CEND1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CEND1
Entrez Gene ID	51286
Full Name	cell cycle exit and neuronal differentiation 1
Synonyms	BM88
General protein information	Preferred Names cell cycle exit and neuronal differentiation 1 Names cell cycle exit and neuronal differentiation protein 1 BM88 antigen
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.5
Summary	The protein encoded by this gene is a neuron-specific protein. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have been reported for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	608213

mRNA and Protein(s)

mRNA	Protein	Name
NM_016564.4	NP_057648.2	cell cycle exit and neuronal differentiation protein 1
NM_016564.3	NP_057648.2	cell cycle exit and neuronal differentiation protein 1

Pathways from BioSystems

Homologies

	CEND1	XP_002799478.1
Mus musculus (house mouse)	Cend1	NP_067291.1
Homo sapiens (human)	CEND1	NP_057648.2
Pan troglodytes (chimpanzee)	CEND1	XP_001150340.2

Gene Ontology
Bibliography

Related articles in PubMed

BM88/Cend1 expression levels are critical for proliferation and differentiation of subventricular zone-derived neural precursor cells.
Katsimpardi L, Gaitanou M, Malnou CE, Lledo PM, Charneau P, Matsas R, Thomaidou D
Stem cells (Dayton, Ohio)26(7)1796-807(2008 Jul)

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Lim J, Hao T, Shaw C, Patel AJ, Szab? G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barab?si AL, Vidal M, Zoghbi HY
Cell125(4)801-14(2006 May)

Characterization of the BM88 promoter and identification of an 88 bp fragment sufficient to drive neurone-specific expression.
Papadodima O, Sergaki M, Hurel C, Mamalaki A, Matsas R
Journal of neurochemistry95(1)146-59(2005 Oct)

Cloning, expression and localization of human BM88 shows that it maps to chromosome 11p15.5, a region implicated in Beckwith-Wiedemann syndrome and tumorigenesis.
Gaitanou M, Buanne P, Pappa C, Georgopoulou N, Mamalaki A, Tirone F, Matsas R
The Biochemical journal355(Pt 3)715-24(2001 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

BM88/Cend1 participates in cell cycle control and neuronal differentiation mechanisms during neonatal SVZ neurogenesis and becomes crucial for the transition from neuroblasts to mature neurons when reaching high levels
Title: BM88/Cend1 expression levels are critical for proliferation and differentiation of subventricular zone-derived neural precursor cells.

The following CEND1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CEND1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30215	NM_016564.4 Latest version!	Homo sapiens cell cycle exit and neuronal differentiation 1 (CEND1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	Quote Price
View Old Accession Versions >>
OHu30215	NM_016564.3	Homo sapiens cell cycle exit and neuronal differentiation 1 (CEND1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	Quote Price
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CEND1 ( NM_016564.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057648.2 Homo sapiens cell cycle exit and neuronal differentiation 1 (CEND1), mRNA.

Price & Availability↑

CloneID	OHu30215
Clone ID Related Accession (Same CDS sequence)	NM_016564.4 , NM_016564.3
Accession Version	NM_016564.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	cell cycle exit and neuronal differentiation protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA066200.1 and AP006621.1. On Nov 22, 2018 this sequence version replaced NM_016564.3. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.171475.1, SRR3476690.390060.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000330106.5/ ENSP00000328336.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGTCCA GAGGGAAGTC AGCCAGCAGC CCCAAGCCCG ACACCAAGGT GCCCCAGGTC 
ACCACCGAGG CCAAGGTACC CCCGGCAGCC GATGGGAAAG CCCCCTTGAC CAAGCCCTCG 
AAGAAGGAGG CCCCGGCCGA GAAGCAGCAG CCGCCAGCAG CCCCCACCAC GGCACCTGCC 
AAGAAGACCT CGGCCAAGGC CGACCCTGCC CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCCCCCACGG TCCCCAGCAG TCCCGATGCA ACCCCGGAGC CCAAGGGTCC TGGGGACGGG 
GCGGAGGAAG ATGAGGCTGC CAGTGGGGGG CCTGGGGGCC GAGGTCCCTG GTCCTGTGAG 
AACTTCAACC CCCTGCTGGT GGCTGGGGGT GTGGCCGTGG CAGCCATAGC CCTGATTCTC 
GGTGTGGCCT TCCTGGTCCG GAAAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057648.2
CDS	144..593
Translation	MESRGKSASSPKPDTKVPQVTTEAKVPPAADGKAPLTKPSKKEAPAEKQQPPAAPTTAPAKKTSAKADPALLNNHSNLKPAPTVPSSPDATPEPKGPGDGAEEDEAASGGPGGRGPWSCENFNPLLVAGGVAVAAIALILGVAFLVRKK

Target ORF information:

RefSeq Version	NM_016564.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cell cycle exit and neuronal differentiation 1 (CEND1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016564.4

ORF Insert Sequence:

ATGGAGTCCA GAGGGAAGTC AGCCAGCAGC CCCAAGCCCG ACACCAAGGT GCCCCAGGTC 
ACCACCGAGG CCAAGGTACC CCCGGCAGCC GATGGGAAAG CCCCCTTGAC CAAGCCCTCG 
AAGAAGGAGG CCCCGGCCGA GAAGCAGCAG CCGCCAGCAG CCCCCACCAC GGCACCTGCC 
AAGAAGACCT CGGCCAAGGC CGACCCTGCC CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCCCCCACGG TCCCCAGCAG TCCCGATGCA ACCCCGGAGC CCAAGGGTCC TGGGGACGGG 
GCGGAGGAAG ATGAGGCTGC CAGTGGGGGG CCTGGGGGCC GAGGTCCCTG GTCCTGTGAG 
AACTTCAACC CCCTGCTGGT GGCTGGGGGT GTGGCCGTGG CAGCCATAGC CCTGATTCTC 
GGTGTGGCCT TCCTGGTCCG GAAAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CEND1 ( NM_016564.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057648.2 Homo sapiens cell cycle exit and neuronal differentiation 1 (CEND1), mRNA.

Price & Availability↑

CloneID	OHu30215
Clone ID Related Accession (Same CDS sequence)	NM_016564.4 , NM_016564.3
Accession Version	NM_016564.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	cell cycle exit and neuronal differentiation protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA066200.1 and AP006621.1. On Jun 23, 2006 this sequence version replaced NM_016564.2. ##Evidence-Data-START## Transcript exon combination :: BP309160.1, AK074547.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGAGTCCA GAGGGAAGTC AGCCAGCAGC CCCAAGCCCG ACACCAAGGT GCCCCAGGTC 
ACCACCGAGG CCAAGGTACC CCCGGCAGCC GATGGGAAAG CCCCCTTGAC CAAGCCCTCG 
AAGAAGGAGG CCCCGGCCGA GAAGCAGCAG CCGCCAGCAG CCCCCACCAC GGCACCTGCC 
AAGAAGACCT CGGCCAAGGC CGACCCTGCC CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCCCCCACGG TCCCCAGCAG TCCCGATGCA ACCCCGGAGC CCAAGGGTCC TGGGGACGGG 
GCGGAGGAAG ATGAGGCTGC CAGTGGGGGG CCTGGGGGCC GAGGTCCCTG GTCCTGTGAG 
AACTTCAACC CCCTGCTGGT GGCTGGGGGT GTGGCCGTGG CAGCCATAGC CCTGATTCTC 
GGTGTGGCCT TCCTGGTCCG GAAAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057648.2
CDS	180..629
Translation	MESRGKSASSPKPDTKVPQVTTEAKVPPAADGKAPLTKPSKKEAPAEKQQPPAAPTTAPAKKTSAKADPALLNNHSNLKPAPTVPSSPDATPEPKGPGDGAEEDEAASGGPGGRGPWSCENFNPLLVAGGVAVAAIALILGVAFLVRKK

Target ORF information:

RefSeq Version	NM_016564.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cell cycle exit and neuronal differentiation 1 (CEND1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016564.3

ORF Insert Sequence:

ATGGAGTCCA GAGGGAAGTC AGCCAGCAGC CCCAAGCCCG ACACCAAGGT GCCCCAGGTC 
ACCACCGAGG CCAAGGTACC CCCGGCAGCC GATGGGAAAG CCCCCTTGAC CAAGCCCTCG 
AAGAAGGAGG CCCCGGCCGA GAAGCAGCAG CCGCCAGCAG CCCCCACCAC GGCACCTGCC 
AAGAAGACCT CGGCCAAGGC CGACCCTGCC CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCCCCCACGG TCCCCAGCAG TCCCGATGCA ACCCCGGAGC CCAAGGGTCC TGGGGACGGG 
GCGGAGGAAG ATGAGGCTGC CAGTGGGGGG CCTGGGGGCC GAGGTCCCTG GTCCTGTGAG 
AACTTCAACC CCCTGCTGGT GGCTGGGGGT GTGGCCGTGG CAGCCATAGC CCTGATTCTC 
GGTGTGGCCT TCCTGGTCCG GAAAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

BM88/Cend1 expression levels are critical for proliferation and differentiation of subventricular zone-derived neural precursor cells.
Stem cells (Dayton, Ohio)26(7)1796-807(2008 Jul)
Katsimpardi L,Gaitanou M,Malnou CE,Lledo PM,Charneau P,Matsas R,Thomaidou D

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Cell125(4)801-14(2006 May)
Lim J,Hao T,Shaw C,Patel AJ,Szab? G,Rual JF,Fisk CJ,Li N,Smolyar A,Hill DE,Barab?si AL,Vidal M,Zoghbi HY

Characterization of the BM88 promoter and identification of an 88 bp fragment sufficient to drive neurone-specific expression.
Journal of neurochemistry95(1)146-59(2005 Oct)
Papadodima O,Sergaki M,Hurel C,Mamalaki A,Matsas R

Cloning, expression and localization of human BM88 shows that it maps to chromosome 11p15.5, a region implicated in Beckwith-Wiedemann syndrome and tumorigenesis.
The Biochemical journal355(Pt 3)715-24(2001 May)
Gaitanou M,Buanne P,Pappa C,Georgopoulou N,Mamalaki A,Tirone F,Matsas R