PDE11A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PDE11A
Entrez Gene ID	50940
Full Name	phosphodiesterase 11A
Synonyms	PPNAD2
General protein information	Preferred Names phosphodiesterase 11A Names dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A cAMP and cGMP cyclic nucleotide phosphodiesterase 11A
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q31.2
Summary	The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	604961
Disorder Html:	Pigmented nodular adrenocortical disease, primary, 2, 610475 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_016953.3	NP_058649.3	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 4
NM_001077196.1	NP_001070664.1	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 1
NM_001077358.1	NP_001070826.1	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 2
NM_001077197.1	NP_001070665.1	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 3
NM_016953.4	NP_058649.3	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 4
NM_001077196.2	NP_001070664.1	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PDE11A	XP_005640467.1
	PDE11A	XP_001097592.1
Danio rerio (zebrafish)	pde11a	XP_689838.4
Drosophila melanogaster (fruit fly)	Pde6	NP_650369.3
Homo sapiens (human)	PDE11A	NP_058649.3
Gallus gallus (chicken)	PDE11A	XP_421985.4
Bos taurus (cattle)	PDE11A	NP_001192351.1
Mus musculus (house mouse)	Pde11a	NP_001074502.1
Rattus norvegicus (Norway rat)	Pde11a	NP_543169.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004119	XP_312997.5
Xenopus tropicalis (tropical clawed frog)	pde11a	XP_002934646.1

Gene Ontology
Bibliography

Related articles in PubMed

A stop-codon of the phosphodiesterase 11A gene is associated with elevated blood pressure and measures of obesity.
Ohlsson T, Lindgren A, Engstr?m G, Jern C, Melander O
Journal of hypertension34(3)445-51; discussion 451(2016 Mar)

Rare inactivating PDE11A variants associated with testicular germ cell tumors.
Pathak A, Stewart DR, Faucz FR, Xekouki P, Bass S, Vogt A, Zhang X, Boland J, Yeager M, Loud JT, Nathanson KL, McGlynn KA, Stratakis CA, Greene MH, Mirabello L
Endocrine-related cancer22(6)909-17(2015 Dec)

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segr? AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, van der Harst P, Hayward C, den Heijer M, Igl W, Jackson AU, Kutalik Z, Luan J, Kemp JP, Kristiansson K, Ladenvall C, Lorentzon M, Montasser ME, Njajou OT, O'Reilly PF, Padmanabhan S, St Pourcain B, Rankinen T, Salo P, Tanaka T, Timpson NJ, Vitart V, Waite L, Wheeler W, Zhang W, Draisma HH, Feitosa MF, Kerr KF, Lind PA, Mihailov E, Onland-Moret NC, Song C, Weedon MN, Xie W, Yengo L, Absher D, Albert CM, Alonso A, Arking DE, de Bakker PI, Balkau B, Barlassina C, Benaglio P, Bis JC, Bouatia-Naji N, Brage S, Chanock SJ, Chines PS, Chung M, Darbar D, Dina C, D?rr M, Elliott P, Felix SB, Fischer K, Fuchsberger C, de Geus EJ, Goyette P, Gudnason V, Harris TB, Hartikainen AL, Havulinna AS, Heckbert SR, Hicks AA, Hofman A, Holewijn S, Hoogstra-Berends F, Hottenga JJ, Jensen MK, Johansson A, Junttila J, K??b S, Kanon B, Ketkar S, Khaw KT, Knowles JW, Kooner AS, Kors JA, Kumari M, Milani L, Laiho P, Lakatta EG, Langenberg C, Leusink M, Liu Y, Luben RN, Lunetta KL, Lynch SN, Markus MR, Marques-Vidal P, Mateo Leach I, McArdle WL, McCarroll SA, Medland SE, Miller KA, Montgomery GW, Morrison AC, M?ller-Nurasyid M, Navarro P, Nelis M, O'Connell JR, O'Donnell CJ, Ong KK, Newman AB, Peters A, Polasek O, Pouta A, Pramstaller PP, Psaty BM, Rao DC, Ring SM, Rossin EJ, Rudan D, Sanna S, Scott RA, Sehmi JS, Sharp S, Shin JT, Singleton AB, Smith AV, Soranzo N, Spector TD, Stewart C, Stringham HM, Tarasov KV, Uitterlinden AG, Vandenput L, Hwang SJ, Whitfield JB, Wijmenga C, Wild SH, Willemsen G, Wilson JF, Witteman JC, Wong A, Wong Q, Jamshidi Y, Zitting P, Boer JM, Boomsma DI, Borecki IB, van Duijn CM, Ekelund U, Forouhi NG, Froguel P, Hingorani A, Ingelsson E, Kivimaki M, Kronmal RA, Kuh D, Lind L, Martin NG, Oostra BA, Pedersen NL, Quertermous T, Rotter JI, van der Schouw YT, Verschuren WM, Walker M, Albanes D, Arnar DO, Assimes TL, Bandinelli S, Boehnke M, de Boer RA, Bouchard C, Caulfield WL, Chambers JC, Curhan G, Cusi D, Eriksson J, Ferrucci L, van Gilst WH, Glorioso N, de Graaf J, Groop L, Gyllensten U, Hsueh WC, Hu FB, Huikuri HV, Hunter DJ, Iribarren C, Isomaa B, Jarvelin MR, Jula A, K?h?nen M, Kiemeney LA, van der Klauw MM, Kooner JS, Kraft P, Iacoviello L, Lehtim?ki T, Lokki ML, Mitchell BD, Navis G, Nieminen MS, Ohlsson C, Poulter NR, Qi L, Raitakari OT, Rimm EB, Rioux JD, Rizzi F, Rudan I, Salomaa V, Sever PS, Shields DC, Shuldiner AR, Sinisalo J, Stanton AV, Stolk RP, Strachan DP, Tardif JC, Thorsteinsdottir U, Tuomilehto J, van Veldhuisen DJ, Virtamo J, Viikari J, Vollenweider P, Waeber G, Widen E, Cho YS, Olsen JV, Visscher PM, Willer C, Franke L, , , Erdmann J, Thompson JR, , Pfeufer A, , Sotoodehnia N, , Newton-Cheh C, , Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ
Nature genetics45(6)621-31(2013 Jun)

Phosphodiesterase 11A (PDE11A) gene defects in patients with acth-independent macronodular adrenal hyperplasia (AIMAH): functional variants may contribute to genetic susceptibility of bilateral adrenal tumors.
Vezzosi D, Lib? R, Baudry C, Rizk-Rabin M, Horvath A, Levy I, Ren?-Corail F, Ragazzon B, Stratakis CA, Vandecasteele G, Bertherat J
The Journal of clinical endocrinology and metabolism97(11)E2063-9(2012 Nov)

Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5).
?ckert S, Oelke M, Albrecht K, Breitmeier D, Kuczyk MA, Hedlund P
International journal of impotence research23(5)206-12(2011 Sep-Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

One percent of the Swedish population carries a PDE11A loss-of-function mutation which is associated with elevated BP, abdominal obesity, and risk of ischemic stroke.
Title: A stop-codon of the phosphodiesterase 11A gene is associated with elevated blood pressure and measures of obesity.

Testicular germ cell tumors had 55 PDE11A variants: 20 missense (10 new, 9 in transcript variant 4, 1 in transcript variant 3), 4 splice-site, 2 nonsense, 7 synonymous, and 22 intronic. p.F258Y, p.G291R, p.V820M, p.R545X, and p.K568R were only in cases.
Title: Rare inactivating PDE11A variants associated with testicular germ cell tumors.

PDE11A genetic variants may increase predisposition to ACTH-independent macronodular adrenal hyperplasia.
Title: Phosphodiesterase 11A (PDE11A) gene defects in patients with acth-independent macronodular adrenal hyperplasia (AIMAH): functional variants may contribute to genetic susceptibility of bilateral adrenal tumors.

found in single nerve trunks in the clitoral stroma
Title: Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5).

We demonstrate, in a large cohort of Carney Complex patients, a high frequency of PDE11A variants, suggesting that PDE11A is a genetic modifying factor for the development of testicular and adrenal tumors in patients with germline PRKAR1A mutation.
Title: Frequent phosphodiesterase 11A gene (PDE11A) defects in patients with Carney complex (CNC) caused by PRKAR1A mutations: PDE11A may contribute to adrenal and testicular tumors in CNC as a modifier of the phenotype.

