GAGE2A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GAGE2A
Entrez Gene ID	729447
Full Name	G antigen 2A
Synonyms	CT4.2,GAGE-2,GAGE-2A,GAGE2
General protein information	Preferred Names G antigen 2A Names G antigen 2A/2B G antigen 2 cancer/testis antigen 4.2 cancer/testis antigen family 4, member 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp11.23
Disorder MIM:	300720

mRNA and Protein(s)

mRNA	Protein	Name
NM_001127212.1	NP_001120684.1	G antigen 2A/2B

Pathways from BioSystems

Homologies

Homo sapiens (human)	GAGE12J	NP_001091876.1
Homo sapiens (human)	GAGE12I	NP_001468.1
Homo sapiens (human)	GAGE12E	NP_001091888.1
Homo sapiens (human)	GAGE12D	NP_001120671.1
Homo sapiens (human)	GAGE2C	NP_001463.1
Homo sapiens (human)	GAGE12H	NP_001091880.1
Homo sapiens (human)	GAGE1	NP_001035753.1
Homo sapiens (human)	GAGE12G	NP_001091879.1
Homo sapiens (human)	GAGE12C	NP_001091878.1
Homo sapiens (human)	GAGE2A	NP_001120684.1
Homo sapiens (human)	GAGE2E	NP_001120672.1

Gene Ontology
Bibliography

Related articles in PubMed

Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.
Sun F, Chan E, Wu Z, Yang X, Marquez VE, Yu Q
Molecular cancer therapeutics8(12)3191-202(2009 Dec)

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.
Van den Eynde B, Peeters O, De Backer O, Gaugler B, Lucas S, Boon T
The Journal of experimental medicine182(3)689-98(1995 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that EZH2 is a crucial regulator of GAGE2 expression.
Title: Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.

The following GAGE2A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GAGE2A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu26508	NM_001127212.1 Latest version!	Homo sapiens G antigen 2A (GAGE2A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GAGE2A ( NM_001127212.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001120684.1 Homo sapiens G antigen 2A (GAGE2A), mRNA.

Price & Availability↑

CloneID	OHu26508
Clone ID Related Accession (Same CDS sequence)	NM_001127212.1
Accession Version	NM_001127212.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 351bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Homo sapiens(human)
Product	G antigen 2A/2B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EC558573.1, BC069397.1 and BG184057.1. On May 9, 2008 this sequence version replaced XM_001130991.2. ##Evidence-Data-START## Transcript exon combination :: BG700165.1, CF995383.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAGTTGGC GAGGAAGATC GACCTATCGG CCTAGACCAA GACGCTACGT AGAGCCTCCT 
GAAATGATTG GGCCTATGCG GCCCGAGCAG TTCAGTGATG AAGTGGAACC AGCAACACCT 
GAAGAAGGGG AACCAGCAAC TCAACGTCAG GATCCTGCAG CTGCTCAGGA GGGACAGGAT 
GAGGGAGCAT CTGCAGGTCA AGGGCCGAAG CCTGAAGCTC ATAGCCAGGA ACAGGGTCAC 
CCACAGACTG GGTGTGAGTG TGAAGATGGT CCTGATGGGC AGGAGATGGA CCCGCCAAAT 
CCAGAGGAGG TGAAAACGCC TGAAGAAGGT GAAAAGCAAT CACAGTGTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001120684.1
CDS	98..448
Translation	MSWRGRSTYRPRPRRYVEPPEMIGPMRPEQFSDEVEPATPEEGEPATQRQDPAAAQEGQDEGASAGQGPKPEAHSQEQGHPQTGCECEDGPDGQEMDPPNPEEVKTPEEGEKQSQC

Target ORF information:

RefSeq Version	NM_001127212.1
Organism	Homo sapiens(human)
Definition	Homo sapiens G antigen 2A (GAGE2A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127212.1

ORF Insert Sequence:

ATGAGTTGGC GAGGAAGATC GACCTATCGG CCTAGACCAA GACGCTACGT AGAGCCTCCT 
GAAATGATTG GGCCTATGCG GCCCGAGCAG TTCAGTGATG AAGTGGAACC AGCAACACCT 
GAAGAAGGGG AACCAGCAAC TCAACGTCAG GATCCTGCAG CTGCTCAGGA GGGACAGGAT 
GAGGGAGCAT CTGCAGGTCA AGGGCCGAAG CCTGAAGCTC ATAGCCAGGA ACAGGGTCAC 
CCACAGACTG GGTGTGAGTG TGAAGATGGT CCTGATGGGC AGGAGATGGA CCCGCCAAAT 
CCAGAGGAGG TGAAAACGCC TGAAGAAGGT GAAAAGCAAT CACAGTGTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.
Molecular cancer therapeutics8(12)3191-202(2009 Dec)
Sun F,Chan E,Wu Z,Yang X,Marquez VE,Yu Q

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.
The Journal of experimental medicine182(3)689-98(1995 Sep)
Van den Eynde B,Peeters O,De Backer O,Gaugler B,Lucas S,Boon T