kctd13 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	kctd13
Entrez Gene ID	100000647
Full Name	potassium channel tetramerization domain containing 13
Synonyms	zgc:153421
General protein information	Preferred Names potassium channel tetramerization domain containing 13 Names BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 BTB/POZ domain-containing protein KCTD13 potassium channel tetramerisation domain containing 13
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001077151.1	NP_001070619.1	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	KCTD13	NP_849194.1
Danio rerio (zebrafish)	kctd13	NP_001070619.1
Bos taurus (cattle)	KCTD13	NP_001033146.1
Mus musculus (house mouse)	Kctd13	NP_766335.1
Pan troglodytes (chimpanzee)	KCTD13	XP_510914.2
Rattus norvegicus (Norway rat)	Kctd13	NP_942031.1
Canis lupus familiaris (dog)	KCTD13	XP_547062.1

Gene Ontology
Bibliography

Related articles in PubMed

Kctd13 deletion reduces synaptic transmission via increased RhoA.
Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, L?pez-Garc?a IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM
Nature551(7679)227-231(2017 Nov)

The 16p11.2 homologs fam57ba and doc2a generate certain brain and body phenotypes.
McCammon JM, Blaker-Lee A, Chen X, Sive H
Human molecular genetics26(19)3699-3712(2017 Oct)

Validation of Protein Knockout in Mutant Zebrafish Lines Using In Vitro Translation Assays.
Carter BS, Cort?s-Campos C, Chen X, McCammon JM, Sive HL
Zebrafish14(1)73-76(2017 02)

Maternal exposure to the water soluble fraction of crude oil, lead and their mixture induces autism-like behavioral deficits in zebrafish (Danio rerio) larvae.
Wang Y, Zhong H, Wang C, Gao D, Zhou Y, Zuo Z
Ecotoxicology and environmental safety134P123-30(2016 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following kctd13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the kctd13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa02653	NM_001077151.1 Latest version!	Danio rerio potassium channel tetramerization domain containing 13 (kctd13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

kctd13 ( NM_001077151.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001070619.1 Danio rerio potassium channel tetramerization domain containing 13 (kctd13), mRNA.

Price & Availability↑

CloneID	ODa02653
Clone ID Related Accession (Same CDS sequence)	NM_001077151.1
Accession Version	NM_001077151.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Danio rerio(zebrafish)
Product	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122284.1. On Oct 11, 2006 this sequence version replaced XM_683988.1. ##Evidence-Data-START## Transcript exon combination :: BC122284.1, BC157374.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGTCTGCCG AGGCATCTGG TTCGTCTGGT GGGCATGCGG TGACTGTGTC CGGGTCTTCC 
CCGTCATCCT CCAGCCATGT TGGGGAAGAA AAGCCTGGCA GGAGTCTGGT GAGCAGCAAG 
TACGTGAAGC TCAATGTTGG CGGAACTCTC CACTACACCA CAGTCCAAAC GCTCAGCAAA 
GAAGACAGCC TGCTCAGGAG TATTTGTGAC GGGAGCACAG AGGTCAGCAT CGACTCTGAA 
GGCTGGGTGG TGTTGGACCG ATGCGGGAGA CACTTTTCCC TGGTGTTGAA CTTCCTGCGG 
GACGGGACAG TTCCTTTGCC AGATAGCACG AGGGAGCTGG AGGAGGTGTT GAAGGAGGCG 
CAATACTACA GACTTCAGGG TCTTGTGCAG CACTGCCTCT CCATATTACA GAAACGCAGA 
GATGTTTGCA GAGGTTGTCA CATTCCTATG ATAACTTCAG CCAAAGAGGA ACAGAGGATG 
ATAGCCACCT GTAGAAAGCC AGTGGTGAAA CTGCAGAATA ATAGAGGGAA CAATAAATAC 
TCCTATACCA GCAACTCTGA TGATAACCTC CTGAAGAACA TCGAGCTGTT CGATAAGCTG 
GGGCTGCGCT TTAACGGCCG GGTTCTGTTT ATTAAAGACG TGCTGGGAGA TGAGATTTGC 
TGCTGGTCTT TTTACGGCGA GGGACGCAAG ATTGCTGAAG TCTGCTGCAC CTCCATTGTT 
TATGCCACCG AGAAGAAGCA GACCAAAGTT GAGTTTCCAG AAGCTCGTAT ATTCGAGGAG 
ACGCTCAACA TTTTGATTTA TGAAAATGGG CGTGGCTCGG GAGGAATGGC CCTGCTGGAG 
TCTGGGGGCG TTTCTTCATC GGGTGCAGGC CAATCAGAGG AGGAAGGGGC GGGTGCAGGG 
GGCGGAGACA GGCGGGTGAG GCGGATCCAT GTGCGGAGGC ATATTATGCA TGACGAAAGG 
GGTCACGGAC AGCAGACTGT CTACAAAGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070619.1
CDS	196..1188
Translation	MSAEASGSSGGHAVTVSGSSPSSSSHVGEEKPGRSLVSSKYVKLNVGGTLHYTTVQTLSKEDSLLRSICDGSTEVSIDSEGWVVLDRCGRHFSLVLNFLRDGTVPLPDSTRELEEVLKEAQYYRLQGLVQHCLSILQKRRDVCRGCHIPMITSAKEEQRMIATCRKPVVKLQNNRGNNKYSYTSNSDDNLLKNIELFDKLGLRFNGRVLFIKDVLGDEICCWSFYGEGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYENGRGSGGMALLESGGVSSSGAGQSEEEGAGAGGGDRRVRRIHVRRHIMHDERGHGQQTVYKD

