MPC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MPC2
Entrez Gene ID	25874
Full Name	mitochondrial pyruvate carrier 2
Synonyms	BRP44,SLC54A2
General protein information	Preferred Names mitochondrial pyruvate carrier 2 Names mitochondrial pyruvate carrier 2 brain protein 44
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q24.2
Disorder MIM:	614737

mRNA and Protein(s)

mRNA	Protein	Name
XM_006711266.2	XP_006711329.1	mitochondrial pyruvate carrier 2 isoform X1
NM_001143674.3	NP_001137146.1	mitochondrial pyruvate carrier 2
NM_015415.3	NP_056230.1	mitochondrial pyruvate carrier 2
XM_006711266.3	XP_006711329.1	mitochondrial pyruvate carrier 2 isoform X1
NM_001143674.4	NP_001137146.1	mitochondrial pyruvate carrier 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Mpc2	NP_081706.1
Magnaporthe oryzae (rice blast fungus)	MGG_02668	XP_003721106.1
Homo sapiens (human)	MPC2	NP_001137146.1
	BRP44	XP_001091697.1
Drosophila melanogaster (fruit fly)	CG9396	NP_649912.1
Schizosaccharomyces pombe (fission yeast)	SPAC24B11.09	NP_592846.1
Neurospora crassa	NCU03155	XP_964561.1
Oryza sativa (rice)	Os08g0344300	NP_001061597.1
Xenopus tropicalis (tropical clawed frog)	mpc2	NP_001016695.1
Bos taurus (cattle)	BRP44	NP_001180050.1
Gallus gallus (chicken)	BRP44	NP_001265053.1
Danio rerio (zebrafish)	mpc2	NP_997757.1
Drosophila melanogaster (fruit fly)	CG9399	NP_001163571.1
Arabidopsis thaliana (thale cress)	AT4G22310	NP_193962.1
Pan troglodytes (chimpanzee)	BRP44	XP_001174837.1
Oryza sativa (rice)	Os07g0449100	NP_001059546.1
Canis lupus familiaris (dog)	MPC2	XP_537209.1
Rattus norvegicus (Norway rat)	Mpc2	NP_001071111.1
Kluyveromyces lactis	KLLA0A05500g	XP_451243.1
Eremothecium gossypii	AGOS_AEL210C	NP_984651.1

Gene Ontology
Bibliography

Related articles in PubMed

A mathematical model predicting host mitochondrial pyruvate transporter activity to be a critical regulator of Mycobacterium tuberculosis pathogenicity.
Mehrotra P, Rao KVS, Chatterjee S
Bio Systems1551-9(2017 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results indicate mitochondrial pyruvate transporter (MPC) to be the key regulatory junction perturbed by virulent strains of Mycobacterium tuberculosis leading to alteration of mitochondrial metabolic flux and regulation of acetyl-CoA formation.
Title: A mathematical model predicting host mitochondrial pyruvate transporter activity to be a critical regulator of Mycobacterium tuberculosis pathogenicity.

a significant association between MPC2 variant rs10489202 and Schizophrenia susceptibility in Han Chinese (Meta-Analysis)
Title: Association of NKAPL, TSPAN18, and MPC2 gene variants with schizophrenia based on new data and a meta-analysis in Han Chinese.

Our study indicates that MPC1 and MPC2 expressions are of prognostic values in PCAs and that positive expression of MPC1 or MPC2 is a predictor of favorable outcome.
Title: MPC1 and MPC2 expressions are associated with favorable clinical outcomes in prostate cancer.

These results reveal a novel post-translational regulation of MPC1 by Sirt3, which is important for its activity and colon cancer cell growth.
Title: Sirt3 binds to and deacetylates mitochondrial pyruvate carrier 1 to enhance its activity.

Tumor cells expressing MPC1 and MPC2 display increased mitochondrial pyruvate oxidation, with no changes in cell growth in adherent culture.
Title: A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth.