The following PDE11A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PDE11A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16523	NM_016953.4 Latest version!	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu16456	NM_001077358.1 Latest version!	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu16579	NM_001077196.2 Latest version!	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu18294	NM_001077197.1 Latest version!	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu16523	NM_016953.3	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu16579	NM_001077196.1	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PDE11A ( NM_016953.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_058649.3 Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu16523
Clone ID Related Accession (Same CDS sequence)	NM_016953.3 , NM_016953.4
Accession Version	NM_016953.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2802bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB036704.1, AC011998.8, BC112393.1, AC073834.6 and AI919276.1. On Oct 24, 2006 this sequence version replaced NM_016953.2. Transcript Variant: This variant (4) represents the longest transcript and encodes the longest isoform (4). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB036704.1, BC112393.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCAGCCT CCCGCCTGGA CTTTGGGGAG GTGGAAACTT TCCTGGACAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGGAAGGGG AAGCAGGAGA TGGTTGAAAA GTGGCTGCAG 
AGGCACAGTC AGGGTCAGGG GGCTTTAGGT CCAAGGCCCT CTTTGGCTGG TACCAGCAGC 
TTGGCTCACA GCACCTGCAG AGGTGGCAGC AGCGTTGGTG GTGGCACTGG ACCAAATGGC 
TCTGCCCACA GCCAGCCCCT TCCCGGTGGC GGGGACTGTG GTGGGGTTCC CTTGAGTCCC 
AGCTGGGCCG GTGGCAGCAG GGGCGATGGG AACCTGCAGC GGAGAGCTTC TCAGAAAGAG 
CTAAGGAAGA GTTTTGCCCG CTCCAAGGCC ATCCACGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCTCAGGA ACCCCTGAGT AGTGTACGAC GGAGGGCACT TCTCCGGAAG 
GCAAGCTCCC TGCCCCCCAC CACAGCCCAT ATTCTCAGTG CGCTGCTGGA ATCGAGAGTG 
AATCTGCCTC GGTATCCCCC TACAGCCATC GACTACAAGT GCCATCTGAA AAAGCATAAT 
GAGCGTCAGT TCTTTCTGGA ATTGGTCAAA GATATCTCCA ATGACCTTGA CCTCACCAGC 
CTGAGCTACA AGATTCTCAT CTTTGTCTGC CTTATGGTGG ATGCTGACCG CTGCTCTCTT 
TTCCTGGTGG AAGGGGCAGC TGCTGGCAAG AAGACCTTGG TCTCCAAATT CTTTGATGTG 
CATGCAGGAA CACCTCTGCT GCCTTGCAGC AGCACAGAGA ACTCAAATGA GGTGCAGGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAGCATG GAGAAACGGT CAACATTCCT 
GATGCCTACC AGGATCGACG ATTCAATGAT GAAATCGACA AGCTAACTGG ATACAAGACA 
AAATCATTAT TGTGCATGCC TATCCGAAGC AGTGATGGTG AGATTATTGG TGTGGCCCAA 
GCGATAAATA AGATTCCTGA AGGAGCTCCA TTTACTGAAG ATGATGAAAA AGTTATGCAG 
ATGTATCTTC CATTTTGTGG AATCGCCATA TCTAACGCTC AGCTCTTTGC TGCCTCAAGG 
AAAGAATATG AAAGAAGCAG AGCTTTGCTA GAGGTGGTTA ATGACCTCTT TGAAGAACAG 
ACTGACCTGG AGAAAATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CTGTTTTACT CCTAGAGGAC ATCGAATCAC CAGTGGTGAA ATTTACCAAA 
TCCTTTGAAT TGATGTCCCC AAAGTGCAGT GCTGATGCTG AGAACAGTTT CAAAGAAAGC 
ATGGAGAAAT CATCATACTC CGACTGGCTA ATAAATAACA GCATTGCTGA GCTGGTTGCT 
TCAACAGGCC TTCCAGTGAA CATCAGTGAT GCCTACCAGG ATCCGCGCTT TGATGCAGAG 
GCAGACCAGA TATCTGGTTT TCACATAAGA TCTGTTCTTT GTGTCCCTAT TTGGAATAGC 
AACCACCAAA TAATTGGAGT GGCTCAAGTG TTAAACAGAC TTGATGGGAA ACCTTTTGAT 
GATGCAGATC AACGACTTTT TGAGGCTTTT GTCATCTTTT GTGGACTTGG CATCAACAAC 
ACAATTATGT ATGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC TCTTGATGTG 
CTATCATACC ATGCAACATG TTCAAAAGCT GAAGTTGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CAGAACTTGC CATCGATGAC ATTCATTTTG ATGACTTTTC TCTCGACGTT 
GATGCCATGA TCACAGCTGC TCTCCGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATTGACT ATGAGACACT GTGTAGGTGG CTTTTGACAG TGAGGAAAAA CTATCGGATG 
GTTCTATACC ACAACTGGAG ACATGCCTTC AACGTGTGTC AGCTGATGTT CGCGATGTTA 
ACCACTGCTG GGTTTCAAGA CATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGGC 
TCTGCCCTGG CCCAACTCTA TGGAACCTCT GCTACCTTGG AGCATCACCA TTTCAACCAC 
GCCGTGATGA TCCTTCAAAG TGAGGGTCAC AATATCTTTG CTAACCTGTC CTCCAAGGAA 
TATAGTGACC TTATGCAGCT TTTGAAGCAG TCAATATTGG CAACAGACCT CACGCTGTAC 
TTTGAGAGGA GAACTGAATT CTTTGAACTT GTCAGTAAAG GAGAATACGA TTGGAACATC 
AAAAACCATC GTGATATATT TCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCAGAACTTG TAACCAGTGA GTTCTTCGAA 
CAAGGAGATC GGGAGAGATT AGAGCTCAAA CTCACTCCTT CAGCAATTTT TGATCGGAAC 
CGGAAGGATG AACTGCCTCG GTTGCAACTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGGCAC TGGTGAAGGT CAACGTGAAA CTGAAGCCGA TGCTAGATTC AGTAGCTACA 
AACAGAAGTA AGTGGGAAGA GCTACACCAA AAACGACTGC TGGCCTCAAC TGCCTCATCC 
TCCCCTGCCA GTGTTATGGT AGCCAAGGAA GACAGGAACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058649.3
CDS	319..3120
Translation	MAASRLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSQGQGALGPRPSLAGTSSLAHSTCRGGSSVGGGTGPNGSAHSQPLPGGGDCGGVPLSPSWAGGSRGDGNLQRRASQKELRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPRYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPASVMVAKEDRN

Target ORF information:

RefSeq Version	NM_016953.3
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016953.3

ORF Insert Sequence:

ATGGCAGCCT CCCGCCTGGA CTTTGGGGAG GTGGAAACTT TCCTGGACAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGGAAGGGG AAGCAGGAGA TGGTTGAAAA GTGGCTGCAG 
AGGCACAGTC AGGGTCAGGG GGCTTTAGGT CCAAGGCCCT CTTTGGCTGG TACCAGCAGC 
TTGGCTCACA GCACCTGCAG AGGTGGCAGC AGCGTTGGTG GTGGCACTGG ACCAAATGGC 
TCTGCCCACA GCCAGCCCCT TCCCGGTGGC GGGGACTGTG GTGGGGTTCC CTTGAGTCCC 
AGCTGGGCCG GTGGCAGCAG GGGCGATGGG AACCTGCAGC GGAGAGCTTC TCAGAAAGAG 
CTAAGGAAGA GTTTTGCCCG CTCCAAGGCC ATCCACGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCTCAGGA ACCCCTGAGT AGTGTACGAC GGAGGGCACT TCTCCGGAAG 
GCAAGCTCCC TGCCCCCCAC CACAGCCCAT ATTCTCAGTG CGCTGCTGGA ATCGAGAGTG 
AATCTGCCTC GGTATCCCCC TACAGCCATC GACTACAAGT GCCATCTGAA AAAGCATAAT 
GAGCGTCAGT TCTTTCTGGA ATTGGTCAAA GATATCTCCA ATGACCTTGA CCTCACCAGC 
CTGAGCTACA AGATTCTCAT CTTTGTCTGC CTTATGGTGG ATGCTGACCG CTGCTCTCTT 
TTCCTGGTGG AAGGGGCAGC TGCTGGCAAG AAGACCTTGG TCTCCAAATT CTTTGATGTG 
CATGCAGGAA CACCTCTGCT GCCTTGCAGC AGCACAGAGA ACTCAAATGA GGTGCAGGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAGCATG GAGAAACGGT CAACATTCCT 
GATGCCTACC AGGATCGACG ATTCAATGAT GAAATCGACA AGCTAACTGG ATACAAGACA 
AAATCATTAT TGTGCATGCC TATCCGAAGC AGTGATGGTG AGATTATTGG TGTGGCCCAA 
GCGATAAATA AGATTCCTGA AGGAGCTCCA TTTACTGAAG ATGATGAAAA AGTTATGCAG 
ATGTATCTTC CATTTTGTGG AATCGCCATA TCTAACGCTC AGCTCTTTGC TGCCTCAAGG 
AAAGAATATG AAAGAAGCAG AGCTTTGCTA GAGGTGGTTA ATGACCTCTT TGAAGAACAG 
ACTGACCTGG AGAAAATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CTGTTTTACT CCTAGAGGAC ATCGAATCAC CAGTGGTGAA ATTTACCAAA 
TCCTTTGAAT TGATGTCCCC AAAGTGCAGT GCTGATGCTG AGAACAGTTT CAAAGAAAGC 
ATGGAGAAAT CATCATACTC CGACTGGCTA ATAAATAACA GCATTGCTGA GCTGGTTGCT 
TCAACAGGCC TTCCAGTGAA CATCAGTGAT GCCTACCAGG ATCCGCGCTT TGATGCAGAG 
GCAGACCAGA TATCTGGTTT TCACATAAGA TCTGTTCTTT GTGTCCCTAT TTGGAATAGC 
AACCACCAAA TAATTGGAGT GGCTCAAGTG TTAAACAGAC TTGATGGGAA ACCTTTTGAT 
GATGCAGATC AACGACTTTT TGAGGCTTTT GTCATCTTTT GTGGACTTGG CATCAACAAC 
ACAATTATGT ATGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC TCTTGATGTG 
CTATCATACC ATGCAACATG TTCAAAAGCT GAAGTTGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CAGAACTTGC CATCGATGAC ATTCATTTTG ATGACTTTTC TCTCGACGTT 
GATGCCATGA TCACAGCTGC TCTCCGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATTGACT ATGAGACACT GTGTAGGTGG CTTTTGACAG TGAGGAAAAA CTATCGGATG 
GTTCTATACC ACAACTGGAG ACATGCCTTC AACGTGTGTC AGCTGATGTT CGCGATGTTA 
ACCACTGCTG GGTTTCAAGA CATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGGC 
TCTGCCCTGG CCCAACTCTA TGGAACCTCT GCTACCTTGG AGCATCACCA TTTCAACCAC 
GCCGTGATGA TCCTTCAAAG TGAGGGTCAC AATATCTTTG CTAACCTGTC CTCCAAGGAA 
TATAGTGACC TTATGCAGCT TTTGAAGCAG TCAATATTGG CAACAGACCT CACGCTGTAC 
TTTGAGAGGA GAACTGAATT CTTTGAACTT GTCAGTAAAG GAGAATACGA TTGGAACATC 
AAAAACCATC GTGATATATT TCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCAGAACTTG TAACCAGTGA GTTCTTCGAA 
CAAGGAGATC GGGAGAGATT AGAGCTCAAA CTCACTCCTT CAGCAATTTT TGATCGGAAC 
CGGAAGGATG AACTGCCTCG GTTGCAACTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGGCAC TGGTGAAGGT CAACGTGAAA CTGAAGCCGA TGCTAGATTC AGTAGCTACA 
AACAGAAGTA AGTGGGAAGA GCTACACCAA AAACGACTGC TGGCCTCAAC TGCCTCATCC 
TCCCCTGCCA GTGTTATGGT AGCCAAGGAA GACAGGAACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDE11A ( NM_016953.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_058649.3 Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu16523
Clone ID Related Accession (Same CDS sequence)	NM_016953.3 , NM_016953.4
Accession Version	NM_016953.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2802bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC011998.8, AB036704.1, BC112393.1, AC073834.6 and AI919276.1. On Nov 22, 2018 this sequence version replaced NM_016953.3. Transcript Variant: This variant (4) represents the longest transcript and encodes the longest isoform (4). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB036704.1, BC112393.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000286063.11/ ENSP00000286063.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAGCCT CCCGCCTGGA CTTTGGGGAG GTGGAAACTT TCCTGGACAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGGAAGGGG AAGCAGGAGA TGGTTGAAAA GTGGCTGCAG 
AGGCACAGTC AGGGTCAGGG GGCTTTAGGT CCAAGGCCCT CTTTGGCTGG TACCAGCAGC 
TTGGCTCACA GCACCTGCAG AGGTGGCAGC AGCGTTGGTG GTGGCACTGG ACCAAATGGC 
TCTGCCCACA GCCAGCCCCT TCCCGGTGGC GGGGACTGTG GTGGGGTTCC CTTGAGTCCC 
AGCTGGGCCG GTGGCAGCAG GGGCGATGGG AACCTGCAGC GGAGAGCTTC TCAGAAAGAG 
CTAAGGAAGA GTTTTGCCCG CTCCAAGGCC ATCCACGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCTCAGGA ACCCCTGAGT AGTGTACGAC GGAGGGCACT TCTCCGGAAG 
GCAAGCTCCC TGCCCCCCAC CACAGCCCAT ATTCTCAGTG CGCTGCTGGA ATCGAGAGTG 
AATCTGCCTC GGTATCCCCC TACAGCCATC GACTACAAGT GCCATCTGAA AAAGCATAAT 
GAGCGTCAGT TCTTTCTGGA ATTGGTCAAA GATATCTCCA ATGACCTTGA CCTCACCAGC 
CTGAGCTACA AGATTCTCAT CTTTGTCTGC CTTATGGTGG ATGCTGACCG CTGCTCTCTT 
TTCCTGGTGG AAGGGGCAGC TGCTGGCAAG AAGACCTTGG TCTCCAAATT CTTTGATGTG 
CATGCAGGAA CACCTCTGCT GCCTTGCAGC AGCACAGAGA ACTCAAATGA GGTGCAGGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAGCATG GAGAAACGGT CAACATTCCT 
GATGCCTACC AGGATCGACG ATTCAATGAT GAAATCGACA AGCTAACTGG ATACAAGACA 
AAATCATTAT TGTGCATGCC TATCCGAAGC AGTGATGGTG AGATTATTGG TGTGGCCCAA 
GCGATAAATA AGATTCCTGA AGGAGCTCCA TTTACTGAAG ATGATGAAAA AGTTATGCAG 
ATGTATCTTC CATTTTGTGG AATCGCCATA TCTAACGCTC AGCTCTTTGC TGCCTCAAGG 
AAAGAATATG AAAGAAGCAG AGCTTTGCTA GAGGTGGTTA ATGACCTCTT TGAAGAACAG 
ACTGACCTGG AGAAAATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CTGTTTTACT CCTAGAGGAC ATCGAATCAC CAGTGGTGAA ATTTACCAAA 
TCCTTTGAAT TGATGTCCCC AAAGTGCAGT GCTGATGCTG AGAACAGTTT CAAAGAAAGC 
ATGGAGAAAT CATCATACTC CGACTGGCTA ATAAATAACA GCATTGCTGA GCTGGTTGCT 
TCAACAGGCC TTCCAGTGAA CATCAGTGAT GCCTACCAGG ATCCGCGCTT TGATGCAGAG 
GCAGACCAGA TATCTGGTTT TCACATAAGA TCTGTTCTTT GTGTCCCTAT TTGGAATAGC 
AACCACCAAA TAATTGGAGT GGCTCAAGTG TTAAACAGAC TTGATGGGAA ACCTTTTGAT 
GATGCAGATC AACGACTTTT TGAGGCTTTT GTCATCTTTT GTGGACTTGG CATCAACAAC 
ACAATTATGT ATGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC TCTTGATGTG 
CTATCATACC ATGCAACATG TTCAAAAGCT GAAGTTGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CAGAACTTGC CATCGATGAC ATTCATTTTG ATGACTTTTC TCTCGACGTT 
GATGCCATGA TCACAGCTGC TCTCCGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATTGACT ATGAGACACT GTGTAGGTGG CTTTTGACAG TGAGGAAAAA CTATCGGATG 
GTTCTATACC ACAACTGGAG ACATGCCTTC AACGTGTGTC AGCTGATGTT CGCGATGTTA 
ACCACTGCTG GGTTTCAAGA CATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGGC 
TCTGCCCTGG CCCAACTCTA TGGAACCTCT GCTACCTTGG AGCATCACCA TTTCAACCAC 
GCCGTGATGA TCCTTCAAAG TGAGGGTCAC AATATCTTTG CTAACCTGTC CTCCAAGGAA 
TATAGTGACC TTATGCAGCT TTTGAAGCAG TCAATATTGG CAACAGACCT CACGCTGTAC 
TTTGAGAGGA GAACTGAATT CTTTGAACTT GTCAGTAAAG GAGAATACGA TTGGAACATC 
AAAAACCATC GTGATATATT TCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCAGAACTTG TAACCAGTGA GTTCTTCGAA 
CAAGGAGATC GGGAGAGATT AGAGCTCAAA CTCACTCCTT CAGCAATTTT TGATCGGAAC 
CGGAAGGATG AACTGCCTCG GTTGCAACTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGGCAC TGGTGAAGGT CAACGTGAAA CTGAAGCCGA TGCTAGATTC AGTAGCTACA 
AACAGAAGTA AGTGGGAAGA GCTACACCAA AAACGACTGC TGGCCTCAAC TGCCTCATCC 
TCCCCTGCCA GTGTTATGGT AGCCAAGGAA GACAGGAACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058649.3
CDS	341..3142
Translation	MAASRLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSQGQGALGPRPSLAGTSSLAHSTCRGGSSVGGGTGPNGSAHSQPLPGGGDCGGVPLSPSWAGGSRGDGNLQRRASQKELRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPRYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPASVMVAKEDRN

Target ORF information:

RefSeq Version	NM_016953.4
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016953.4

ORF Insert Sequence:

ATGGCAGCCT CCCGCCTGGA CTTTGGGGAG GTGGAAACTT TCCTGGACAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGGAAGGGG AAGCAGGAGA TGGTTGAAAA GTGGCTGCAG 
AGGCACAGTC AGGGTCAGGG GGCTTTAGGT CCAAGGCCCT CTTTGGCTGG TACCAGCAGC 
TTGGCTCACA GCACCTGCAG AGGTGGCAGC AGCGTTGGTG GTGGCACTGG ACCAAATGGC 
TCTGCCCACA GCCAGCCCCT TCCCGGTGGC GGGGACTGTG GTGGGGTTCC CTTGAGTCCC 
AGCTGGGCCG GTGGCAGCAG GGGCGATGGG AACCTGCAGC GGAGAGCTTC TCAGAAAGAG 
CTAAGGAAGA GTTTTGCCCG CTCCAAGGCC ATCCACGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCTCAGGA ACCCCTGAGT AGTGTACGAC GGAGGGCACT TCTCCGGAAG 
GCAAGCTCCC TGCCCCCCAC CACAGCCCAT ATTCTCAGTG CGCTGCTGGA ATCGAGAGTG 
AATCTGCCTC GGTATCCCCC TACAGCCATC GACTACAAGT GCCATCTGAA AAAGCATAAT 
GAGCGTCAGT TCTTTCTGGA ATTGGTCAAA GATATCTCCA ATGACCTTGA CCTCACCAGC 
CTGAGCTACA AGATTCTCAT CTTTGTCTGC CTTATGGTGG ATGCTGACCG CTGCTCTCTT 
TTCCTGGTGG AAGGGGCAGC TGCTGGCAAG AAGACCTTGG TCTCCAAATT CTTTGATGTG 
CATGCAGGAA CACCTCTGCT GCCTTGCAGC AGCACAGAGA ACTCAAATGA GGTGCAGGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAGCATG GAGAAACGGT CAACATTCCT 
GATGCCTACC AGGATCGACG ATTCAATGAT GAAATCGACA AGCTAACTGG ATACAAGACA 
AAATCATTAT TGTGCATGCC TATCCGAAGC AGTGATGGTG AGATTATTGG TGTGGCCCAA 
GCGATAAATA AGATTCCTGA AGGAGCTCCA TTTACTGAAG ATGATGAAAA AGTTATGCAG 
ATGTATCTTC CATTTTGTGG AATCGCCATA TCTAACGCTC AGCTCTTTGC TGCCTCAAGG 
AAAGAATATG AAAGAAGCAG AGCTTTGCTA GAGGTGGTTA ATGACCTCTT TGAAGAACAG 
ACTGACCTGG AGAAAATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CTGTTTTACT CCTAGAGGAC ATCGAATCAC CAGTGGTGAA ATTTACCAAA 
TCCTTTGAAT TGATGTCCCC AAAGTGCAGT GCTGATGCTG AGAACAGTTT CAAAGAAAGC 
ATGGAGAAAT CATCATACTC CGACTGGCTA ATAAATAACA GCATTGCTGA GCTGGTTGCT 
TCAACAGGCC TTCCAGTGAA CATCAGTGAT GCCTACCAGG ATCCGCGCTT TGATGCAGAG 
GCAGACCAGA TATCTGGTTT TCACATAAGA TCTGTTCTTT GTGTCCCTAT TTGGAATAGC 
AACCACCAAA TAATTGGAGT GGCTCAAGTG TTAAACAGAC TTGATGGGAA ACCTTTTGAT 
GATGCAGATC AACGACTTTT TGAGGCTTTT GTCATCTTTT GTGGACTTGG CATCAACAAC 
ACAATTATGT ATGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC TCTTGATGTG 
CTATCATACC ATGCAACATG TTCAAAAGCT GAAGTTGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CAGAACTTGC CATCGATGAC ATTCATTTTG ATGACTTTTC TCTCGACGTT 
GATGCCATGA TCACAGCTGC TCTCCGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATTGACT ATGAGACACT GTGTAGGTGG CTTTTGACAG TGAGGAAAAA CTATCGGATG 
GTTCTATACC ACAACTGGAG ACATGCCTTC AACGTGTGTC AGCTGATGTT CGCGATGTTA 
ACCACTGCTG GGTTTCAAGA CATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGGC 
TCTGCCCTGG CCCAACTCTA TGGAACCTCT GCTACCTTGG AGCATCACCA TTTCAACCAC 
GCCGTGATGA TCCTTCAAAG TGAGGGTCAC AATATCTTTG CTAACCTGTC CTCCAAGGAA 
TATAGTGACC TTATGCAGCT TTTGAAGCAG TCAATATTGG CAACAGACCT CACGCTGTAC 
TTTGAGAGGA GAACTGAATT CTTTGAACTT GTCAGTAAAG GAGAATACGA TTGGAACATC 
AAAAACCATC GTGATATATT TCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCAGAACTTG TAACCAGTGA GTTCTTCGAA 
CAAGGAGATC GGGAGAGATT AGAGCTCAAA CTCACTCCTT CAGCAATTTT TGATCGGAAC 
CGGAAGGATG AACTGCCTCG GTTGCAACTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGGCAC TGGTGAAGGT CAACGTGAAA CTGAAGCCGA TGCTAGATTC AGTAGCTACA 
AACAGAAGTA AGTGGGAAGA GCTACACCAA AAACGACTGC TGGCCTCAAC TGCCTCATCC 
TCCCCTGCCA GTGTTATGGT AGCCAAGGAA GACAGGAACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDE11A ( NM_001077358.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001070826.1 Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16456
Clone ID Related Accession (Same CDS sequence)	NM_001077358.1
Accession Version	NM_001077358.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1728bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX105579.1, AF281865.1 and AC073834.6. Transcript Variant: This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 4. The resulting isoform (2) has a shorter N-terminus, compared to isoform 4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AF281865.1, HM771389.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END##

ATGCAGATGT ATCTTCCATT TTGTGGAATC GCCATATCTA ACGCTCAGCT CTTTGCTGCC 
TCAAGGAAAG AATATGAAAG AAGCAGAGCT TTGCTAGAGG TGGTTAATGA CCTCTTTGAA 
GAACAGACTG ACCTGGAGAA AATTGTCAAG AAAATAATGC ATCGGGCCCA AACTCTGCTG 
AAATGTGAAC GCTGTTCTGT TTTACTCCTA GAGGACATCG AATCACCAGT GGTGAAATTT 
ACCAAATCCT TTGAATTGAT GTCCCCAAAG TGCAGTGCTG ATGCTGAGAA CAGTTTCAAA 
GAAAGCATGG AGAAATCATC ATACTCCGAC TGGCTAATAA ATAACAGCAT TGCTGAGCTG 
GTTGCTTCAA CAGGCCTTCC AGTGAACATC AGTGATGCCT ACCAGGATCC GCGCTTTGAT 
GCAGAGGCAG ACCAGATATC TGGTTTTCAC ATAAGATCTG TTCTTTGTGT CCCTATTTGG 
AATAGCAACC ACCAAATAAT TGGAGTGGCT CAAGTGTTAA ACAGACTTGA TGGGAAACCT 
TTTGATGATG CAGATCAACG ACTTTTTGAG GCTTTTGTCA TCTTTTGTGG ACTTGGCATC 
AACAACACAA TTATGTATGA TCAAGTGAAG AAGTCCTGGG CCAAGCAGTC TGTGGCTCTT 
GATGTGCTAT CATACCATGC AACATGTTCA AAAGCTGAAG TTGACAAGTT TAAGGCAGCC 
AACATCCCTC TGGTGTCAGA ACTTGCCATC GATGACATTC ATTTTGATGA CTTTTCTCTC 
GACGTTGATG CCATGATCAC AGCTGCTCTC CGGATGTTCA TGGAGCTGGG GATGGTACAG 
AAATTTAAAA TTGACTATGA GACACTGTGT AGGTGGCTTT TGACAGTGAG GAAAAACTAT 
CGGATGGTTC TATACCACAA CTGGAGACAT GCCTTCAACG TGTGTCAGCT GATGTTCGCG 
ATGTTAACCA CTGCTGGGTT TCAAGACATT CTGACCGAGG TGGAAATTTT AGCGGTGATT 
GTGGGATGCC TGTGTCATGA CCTCGACCAC AGGGGAACCA ACAATGCCTT CCAAGCTAAG 
AGTGGCTCTG CCCTGGCCCA ACTCTATGGA ACCTCTGCTA CCTTGGAGCA TCACCATTTC 
AACCACGCCG TGATGATCCT TCAAAGTGAG GGTCACAATA TCTTTGCTAA CCTGTCCTCC 
AAGGAATATA GTGACCTTAT GCAGCTTTTG AAGCAGTCAA TATTGGCAAC AGACCTCACG 
CTGTACTTTG AGAGGAGAAC TGAATTCTTT GAACTTGTCA GTAAAGGAGA ATACGATTGG 
AACATCAAAA ACCATCGTGA TATATTTCGA TCAATGTTAA TGACAGCCTG TGACCTTGGA 
GCCGTGACCA AACCGTGGGA GATCTCCAGA CAGGTGGCAG AACTTGTAAC CAGTGAGTTC 
TTCGAACAAG GAGATCGGGA GAGATTAGAG CTCAAACTCA CTCCTTCAGC AATTTTTGAT 
CGGAACCGGA AGGATGAACT GCCTCGGTTG CAACTGGAGT GGATTGATAG CATCTGCATG 
CCTTTGTATC AGGCACTGGT GAAGGTCAAC GTGAAACTGA AGCCGATGCT AGATTCAGTA 
GCTACAAACA GAAGTAAGTG GGAAGAGCTA CACCAAAAAC GACTGCTGGC CTCAACTGCC 
TCATCCTCCC CTGCCAGTGT TATGGTAGCC AAGGAAGACA GGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070826.1
CDS	134..1861
Translation	MQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPASVMVAKEDRN

Target ORF information:

RefSeq Version	NM_001077358.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077358.1

ORF Insert Sequence:

ATGCAGATGT ATCTTCCATT TTGTGGAATC GCCATATCTA ACGCTCAGCT CTTTGCTGCC 
TCAAGGAAAG AATATGAAAG AAGCAGAGCT TTGCTAGAGG TGGTTAATGA CCTCTTTGAA 
GAACAGACTG ACCTGGAGAA AATTGTCAAG AAAATAATGC ATCGGGCCCA AACTCTGCTG 
AAATGTGAAC GCTGTTCTGT TTTACTCCTA GAGGACATCG AATCACCAGT GGTGAAATTT 
ACCAAATCCT TTGAATTGAT GTCCCCAAAG TGCAGTGCTG ATGCTGAGAA CAGTTTCAAA 
GAAAGCATGG AGAAATCATC ATACTCCGAC TGGCTAATAA ATAACAGCAT TGCTGAGCTG 
GTTGCTTCAA CAGGCCTTCC AGTGAACATC AGTGATGCCT ACCAGGATCC GCGCTTTGAT 
GCAGAGGCAG ACCAGATATC TGGTTTTCAC ATAAGATCTG TTCTTTGTGT CCCTATTTGG 
AATAGCAACC ACCAAATAAT TGGAGTGGCT CAAGTGTTAA ACAGACTTGA TGGGAAACCT 
TTTGATGATG CAGATCAACG ACTTTTTGAG GCTTTTGTCA TCTTTTGTGG ACTTGGCATC 
AACAACACAA TTATGTATGA TCAAGTGAAG AAGTCCTGGG CCAAGCAGTC TGTGGCTCTT 
GATGTGCTAT CATACCATGC AACATGTTCA AAAGCTGAAG TTGACAAGTT TAAGGCAGCC 
AACATCCCTC TGGTGTCAGA ACTTGCCATC GATGACATTC ATTTTGATGA CTTTTCTCTC 
GACGTTGATG CCATGATCAC AGCTGCTCTC CGGATGTTCA TGGAGCTGGG GATGGTACAG 
AAATTTAAAA TTGACTATGA GACACTGTGT AGGTGGCTTT TGACAGTGAG GAAAAACTAT 
CGGATGGTTC TATACCACAA CTGGAGACAT GCCTTCAACG TGTGTCAGCT GATGTTCGCG 
ATGTTAACCA CTGCTGGGTT TCAAGACATT CTGACCGAGG TGGAAATTTT AGCGGTGATT 
GTGGGATGCC TGTGTCATGA CCTCGACCAC AGGGGAACCA ACAATGCCTT CCAAGCTAAG 
AGTGGCTCTG CCCTGGCCCA ACTCTATGGA ACCTCTGCTA CCTTGGAGCA TCACCATTTC 
AACCACGCCG TGATGATCCT TCAAAGTGAG GGTCACAATA TCTTTGCTAA CCTGTCCTCC 
AAGGAATATA GTGACCTTAT GCAGCTTTTG AAGCAGTCAA TATTGGCAAC AGACCTCACG 
CTGTACTTTG AGAGGAGAAC TGAATTCTTT GAACTTGTCA GTAAAGGAGA ATACGATTGG 
AACATCAAAA ACCATCGTGA TATATTTCGA TCAATGTTAA TGACAGCCTG TGACCTTGGA 
GCCGTGACCA AACCGTGGGA GATCTCCAGA CAGGTGGCAG AACTTGTAAC CAGTGAGTTC 
TTCGAACAAG GAGATCGGGA GAGATTAGAG CTCAAACTCA CTCCTTCAGC AATTTTTGAT 
CGGAACCGGA AGGATGAACT GCCTCGGTTG CAACTGGAGT GGATTGATAG CATCTGCATG 
CCTTTGTATC AGGCACTGGT GAAGGTCAAC GTGAAACTGA AGCCGATGCT AGATTCAGTA 
GCTACAAACA GAAGTAAGTG GGAAGAGCTA CACCAAAAAC GACTGCTGGC CTCAACTGCC 
TCATCCTCCC CTGCCAGTGT TATGGTAGCC AAGGAAGACA GGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDE11A ( NM_001077196.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001070664.1 Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16579
Clone ID Related Accession (Same CDS sequence)	NM_001077196.1 , NM_001077196.2
Accession Version	NM_001077196.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073892.6, AJ251509.1, AC073834.6 and AI919276.1. Transcript Variant: This variant (1) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 4. The resulting isoform (1) has a shorter N-terminus, compared to isoform 4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ251509.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCCCCAA AGTGCAGTGC TGATGCTGAG AACAGTTTCA AAGAAAGCAT GGAGAAATCA 
TCATACTCCG ACTGGCTAAT AAATAACAGC ATTGCTGAGC TGGTTGCTTC AACAGGCCTT 
CCAGTGAACA TCAGTGATGC CTACCAGGAT CCGCGCTTTG ATGCAGAGGC AGACCAGATA 
TCTGGTTTTC ACATAAGATC TGTTCTTTGT GTCCCTATTT GGAATAGCAA CCACCAAATA 
ATTGGAGTGG CTCAAGTGTT AAACAGACTT GATGGGAAAC CTTTTGATGA TGCAGATCAA 
CGACTTTTTG AGGCTTTTGT CATCTTTTGT GGACTTGGCA TCAACAACAC AATTATGTAT 
GATCAAGTGA AGAAGTCCTG GGCCAAGCAG TCTGTGGCTC TTGATGTGCT ATCATACCAT 
GCAACATGTT CAAAAGCTGA AGTTGACAAG TTTAAGGCAG CCAACATCCC TCTGGTGTCA 
GAACTTGCCA TCGATGACAT TCATTTTGAT GACTTTTCTC TCGACGTTGA TGCCATGATC 
ACAGCTGCTC TCCGGATGTT CATGGAGCTG GGGATGGTAC AGAAATTTAA AATTGACTAT 
GAGACACTGT GTAGGTGGCT TTTGACAGTG AGGAAAAACT ATCGGATGGT TCTATACCAC 
AACTGGAGAC ATGCCTTCAA CGTGTGTCAG CTGATGTTCG CGATGTTAAC CACTGCTGGG 
TTTCAAGACA TTCTGACCGA GGTGGAAATT TTAGCGGTGA TTGTGGGATG CCTGTGTCAT 
GACCTCGACC ACAGGGGAAC CAACAATGCC TTCCAAGCTA AGAGTGGCTC TGCCCTGGCC 
CAACTCTATG GAACCTCTGC TACCTTGGAG CATCACCATT TCAACCACGC CGTGATGATC 
CTTCAAAGTG AGGGTCACAA TATCTTTGCT AACCTGTCCT CCAAGGAATA TAGTGACCTT 
ATGCAGCTTT TGAAGCAGTC AATATTGGCA ACAGACCTCA CGCTGTACTT TGAGAGGAGA 
ACTGAATTCT TTGAACTTGT CAGTAAAGGA GAATACGATT GGAACATCAA AAACCATCGT 
GATATATTTC GATCAATGTT AATGACAGCC TGTGACCTTG GAGCCGTGAC CAAACCGTGG 
GAGATCTCCA GACAGGTGGC AGAACTTGTA ACCAGTGAGT TCTTCGAACA AGGAGATCGG 
GAGAGATTAG AGCTCAAACT CACTCCTTCA GCAATTTTTG ATCGGAACCG GAAGGATGAA 
CTGCCTCGGT TGCAACTGGA GTGGATTGAT AGCATCTGCA TGCCTTTGTA TCAGGCACTG 
GTGAAGGTCA ACGTGAAACT GAAGCCGATG CTAGATTCAG TAGCTACAAA CAGAAGTAAG 
TGGGAAGAGC TACACCAAAA ACGACTGCTG GCCTCAACTG CCTCATCCTC CCCTGCCAGT 
GTTATGGTAG CCAAGGAAGA CAGGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070664.1
CDS	152..1621
Translation	MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPASVMVAKEDRN

Target ORF information:

RefSeq Version	NM_001077196.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077196.1

ORF Insert Sequence:

ATGTCCCCAA AGTGCAGTGC TGATGCTGAG AACAGTTTCA AAGAAAGCAT GGAGAAATCA 
TCATACTCCG ACTGGCTAAT AAATAACAGC ATTGCTGAGC TGGTTGCTTC AACAGGCCTT 
CCAGTGAACA TCAGTGATGC CTACCAGGAT CCGCGCTTTG ATGCAGAGGC AGACCAGATA 
TCTGGTTTTC ACATAAGATC TGTTCTTTGT GTCCCTATTT GGAATAGCAA CCACCAAATA 
ATTGGAGTGG CTCAAGTGTT AAACAGACTT GATGGGAAAC CTTTTGATGA TGCAGATCAA 
CGACTTTTTG AGGCTTTTGT CATCTTTTGT GGACTTGGCA TCAACAACAC AATTATGTAT 
GATCAAGTGA AGAAGTCCTG GGCCAAGCAG TCTGTGGCTC TTGATGTGCT ATCATACCAT 
GCAACATGTT CAAAAGCTGA AGTTGACAAG TTTAAGGCAG CCAACATCCC TCTGGTGTCA 
GAACTTGCCA TCGATGACAT TCATTTTGAT GACTTTTCTC TCGACGTTGA TGCCATGATC 
ACAGCTGCTC TCCGGATGTT CATGGAGCTG GGGATGGTAC AGAAATTTAA AATTGACTAT 
GAGACACTGT GTAGGTGGCT TTTGACAGTG AGGAAAAACT ATCGGATGGT TCTATACCAC 
AACTGGAGAC ATGCCTTCAA CGTGTGTCAG CTGATGTTCG CGATGTTAAC CACTGCTGGG 
TTTCAAGACA TTCTGACCGA GGTGGAAATT TTAGCGGTGA TTGTGGGATG CCTGTGTCAT 
GACCTCGACC ACAGGGGAAC CAACAATGCC TTCCAAGCTA AGAGTGGCTC TGCCCTGGCC 
CAACTCTATG GAACCTCTGC TACCTTGGAG CATCACCATT TCAACCACGC CGTGATGATC 
CTTCAAAGTG AGGGTCACAA TATCTTTGCT AACCTGTCCT CCAAGGAATA TAGTGACCTT 
ATGCAGCTTT TGAAGCAGTC AATATTGGCA ACAGACCTCA CGCTGTACTT TGAGAGGAGA 
ACTGAATTCT TTGAACTTGT CAGTAAAGGA GAATACGATT GGAACATCAA AAACCATCGT 
GATATATTTC GATCAATGTT AATGACAGCC TGTGACCTTG GAGCCGTGAC CAAACCGTGG 
GAGATCTCCA GACAGGTGGC AGAACTTGTA ACCAGTGAGT TCTTCGAACA AGGAGATCGG 
GAGAGATTAG AGCTCAAACT CACTCCTTCA GCAATTTTTG ATCGGAACCG GAAGGATGAA 
CTGCCTCGGT TGCAACTGGA GTGGATTGAT AGCATCTGCA TGCCTTTGTA TCAGGCACTG 
GTGAAGGTCA ACGTGAAACT GAAGCCGATG CTAGATTCAG TAGCTACAAA CAGAAGTAAG 
TGGGAAGAGC TACACCAAAA ACGACTGCTG GCCTCAACTG CCTCATCCTC CCCTGCCAGT 
GTTATGGTAG CCAAGGAAGA CAGGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDE11A ( NM_001077196.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001070664.1 Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16579
Clone ID Related Accession (Same CDS sequence)	NM_001077196.1 , NM_001077196.2
Accession Version	NM_001077196.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-06
Organism	Homo sapiens(human)
Product	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073892.6, AJ251509.1, AC073834.6 and AI919276.1. On May 31, 2019 this sequence version replaced NM_001077196.1. Transcript Variant: This variant (1) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 4. The resulting isoform (1) has a shorter N-terminus, compared to isoform 4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ251509.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCCCCAA AGTGCAGTGC TGATGCTGAG AACAGTTTCA AAGAAAGCAT GGAGAAATCA 
TCATACTCCG ACTGGCTAAT AAATAACAGC ATTGCTGAGC TGGTTGCTTC AACAGGCCTT 
CCAGTGAACA TCAGTGATGC CTACCAGGAT CCGCGCTTTG ATGCAGAGGC AGACCAGATA 
TCTGGTTTTC ACATAAGATC TGTTCTTTGT GTCCCTATTT GGAATAGCAA CCACCAAATA 
ATTGGAGTGG CTCAAGTGTT AAACAGACTT GATGGGAAAC CTTTTGATGA TGCAGATCAA 
CGACTTTTTG AGGCTTTTGT CATCTTTTGT GGACTTGGCA TCAACAACAC AATTATGTAT 
GATCAAGTGA AGAAGTCCTG GGCCAAGCAG TCTGTGGCTC TTGATGTGCT ATCATACCAT 
GCAACATGTT CAAAAGCTGA AGTTGACAAG TTTAAGGCAG CCAACATCCC TCTGGTGTCA 
GAACTTGCCA TCGATGACAT TCATTTTGAT GACTTTTCTC TCGACGTTGA TGCCATGATC 
ACAGCTGCTC TCCGGATGTT CATGGAGCTG GGGATGGTAC AGAAATTTAA AATTGACTAT 
GAGACACTGT GTAGGTGGCT TTTGACAGTG AGGAAAAACT ATCGGATGGT TCTATACCAC 
AACTGGAGAC ATGCCTTCAA CGTGTGTCAG CTGATGTTCG CGATGTTAAC CACTGCTGGG 
TTTCAAGACA TTCTGACCGA GGTGGAAATT TTAGCGGTGA TTGTGGGATG CCTGTGTCAT 
GACCTCGACC ACAGGGGAAC CAACAATGCC TTCCAAGCTA AGAGTGGCTC TGCCCTGGCC 
CAACTCTATG GAACCTCTGC TACCTTGGAG CATCACCATT TCAACCACGC CGTGATGATC 
CTTCAAAGTG AGGGTCACAA TATCTTTGCT AACCTGTCCT CCAAGGAATA TAGTGACCTT 
ATGCAGCTTT TGAAGCAGTC AATATTGGCA ACAGACCTCA CGCTGTACTT TGAGAGGAGA 
ACTGAATTCT TTGAACTTGT CAGTAAAGGA GAATACGATT GGAACATCAA AAACCATCGT 
GATATATTTC GATCAATGTT AATGACAGCC TGTGACCTTG GAGCCGTGAC CAAACCGTGG 
GAGATCTCCA GACAGGTGGC AGAACTTGTA ACCAGTGAGT TCTTCGAACA AGGAGATCGG 
GAGAGATTAG AGCTCAAACT CACTCCTTCA GCAATTTTTG ATCGGAACCG GAAGGATGAA 
CTGCCTCGGT TGCAACTGGA GTGGATTGAT AGCATCTGCA TGCCTTTGTA TCAGGCACTG 
GTGAAGGTCA ACGTGAAACT GAAGCCGATG CTAGATTCAG TAGCTACAAA CAGAAGTAAG 
TGGGAAGAGC TACACCAAAA ACGACTGCTG GCCTCAACTG CCTCATCCTC CCCTGCCAGT 
GTTATGGTAG CCAAGGAAGA CAGGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070664.1
CDS	169..1638
Translation	MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPASVMVAKEDRN

Target ORF information:

RefSeq Version	NM_001077196.2
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077196.2

ORF Insert Sequence:

ATGTCCCCAA AGTGCAGTGC TGATGCTGAG AACAGTTTCA AAGAAAGCAT GGAGAAATCA 
TCATACTCCG ACTGGCTAAT AAATAACAGC ATTGCTGAGC TGGTTGCTTC AACAGGCCTT 
CCAGTGAACA TCAGTGATGC CTACCAGGAT CCGCGCTTTG ATGCAGAGGC AGACCAGATA 
TCTGGTTTTC ACATAAGATC TGTTCTTTGT GTCCCTATTT GGAATAGCAA CCACCAAATA 
ATTGGAGTGG CTCAAGTGTT AAACAGACTT GATGGGAAAC CTTTTGATGA TGCAGATCAA 
CGACTTTTTG AGGCTTTTGT CATCTTTTGT GGACTTGGCA TCAACAACAC AATTATGTAT 
GATCAAGTGA AGAAGTCCTG GGCCAAGCAG TCTGTGGCTC TTGATGTGCT ATCATACCAT 
GCAACATGTT CAAAAGCTGA AGTTGACAAG TTTAAGGCAG CCAACATCCC TCTGGTGTCA 
GAACTTGCCA TCGATGACAT TCATTTTGAT GACTTTTCTC TCGACGTTGA TGCCATGATC 
ACAGCTGCTC TCCGGATGTT CATGGAGCTG GGGATGGTAC AGAAATTTAA AATTGACTAT 
GAGACACTGT GTAGGTGGCT TTTGACAGTG AGGAAAAACT ATCGGATGGT TCTATACCAC 
AACTGGAGAC ATGCCTTCAA CGTGTGTCAG CTGATGTTCG CGATGTTAAC CACTGCTGGG 
TTTCAAGACA TTCTGACCGA GGTGGAAATT TTAGCGGTGA TTGTGGGATG CCTGTGTCAT 
GACCTCGACC ACAGGGGAAC CAACAATGCC TTCCAAGCTA AGAGTGGCTC TGCCCTGGCC 
CAACTCTATG GAACCTCTGC TACCTTGGAG CATCACCATT TCAACCACGC CGTGATGATC 
CTTCAAAGTG AGGGTCACAA TATCTTTGCT AACCTGTCCT CCAAGGAATA TAGTGACCTT 
ATGCAGCTTT TGAAGCAGTC AATATTGGCA ACAGACCTCA CGCTGTACTT TGAGAGGAGA 
ACTGAATTCT TTGAACTTGT CAGTAAAGGA GAATACGATT GGAACATCAA AAACCATCGT 
GATATATTTC GATCAATGTT AATGACAGCC TGTGACCTTG GAGCCGTGAC CAAACCGTGG 
GAGATCTCCA GACAGGTGGC AGAACTTGTA ACCAGTGAGT TCTTCGAACA AGGAGATCGG 
GAGAGATTAG AGCTCAAACT CACTCCTTCA GCAATTTTTG ATCGGAACCG GAAGGATGAA 
CTGCCTCGGT TGCAACTGGA GTGGATTGAT AGCATCTGCA TGCCTTTGTA TCAGGCACTG 
GTGAAGGTCA ACGTGAAACT GAAGCCGATG CTAGATTCAG TAGCTACAAA CAGAAGTAAG 
TGGGAAGAGC TACACCAAAA ACGACTGCTG GCCTCAACTG CCTCATCCTC CCCTGCCAGT 
GTTATGGTAG CCAAGGAAGA CAGGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDE11A ( NM_001077197.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001070665.1 Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu18294
Clone ID Related Accession (Same CDS sequence)	NM_001077197.1
Accession Version	NM_001077197.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2052bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB038041.1, AC073892.6, AC073834.6 and AI919276.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (3) contains a distinct 5' UTR and 5' coding region, compared to variant 4. The resulting isoform (3) contains a shorter and distinct N-terminus, compared to isoform 4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB038041.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCTGAAGC AGGCAAGAAG ACCTTTATTC AGAAATGTGC TCAGTGCCAC ACAGTGGAAA 
AAGGTGAAAA TCACAAGACT GGTCCAAATC TCTGGGGCCT CTTTGGCTGA AAAACAGGAA 
AAGCACCAGG ATTTTCTTAT ACAGAGGCAA ACAAAAACAA AGGATCGACG ATTCAATGAT 
GAAATCGACA AGCTAACTGG ATACAAGACA AAATCATTAT TGTGCATGCC TATCCGAAGC 
AGTGATGGTG AGATTATTGG TGTGGCCCAA GCGATAAATA AGATTCCTGA AGGAGCTCCA 
TTTACTGAAG ATGATGAAAA AGTTATGCAG ATGTATCTTC CATTTTGTGG AATCGCCATA 
TCTAACGCTC AGCTCTTTGC TGCCTCAAGG AAAGAATATG AAAGAAGCAG AGCTTTGCTA 
GAGGTGGTTA ATGACCTCTT TGAAGAACAG ACTGACCTGG AGAAAATTGT CAAGAAAATA 
ATGCATCGGG CCCAAACTCT GCTGAAATGT GAACGCTGTT CTGTTTTACT CCTAGAGGAC 
ATCGAATCAC CAGTGGTGAA ATTTACCAAA TCCTTTGAAT TGATGTCCCC AAAGTGCAGT 
GCTGATGCTG AGAACAGTTT CAAAGAAAGC ATGGAGAAAT CATCATACTC CGACTGGCTA 
ATAAATAACA GCATTGCTGA GCTGGTTGCT TCAACAGGCC TTCCAGTGAA CATCAGTGAT 
GCCTACCAGG ATCCGCGCTT TGATGCAGAG GCAGACCAGA TATCTGGTTT TCACATAAGA 
TCTGTTCTTT GTGTCCCTAT TTGGAATAGC AACCACCAAA TAATTGGAGT GGCTCAAGTG 
TTAAACAGAC TTGATGGGAA ACCTTTTGAT GATGCAGATC AACGACTTTT TGAGGCTTTT 
GTCATCTTTT GTGGACTTGG CATCAACAAC ACAATTATGT ATGATCAAGT GAAGAAGTCC 
TGGGCCAAGC AGTCTGTGGC TCTTGATGTG CTATCATACC ATGCAACATG TTCAAAAGCT 
GAAGTTGACA AGTTTAAGGC AGCCAACATC CCTCTGGTGT CAGAACTTGC CATCGATGAC 
ATTCATTTTG ATGACTTTTC TCTCGACGTT GATGCCATGA TCACAGCTGC TCTCCGGATG 
TTCATGGAGC TGGGGATGGT ACAGAAATTT AAAATTGACT ATGAGACACT GTGTAGGTGG 
CTTTTGACAG TGAGGAAAAA CTATCGGATG GTTCTATACC ACAACTGGAG ACATGCCTTC 
AACGTGTGTC AGCTGATGTT CGCGATGTTA ACCACTGCTG GGTTTCAAGA CATTCTGACC 
GAGGTGGAAA TTTTAGCGGT GATTGTGGGA TGCCTGTGTC ATGACCTCGA CCACAGGGGA 
ACCAACAATG CCTTCCAAGC TAAGAGTGGC TCTGCCCTGG CCCAACTCTA TGGAACCTCT 
GCTACCTTGG AGCATCACCA TTTCAACCAC GCCGTGATGA TCCTTCAAAG TGAGGGTCAC 
AATATCTTTG CTAACCTGTC CTCCAAGGAA TATAGTGACC TTATGCAGCT TTTGAAGCAG 
TCAATATTGG CAACAGACCT CACGCTGTAC TTTGAGAGGA GAACTGAATT CTTTGAACTT 
GTCAGTAAAG GAGAATACGA TTGGAACATC AAAAACCATC GTGATATATT TCGATCAATG 
TTAATGACAG CCTGTGACCT TGGAGCCGTG ACCAAACCGT GGGAGATCTC CAGACAGGTG 
GCAGAACTTG TAACCAGTGA GTTCTTCGAA CAAGGAGATC GGGAGAGATT AGAGCTCAAA 
CTCACTCCTT CAGCAATTTT TGATCGGAAC CGGAAGGATG AACTGCCTCG GTTGCAACTG 
GAGTGGATTG ATAGCATCTG CATGCCTTTG TATCAGGCAC TGGTGAAGGT CAACGTGAAA 
CTGAAGCCGA TGCTAGATTC AGTAGCTACA AACAGAAGTA AGTGGGAAGA GCTACACCAA 
AAACGACTGC TGGCCTCAAC TGCCTCATCC TCCCCTGCCA GTGTTATGGT AGCCAAGGAA 
GACAGGAACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070665.1
CDS	100..2151
Translation	MLKQARRPLFRNVLSATQWKKVKITRLVQISGASLAEKQEKHQDFLIQRQTKTKDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPASVMVAKEDRN

Target ORF information:

RefSeq Version	NM_001077197.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077197.1

ORF Insert Sequence:

ATGCTGAAGC AGGCAAGAAG ACCTTTATTC AGAAATGTGC TCAGTGCCAC ACAGTGGAAA 
AAGGTGAAAA TCACAAGACT GGTCCAAATC TCTGGGGCCT CTTTGGCTGA AAAACAGGAA 
AAGCACCAGG ATTTTCTTAT ACAGAGGCAA ACAAAAACAA AGGATCGACG ATTCAATGAT 
GAAATCGACA AGCTAACTGG ATACAAGACA AAATCATTAT TGTGCATGCC TATCCGAAGC 
AGTGATGGTG AGATTATTGG TGTGGCCCAA GCGATAAATA AGATTCCTGA AGGAGCTCCA 
TTTACTGAAG ATGATGAAAA AGTTATGCAG ATGTATCTTC CATTTTGTGG AATCGCCATA 
TCTAACGCTC AGCTCTTTGC TGCCTCAAGG AAAGAATATG AAAGAAGCAG AGCTTTGCTA 
GAGGTGGTTA ATGACCTCTT TGAAGAACAG ACTGACCTGG AGAAAATTGT CAAGAAAATA 
ATGCATCGGG CCCAAACTCT GCTGAAATGT GAACGCTGTT CTGTTTTACT CCTAGAGGAC 
ATCGAATCAC CAGTGGTGAA ATTTACCAAA TCCTTTGAAT TGATGTCCCC AAAGTGCAGT 
GCTGATGCTG AGAACAGTTT CAAAGAAAGC ATGGAGAAAT CATCATACTC CGACTGGCTA 
ATAAATAACA GCATTGCTGA GCTGGTTGCT TCAACAGGCC TTCCAGTGAA CATCAGTGAT 
GCCTACCAGG ATCCGCGCTT TGATGCAGAG GCAGACCAGA TATCTGGTTT TCACATAAGA 
TCTGTTCTTT GTGTCCCTAT TTGGAATAGC AACCACCAAA TAATTGGAGT GGCTCAAGTG 
TTAAACAGAC TTGATGGGAA ACCTTTTGAT GATGCAGATC AACGACTTTT TGAGGCTTTT 
GTCATCTTTT GTGGACTTGG CATCAACAAC ACAATTATGT ATGATCAAGT GAAGAAGTCC 
TGGGCCAAGC AGTCTGTGGC TCTTGATGTG CTATCATACC ATGCAACATG TTCAAAAGCT 
GAAGTTGACA AGTTTAAGGC AGCCAACATC CCTCTGGTGT CAGAACTTGC CATCGATGAC 
ATTCATTTTG ATGACTTTTC TCTCGACGTT GATGCCATGA TCACAGCTGC TCTCCGGATG 
TTCATGGAGC TGGGGATGGT ACAGAAATTT AAAATTGACT ATGAGACACT GTGTAGGTGG 
CTTTTGACAG TGAGGAAAAA CTATCGGATG GTTCTATACC ACAACTGGAG ACATGCCTTC 
AACGTGTGTC AGCTGATGTT CGCGATGTTA ACCACTGCTG GGTTTCAAGA CATTCTGACC 
GAGGTGGAAA TTTTAGCGGT GATTGTGGGA TGCCTGTGTC ATGACCTCGA CCACAGGGGA 
ACCAACAATG CCTTCCAAGC TAAGAGTGGC TCTGCCCTGG CCCAACTCTA TGGAACCTCT 
GCTACCTTGG AGCATCACCA TTTCAACCAC GCCGTGATGA TCCTTCAAAG TGAGGGTCAC 
AATATCTTTG CTAACCTGTC CTCCAAGGAA TATAGTGACC TTATGCAGCT TTTGAAGCAG 
TCAATATTGG CAACAGACCT CACGCTGTAC TTTGAGAGGA GAACTGAATT CTTTGAACTT 
GTCAGTAAAG GAGAATACGA TTGGAACATC AAAAACCATC GTGATATATT TCGATCAATG 
TTAATGACAG CCTGTGACCT TGGAGCCGTG ACCAAACCGT GGGAGATCTC CAGACAGGTG 
GCAGAACTTG TAACCAGTGA GTTCTTCGAA CAAGGAGATC GGGAGAGATT AGAGCTCAAA 
CTCACTCCTT CAGCAATTTT TGATCGGAAC CGGAAGGATG AACTGCCTCG GTTGCAACTG 
GAGTGGATTG ATAGCATCTG CATGCCTTTG TATCAGGCAC TGGTGAAGGT CAACGTGAAA 
CTGAAGCCGA TGCTAGATTC AGTAGCTACA AACAGAAGTA AGTGGGAAGA GCTACACCAA 
AAACGACTGC TGGCCTCAAC TGCCTCATCC TCCCCTGCCA GTGTTATGGT AGCCAAGGAA 
GACAGGAACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A stop-codon of the phosphodiesterase 11A gene is associated with elevated blood pressure and measures of obesity.
Journal of hypertension34(3)445-51; discussion 451(2016 Mar)
Ohlsson T,Lindgren A,Engstr?m G,Jern C,Melander O

Rare inactivating PDE11A variants associated with testicular germ cell tumors.
Endocrine-related cancer22(6)909-17(2015 Dec)
Pathak A,Stewart DR,Faucz FR,Xekouki P,Bass S,Vogt A,Zhang X,Boland J,Yeager M,Loud JT,Nathanson KL,McGlynn KA,Stratakis CA,Greene MH,Mirabello L

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
Nature genetics45(6)621-31(2013 Jun)
den Hoed M,Eijgelsheim M,Esko T,Brundel BJ,Peal DS,Evans DM,Nolte IM,Segr? AV,Holm H,Handsaker RE,Westra HJ,Johnson T,Isaacs A,Yang J,Lundby A,Zhao JH,Kim YJ,Go MJ,Almgren P,Bochud M,Boucher G,Cornelis MC,Gudbjartsson D,Hadley D,van der Harst P,Hayward C,den Heijer M,Igl W,Jackson AU,Kutalik Z,Luan J,Kemp JP,Kristiansson K,Ladenvall C,Lorentzon M,Montasser ME,Njajou OT,O'Reilly PF,Padmanabhan S,St Pourcain B,Rankinen T,Salo P,Tanaka T,Timpson NJ,Vitart V,Waite L,Wheeler W,Zhang W,Draisma HH,Feitosa MF,Kerr KF,Lind PA,Mihailov E,Onland-Moret NC,Song C,Weedon MN,Xie W,Yengo L,Absher D,Albert CM,Alonso A,Arking DE,de Bakker PI,Balkau B,Barlassina C,Benaglio P,Bis JC,Bouatia-Naji N,Brage S,Chanock SJ,Chines PS,Chung M,Darbar D,Dina C,D?rr M,Elliott P,Felix SB,Fischer K,Fuchsberger C,de Geus EJ,Goyette P,Gudnason V,Harris TB,Hartikainen AL,Havulinna AS,Heckbert SR,Hicks AA,Hofman A,Holewijn S,Hoogstra-Berends F,Hottenga JJ,Jensen MK,Johansson A,Junttila J,K??b S,Kanon B,Ketkar S,Khaw KT,Knowles JW,Kooner AS,Kors JA,Kumari M,Milani L,Laiho P,Lakatta EG,Langenberg C,Leusink M,Liu Y,Luben RN,Lunetta KL,Lynch SN,Markus MR,Marques-Vidal P,Mateo Leach I,McArdle WL,McCarroll SA,Medland SE,Miller KA,Montgomery GW,Morrison AC,M?ller-Nurasyid M,Navarro P,Nelis M,O'Connell JR,O'Donnell CJ,Ong KK,Newman AB,Peters A,Polasek O,Pouta A,Pramstaller PP,Psaty BM,Rao DC,Ring SM,Rossin EJ,Rudan D,Sanna S,Scott RA,Sehmi JS,Sharp S,Shin JT,Singleton AB,Smith AV,Soranzo N,Spector TD,Stewart C,Stringham HM,Tarasov KV,Uitterlinden AG,Vandenput L,Hwang SJ,Whitfield JB,Wijmenga C,Wild SH,Willemsen G,Wilson JF,Witteman JC,Wong A,Wong Q,Jamshidi Y,Zitting P,Boer JM,Boomsma DI,Borecki IB,van Duijn CM,Ekelund U,Forouhi NG,Froguel P,Hingorani A,Ingelsson E,Kivimaki M,Kronmal RA,Kuh D,Lind L,Martin NG,Oostra BA,Pedersen NL,Quertermous T,Rotter JI,van der Schouw YT,Verschuren WM,Walker M,Albanes D,Arnar DO,Assimes TL,Bandinelli S,Boehnke M,de Boer RA,Bouchard C,Caulfield WL,Chambers JC,Curhan G,Cusi D,Eriksson J,Ferrucci L,van Gilst WH,Glorioso N,de Graaf J,Groop L,Gyllensten U,Hsueh WC,Hu FB,Huikuri HV,Hunter DJ,Iribarren C,Isomaa B,Jarvelin MR,Jula A,K?h?nen M,Kiemeney LA,van der Klauw MM,Kooner JS,Kraft P,Iacoviello L,Lehtim?ki T,Lokki ML,Mitchell BD,Navis G,Nieminen MS,Ohlsson C,Poulter NR,Qi L,Raitakari OT,Rimm EB,Rioux JD,Rizzi F,Rudan I,Salomaa V,Sever PS,Shields DC,Shuldiner AR,Sinisalo J,Stanton AV,Stolk RP,Strachan DP,Tardif JC,Thorsteinsdottir U,Tuomilehto J,van Veldhuisen DJ,Virtamo J,Viikari J,Vollenweider P,Waeber G,Widen E,Cho YS,Olsen JV,Visscher PM,Willer C,Franke L,,,Erdmann J,Thompson JR,,Pfeufer A,,Sotoodehnia N,,Newton-Cheh C,,Ellinor PT,Stricker BH,Metspalu A,Perola M,Beckmann JS,Smith GD,Stefansson K,Wareham NJ,Munroe PB,Sibon OC,Milan DJ,Snieder H,Samani NJ,Loos RJ

Phosphodiesterase 11A (PDE11A) gene defects in patients with acth-independent macronodular adrenal hyperplasia (AIMAH): functional variants may contribute to genetic susceptibility of bilateral adrenal tumors.
The Journal of clinical endocrinology and metabolism97(11)E2063-9(2012 Nov)
Vezzosi D,Lib? R,Baudry C,Rizk-Rabin M,Horvath A,Levy I,Ren?-Corail F,Ragazzon B,Stratakis CA,Vandecasteele G,Bertherat J

Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5).
International journal of impotence research23(5)206-12(2011 Sep-Oct)
?ckert S,Oelke M,Albrecht K,Breitmeier D,Kuczyk MA,Hedlund P

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

[email protected]

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

PDE11A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム