TTCCTGGAGG AGGCACAGAT CATGAAGCTG 
CTGAGGCACG ACAAGCTGGT GCAGCTGTAT GCGGTGGTGT CGGAGGAACC CATTTATATT 
GTGACAGAGT TCATGTGCTA TGGTAGCTTG CTGGATTTCC TAAAGGATCG AGAAGGTCAG 
AACTTGATGC TGCCCCATCT AGTGGACATG GCTGCCCAGG TAGCCGAGGG CATGGCCTAC 
ATGGAACGCA TGAACTATAT CCACCGAGAC TTGAGGGCAG CCAACATCCT GGTGGGGGAA 
TACCTAATAT GCAAGATCGC TGACTTCGGG CTGGCACGCC TCATAGAGGA CAATGAGTAT 
AACCCCCAAC AAGGAACCAA GTTCCCCATC AAGTGGACAG CCCCAGAGGC CGCCCTCTTT 
GGCAGATTCA CTGTCAAATC AGACGTGTGG TCCTTTGGGA TTCTGCTCAC TGAACTGATC 
ACCAAGGGCA GAGTTCCCTA CCCAGGTATG AACAACCGGG AAGTGTTGGA ACAGGTGGAG 
CATGGCTACC ACATGCCGTG CCCTCCAGGA TGTCCTGCAT CCCTGTATGA GGTCATGGAG 
CAGGCGTGGC GCCTGGATCC AGAGGAGAGG CCCACCTTTG AGTACCTGCA GTCTTTCCTG 
GAAGACTATT TCACCTCCAC AGAACCACAG TACCAGCCTG GAGACCAGAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006538607.1
CDS	650..2203
Translation	MGCVFCKKLEPASKEDVGLEGDFRSQTAEERYFPDPTQGRTSSVFPQPTSPAFLNTGNMRSISGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGHRGYVPSNYVAPVDSIQAEEWYFGKISRKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDTGGYYITTRAQFDSIQDLVRHYMEVNDGLCYLLTAPCTTTKPQTLGLAKDAWEIDRNSIALERRLGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQT

Target ORF information:

RefSeq Version	XM_006538544.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006538544.3

ORF Insert Sequence:

ATGGGCTGTG TGTTCTGCAA GAAGTTGGAG CCTGCATCCA AGGAGGATGT GGGCCTGGAA 
GGGGACTTCC GGAGCCAAAC GGCTGAAGAA CGCTATTTCC CTGACCCCAC TCAAGGCCGG 
ACTTCGTCCG TCTTTCCTCA GCCCACCAGC CCTGCTTTCC TCAACACTGG CAACATGAGA 
AGCATCTCAG GGACCGGAGT GACCATATTC GTCGCCCTGT ACGACTATGA GGCCAGGACA 
GGGGATGACC TCACCTTCAC CAAAGGCGAG AAGTTCCACA TCCTGAACAA TACGGAGTAT 
GACTGGTGGG AGGCTCGCTC CCTGAGCTCC GGACACAGAG GCTATGTTCC CAGCAACTAT 
GTTGCTCCTG TGGATTCCAT CCAGGCTGAA GAGTGGTACT TCGGAAAGAT CAGTAGAAAG 
GATGCAGAGA GGCAGCTTCT GTCCTCTGGT AACCCCCAGG GGGCCTTTCT CATTCGGGAA 
AGCGAGACCA CCAAAGGGGC CTACTCCCTG TCCATCCGTG ACTGGGACCA GAACAGAGGC 
GATCACATAA AGCATTATAA GATCCGAAAG CTGGACACGG GCGGCTACTA CATCACCACA 
CGGGCCCAGT TTGACTCCAT ACAGGACCTA GTGCGGCACT ACATGGAAGT GAATGATGGT 
CTGTGCTACT TGCTTACGGC GCCTTGTACC ACCACTAAGC CCCAGACTCT AGGCCTGGCC 
AAGGATGCCT GGGAGATCGA CCGGAACTCC ATAGCACTGG AACGCAGGCT GGGCACCGGC 
TGCTTTGGAG ATGTGTGGCT GGGCACATGG AACTGCAGCA CAAAGGTGGC AGTGAAGACG 
CTGAAGCCGG GCACCATGTC CCCGAAGGCA TTCCTGGAGG AGGCACAGAT CATGAAGCTG 
CTGAGGCACG ACAAGCTGGT GCAGCTGTAT GCGGTGGTGT CGGAGGAACC CATTTATATT 
GTGACAGAGT TCATGTGCTA TGGTAGCTTG CTGGATTTCC TAAAGGATCG AGAAGGTCAG 
AACTTGATGC TGCCCCATCT AGTGGACATG GCTGCCCAGG TAGCCGAGGG CATGGCCTAC 
ATGGAACGCA TGAACTATAT CCACCGAGAC TTGAGGGCAG CCAACATCCT GGTGGGGGAA 
TACCTAATAT GCAAGATCGC TGACTTCGGG CTGGCACGCC TCATAGAGGA CAATGAGTAT 
AACCCCCAAC AAGGAACCAA GTTCCCCATC AAGTGGACAG CCCCAGAGGC CGCCCTCTTT 
GGCAGATTCA CTGTCAAATC AGACGTGTGG TCCTTTGGGA TTCTGCTCAC TGAACTGATC 
ACCAAGGGCA GAGTTCCCTA CCCAGGTATG AACAACCGGG AAGTGTTGGA ACAGGTGGAG 
CATGGCTACC ACATGCCGTG CCCTCCAGGA TGTCCTGCAT CCCTGTATGA GGTCATGGAG 
CAGGCGTGGC GCCTGGATCC AGAGGAGAGG CCCACCTTTG AGTACCTGCA GTCTTTCCTG 
GAAGACTATT TCACCTCCAC AGAACCACAG TACCAGCCTG GAGACCAGAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgr ( XM_006538545.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006538608.1 Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu22496
Clone ID Related Accession (Same CDS sequence)	XM_006538544.3 , XM_006538545.4 , XM_006538545.3 , XM_006538544.4 , NM_010208.4
Accession Version	XM_006538545.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	tyrosine-protein kinase Fgr isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006538545.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCTGTG TGTTCTGCAA GAAGTTGGAG CCTGCATCCA AGGAGGATGT GGGCCTGGAA 
