TRIM58 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TRIM58
Entrez Gene ID	25893
Full Name	tripartite motif containing 58
Synonyms	BIA2
General protein information	Preferred Names tripartite motif containing 58 Names E3 ubiquitin-protein ligase TRIM58 RING-type E3 ubiquitin transferase TRIM58 tripartite motif-containing protein 58
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q44

mRNA and Protein(s)

mRNA	Protein	Name
NM_015431.4	NP_056246.3	E3 ubiquitin-protein ligase TRIM58
NM_015431.3	NP_056246.3	E3 ubiquitin-protein ligase TRIM58

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Trim58	NP_001178570.1
	TRIM58	XP_001086222.1
Pan troglodytes (chimpanzee)	TRIM58	XP_524544.3
Bos taurus (cattle)	TRIM58	XP_002689127.1
Homo sapiens (human)	TRIM58	NP_056246.3
Canis lupus familiaris (dog)	TRIM58	XP_005628415.1
Gallus gallus (chicken)	LOC770718	XP_001232970.3
Mus musculus (house mouse)	Trim58	NP_001034136.1

Gene Ontology
Bibliography

Related articles in PubMed

Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma.
Kajiura K, Masuda K, Naruto T, Kohmoto T, Watabnabe M, Tsuboi M, Takizawa H, Kondo K, Tangoku A, Imoto I
Oncotarget8(2)2890-2905(2017 Jan)

Seventy-five genetic loci influencing the human red blood cell.
van der Harst P, Zhang W, Mateo Leach I, Rendon A, Verweij N, Sehmi J, Paul DS, Elling U, Allayee H, Li X, Radhakrishnan A, Tan ST, Voss K, Weichenberger CX, Albers CA, Al-Hussani A, Asselbergs FW, Ciullo M, Danjou F, Dina C, Esko T, Evans DM, Franke L, G?gele M, Hartiala J, Hersch M, Holm H, Hottenga JJ, Kanoni S, Kleber ME, Lagou V, Langenberg C, Lopez LM, Lyytik?inen LP, Melander O, Murgia F, Nolte IM, O'Reilly PF, Padmanabhan S, Parsa A, Pirastu N, Porcu E, Portas L, Prokopenko I, Ried JS, Shin SY, Tang CS, Teumer A, Traglia M, Ulivi S, Westra HJ, Yang J, Zhao JH, Anni F, Abdellaoui A, Attwood A, Balkau B, Bandinelli S, Bastardot F, Benyamin B, Boehm BO, Cookson WO, Das D, de Bakker PI, de Boer RA, de Geus EJ, de Moor MH, Dimitriou M, Domingues FS, D?ring A, Engstr?m G, Eyjolfsson GI, Ferrucci L, Fischer K, Galanello R, Garner SF, Genser B, Gibson QD, Girotto G, Gudbjartsson DF, Harris SE, Hartikainen AL, Hastie CE, Hedblad B, Illig T, Jolley J, K?h?nen M, Kema IP, Kemp JP, Liang L, Lloyd-Jones H, Loos RJ, Meacham S, Medland SE, Meisinger C, Memari Y, Mihailov E, Miller K, Moffatt MF, Nauck M, Novatchkova M, Nutile T, Olafsson I, Onundarson PT, Parracciani D, Penninx BW, Perseu L, Piga A, Pistis G, Pouta A, Puc U, Raitakari O, Ring SM, Robino A, Ruggiero D, Ruokonen A, Saint-Pierre A, Sala C, Salumets A, Sambrook J, Schepers H, Schmidt CO, Sillj? HH, Sladek R, Smit JH, Starr JM, Stephens J, Sulem P, Tanaka T, Thorsteinsdottir U, Tragante V, van Gilst WH, van Pelt LJ, van Veldhuisen DJ, V?lker U, Whitfield JB, Willemsen G, Winkelmann BR, Wirnsberger G, Algra A, Cucca F, d'Adamo AP, Danesh J, Deary IJ, Dominiczak AF, Elliott P, Fortina P, Froguel P, Gasparini P, Greinacher A, Hazen SL, Jarvelin MR, Khaw KT, Lehtim?ki T, Maerz W, Martin NG, Metspalu A, Mitchell BD, Montgomery GW, Moore C, Navis G, Pirastu M, Pramstaller PP, Ramirez-Solis R, Schadt E, Scott J, Shuldiner AR, Smith GD, Smith JG, Snieder H, Sorice R, Spector TD, Stefansson K, Stumvoll M, Tang WH, Toniolo D, T?njes A, Visscher PM, Vollenweider P, Wareham NJ, Wolffenbuttel BH, Boomsma DI, Beckmann JS, Dedoussis GV, Deloukas P, Ferreira MA, Sanna S, Uda M, Hicks AA, Penninger JM, Gieger C, Kooner JS, Ouwehand WH, Soranzo N, Chambers JC
Nature492(7429)369-75(2012 Dec)