The following MPC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MPC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu11418	NM_001143674.4 Latest version!	Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11418	NM_015415.3 Latest version!	Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11418	XM_006711266.3 Latest version!	Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu11418	XM_006711266.2	Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11418	NM_001143674.3	Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MPC2 ( NM_001143674.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001137146.1 Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu11418
Clone ID Related Accession (Same CDS sequence)	XM_006711266.2 , NM_001143674.3 , NM_015415.3 , XM_006711266.3 , NM_001143674.4
Accession Version	NM_001143674.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	mitochondrial pyruvate carrier 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from KF455056.1, AL035304.1 and Z97876.1. On Jan 17, 2014 this sequence version replaced NM_001143674.2. Transcript Variant: This variant (1) encodes a functional protein. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL035304.1, BG720767.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCGGCCG CCGGTGCCCG AGGCCTGCGG GCCACCTACC ACCGGCTCCT CGATAAAGTG 
GAGCTGATGC TGCCCGAGAA ATTGAGGCCG TTGTACAACC ATCCAGCAGG TCCCAGAACA 
GTTTTCTTCT GGGCTCCAAT TATGAAATGG GGGTTGGTGT GTGCTGGATT GGCTGATATG 
GCCAGACCTG CAGAAAAACT TAGCACAGCT CAATCTGCTG TTTTGATGGC TACAGGGTTT 
ATTTGGTCAA GATACTCACT TGTAATTATT CCAAAAAATT GGAGTCTGTT TGCTGTTAAT 
TTCTTTGTGG GGGCAGCAGG AGCCTCTCAG CTTTTTCGTA TTTGGAGATA TAACCAAGAA 
CTAAAAGCTA AAGCACACAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001137146.1
CDS	189..572
Translation	MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQELKAKAHK

Target ORF information:

RefSeq Version	NM_001143674.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001143674.3

ORF Insert Sequence:

ATGTCGGCCG CCGGTGCCCG AGGCCTGCGG GCCACCTACC ACCGGCTCCT CGATAAAGTG 
GAGCTGATGC TGCCCGAGAA ATTGAGGCCG TTGTACAACC ATCCAGCAGG TCCCAGAACA 
GTTTTCTTCT GGGCTCCAAT TATGAAATGG GGGTTGGTGT GTGCTGGATT GGCTGATATG 
GCCAGACCTG CAGAAAAACT TAGCACAGCT CAATCTGCTG TTTTGATGGC TACAGGGTTT 
ATTTGGTCAA GATACTCACT TGTAATTATT CCAAAAAATT GGAGTCTGTT TGCTGTTAAT 
TTCTTTGTGG GGGCAGCAGG AGCCTCTCAG CTTTTTCGTA TTTGGAGATA TAACCAAGAA 
CTAAAAGCTA AAGCACACAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MPC2 ( NM_015415.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056230.1 Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11418
Clone ID Related Accession (Same CDS sequence)	XM_006711266.2 , NM_001143674.3 , NM_015415.3 , XM_006711266.3 , NM_001143674.4
Accession Version	NM_015415.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	mitochondrial pyruvate carrier 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from KF455056.1, AL554033.3 and Z97876.1. On Mar 26, 2011 this sequence version replaced NM_015415.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL554033.3, ERR279865.1488.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCGGCCG CCGGTGCCCG AGGCCTGCGG GCCACCTACC ACCGGCTCCT CGATAAAGTG 
GAGCTGATGC TGCCCGAGAA ATTGAGGCCG TTGTACAACC ATCCAGCAGG TCCCAGAACA 
GTTTTCTTCT GGGCTCCAAT TATGAAATGG GGGTTGGTGT GTGCTGGATT GGCTGATATG 
GCCAGACCTG CAGAAAAACT TAGCACAGCT CAATCTGCTG TTTTGATGGC TACAGGGTTT 
ATTTGGTCAA GATACTCACT TGTAATTATT CCAAAAAATT GGAGTCTGTT TGCTGTTAAT 
TTCTTTGTGG GGGCAGCAGG AGCCTCTCAG CTTTTTCGTA TTTGGAGATA TAACCAAGAA 
CTAAAAGCTA AAGCACACAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056230.1
CDS	123..506
Translation	MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQELKAKAHK

Target ORF information:

RefSeq Version	NM_015415.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015415.3

ORF Insert Sequence:

