dx cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

we observed that Dx together with Hrp48 can regulate Notch signaling in an Sxl-independent manner. In addition, Dx and Hrp48 displayed a synergistic effect on caspase-mediated cell death. Our results suggest that Dx and Hrp48 together negatively regulate Notch signaling in Drosophila melanogaster.
Title: Regulation of Notch Signaling by the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex in

Study identified a network of competing endocytic routes mediated by Su(dx) and Dx that positively and negatively regulate N activation; have distinct requirements for ligands, membrane sterol, and endosomal trafficking components; and have different temperature sensitivities.
Title: Compensatory flux changes within an endocytic trafficking network maintain thermal robustness of Notch signaling.

It was shown that Shrub plays a pivotal rate-limiting step in late endosomal ligand-independent Notch activation, depending on the Deltex-dependent ubiquitinylation state of the receptor.
Title: Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal.

Dx-mediated Notch receptor (N) signaling was activated in an endocytic compartment distinct from that in which canonical N signaling is activated, suggesting that N signaling can be activated in 2 different compartments during N's endocytic trafficking.
Title: Roles of Drosophila deltex in Notch receptor endocytic trafficking and activation.

Study shows that Deltex effects require endocytic trafficking by HOPS and AP-3 complexes; Deltex shunts Notch into an endocytic pathway with two possible endpoints.
Title: Drosophila HOPS and AP-3 complex genes are required for a Deltex-regulated activation of notch in the endosomal trafficking pathway.