New gene functions in megakaryopoiesis and platelet formation.
Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y, Lopez LM, M?gi R, Meacham S, Okada Y, Pirastu N, Sorice R, Teumer A, Voss K, Zhang W, Ramirez-Solis R, Bis JC, Ellinghaus D, G?gele M, Hottenga JJ, Langenberg C, Kovacs P, O'Reilly PF, Shin SY, Esko T, Hartiala J, Kanoni S, Murgia F, Parsa A, Stephens J, van der Harst P, Ellen van der Schoot C, Allayee H, Attwood A, Balkau B, Bastardot F, Basu S, Baumeister SE, Biino G, Bomba L, Bonnefond A, Cambien F, Chambers JC, Cucca F, D'Adamo P, Davies G, de Boer RA, de Geus EJ, D?ring A, Elliott P, Erdmann J, Evans DM, Falchi M, Feng W, Folsom AR, Frazer IH, Gibson QD, Glazer NL, Hammond C, Hartikainen AL, Heckbert SR, Hengstenberg C, Hersch M, Illig T, Loos RJ, Jolley J, Khaw KT, K?hnel B, Kyrtsonis MC, Lagou V, Lloyd-Jones H, Lumley T, Mangino M, Maschio A, Mateo Leach I, McKnight B, Memari Y, Mitchell BD, Montgomery GW, Nakamura Y, Nauck M, Navis G, N?thlings U, Nolte IM, Porteous DJ, Pouta A, Pramstaller PP, Pullat J, Ring SM, Rotter JI, Ruggiero D, Ruokonen A, Sala C, Samani NJ, Sambrook J, Schlessinger D, Schreiber S, Schunkert H, Scott J, Smith NL, Snieder H, Starr JM, Stumvoll M, Takahashi A, Tang WH, Taylor K, Tenesa A, Lay Thein S, T?njes A, Uda M, Ulivi S, van Veldhuisen DJ, Visscher PM, V?lker U, Wichmann HE, Wiggins KL, Willemsen G, Yang TP, Hua Zhao J, Zitting P, Bradley JR, Dedoussis GV, Gasparini P, Hazen SL, Metspalu A, Pirastu M, Shuldiner AR, Joost van Pelt L, Zwaginga JJ, Boomsma DI, Deary IJ, Franke A, Froguel P, Ganesh SK, Jarvelin MR, Martin NG, Meisinger C, Psaty BM, Spector TD, Wareham NJ, Akkerman JW, Ciullo M, Deloukas P, Greinacher A, Jupe S, Kamatani N, Khadake J, Kooner JS, Penninger J, Prokopenko I, Stemple D, Toniolo D, Wernisch L, Sanna S, Hicks AA, Rendon A, Ferreira MA, Ouwehand WH, Soranzo N
Nature480(7376)201-8(2011 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TRIM58 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRIM58 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30188	NM_015431.4 Latest version!	Homo sapiens tripartite motif containing 58 (TRIM58), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$286.30 $409.00
View Old Accession Versions >>
OHu30188	NM_015431.3	Homo sapiens tripartite motif containing 58 (TRIM58), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$286.30 $409.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TRIM58 ( NM_015431.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056246.3 Homo sapiens tripartite motif containing 58 (TRIM58), mRNA.