ATGTCGGCCG CCGGTGCCCG AGGCCTGCGG GCCACCTACC ACCGGCTCCT CGATAAAGTG 
GAGCTGATGC TGCCCGAGAA ATTGAGGCCG TTGTACAACC ATCCAGCAGG TCCCAGAACA 
GTTTTCTTCT GGGCTCCAAT TATGAAATGG GGGTTGGTGT GTGCTGGATT GGCTGATATG 
GCCAGACCTG CAGAAAAACT TAGCACAGCT CAATCTGCTG TTTTGATGGC TACAGGGTTT 
ATTTGGTCAA GATACTCACT TGTAATTATT CCAAAAAATT GGAGTCTGTT TGCTGTTAAT 
TTCTTTGTGG GGGCAGCAGG AGCCTCTCAG CTTTTTCGTA TTTGGAGATA TAACCAAGAA 
CTAAAAGCTA AAGCACACAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MPC2 ( NM_001143674.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001137146.1 Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu11418
Clone ID Related Accession (Same CDS sequence)	XM_006711266.2 , NM_001143674.3 , NM_015415.3 , XM_006711266.3 , NM_001143674.4
Accession Version	NM_001143674.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	mitochondrial pyruvate carrier 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from KF455056.1, AL035304.1 and Z97876.1. On Nov 22, 2018 this sequence version replaced NM_001143674.3. Transcript Variant: This variant (1) encodes a functional protein. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.374384.1, SRR5189667.392642.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000271373.9/ ENSP00000271373.4 RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGGCCG CCGGTGCCCG AGGCCTGCGG GCCACCTACC ACCGGCTCCT CGATAAAGTG 
GAGCTGATGC TGCCCGAGAA ATTGAGGCCG TTGTACAACC ATCCAGCAGG TCCCAGAACA 
GTTTTCTTCT GGGCTCCAAT TATGAAATGG GGGTTGGTGT GTGCTGGATT GGCTGATATG 
GCCAGACCTG CAGAAAAACT TAGCACAGCT CAATCTGCTG TTTTGATGGC TACAGGGTTT 
ATTTGGTCAA GATACTCACT TGTAATTATT CCAAAAAATT GGAGTCTGTT TGCTGTTAAT 
TTCTTTGTGG GGGCAGCAGG AGCCTCTCAG CTTTTTCGTA TTTGGAGATA TAACCAAGAA 
CTAAAAGCTA AAGCACACAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001137146.1
CDS	192..575
Translation	MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQELKAKAHK

Target ORF information:

RefSeq Version	NM_001143674.4
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001143674.4

ORF Insert Sequence:

ATGTCGGCCG CCGGTGCCCG AGGCCTGCGG GCCACCTACC ACCGGCTCCT CGATAAAGTG 
GAGCTGATGC TGCCCGAGAA ATTGAGGCCG TTGTACAACC ATCCAGCAGG TCCCAGAACA 
GTTTTCTTCT GGGCTCCAAT TATGAAATGG GGGTTGGTGT GTGCTGGATT GGCTGATATG 
GCCAGACCTG CAGAAAAACT TAGCACAGCT CAATCTGCTG TTTTGATGGC TACAGGGTTT 
ATTTGGTCAA GATACTCACT TGTAATTATT CCAAAAAATT GGAGTCTGTT TGCTGTTAAT 
TTCTTTGTGG GGGCAGCAGG AGCCTCTCAG CTTTTTCGTA TTTGGAGATA TAACCAAGAA 
CTAAAAGCTA AAGCACACAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MPC2 ( XM_006711266.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006711329.1 Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu11418
Clone ID Related Accession (Same CDS sequence)	XM_006711266.2 , NM_001143674.3 , NM_015415.3 , XM_006711266.3 , NM_001143674.4
Accession Version	XM_006711266.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	mitochondrial pyruvate carrier 2 isoform X1
Comment