GGGGACTTCC GGAGCCAAAC GGCTGAAGAA CGCTATTTCC CTGACCCCAC TCAAGGCCGG 
ACTTCGTCCG TCTTTCCTCA GCCCACCAGC CCTGCTTTCC TCAACACTGG CAACATGAGA 
AGCATCTCAG GGACCGGAGT GACCATATTC GTCGCCCTGT ACGACTATGA GGCCAGGACA 
GGGGATGACC TCACCTTCAC CAAAGGCGAG AAGTTCCACA TCCTGAACAA TACGGAGTAT 
GACTGGTGGG AGGCTCGCTC CCTGAGCTCC GGACACAGAG GCTATGTTCC CAGCAACTAT 
GTTGCTCCTG TGGATTCCAT CCAGGCTGAA GAGTGGTACT TCGGAAAGAT CAGTAGAAAG 
GATGCAGAGA GGCAGCTTCT GTCCTCTGGT AACCCCCAGG GGGCCTTTCT CATTCGGGAA 
AGCGAGACCA CCAAAGGGGC CTACTCCCTG TCCATCCGTG ACTGGGACCA GAACAGAGGC 
GATCACATAA AGCATTATAA GATCCGAAAG CTGGACACGG GCGGCTACTA CATCACCACA 
CGGGCCCAGT TTGACTCCAT ACAGGACCTA GTGCGGCACT ACATGGAAGT GAATGATGGT 
CTGTGCTACT TGCTTACGGC GCCTTGTACC ACCACTAAGC CCCAGACTCT AGGCCTGGCC 
AAGGATGCCT GGGAGATCGA CCGGAACTCC ATAGCACTGG AACGCAGGCT GGGCACCGGC 
TGCTTTGGAG ATGTGTGGCT GGGCACATGG AACTGCAGCA CAAAGGTGGC AGTGAAGACG 
CTGAAGCCGG GCACCATGTC CCCGAAGGCA TTCCTGGAGG AGGCACAGAT CATGAAGCTG 
CTGAGGCACG ACAAGCTGGT GCAGCTGTAT GCGGTGGTGT CGGAGGAACC CATTTATATT 
GTGACAGAGT TCATGTGCTA TGGTAGCTTG CTGGATTTCC TAAAGGATCG AGAAGGTCAG 
AACTTGATGC TGCCCCATCT AGTGGACATG GCTGCCCAGG TAGCCGAGGG CATGGCCTAC 
ATGGAACGCA TGAACTATAT CCACCGAGAC TTGAGGGCAG CCAACATCCT GGTGGGGGAA 
TACCTAATAT GCAAGATCGC TGACTTCGGG CTGGCACGCC TCATAGAGGA CAATGAGTAT 
AACCCCCAAC AAGGAACCAA GTTCCCCATC AAGTGGACAG CCCCAGAGGC CGCCCTCTTT 
GGCAGATTCA CTGTCAAATC AGACGTGTGG TCCTTTGGGA TTCTGCTCAC TGAACTGATC 
ACCAAGGGCA GAGTTCCCTA CCCAGGTATG AACAACCGGG AAGTGTTGGA ACAGGTGGAG 
CATGGCTACC ACATGCCGTG CCCTCCAGGA TGTCCTGCAT CCCTGTATGA GGTCATGGAG 
CAGGCGTGGC GCCTGGATCC AGAGGAGAGG CCCACCTTTG AGTACCTGCA GTCTTTCCTG 
GAAGACTATT TCACCTCCAC AGAACCACAG TACCAGCCTG GAGACCAGAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006538608.1
CDS	494..2047
Translation	MGCVFCKKLEPASKEDVGLEGDFRSQTAEERYFPDPTQGRTSSVFPQPTSPAFLNTGNMRSISGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGHRGYVPSNYVAPVDSIQAEEWYFGKISRKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDTGGYYITTRAQFDSIQDLVRHYMEVNDGLCYLLTAPCTTTKPQTLGLAKDAWEIDRNSIALERRLGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQT

Target ORF information:

RefSeq Version	XM_006538545.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006538545.3

ORF Insert Sequence:

ATGGGCTGTG TGTTCTGCAA GAAGTTGGAG CCTGCATCCA AGGAGGATGT GGGCCTGGAA 
GGGGACTTCC GGAGCCAAAC GGCTGAAGAA CGCTATTTCC CTGACCCCAC TCAAGGCCGG 
ACTTCGTCCG TCTTTCCTCA GCCCACCAGC CCTGCTTTCC TCAACACTGG CAACATGAGA 
AGCATCTCAG GGACCGGAGT GACCATATTC GTCGCCCTGT ACGACTATGA GGCCAGGACA 
GGGGATGACC TCACCTTCAC CAAAGGCGAG AAGTTCCACA TCCTGAACAA TACGGAGTAT 
GACTGGTGGG AGGCTCGCTC CCTGAGCTCC GGACACAGAG GCTATGTTCC CAGCAACTAT 
GTTGCTCCTG TGGATTCCAT CCAGGCTGAA GAGTGGTACT TCGGAAAGAT CAGTAGAAAG 
GATGCAGAGA GGCAGCTTCT GTCCTCTGGT AACCCCCAGG GGGCCTTTCT CATTCGGGAA 
AGCGAGACCA CCAAAGGGGC CTACTCCCTG TCCATCCGTG ACTGGGACCA GAACAGAGGC 
GATCACATAA AGCATTATAA GATCCGAAAG CTGGACACGG GCGGCTACTA CATCACCACA 
CGGGCCCAGT TTGACTCCAT ACAGGACCTA GTGCGGCACT ACATGGAAGT GAATGATGGT 
CTGTGCTACT TGCTTACGGC GCCTTGTACC ACCACTAAGC CCCAGACTCT AGGCCTGGCC 
AAGGATGCCT GGGAGATCGA CCGGAACTCC ATAGCACTGG AACGCAGGCT GGGCACCGGC 
TGCTTTGGAG ATGTGTGGCT GGGCACATGG AACTGCAGCA CAAAGGTGGC AGTGAAGACG 
CTGAAGCCGG GCACCATGTC CCCGAAGGCA TTCCTGGAGG AGGCACAGAT CATGAAGCTG 
CTGAGGCACG ACAAGCTGGT GCAGCTGTAT GCGGTGGTGT CGGAGGAACC CATTTATATT 
GTGACAGAGT TCATGTGCTA TGGTAGCTTG CTGGATTTCC TAAAGGATCG AGAAGGTCAG 
AACTTGATGC TGCCCCATCT AGTGGACATG GCTGCCCAGG TAGCCGAGGG CATGGCCTAC 
ATGGAACGCA TGAACTATAT CCACCGAGAC TTGAGGGCAG CCAACATCCT GGTGGGGGAA 
TACCTAATAT GCAAGATCGC TGACTTCGGG CTGGCACGCC TCATAGAGGA CAATGAGTAT 
AACCCCCAAC AAGGAACCAA GTTCCCCATC AAGTGGACAG CCCCAGAGGC CGCCCTCTTT 
GGCAGATTCA CTGTCAAATC AGACGTGTGG TCCTTTGGGA TTCTGCTCAC TGAACTGATC 
ACCAAGGGCA GAGTTCCCTA CCCAGGTATG AACAACCGGG AAGTGTTGGA ACAGGTGGAG 
CATGGCTACC ACATGCCGTG CCCTCCAGGA TGTCCTGCAT CCCTGTATGA GGTCATGGAG 
CAGGCGTGGC GCCTGGATCC AGAGGAGAGG CCCACCTTTG AGTACCTGCA GTCTTTCCTG 
GAAGACTATT TCACCTCCAC AGAACCACAG TACCAGCCTG GAGACCAGAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgr ( XM_006538545.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006538608.1 Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu22496
Clone ID Related Accession (Same CDS sequence)	XM_006538544.3 , XM_006538545.4 , XM_006538545.3 , XM_006538544.4 , NM_010208.4