Price & Availability↑

CloneID	OHu30188
Clone ID Related Accession (Same CDS sequence)	NM_015431.4 , NM_015431.3
Accession Version	NM_015431.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase TRIM58
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099571.3, AF327057.1, DN998591.1 and BX644877.1. On Nov 22, 2018 this sequence version replaced NM_015431.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.206945.1, SRR1803612.21071.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000366481.4/ ENSP00000355437.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCTGGG CGCCGCCCGG GGAGCGGCTG CGCGAGGATG CGCGGTGCCC GGTGTGCCTG 
GATTTCCTGC AGGAGCCGGT CAGCGTGGAC TGCGGCCACA GCTTCTGCCT CAGGTGCATC 
TCCGAGTTCT GCGAGAAGTC GGACGGCGCG CAGGGCGGCG TCTACGCCTG TCCGCAGTGC 
CGGGGCCCCT TCCGGCCCTC GGGCTTTCGC CCCAACCGGC AGCTGGCGGG CCTGGTGGAG 
AGCGTGCGGC GGCTGGGGTT GGGCGCGGGG CCCGGGGCGC GGCGATGCGC GCGGCACGGC 
GAGGACCTGA GCCGCTTCTG CGAGGAGGAC GAGGCGGCGC TGTGCTGGGT GTGCGACGCC 
GGCCCCGAGC ACAGGACGCA CCGCACGGCG CCGCTGCAGG AGGCCGCCGG CAGCTACCAG 
GTAAAGCTCC AGATGGCTCT GGAACTTATG AGGAAAGAGT TGGAGGACGC CTTGACTCAG 
GAGGCCAACG TGGGGAAAAA GACTGTCATT TGGAAGGAGA AAGTGGAAAT GCAGAGGCAG 
CGCTTCAGAT TGGAGTTTGA GAAGCATCGT GGCTTTCTGG CCCAGGAGGA GCAACGGCAG 
CTGAGGCGGC TGGAGGCGGA GGAGCGAGCG ACGCTGCAGA GACTGCGGGA GAGCAAGAGC 
CGGCTGGTCC AGCAGAGCAA GGCCCTGAAG GAGCTGGCGG ATGAGCTGCA GGAGAGGTGC 
CAGCGCCCGG CCCTGGGTCT GCTGGAGGGT GTGAGAGGAG TCCTGAGCAG AAGTAAGGCT 
GTCACAAGGC TGGAAGCAGA GAACATCCCC ATGGAACTGA AGACAGCATG CTGCATCCCT 
GGGAGGAGGG AGCTCTTAAG GAAGTTCCAA GTGGATGTAA AGCTGGATCC CGCCACGGCG 
CACCCGAGTC TGCTCTTGAC CGCCGACCTG CGCAGTGTGC AGGATGGAGA ACCATGGAGG 
GATGTCCCCA ACAACCCTGA GCGATTTGAC ACATGGCCCT GCATCCTGGG TTTGCAGAGC 
TTCTCATCAG GGAGGCATTA CTGGGAGGTT CTGGTGGGAG AAGGAGCAGA GTGGGGTTTA 
GGGGTCTGTC AAGACACACT GCCAAGAAAG GGGGAAACCA CGCCATCTCC TGAGAATGGG 
GTCTGGGCCC TGTGGCTGCT GAAAGGGAAT GAGTACATGG TCCTTGCCTC CCCATCAGTG 
CCTCTTCTCC AACTGGAAAG TCCTCGCTGC ATTGGGATTT TCTTGGACTA TGAAGCCGGT 
GAAATTTCAT TCTACAATGT CACAGATGGA TCTTATATCT ACACATTCAA CCAACTCTTC 
TCTGGTCTTC TTCGGCCTTA CTTTTTCATC TGTGATGCAA CTCCTCTTAT CTTGCCACCC 
ACAACAATAG CAGGGTCAGG AAATTGGGCA TCCAGGGATC ATTTAGATCC TGCTTCTGAT 
GTAAGAGATG ATCATCTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056246.3
CDS	61..1521
Translation	MAWAPPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFICDATPLILPPTTIAGSGNWASRDHLDPASDVRDDHL

Target ORF information:

RefSeq Version	NM_015431.4
Organism	Homo sapiens(human)
Definition	Homo sapiens tripartite motif containing 58 (TRIM58), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015431.4

ORF Insert Sequence:

ATGGCCTGGG CGCCGCCCGG GGAGCGGCTG CGCGAGGATG CGCGGTGCCC GGTGTGCCTG 
GATTTCCTGC AGGAGCCGGT CAGCGTGGAC TGCGGCCACA GCTTCTGCCT CAGGTGCATC 
TCCGAGTTCT GCGAGAAGTC GGACGGCGCG CAGGGCGGCG TCTACGCCTG TCCGCAGTGC 
CGGGGCCCCT TCCGGCCCTC GGGCTTTCGC CCCAACCGGC AGCTGGCGGG CCTGGTGGAG 
AGCGTGCGGC GGCTGGGGTT GGGCGCGGGG CCCGGGGCGC GGCGATGCGC GCGGCACGGC 
GAGGACCTGA GCCGCTTCTG CGAGGAGGAC GAGGCGGCGC TGTGCTGGGT GTGCGACGCC 
GGCCCCGAGC ACAGGACGCA CCGCACGGCG CCGCTGCAGG AGGCCGCCGG CAGCTACCAG 
GTAAAGCTCC AGATGGCTCT GGAACTTATG AGGAAAGAGT TGGAGGACGC CTTGACTCAG 
GAGGCCAACG TGGGGAAAAA GACTGTCATT TGGAAGGAGA AAGTGGAAAT GCAGAGGCAG 
CGCTTCAGAT TGGAGTTTGA GAAGCATCGT GGCTTTCTGG CCCAGGAGGA GCAACGGCAG 
CTGAGGCGGC TGGAGGCGGA GGAGCGAGCG ACGCTGCAGA GACTGCGGGA GAGCAAGAGC 
CGGCTGGTCC AGCAGAGCAA GGCCCTGAAG GAGCTGGCGG ATGAGCTGCA GGAGAGGTGC 
CAGCGCCCGG CCCTGGGTCT GCTGGAGGGT GTGAGAGGAG TCCTGAGCAG AAGTAAGGCT 
GTCACAAGGC TGGAAGCAGA GAACATCCCC ATGGAACTGA AGACAGCATG CTGCATCCCT 
GGGAGGAGGG AGCTCTTAAG GAAGTTCCAA GTGGATGTAA AGCTGGATCC CGCCACGGCG 
CACCCGAGTC TGCTCTTGAC CGCCGACCTG CGCAGTGTGC AGGATGGAGA ACCATGGAGG 
GATGTCCCCA ACAACCCTGA GCGATTTGAC ACATGGCCCT GCATCCTGGG TTTGCAGAGC 
TTCTCATCAG GGAGGCATTA CTGGGAGGTT CTGGTGGGAG AAGGAGCAGA GTGGGGTTTA 
GGGGTCTGTC AAGACACACT GCCAAGAAAG GGGGAAACCA CGCCATCTCC TGAGAATGGG 
GTCTGGGCCC TGTGGCTGCT GAAAGGGAAT GAGTACATGG TCCTTGCCTC CCCATCAGTG 
CCTCTTCTCC AACTGGAAAG TCCTCGCTGC ATTGGGATTT TCTTGGACTA TGAAGCCGGT 
GAAATTTCAT TCTACAATGT CACAGATGGA TCTTATATCT ACACATTCAA CCAACTCTTC 
TCTGGTCTTC TTCGGCCTTA CTTTTTCATC TGTGATGCAA CTCCTCTTAT CTTGCCACCC 
ACAACAATAG CAGGGTCAGG AAATTGGGCA TCCAGGGATC ATTTAGATCC TGCTTCTGAT 
GTAAGAGATG ATCATCTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIM58 ( NM_015431.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056246.3 Homo sapiens tripartite motif containing 58 (TRIM58), mRNA.

