NKAIN1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NKAIN1
Entrez Gene ID	79570
Full Name	sodium/potassium transporting ATPase interacting 1
Synonyms	FAM77C
General protein information	Preferred Names sodium/potassium transporting ATPase interacting 1 Names sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 1 Na+/K+ transporting ATPase interacting 1 family with sequence similarity 77, member C
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p35.2
Summary	NKAIN1 is a member of a family of mammalian proteins with similarity to Drosophila Nkain and interacts with the beta subunit of Na,K-ATPase (ATP1B1; MIM 182330) (Gorokhova et al., 2007 [PubMed 17606467]).[supplied by OMIM, Jun 2009].
Disorder MIM:	612871

mRNA and Protein(s)

mRNA	Protein	Name
NM_024522.2	NP_078798.2	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 precursor
XM_017002320.1	XP_016857809.1	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 isoform X1
NM_024522.3	NP_078798.2	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Nkain1	XP_006239052.1
Gallus gallus (chicken)	NKAIN1	XP_001231908.3
Xenopus tropicalis (tropical clawed frog)	nkain1	NP_001072596.1
Mus musculus (house mouse)	Nkain1	NP_080274.2
Danio rerio (zebrafish)	nkain1	NP_956839.1
Pan troglodytes (chimpanzee)	NKAIN1	XP_530112.3
	LOC704595	XP_001092961.2
Canis lupus familiaris (dog)	NKAIN1	XP_854733.3
Homo sapiens (human)	NKAIN1	NP_078798.2
Bos taurus (cattle)	NKAIN1	XP_002685710.2

Gene Ontology
Bibliography

Related articles in PubMed

NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent.
Zuo L, Wang K, Zhang XY, Krystal JH, Li CS, Zhang F, Zhang H, Luo X
Drug and alcohol dependence129(3)254-64(2013 May)

A novel family of transmembrane proteins interacting with beta subunits of the Na,K-ATPase.
Gorokhova S, Bibert S, Geering K, Heintz N
Human molecular genetics16(20)2394-410(2007 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NKAIN1-SERINC2 gene expression is associated with alcohol dependence in subjects of European descent.
Title: NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent.

The following NKAIN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NKAIN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27119	NM_024522.3 Latest version!	Homo sapiens sodium/potassium transporting ATPase interacting 1 (NKAIN1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu90519	XM_017002320.1 Latest version!	Homo sapiens sodium/potassium transporting ATPase interacting 1 (NKAIN1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu27119	NM_024522.2	Homo sapiens sodium/potassium transporting ATPase interacting 1 (NKAIN1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NKAIN1 ( NM_024522.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_078798.2 Homo sapiens sodium/potassium transporting ATPase interacting 1 (NKAIN1), mRNA.

Price & Availability↑

CloneID	OHu27119
Clone ID Related Accession (Same CDS sequence)	NM_024522.2 , NM_024522.3
Accession Version	NM_024522.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB499136.2, AI884789.1, AK299507.1, AK298874.1, AK022712.1 and AL832547.1. On May 20, 2010 this sequence version replaced NM_024522.1. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.195151.1, SRR1803617.85303.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267762 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT GCAGCGGGCG CTGCACGCTG GTCGCCTTCT GCTGCCTGCA GCTGGTGGCT 
GCGCTGGAGC GGCAGATCTT TGACTTCCTG GGCTACCAGT GGGCTCCCAT CCTAGCCAAC 
TTCCTGCACA TCATGGCAGT CATCCTGGGC ATCTTTGGCA CCGTGCAGTA CCGCTCCCGG 
TACCTCATCC TGTATGCAGC CTGGCTGGTG CTCTGGGTTG GCTGGAATGC ATTTATCATC 
TGCTTCTACT TGGAGGTTGG ACAGCTGTCC CAGGACCGGG ACTTCATCAT GACCTTCAAC 
ACATCCCTGC ACCGCTCCTG GTGGATGGAG AATGGGCCAG GCTGCCTGGT GACACCTGTT 
CTGAACTCCC GCCTGGCTCT GGAGGACCAC CATGTCATCT CTGTCACTGG CTGCCTGCTT 
GACTACCCCT ACATTGAAGC CCTCAGCAGC GCCCTGCAGA TCTTCCTGGC ACTGTTCGGC 
TTCGTGTTCG CCTGCTACGT GAGCAAAGTG TTCCTGGAGG AGGAGGACAG CTTTGACTTC 
ATCGGCGGCT TTGACTCCTA CGGATACCAG GCGCCCCAGA AGACGTCGCA TTTACAGCTG 
CAGCCTCTGT ACACGTCGGG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078798.2
CDS	341..964
Translation	MGKCSGRCTLVAFCCLQLVAALERQIFDFLGYQWAPILANFLHIMAVILGIFGTVQYRSRYLILYAAWLVLWVGWNAFIICFYLEVGQLSQDRDFIMTFNTSLHRSWWMENGPGCLVTPVLNSRLALEDHHVISVTGCLLDYPYIEALSSALQIFLALFGFVFACYVSKVFLEEEDSFDFIGGFDSYGYQAPQKTSHLQLQPLYTSG