Accession Version	XM_006538545.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	tyrosine-protein kinase Fgr isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006538545.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCTGTG TGTTCTGCAA GAAGTTGGAG CCTGCATCCA AGGAGGATGT GGGCCTGGAA 
GGGGACTTCC GGAGCCAAAC GGCTGAAGAA CGCTATTTCC CTGACCCCAC TCAAGGCCGG 
ACTTCGTCCG TCTTTCCTCA GCCCACCAGC CCTGCTTTCC TCAACACTGG CAACATGAGA 
AGCATCTCAG GGACCGGAGT GACCATATTC GTCGCCCTGT ACGACTATGA GGCCAGGACA 
GGGGATGACC TCACCTTCAC CAAAGGCGAG AAGTTCCACA TCCTGAACAA TACGGAGTAT 
GACTGGTGGG AGGCTCGCTC CCTGAGCTCC GGACACAGAG GCTATGTTCC CAGCAACTAT 
GTTGCTCCTG TGGATTCCAT CCAGGCTGAA GAGTGGTACT TCGGAAAGAT CAGTAGAAAG 
GATGCAGAGA GGCAGCTTCT GTCCTCTGGT AACCCCCAGG GGGCCTTTCT CATTCGGGAA 
AGCGAGACCA CCAAAGGGGC CTACTCCCTG TCCATCCGTG ACTGGGACCA GAACAGAGGC 
GATCACATAA AGCATTATAA GATCCGAAAG CTGGACACGG GCGGCTACTA CATCACCACA 
CGGGCCCAGT TTGACTCCAT ACAGGACCTA GTGCGGCACT ACATGGAAGT GAATGATGGT 
CTGTGCTACT TGCTTACGGC GCCTTGTACC ACCACTAAGC CCCAGACTCT AGGCCTGGCC 
AAGGATGCCT GGGAGATCGA CCGGAACTCC ATAGCACTGG AACGCAGGCT GGGCACCGGC 
TGCTTTGGAG ATGTGTGGCT GGGCACATGG AACTGCAGCA CAAAGGTGGC AGTGAAGACG 
CTGAAGCCGG GCACCATGTC CCCGAAGGCA TTCCTGGAGG AGGCACAGAT CATGAAGCTG 
CTGAGGCACG ACAAGCTGGT GCAGCTGTAT GCGGTGGTGT CGGAGGAACC CATTTATATT 
GTGACAGAGT TCATGTGCTA TGGTAGCTTG CTGGATTTCC TAAAGGATCG AGAAGGTCAG 
AACTTGATGC TGCCCCATCT AGTGGACATG GCTGCCCAGG TAGCCGAGGG CATGGCCTAC 
ATGGAACGCA TGAACTATAT CCACCGAGAC TTGAGGGCAG CCAACATCCT GGTGGGGGAA 
TACCTAATAT GCAAGATCGC TGACTTCGGG CTGGCACGCC TCATAGAGGA CAATGAGTAT 
AACCCCCAAC AAGGAACCAA GTTCCCCATC AAGTGGACAG CCCCAGAGGC CGCCCTCTTT 
GGCAGATTCA CTGTCAAATC AGACGTGTGG TCCTTTGGGA TTCTGCTCAC TGAACTGATC 
ACCAAGGGCA GAGTTCCCTA CCCAGGTATG AACAACCGGG AAGTGTTGGA ACAGGTGGAG 
CATGGCTACC ACATGCCGTG CCCTCCAGGA TGTCCTGCAT CCCTGTATGA GGTCATGGAG 
CAGGCGTGGC GCCTGGATCC AGAGGAGAGG CCCACCTTTG AGTACCTGCA GTCTTTCCTG 
GAAGACTATT TCACCTCCAC AGAACCACAG TACCAGCCTG GAGACCAGAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006538608.1
CDS	494..2047
Translation	MGCVFCKKLEPASKEDVGLEGDFRSQTAEERYFPDPTQGRTSSVFPQPTSPAFLNTGNMRSISGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGHRGYVPSNYVAPVDSIQAEEWYFGKISRKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDTGGYYITTRAQFDSIQDLVRHYMEVNDGLCYLLTAPCTTTKPQTLGLAKDAWEIDRNSIALERRLGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQT

Target ORF information:

RefSeq Version	XM_006538545.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006538545.4

ORF Insert Sequence:

ATGGGCTGTG TGTTCTGCAA GAAGTTGGAG CCTGCATCCA AGGAGGATGT GGGCCTGGAA 
GGGGACTTCC GGAGCCAAAC GGCTGAAGAA CGCTATTTCC CTGACCCCAC TCAAGGCCGG 
ACTTCGTCCG TCTTTCCTCA GCCCACCAGC CCTGCTTTCC TCAACACTGG CAACATGAGA 
AGCATCTCAG GGACCGGAGT GACCATATTC GTCGCCCTGT ACGACTATGA GGCCAGGACA 
GGGGATGACC TCACCTTCAC CAAAGGCGAG AAGTTCCACA TCCTGAACAA TACGGAGTAT 
GACTGGTGGG AGGCTCGCTC CCTGAGCTCC GGACACAGAG GCTATGTTCC CAGCAACTAT 
GTTGCTCCTG TGGATTCCAT CCAGGCTGAA GAGTGGTACT TCGGAAAGAT CAGTAGAAAG 
GATGCAGAGA GGCAGCTTCT GTCCTCTGGT AACCCCCAGG GGGCCTTTCT CATTCGGGAA 
AGCGAGACCA CCAAAGGGGC CTACTCCCTG TCCATCCGTG ACTGGGACCA GAACAGAGGC 
GATCACATAA AGCATTATAA GATCCGAAAG CTGGACACGG GCGGCTACTA CATCACCACA 
CGGGCCCAGT TTGACTCCAT ACAGGACCTA GTGCGGCACT ACATGGAAGT GAATGATGGT 
CTGTGCTACT TGCTTACGGC GCCTTGTACC ACCACTAAGC CCCAGACTCT AGGCCTGGCC 
AAGGATGCCT GGGAGATCGA CCGGAACTCC ATAGCACTGG AACGCAGGCT GGGCACCGGC 
TGCTTTGGAG ATGTGTGGCT GGGCACATGG AACTGCAGCA CAAAGGTGGC AGTGAAGACG 
CTGAAGCCGG GCACCATGTC CCCGAAGGCA TTCCTGGAGG AGGCACAGAT CATGAAGCTG 
CTGAGGCACG ACAAGCTGGT GCAGCTGTAT GCGGTGGTGT CGGAGGAACC CATTTATATT 
GTGACAGAGT TCATGTGCTA TGGTAGCTTG CTGGATTTCC TAAAGGATCG AGAAGGTCAG 
AACTTGATGC TGCCCCATCT AGTGGACATG GCTGCCCAGG TAGCCGAGGG CATGGCCTAC 
ATGGAACGCA TGAACTATAT CCACCGAGAC TTGAGGGCAG CCAACATCCT GGTGGGGGAA 
TACCTAATAT GCAAGATCGC TGACTTCGGG CTGGCACGCC TCATAGAGGA CAATGAGTAT 
AACCCCCAAC AAGGAACCAA GTTCCCCATC AAGTGGACAG CCCCAGAGGC CGCCCTCTTT 
GGCAGATTCA CTGTCAAATC AGACGTGTGG TCCTTTGGGA TTCTGCTCAC TGAACTGATC 
ACCAAGGGCA GAGTTCCCTA CCCAGGTATG AACAACCGGG AAGTGTTGGA ACAGGTGGAG 
CATGGCTACC ACATGCCGTG CCCTCCAGGA TGTCCTGCAT CCCTGTATGA GGTCATGGAG 
CAGGCGTGGC GCCTGGATCC AGAGGAGAGG CCCACCTTTG AGTACCTGCA GTCTTTCCTG 
GAAGACTATT TCACCTCCAC AGAACCACAG TACCAGCCTG GAGACCAGAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fgr ( XM_006538544.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006538607.1 Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu22496
Clone ID Related Accession (Same CDS sequence)	XM_006538544.3 , XM_006538545.4 , XM_006538545.3 , XM_006538544.4 , NM_010208.4