Target ORF information:

RefSeq Version	NM_001077151.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio potassium channel tetramerization domain containing 13 (kctd13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077151.1

ORF Insert Sequence:

ATGTCTGCCG AGGCATCTGG TTCGTCTGGT GGGCATGCGG TGACTGTGTC CGGGTCTTCC 
CCGTCATCCT CCAGCCATGT TGGGGAAGAA AAGCCTGGCA GGAGTCTGGT GAGCAGCAAG 
TACGTGAAGC TCAATGTTGG CGGAACTCTC CACTACACCA CAGTCCAAAC GCTCAGCAAA 
GAAGACAGCC TGCTCAGGAG TATTTGTGAC GGGAGCACAG AGGTCAGCAT CGACTCTGAA 
GGCTGGGTGG TGTTGGACCG ATGCGGGAGA CACTTTTCCC TGGTGTTGAA CTTCCTGCGG 
GACGGGACAG TTCCTTTGCC AGATAGCACG AGGGAGCTGG AGGAGGTGTT GAAGGAGGCG 
CAATACTACA GACTTCAGGG TCTTGTGCAG CACTGCCTCT CCATATTACA GAAACGCAGA 
GATGTTTGCA GAGGTTGTCA CATTCCTATG ATAACTTCAG CCAAAGAGGA ACAGAGGATG 
ATAGCCACCT GTAGAAAGCC AGTGGTGAAA CTGCAGAATA ATAGAGGGAA CAATAAATAC 
TCCTATACCA GCAACTCTGA TGATAACCTC CTGAAGAACA TCGAGCTGTT CGATAAGCTG 
GGGCTGCGCT TTAACGGCCG GGTTCTGTTT ATTAAAGACG TGCTGGGAGA TGAGATTTGC 
TGCTGGTCTT TTTACGGCGA GGGACGCAAG ATTGCTGAAG TCTGCTGCAC CTCCATTGTT 
TATGCCACCG AGAAGAAGCA GACCAAAGTT GAGTTTCCAG AAGCTCGTAT ATTCGAGGAG 
ACGCTCAACA TTTTGATTTA TGAAAATGGG CGTGGCTCGG GAGGAATGGC CCTGCTGGAG 
TCTGGGGGCG TTTCTTCATC GGGTGCAGGC CAATCAGAGG AGGAAGGGGC GGGTGCAGGG 
GGCGGAGACA GGCGGGTGAG GCGGATCCAT GTGCGGAGGC ATATTATGCA TGACGAAAGG 
GGTCACGGAC AGCAGACTGT CTACAAAGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Kctd13 deletion reduces synaptic transmission via increased RhoA.
Nature551(7679)227-231(2017 Nov)
Escamilla CO,Filonova I,Walker AK,Xuan ZX,Holehonnur R,Espinosa F,Liu S,Thyme SB,L?pez-Garc?a IA,Mendoza DB,Usui N,Ellegood J,Eisch AJ,Konopka G,Lerch JP,Schier AF,Speed HE,Powell CM

The 16p11.2 homologs fam57ba and doc2a generate certain brain and body phenotypes.
Human molecular genetics26(19)3699-3712(2017 Oct)
McCammon JM,Blaker-Lee A,Chen X,Sive H

Validation of Protein Knockout in Mutant Zebrafish Lines Using In Vitro Translation Assays.
Zebrafish14(1)73-76(2017 02)
Carter BS,Cort?s-Campos C,Chen X,McCammon JM,Sive HL

Maternal exposure to the water soluble fraction of crude oil, lead and their mixture induces autism-like behavioral deficits in zebrafish (Danio rerio) larvae.
Ecotoxicology and environmental safety134P123-30(2016 Dec)
Wang Y,Zhong H,Wang C,Gao D,Zhou Y,Zuo Z