crybb3 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	crybb3
Entrez Gene ID	553184
Full Name	crystallin, beta B3
General protein information	Preferred Names crystallin, beta B3 Names beta-crystallin B3 beta B3-crystallin
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001018130.1	NP_001018140.1	beta-crystallin B3

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	crybb3	NP_001018140.1
Xenopus tropicalis (tropical clawed frog)	crybb3	XP_002932114.1
Pan troglodytes (chimpanzee)	CRYBB3	XP_001171490.1
Canis lupus familiaris (dog)	CRYBB3	XP_003433442.1
Rattus norvegicus (Norway rat)	Crybb3	NP_113878.1
Gallus gallus (chicken)	CRYBB3	NP_990522.1
	CRYBB3	NP_001116372.1
Mus musculus (house mouse)	Crybb3	NP_067327.1
Homo sapiens (human)	CRYBB3	NP_004067.1
Bos taurus (cattle)	CRYBB3	NP_776952.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution and Expression of Paxillin Genes in Teleost Fish.
Jacob AE, Turner CE, Amack JD
PloS one11(11)e0165266(2016)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Lens defects in Astyanax mexicanus Cavefish: evolution of crystallins and a role for alphaA-crystallin.
Hinaux H, Blin M, Fumey J, Legendre L, Heuz? A, Casane D, R?taux S
Developmental neurobiology75(5)505-21(2015 May)

Changes in zebrafish (Danio rerio) lens crystallin content during development.
Wages P, Horwitz J, Ding L, Corbin RW, Posner M
Molecular vision19408-17(2013)

The zebrafish lens proteome during development and aging.
Greiling TM, Houck SA, Clark JI
Molecular vision152313-25(2009 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following crybb3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the crybb3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa35554	NM_001018130.1 Latest version!	Danio rerio crystallin, beta B3 (crybb3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

crybb3 ( NM_001018130.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001018140.1 Danio rerio crystallin, beta B3 (crybb3), mRNA.

Price & Availability↑

CloneID	ODa35554
Clone ID Related Accession (Same CDS sequence)	NM_001018130.1
Accession Version	NM_001018130.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	beta-crystallin B3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ000468.1. On Sep 23, 2011 this sequence version replaced XM_001338607.4. ##Evidence-Data-START## Transcript exon combination :: DQ000468.1, EH449613.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGTCGGATC AGCAGGGAGT CCCAGATCAG CAGGTGGCTG GGAAAAGCCA AGGAGGAGCA 
GGAGCGATCT ACAAGGTCTC ACTGTATGAA TTCGAGAACT TCCGTGGGAA AAAGCTGGAG 
CTGTCAGCAG AATGCAAGGA CCTGATTGAG AAGAACTTGG AGAAAGTGGG ATCAATCATA 
GTTGAGTCCG GCCCATGGGT GGGCTTTGAG CAGAAGGGCT TTTTGGGAGA GCAGTTTGTC 
CTGGAGAAGG GAGAATACCC CCGCTGGAGC ACCTGGACCA ACAGCCAGAA CAGCTTTTGC 
CTGCTGTCCA TCAGACCCCT ACGTGTGGAT AGCGCAGACC ACAAACTACA TCTGTTTGAG 
AACTGCAGCT TCGCCGGGAG AAAGATGGAA ATCGTGGACG ATGACATTCC CAGTTTGTGG 
GTTCATGGCT TCCAGGATCG TGTGGCCAGT GCGAAAGCTG TCAACGGAAC ATGGGTGGGC 
TACATGTACC CTGGCTACCG CGGCCGGCAG TTTGTGTTTG AACATGGCGA CTACAAACAC 
TGGAACGACT GGGGAGCCAC AGAACCACAG CTGCAGTCCG TCCGGCGTGT GCGGGATATG 
CAGTGGCACA AACGGGGCTG TTTCACCGTT CCCACCCCCG ACCCAGCTCC CAAACCCAAC 
CCAAACCCCA ATCCCAATCC AAACCCCAAT CCAAACCCAA ACCCCAATCC CAATCCTGCA 
CCCAATCCAG CCCCAGCTCC CGCTCCCCCT GCCCCATCCG CCACAGCTGC CAGCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001018140.1
CDS	107..886
Translation	MSDQQGVPDQQVAGKSQGGAGAIYKVSLYEFENFRGKKLELSAECKDLIEKNLEKVGSIIVESGPWVGFEQKGFLGEQFVLEKGEYPRWSTWTNSQNSFCLLSIRPLRVDSADHKLHLFENCSFAGRKMEIVDDDIPSLWVHGFQDRVASAKAVNGTWVGYMYPGYRGRQFVFEHGDYKHWNDWGATEPQLQSVRRVRDMQWHKRGCFTVPTPDPAPKPNPNPNPNPNPNPNPNPNPNPAPNPAPAPAPPAPSATAASS

Target ORF information:

RefSeq Version	NM_001018130.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio crystallin, beta B3 (crybb3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001018130.1

ORF Insert Sequence:

ATGTCGGATC AGCAGGGAGT CCCAGATCAG CAGGTGGCTG GGAAAAGCCA AGGAGGAGCA 
GGAGCGATCT ACAAGGTCTC ACTGTATGAA TTCGAGAACT TCCGTGGGAA AAAGCTGGAG 
CTGTCAGCAG AATGCAAGGA CCTGATTGAG AAGAACTTGG AGAAAGTGGG ATCAATCATA 
GTTGAGTCCG GCCCATGGGT GGGCTTTGAG CAGAAGGGCT TTTTGGGAGA GCAGTTTGTC 
CTGGAGAAGG GAGAATACCC CCGCTGGAGC ACCTGGACCA ACAGCCAGAA CAGCTTTTGC 
CTGCTGTCCA TCAGACCCCT ACGTGTGGAT AGCGCAGACC ACAAACTACA TCTGTTTGAG 
AACTGCAGCT TCGCCGGGAG AAAGATGGAA ATCGTGGACG ATGACATTCC CAGTTTGTGG 
GTTCATGGCT TCCAGGATCG TGTGGCCAGT GCGAAAGCTG TCAACGGAAC ATGGGTGGGC 
TACATGTACC CTGGCTACCG CGGCCGGCAG TTTGTGTTTG AACATGGCGA CTACAAACAC 
TGGAACGACT GGGGAGCCAC AGAACCACAG CTGCAGTCCG TCCGGCGTGT GCGGGATATG 
CAGTGGCACA AACGGGGCTG TTTCACCGTT CCCACCCCCG ACCCAGCTCC CAAACCCAAC 
CCAAACCCCA ATCCCAATCC AAACCCCAAT CCAAACCCAA ACCCCAATCC CAATCCTGCA 
CCCAATCCAG CCCCAGCTCC CGCTCCCCCT GCCCCATCCG CCACAGCTGC CAGCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution and Expression of Paxillin Genes in Teleost Fish.
PloS one11(11)e0165266(2016)
Jacob AE,Turner CE,Amack JD

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Lens defects in Astyanax mexicanus Cavefish: evolution of crystallins and a role for alphaA-crystallin.
Developmental neurobiology75(5)505-21(2015 May)
Hinaux H,Blin M,Fumey J,Legendre L,Heuz? A,Casane D,R?taux S

Changes in zebrafish (Danio rerio) lens crystallin content during development.
Molecular vision19408-17(2013)
Wages P,Horwitz J,Ding L,Corbin RW,Posner M

The zebrafish lens proteome during development and aging.
Molecular vision152313-25(2009 Nov)
Greiling TM,Houck SA,Clark JI