Accession Version	XM_006538544.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	tyrosine-protein kinase Fgr isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006538544.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCTGTG TGTTCTGCAA GAAGTTGGAG CCTGCATCCA AGGAGGATGT GGGCCTGGAA 
GGGGACTTCC GGAGCCAAAC GGCTGAAGAA CGCTATTTCC CTGACCCCAC TCAAGGCCGG 
ACTTCGTCCG TCTTTCCTCA GCCCACCAGC CCTGCTTTCC TCAACACTGG CAACATGAGA 
AGCATCTCAG GGACCGGAGT GACCATATTC GTCGCCCTGT ACGACTATGA GGCCAGGACA 
GGGGATGACC TCACCTTCAC CAAAGGCGAG AAGTTCCACA TCCTGAACAA TACGGAGTAT 
GACTGGTGGG AGGCTCGCTC CCTGAGCTCC GGACACAGAG GCTATGTTCC CAGCAACTAT 
GTTGCTCCTG TGGATTCCAT CCAGGCTGAA GAGTGGTACT TCGGAAAGAT CAGTAGAAAG 
GATGCAGAGA GGCAGCTTCT GTCCTCTGGT AACCCCCAGG GGGCCTTTCT CATTCGGGAA 
AGCGAGACCA CCAAAGGGGC CTACTCCCTG TCCATCCGTG ACTGGGACCA GAACAGAGGC 
GATCACATAA AGCATTATAA GATCCGAAAG CTGGACACGG GCGGCTACTA CATCACCACA 
CGGGCCCAGT TTGACTCCAT ACAGGACCTA GTGCGGCACT ACATGGAAGT GAATGATGGT 
CTGTGCTACT TGCTTACGGC GCCTTGTACC ACCACTAAGC CCCAGACTCT AGGCCTGGCC 
AAGGATGCCT GGGAGATCGA CCGGAACTCC ATAGCACTGG AACGCAGGCT GGGCACCGGC 
TGCTTTGGAG ATGTGTGGCT GGGCACATGG AACTGCAGCA CAAAGGTGGC AGTGAAGACG 
CTGAAGCCGG GCACCATGTC CCCGAAGGCA TTCCTGGAGG AGGCACAGAT CATGAAGCTG 
CTGAGGCACG ACAAGCTGGT GCAGCTGTAT GCGGTGGTGT CGGAGGAACC CATTTATATT 
GTGACAGAGT TCATGTGCTA TGGTAGCTTG CTGGATTTCC TAAAGGATCG AGAAGGTCAG 
AACTTGATGC TGCCCCATCT AGTGGACATG GCTGCCCAGG TAGCCGAGGG CATGGCCTAC 
ATGGAACGCA TGAACTATAT CCACCGAGAC TTGAGGGCAG CCAACATCCT GGTGGGGGAA 
TACCTAATAT GCAAGATCGC TGACTTCGGG CTGGCACGCC TCATAGAGGA CAATGAGTAT 
AACCCCCAAC AAGGAACCAA GTTCCCCATC AAGTGGACAG CCCCAGAGGC CGCCCTCTTT 
GGCAGATTCA CTGTCAAATC AGACGTGTGG TCCTTTGGGA TTCTGCTCAC TGAACTGATC 
ACCAAGGGCA GAGTTCCCTA CCCAGGTATG AACAACCGGG AAGTGTTGGA ACAGGTGGAG 
CATGGCTACC ACATGCCGTG CCCTCCAGGA TGTCCTGCAT CCCTGTATGA GGTCATGGAG 
CAGGCGTGGC GCCTGGATCC AGAGGAGAGG CCCACCTTTG AGTACCTGCA GTCTTTCCTG 
GAAGACTATT TCACCTCCAC AGAACCACAG TACCAGCCTG GAGACCAGAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006538607.1
CDS	364..1917
Translation	MGCVFCKKLEPASKEDVGLEGDFRSQTAEERYFPDPTQGRTSSVFPQPTSPAFLNTGNMRSISGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGHRGYVPSNYVAPVDSIQAEEWYFGKISRKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDTGGYYITTRAQFDSIQDLVRHYMEVNDGLCYLLTAPCTTTKPQTLGLAKDAWEIDRNSIALERRLGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQT

Target ORF information:

RefSeq Version	XM_006538544.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus FGR proto-oncogene, Src family tyrosine kinase (Fgr), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006538544.4

ORF Insert Sequence:

ATGGGCTGTG TGTTCTGCAA GAAGTTGGAG CCTGCATCCA AGGAGGATGT GGGCCTGGAA 
GGGGACTTCC GGAGCCAAAC GGCTGAAGAA CGCTATTTCC CTGACCCCAC TCAAGGCCGG 
ACTTCGTCCG TCTTTCCTCA GCCCACCAGC CCTGCTTTCC TCAACACTGG CAACATGAGA 
AGCATCTCAG GGACCGGAGT GACCATATTC GTCGCCCTGT ACGACTATGA GGCCAGGACA 
GGGGATGACC TCACCTTCAC CAAAGGCGAG AAGTTCCACA TCCTGAACAA TACGGAGTAT 
GACTGGTGGG AGGCTCGCTC CCTGAGCTCC GGACACAGAG GCTATGTTCC CAGCAACTAT 
GTTGCTCCTG TGGATTCCAT CCAGGCTGAA GAGTGGTACT TCGGAAAGAT CAGTAGAAAG 
GATGCAGAGA GGCAGCTTCT GTCCTCTGGT AACCCCCAGG GGGCCTTTCT CATTCGGGAA 
AGCGAGACCA CCAAAGGGGC CTACTCCCTG TCCATCCGTG ACTGGGACCA GAACAGAGGC 
GATCACATAA AGCATTATAA GATCCGAAAG CTGGACACGG GCGGCTACTA CATCACCACA 
CGGGCCCAGT TTGACTCCAT ACAGGACCTA GTGCGGCACT ACATGGAAGT GAATGATGGT 
CTGTGCTACT TGCTTACGGC GCCTTGTACC ACCACTAAGC CCCAGACTCT AGGCCTGGCC 
AAGGATGCCT GGGAGATCGA CCGGAACTCC ATAGCACTGG AACGCAGGCT GGGCACCGGC 
TGCTTTGGAG ATGTGTGGCT GGGCACATGG AACTGCAGCA CAAAGGTGGC AGTGAAGACG 
CTGAAGCCGG GCACCATGTC CCCGAAGGCA TTCCTGGAGG AGGCACAGAT CATGAAGCTG 
CTGAGGCACG ACAAGCTGGT GCAGCTGTAT GCGGTGGTGT CGGAGGAACC CATTTATATT 
GTGACAGAGT TCATGTGCTA TGGTAGCTTG CTGGATTTCC TAAAGGATCG AGAAGGTCAG 
AACTTGATGC TGCCCCATCT AGTGGACATG GCTGCCCAGG TAGCCGAGGG CATGGCCTAC 
ATGGAACGCA TGAACTATAT CCACCGAGAC TTGAGGGCAG CCAACATCCT GGTGGGGGAA 
TACCTAATAT GCAAGATCGC TGACTTCGGG CTGGCACGCC TCATAGAGGA CAATGAGTAT 
AACCCCCAAC AAGGAACCAA GTTCCCCATC AAGTGGACAG CCCCAGAGGC CGCCCTCTTT 
GGCAGATTCA CTGTCAAATC AGACGTGTGG TCCTTTGGGA TTCTGCTCAC TGAACTGATC 
ACCAAGGGCA GAGTTCCCTA CCCAGGTATG AACAACCGGG AAGTGTTGGA ACAGGTGGAG 
CATGGCTACC ACATGCCGTG CCCTCCAGGA TGTCCTGCAT CCCTGTATGA GGTCATGGAG 
CAGGCGTGGC GCCTGGATCC AGAGGAGAGG CCCACCTTTG AGTACCTGCA GTCTTTCCTG 
GAAGACTATT TCACCTCCAC AGAACCACAG TACCAGCCTG GAGACCAGAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Syk Tyrosine Kinase Is Required for Skin Inflammation in an In?Vivo Mouse Model of?Epidermolysis Bullosa Acquisita.
The Journal of investigative dermatology137(10)2131-2139(2017 Oct)
N?meth T,Virtic O,Sitaru C,M?csai A

The Src kinases Hck, Fgr and Lyn activate Arg to facilitate IgG-mediated phagocytosis and Leishmania infection.
Journal of cell science129(16)3130-43(2016 08)
Wetzel DM,Rhodes EL,Li S,McMahon-Pratt D,Koleske AJ

Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo.
Nature communications711004(2016 Apr)
N?meth T,Futosi K,Sitaru C,Ruland J,M?csai A

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Fgr cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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