sepsecs cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	sepsecs
Entrez Gene ID	393123
Full Name	Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
Synonyms	sla/lpl,zgc:55980
General protein information	Preferred Names Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase Names O-phosphoseryl-tRNA(Sec) selenium transferase UGA suppressor tRNA-associated protein homolog sec synthase selenocysteine synthase selenocysteinyl-tRNA(Sec) synthase sep-tRNA:Sec-tRNA synthase soluble liver antigen/liver pancreas antigen, like
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_200154.1	NP_956448.1	O-phosphoseryl-tRNA(Sec) selenium transferase

Pathways from BioSystems

Homologies

Homo sapiens (human)	SEPSECS	NP_058651.3
	SLA/LP	XP_001082141.2
Mus musculus (house mouse)	Sepsecs	NP_766078.1
Rattus norvegicus (Norway rat)	Sepsecs	NP_001121759.1
Danio rerio (zebrafish)	sepsecs	NP_956448.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003527	XP_313270.4
Canis lupus familiaris (dog)	SEPSECS	XP_545970.3
Bos taurus (cattle)	SEPSECS	XP_002688221.2
Drosophila melanogaster (fruit fly)	CG1427	NP_649556.3
Xenopus tropicalis (tropical clawed frog)	sepsecs	NP_001004947.2
Pan troglodytes (chimpanzee)	SEPSECS	XP_517129.2
Gallus gallus (chicken)	SEPSECS	NP_001026329.1
Caenorhabditis elegans (roundworm)	secs-1	NP_001129887.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Sex-specific transcriptional responses of the zebrafish (Danio rerio) brain selenoproteome to acute sodium selenite supplementation.
Benner MJ, Settles ML, Murdoch GK, Hardy RW, Robison BD
Physiological genomics45(15)653-66(2013 Aug)

Zebrafish fin immune responses during high mortality infections with viral haemorrhagic septicemia rhabdovirus. A proteomic and transcriptomic approach.
Encinas P, Rodriguez-Milla MA, Novoa B, Estepa A, Figueras A, Coll J
BMC genomics11518(2010 Sep)

Characterization of human gene encoding SLA/LP autoantigen and its conserved homologs in mouse, fish, fly, and worm.
Wang CX, Teufel A, Cheruti U, Gr?tzinger J, Galle PR, Lohse AW, Herkel J
World journal of gastroenterology12(6)902-7(2006 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following sepsecs gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sepsecs cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01273	NM_200154.1 Latest version!	Danio rerio Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase (sepsecs), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

sepsecs ( NM_200154.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_956448.1 Danio rerio Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase (sepsecs), mRNA.