ATGTCGGCCG CCGGTGCCCG AGGCCTGCGG GCCACCTACC ACCGGCTCCT CGATAAAGTG 
GAGCTGATGC TGCCCGAGAA ATTGAGGCCG TTGTACAACC ATCCAGCAGG TCCCAGAACA 
GTTTTCTTCT GGGCTCCAAT TATGAAATGG GGGTTGGTGT GTGCTGGATT GGCTGATATG 
GCCAGACCTG CAGAAAAACT TAGCACAGCT CAATCTGCTG TTTTGATGGC TACAGGGTTT 
ATTTGGTCAA GATACTCACT TGTAATTATT CCAAAAAATT GGAGTCTGTT TGCTGTTAAT 
TTCTTTGTGG GGGCAGCAGG AGCCTCTCAG CTTTTTCGTA TTTGGAGATA TAACCAAGAA 
CTAAAAGCTA AAGCACACAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006711329.1
Translation	MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQELKAKAHK

Target ORF information:

RefSeq Version	XM_006711266.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006711266.2

ORF Insert Sequence:

ATGTCGGCCG CCGGTGCCCG AGGCCTGCGG GCCACCTACC ACCGGCTCCT CGATAAAGTG 
GAGCTGATGC TGCCCGAGAA ATTGAGGCCG TTGTACAACC ATCCAGCAGG TCCCAGAACA 
GTTTTCTTCT GGGCTCCAAT TATGAAATGG GGGTTGGTGT GTGCTGGATT GGCTGATATG 
GCCAGACCTG CAGAAAAACT TAGCACAGCT CAATCTGCTG TTTTGATGGC TACAGGGTTT 
ATTTGGTCAA GATACTCACT TGTAATTATT CCAAAAAATT GGAGTCTGTT TGCTGTTAAT 
TTCTTTGTGG GGGCAGCAGG AGCCTCTCAG CTTTTTCGTA TTTGGAGATA TAACCAAGAA 
CTAAAAGCTA AAGCACACAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MPC2 ( XM_006711266.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006711329.1 Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu11418
Clone ID Related Accession (Same CDS sequence)	XM_006711266.2 , NM_001143674.3 , NM_015415.3 , XM_006711266.3 , NM_001143674.4
Accession Version	XM_006711266.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mitochondrial pyruvate carrier 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006711266.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGGCCG CCGGTGCCCG AGGCCTGCGG GCCACCTACC ACCGGCTCCT CGATAAAGTG 
GAGCTGATGC TGCCCGAGAA ATTGAGGCCG TTGTACAACC ATCCAGCAGG TCCCAGAACA 
GTTTTCTTCT GGGCTCCAAT TATGAAATGG GGGTTGGTGT GTGCTGGATT GGCTGATATG 
GCCAGACCTG CAGAAAAACT TAGCACAGCT CAATCTGCTG TTTTGATGGC TACAGGGTTT 
ATTTGGTCAA GATACTCACT TGTAATTATT CCAAAAAATT GGAGTCTGTT TGCTGTTAAT 
TTCTTTGTGG GGGCAGCAGG AGCCTCTCAG CTTTTTCGTA TTTGGAGATA TAACCAAGAA 
CTAAAAGCTA AAGCACACAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006711329.1
CDS	319..702
Translation	MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQELKAKAHK

Target ORF information:

RefSeq Version	XM_006711266.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial pyruvate carrier 2 (MPC2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006711266.3

ORF Insert Sequence:

ATGTCGGCCG CCGGTGCCCG AGGCCTGCGG GCCACCTACC ACCGGCTCCT CGATAAAGTG 
GAGCTGATGC TGCCCGAGAA ATTGAGGCCG TTGTACAACC ATCCAGCAGG TCCCAGAACA 
GTTTTCTTCT GGGCTCCAAT TATGAAATGG GGGTTGGTGT GTGCTGGATT GGCTGATATG 
GCCAGACCTG CAGAAAAACT TAGCACAGCT CAATCTGCTG TTTTGATGGC TACAGGGTTT 
ATTTGGTCAA GATACTCACT TGTAATTATT CCAAAAAATT GGAGTCTGTT TGCTGTTAAT 
TTCTTTGTGG GGGCAGCAGG AGCCTCTCAG CTTTTTCGTA TTTGGAGATA TAACCAAGAA 
CTAAAAGCTA AAGCACACAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A mathematical model predicting host mitochondrial pyruvate transporter activity to be a critical regulator of Mycobacterium tuberculosis pathogenicity.
Bio Systems1551-9(2017 May)
Mehrotra P,Rao KVS,Chatterjee S

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MPC2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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