Target ORF information:

RefSeq Version	NM_024522.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium/potassium transporting ATPase interacting 1 (NKAIN1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024522.2

ORF Insert Sequence:

ATGGGCAAGT GCAGCGGGCG CTGCACGCTG GTCGCCTTCT GCTGCCTGCA GCTGGTGGCT 
GCGCTGGAGC GGCAGATCTT TGACTTCCTG GGCTACCAGT GGGCTCCCAT CCTAGCCAAC 
TTCCTGCACA TCATGGCAGT CATCCTGGGC ATCTTTGGCA CCGTGCAGTA CCGCTCCCGG 
TACCTCATCC TGTATGCAGC CTGGCTGGTG CTCTGGGTTG GCTGGAATGC ATTTATCATC 
TGCTTCTACT TGGAGGTTGG ACAGCTGTCC CAGGACCGGG ACTTCATCAT GACCTTCAAC 
ACATCCCTGC ACCGCTCCTG GTGGATGGAG AATGGGCCAG GCTGCCTGGT GACACCTGTT 
CTGAACTCCC GCCTGGCTCT GGAGGACCAC CATGTCATCT CTGTCACTGG CTGCCTGCTT 
GACTACCCCT ACATTGAAGC CCTCAGCAGC GCCCTGCAGA TCTTCCTGGC ACTGTTCGGC 
TTCGTGTTCG CCTGCTACGT GAGCAAAGTG TTCCTGGAGG AGGAGGACAG CTTTGACTTC 
ATCGGCGGCT TTGACTCCTA CGGATACCAG GCGCCCCAGA AGACGTCGCA TTTACAGCTG 
CAGCCTCTGT ACACGTCGGG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NKAIN1 ( NM_024522.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_078798.2 Homo sapiens sodium/potassium transporting ATPase interacting 1 (NKAIN1), mRNA.

Price & Availability↑

CloneID	OHu27119
Clone ID Related Accession (Same CDS sequence)	NM_024522.2 , NM_024522.3
Accession Version	NM_024522.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB499136.2, AI884789.1, AK299507.1, AK298874.1, AK022712.1 and AL832547.1. On Nov 23, 2018 this sequence version replaced NM_024522.2. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.195151.1, SRR1803617.85303.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267762 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000373736.7/ ENSP00000362841.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGCAAGT GCAGCGGGCG CTGCACGCTG GTCGCCTTCT GCTGCCTGCA GCTGGTGGCT 
GCGCTGGAGC GGCAGATCTT TGACTTCCTG GGCTACCAGT GGGCTCCCAT CCTAGCCAAC 
TTCCTGCACA TCATGGCAGT CATCCTGGGC ATCTTTGGCA CCGTGCAGTA CCGCTCCCGG 
TACCTCATCC TGTATGCAGC CTGGCTGGTG CTCTGGGTTG GCTGGAATGC ATTTATCATC 
TGCTTCTACT TGGAGGTTGG ACAGCTGTCC CAGGACCGGG ACTTCATCAT GACCTTCAAC 
ACATCCCTGC ACCGCTCCTG GTGGATGGAG AATGGGCCAG GCTGCCTGGT GACACCTGTT 
CTGAACTCCC GCCTGGCTCT GGAGGACCAC CATGTCATCT CTGTCACTGG CTGCCTGCTT 
GACTACCCCT ACATTGAAGC CCTCAGCAGC GCCCTGCAGA TCTTCCTGGC ACTGTTCGGC 
TTCGTGTTCG CCTGCTACGT GAGCAAAGTG TTCCTGGAGG AGGAGGACAG CTTTGACTTC 
ATCGGCGGCT TTGACTCCTA CGGATACCAG GCGCCCCAGA AGACGTCGCA TTTACAGCTG 
CAGCCTCTGT ACACGTCGGG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078798.2
CDS	341..964
Translation	MGKCSGRCTLVAFCCLQLVAALERQIFDFLGYQWAPILANFLHIMAVILGIFGTVQYRSRYLILYAAWLVLWVGWNAFIICFYLEVGQLSQDRDFIMTFNTSLHRSWWMENGPGCLVTPVLNSRLALEDHHVISVTGCLLDYPYIEALSSALQIFLALFGFVFACYVSKVFLEEEDSFDFIGGFDSYGYQAPQKTSHLQLQPLYTSG

Target ORF information:

RefSeq Version	NM_024522.3
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium/potassium transporting ATPase interacting 1 (NKAIN1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024522.3

ORF Insert Sequence:

ATGGGCAAGT GCAGCGGGCG CTGCACGCTG GTCGCCTTCT GCTGCCTGCA GCTGGTGGCT 
GCGCTGGAGC GGCAGATCTT TGACTTCCTG GGCTACCAGT GGGCTCCCAT CCTAGCCAAC 
TTCCTGCACA TCATGGCAGT CATCCTGGGC ATCTTTGGCA CCGTGCAGTA CCGCTCCCGG 
TACCTCATCC TGTATGCAGC CTGGCTGGTG CTCTGGGTTG GCTGGAATGC ATTTATCATC 
TGCTTCTACT TGGAGGTTGG ACAGCTGTCC CAGGACCGGG ACTTCATCAT GACCTTCAAC 
ACATCCCTGC ACCGCTCCTG GTGGATGGAG AATGGGCCAG GCTGCCTGGT GACACCTGTT 
CTGAACTCCC GCCTGGCTCT GGAGGACCAC CATGTCATCT CTGTCACTGG CTGCCTGCTT 
GACTACCCCT ACATTGAAGC CCTCAGCAGC GCCCTGCAGA TCTTCCTGGC ACTGTTCGGC 
TTCGTGTTCG CCTGCTACGT GAGCAAAGTG TTCCTGGAGG AGGAGGACAG CTTTGACTTC 
ATCGGCGGCT TTGACTCCTA CGGATACCAG GCGCCCCAGA AGACGTCGCA TTTACAGCTG 
CAGCCTCTGT ACACGTCGGG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NKAIN1 ( XM_017002320.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016857809.1 Homo sapiens sodium/potassium transporting ATPase interacting 1 (NKAIN1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu90519
Clone ID Related Accession (Same CDS sequence)	XM_017002320.1
Accession Version	XM_017002320.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAAGT GCAGCGGGCG CTGCACGCTG GTCGCCTTCT GCTGCCTGCA GCTGGTGGCT 
GCGCTGGAGC GGCAGATCTT TGACTTCCTG GGCTACCAGT GGGCTCCCAT CCTAGCCAAC 
TTCCTGCACA TCATGGCAGT CATCCTGGGC ATCTTTGGCA CCGTGCAGTA CCGCTCCCGG 
TACCTCATCC TGGACCGGGA CTTCATCATG ACCTTCAACA CATCCCTGCA CCGCTCCTGG 
TGGATGGAGA ATGGGCCAGG CTGCCTGGTG ACACCTGTTC TGAACTCCCG CCTGGCTCTG 
GAGGACCACC ATGTCATCTC TGTCACTGGC TGCCTGCTTG ACTACCCCTA CATTGAAGCC 
CTCAGCAGCG CCCTGCAGAT CTTCCTGGCA CTGTTCGGCT TCGTGTTCGC CTGCTACGTG 
AGCAAAGTGT TCCTGGAGGA GGAGGACAGC TTTGACTTCA TCGGCGGCTT TGACTCCTAC 
GGATACCAGG CGCCCCAGAA GACGTCGCAT TTACAGCTGC AGCCTCTGTA CACGTCGGGG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016857809.1
CDS	16..558
Translation	MGKCSGRCTLVAFCCLQLVAALERQIFDFLGYQWAPILANFLHIMAVILGIFGTVQYRSRYLILDRDFIMTFNTSLHRSWWMENGPGCLVTPVLNSRLALEDHHVISVTGCLLDYPYIEALSSALQIFLALFGFVFACYVSKVFLEEEDSFDFIGGFDSYGYQAPQKTSHLQLQPLYTSG

Target ORF information:

RefSeq Version	XM_017002320.1
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium/potassium transporting ATPase interacting 1 (NKAIN1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017002320.1

ORF Insert Sequence:

ATGGGCAAGT GCAGCGGGCG CTGCACGCTG GTCGCCTTCT GCTGCCTGCA GCTGGTGGCT 
GCGCTGGAGC GGCAGATCTT TGACTTCCTG GGCTACCAGT GGGCTCCCAT CCTAGCCAAC 
TTCCTGCACA TCATGGCAGT CATCCTGGGC ATCTTTGGCA CCGTGCAGTA CCGCTCCCGG 
TACCTCATCC TGGACCGGGA CTTCATCATG ACCTTCAACA CATCCCTGCA CCGCTCCTGG 
TGGATGGAGA ATGGGCCAGG CTGCCTGGTG ACACCTGTTC TGAACTCCCG CCTGGCTCTG 
GAGGACCACC ATGTCATCTC TGTCACTGGC TGCCTGCTTG ACTACCCCTA CATTGAAGCC 
CTCAGCAGCG CCCTGCAGAT CTTCCTGGCA CTGTTCGGCT TCGTGTTCGC CTGCTACGTG 
AGCAAAGTGT TCCTGGAGGA GGAGGACAGC TTTGACTTCA TCGGCGGCTT TGACTCCTAC 
GGATACCAGG CGCCCCAGAA GACGTCGCAT TTACAGCTGC AGCCTCTGTA CACGTCGGGG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent.
Drug and alcohol dependence129(3)254-64(2013 May)
Zuo L,Wang K,Zhang XY,Krystal JH,Li CS,Zhang F,Zhang H,Luo X

A novel family of transmembrane proteins interacting with beta subunits of the Na,K-ATPase.
Human molecular genetics16(20)2394-410(2007 Oct)
Gorokhova S,Bibert S,Geering K,Heintz N