Price & Availability↑

CloneID	OHu30188
Clone ID Related Accession (Same CDS sequence)	NM_015431.4 , NM_015431.3
Accession Version	NM_015431.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase TRIM58
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF327057.1, DN998591.1, BX644877.1 and AC099571.3. On Aug 17, 2006 this sequence version replaced NM_015431.2. ##Evidence-Data-START## Transcript exon combination :: AF327057.1, SRR1660809.206945.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTGGG CGCCGCCCGG GGAGCGGCTG CGCGAGGATG CGCGGTGCCC GGTGTGCCTG 
GATTTCCTGC AGGAGCCGGT CAGCGTGGAC TGCGGCCACA GCTTCTGCCT CAGGTGCATC 
TCCGAGTTCT GCGAGAAGTC GGACGGCGCG CAGGGCGGCG TCTACGCCTG TCCGCAGTGC 
CGGGGCCCCT TCCGGCCCTC GGGCTTTCGC CCCAACCGGC AGCTGGCGGG CCTGGTGGAG 
AGCGTGCGGC GGCTGGGGTT GGGCGCGGGG CCCGGGGCGC GGCGATGCGC GCGGCACGGC 
GAGGACCTGA GCCGCTTCTG CGAGGAGGAC GAGGCGGCGC TGTGCTGGGT GTGCGACGCC 
GGCCCCGAGC ACAGGACGCA CCGCACGGCG CCGCTGCAGG AGGCCGCCGG CAGCTACCAG 
GTAAAGCTCC AGATGGCTCT GGAACTTATG AGGAAAGAGT TGGAGGACGC CTTGACTCAG 
GAGGCCAACG TGGGGAAAAA GACTGTCATT TGGAAGGAGA AAGTGGAAAT GCAGAGGCAG 
CGCTTCAGAT TGGAGTTTGA GAAGCATCGT GGCTTTCTGG CCCAGGAGGA GCAACGGCAG 
CTGAGGCGGC TGGAGGCGGA GGAGCGAGCG ACGCTGCAGA GACTGCGGGA GAGCAAGAGC 
CGGCTGGTCC AGCAGAGCAA GGCCCTGAAG GAGCTGGCGG ATGAGCTGCA GGAGAGGTGC 
CAGCGCCCGG CCCTGGGTCT GCTGGAGGGT GTGAGAGGAG TCCTGAGCAG AAGTAAGGCT 
GTCACAAGGC TGGAAGCAGA GAACATCCCC ATGGAACTGA AGACAGCATG CTGCATCCCT 
GGGAGGAGGG AGCTCTTAAG GAAGTTCCAA GTGGATGTAA AGCTGGATCC CGCCACGGCG 
CACCCGAGTC TGCTCTTGAC CGCCGACCTG CGCAGTGTGC AGGATGGAGA ACCATGGAGG 
GATGTCCCCA ACAACCCTGA GCGATTTGAC ACATGGCCCT GCATCCTGGG TTTGCAGAGC 
TTCTCATCAG GGAGGCATTA CTGGGAGGTT CTGGTGGGAG AAGGAGCAGA GTGGGGTTTA 
GGGGTCTGTC AAGACACACT GCCAAGAAAG GGGGAAACCA CGCCATCTCC TGAGAATGGG 
GTCTGGGCCC TGTGGCTGCT GAAAGGGAAT GAGTACATGG TCCTTGCCTC CCCATCAGTG 
CCTCTTCTCC AACTGGAAAG TCCTCGCTGC ATTGGGATTT TCTTGGACTA TGAAGCCGGT 
GAAATTTCAT TCTACAATGT CACAGATGGA TCTTATATCT ACACATTCAA CCAACTCTTC 
TCTGGTCTTC TTCGGCCTTA CTTTTTCATC TGTGATGCAA CTCCTCTTAT CTTGCCACCC 
ACAACAATAG CAGGGTCAGG AAATTGGGCA TCCAGGGATC ATTTAGATCC TGCTTCTGAT 
GTAAGAGATG ATCATCTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056246.3
CDS	49..1509
Translation	MAWAPPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFICDATPLILPPTTIAGSGNWASRDHLDPASDVRDDHL

Target ORF information:

RefSeq Version	NM_015431.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tripartite motif containing 58 (TRIM58), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015431.3

ORF Insert Sequence:

ATGGCCTGGG CGCCGCCCGG GGAGCGGCTG CGCGAGGATG CGCGGTGCCC GGTGTGCCTG 
GATTTCCTGC AGGAGCCGGT CAGCGTGGAC TGCGGCCACA GCTTCTGCCT CAGGTGCATC 
TCCGAGTTCT GCGAGAAGTC GGACGGCGCG CAGGGCGGCG TCTACGCCTG TCCGCAGTGC 
CGGGGCCCCT TCCGGCCCTC GGGCTTTCGC CCCAACCGGC AGCTGGCGGG CCTGGTGGAG 
AGCGTGCGGC GGCTGGGGTT GGGCGCGGGG CCCGGGGCGC GGCGATGCGC GCGGCACGGC 
GAGGACCTGA GCCGCTTCTG CGAGGAGGAC GAGGCGGCGC TGTGCTGGGT GTGCGACGCC 
GGCCCCGAGC ACAGGACGCA CCGCACGGCG CCGCTGCAGG AGGCCGCCGG CAGCTACCAG 
GTAAAGCTCC AGATGGCTCT GGAACTTATG AGGAAAGAGT TGGAGGACGC CTTGACTCAG 
GAGGCCAACG TGGGGAAAAA GACTGTCATT TGGAAGGAGA AAGTGGAAAT GCAGAGGCAG 
CGCTTCAGAT TGGAGTTTGA GAAGCATCGT GGCTTTCTGG CCCAGGAGGA GCAACGGCAG 
CTGAGGCGGC TGGAGGCGGA GGAGCGAGCG ACGCTGCAGA GACTGCGGGA GAGCAAGAGC 
CGGCTGGTCC AGCAGAGCAA GGCCCTGAAG GAGCTGGCGG ATGAGCTGCA GGAGAGGTGC 
CAGCGCCCGG CCCTGGGTCT GCTGGAGGGT GTGAGAGGAG TCCTGAGCAG AAGTAAGGCT 
GTCACAAGGC TGGAAGCAGA GAACATCCCC ATGGAACTGA AGACAGCATG CTGCATCCCT 
GGGAGGAGGG AGCTCTTAAG GAAGTTCCAA GTGGATGTAA AGCTGGATCC CGCCACGGCG 
CACCCGAGTC TGCTCTTGAC CGCCGACCTG CGCAGTGTGC AGGATGGAGA ACCATGGAGG 
GATGTCCCCA ACAACCCTGA GCGATTTGAC ACATGGCCCT GCATCCTGGG TTTGCAGAGC 
TTCTCATCAG GGAGGCATTA CTGGGAGGTT CTGGTGGGAG AAGGAGCAGA GTGGGGTTTA 
GGGGTCTGTC AAGACACACT GCCAAGAAAG GGGGAAACCA CGCCATCTCC TGAGAATGGG 
GTCTGGGCCC TGTGGCTGCT GAAAGGGAAT GAGTACATGG TCCTTGCCTC CCCATCAGTG 
CCTCTTCTCC AACTGGAAAG TCCTCGCTGC ATTGGGATTT TCTTGGACTA TGAAGCCGGT 
GAAATTTCAT TCTACAATGT CACAGATGGA TCTTATATCT ACACATTCAA CCAACTCTTC 
TCTGGTCTTC TTCGGCCTTA CTTTTTCATC TGTGATGCAA CTCCTCTTAT CTTGCCACCC 
ACAACAATAG CAGGGTCAGG AAATTGGGCA TCCAGGGATC ATTTAGATCC TGCTTCTGAT 
GTAAGAGATG ATCATCTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma.
Oncotarget8(2)2890-2905(2017 Jan)
Kajiura K,Masuda K,Naruto T,Kohmoto T,Watabnabe M,Tsuboi M,Takizawa H,Kondo K,Tangoku A,Imoto I

Seventy-five genetic loci influencing the human red blood cell.
Nature492(7429)369-75(2012 Dec)
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TRIM58 cDNA ORF clone, Homo sapiens(human)

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