Price & Availability↑

CloneID	ODa01273
Clone ID Related Accession (Same CDS sequence)	NM_200154.1
Accession Version	NM_200154.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	O-phosphoseryl-tRNA(Sec) selenium transferase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC044561.1. On Jul 6, 2005 this sequence version replaced XM_697135.1. ##Evidence-Data-START## Transcript exon combination :: BC044561.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGAACAGCG AGAACTTCAG GCTGAGTGAG AAGCTCGTGT CCGCCTCATA TGTGCGGCAG 
GGTCTGGACG CGCGCCGCGG GCACGAGCAG CTCATCCGAC GGCTGTTAGA CCAGGGTAAA 
TGTCCAGAGG AGGGCTGGAG CGAAAGCACC ATTGAGCTCT TCCTGAATGA ACTGGCTGTC 
ATGGACAGCA ACAACTTCTT AGGGAACTGT GGTGTGGGAG AGAGAGAAGG ACGAGTGGCA 
TCCAGCCTGG TGGCCAGGAG ACATTACAGG CTGATCCATG GCATCGGTCG GTCGGGTGAC 
ATCGCAGCTG TTCAGCCGAA AGCCGCCGGT TCGAGTCTTC TGAATAAAAT CACTAATTCA 
GTAGTTCTGG ACGTGCTGAA GCTCACAGGC GTCCGCAGCG TGTCCTCGTG TTTCGTGGTG 
CCGATGGCCA CAGGAATGAG CCTCACGCTG TGTTTCCTCA CGCTCAGACA CAGGAGACCA 
AAAGCACGTT ATATTCTCTG GCCTCGCATT GACCAGAAGT CCTGTTTCAA GTCTATGGTG 
ACCGCTGGCT TTGAGCCTGT GGTGATCGAG AATGTTCTGG AAGGAGACGA GCTGAGGACG 
AATCTGGAGG AAGTGGAGAG GAAGATTGAG GAGTTCGGGG CTGAAAACAC CCTGTGTGTT 
CATTCCACCA CTTCCTGTTT CGCACCGCGT GTCCCTGACA GGTTAGAGGA ACTCTCGGTT 
TTATGTGCCA AGCATGATAT TCCTCACATA GTCAATAACG CTTATGGAGT GCAGCCGTCC 
AAATGTATGC ACCTTATTCA GCAGGGGGCT CGGGTAGGGA GAATCGATGC CTTTGTCCAA 
AGTCTGGATA AAAACTTCGT GGTCCCAGTC GGCGGTGCAA TTATCGCTGG GTTTGATGAA 
AACTTCATTC AGGAGATCAG TAAGATCTAC CCAGGTCGAG CGTCTGCGTC TCCATCTCTA 
GATGTCCTCA TCACACTGCT CACACTGGGA GCAAACGGAT ACAAGAAACT CCTGGCGGAC 
AGAAAGGAGC TGTACGGGCA TCTGGCGCAG GAGCTGAGCG CTTTAGCCGC GAGACACGGA 
GAGAGACTGC TGAAAACACC ACACAACCCC ATATCACTGG CGATGTCCCT GAACCATCTG 
GAAGCCCACA GTAGCTCTGC AGTCACTCAG CTGGGCTCCA TGCTCTTCAC CAGGCAGGTT 
TCTGGAGCCA GGGTGGTCCC GTTAGGAGTG CAGCAGACTG TGAGTGGACA CACCTTCAGT 
GGCTTTATGT CCCACTCCGA GGCCTACCCC TGCCCATACC TCAACGCTGC GTCTGCTATC 
GGAATAACCA AAGGAGACGT CACCGTGTGC ATGAAGAGAC TGGGGAAATG CCTGAAAATC 
CTGAAGAAAG AGAAAAGTGA CCCTGCAGAT CTGGAGGCGG AAGATGGAGA GCTGGAGGAG 
AGCCCACAGA GATCCACAGA GTTGCGTGTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_956448.1
CDS	141..1613
Translation	MNSENFRLSEKLVSASYVRQGLDARRGHEQLIRRLLDQGKCPEEGWSESTIELFLNELAVMDSNNFLGNCGVGEREGRVASSLVARRHYRLIHGIGRSGDIAAVQPKAAGSSLLNKITNSVVLDVLKLTGVRSVSSCFVVPMATGMSLTLCFLTLRHRRPKARYILWPRIDQKSCFKSMVTAGFEPVVIENVLEGDELRTNLEEVERKIEEFGAENTLCVHSTTSCFAPRVPDRLEELSVLCAKHDIPHIVNNAYGVQPSKCMHLIQQGARVGRIDAFVQSLDKNFVVPVGGAIIAGFDENFIQEISKIYPGRASASPSLDVLITLLTLGANGYKKLLADRKELYGHLAQELSALAARHGERLLKTPHNPISLAMSLNHLEAHSSSAVTQLGSMLFTRQVSGARVVPLGVQQTVSGHTFSGFMSHSEAYPCPYLNAASAIGITKGDVTVCMKRLGKCLKILKKEKSDPADLEAEDGELEESPQRSTELRV

Target ORF information:

RefSeq Version	NM_200154.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase (sepsecs), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_200154.1

ORF Insert Sequence:

ATGAACAGCG AGAACTTCAG GCTGAGTGAG AAGCTCGTGT CCGCCTCATA TGTGCGGCAG 
GGTCTGGACG CGCGCCGCGG GCACGAGCAG CTCATCCGAC GGCTGTTAGA CCAGGGTAAA 
TGTCCAGAGG AGGGCTGGAG CGAAAGCACC ATTGAGCTCT TCCTGAATGA ACTGGCTGTC 
ATGGACAGCA ACAACTTCTT AGGGAACTGT GGTGTGGGAG AGAGAGAAGG ACGAGTGGCA 
TCCAGCCTGG TGGCCAGGAG ACATTACAGG CTGATCCATG GCATCGGTCG GTCGGGTGAC 
ATCGCAGCTG TTCAGCCGAA AGCCGCCGGT TCGAGTCTTC TGAATAAAAT CACTAATTCA 
GTAGTTCTGG ACGTGCTGAA GCTCACAGGC GTCCGCAGCG TGTCCTCGTG TTTCGTGGTG 
CCGATGGCCA CAGGAATGAG CCTCACGCTG TGTTTCCTCA CGCTCAGACA CAGGAGACCA 
AAAGCACGTT ATATTCTCTG GCCTCGCATT GACCAGAAGT CCTGTTTCAA GTCTATGGTG 
ACCGCTGGCT TTGAGCCTGT GGTGATCGAG AATGTTCTGG AAGGAGACGA GCTGAGGACG 
AATCTGGAGG AAGTGGAGAG GAAGATTGAG GAGTTCGGGG CTGAAAACAC CCTGTGTGTT 
CATTCCACCA CTTCCTGTTT CGCACCGCGT GTCCCTGACA GGTTAGAGGA ACTCTCGGTT 
TTATGTGCCA AGCATGATAT TCCTCACATA GTCAATAACG CTTATGGAGT GCAGCCGTCC 
AAATGTATGC ACCTTATTCA GCAGGGGGCT CGGGTAGGGA GAATCGATGC CTTTGTCCAA 
AGTCTGGATA AAAACTTCGT GGTCCCAGTC GGCGGTGCAA TTATCGCTGG GTTTGATGAA 
AACTTCATTC AGGAGATCAG TAAGATCTAC CCAGGTCGAG CGTCTGCGTC TCCATCTCTA 
GATGTCCTCA TCACACTGCT CACACTGGGA GCAAACGGAT ACAAGAAACT CCTGGCGGAC 
AGAAAGGAGC TGTACGGGCA TCTGGCGCAG GAGCTGAGCG CTTTAGCCGC GAGACACGGA 
GAGAGACTGC TGAAAACACC ACACAACCCC ATATCACTGG CGATGTCCCT GAACCATCTG 
GAAGCCCACA GTAGCTCTGC AGTCACTCAG CTGGGCTCCA TGCTCTTCAC CAGGCAGGTT 
TCTGGAGCCA GGGTGGTCCC GTTAGGAGTG CAGCAGACTG TGAGTGGACA CACCTTCAGT 
GGCTTTATGT CCCACTCCGA GGCCTACCCC TGCCCATACC TCAACGCTGC GTCTGCTATC 
GGAATAACCA AAGGAGACGT CACCGTGTGC ATGAAGAGAC TGGGGAAATG CCTGAAAATC 
CTGAAGAAAG AGAAAAGTGA CCCTGCAGAT CTGGAGGCGG AAGATGGAGA GCTGGAGGAG 
AGCCCACAGA GATCCACAGA GTTGCGTGTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Sex-specific transcriptional responses of the zebrafish (Danio rerio) brain selenoproteome to acute sodium selenite supplementation.
Physiological genomics45(15)653-66(2013 Aug)
Benner MJ,Settles ML,Murdoch GK,Hardy RW,Robison BD

Zebrafish fin immune responses during high mortality infections with viral haemorrhagic septicemia rhabdovirus. A proteomic and transcriptomic approach.
BMC genomics11518(2010 Sep)
Encinas P,Rodriguez-Milla MA,Novoa B,Estepa A,Figueras A,Coll J

Characterization of human gene encoding SLA/LP autoantigen and its conserved homologs in mouse, fish, fly, and worm.
World journal of gastroenterology12(6)902-7(2006 Feb)
Wang CX,Teufel A,Cheruti U,Gr?tzinger J,Galle PR,Lohse AW,Herkel J