STK10 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	STK10
Entrez Gene ID	526376
Full Name	serine/threonine kinase 10
General protein information	Preferred Names serine/threonine kinase 10 Names serine/threonine-protein kinase 10
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001192627.1	NP_001179556.1	serine/threonine-protein kinase 10

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	STK10	XP_546239.2
Bos taurus (cattle)	STK10	NP_001179556.1
Rattus norvegicus (Norway rat)	Stk10	NP_062079.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010551	XP_314524.4
Homo sapiens (human)	STK10	NP_005981.3
	STK10	XP_002804682.1
Gallus gallus (chicken)	STK10	XP_414529.4
Caenorhabditis elegans (roundworm)	gck-4	NP_510290.1
Pan troglodytes (chimpanzee)	STK10	XP_518098.4
Mus musculus (house mouse)	Stk10	NP_033314.2
Danio rerio (zebrafish)	stk10	NP_957427.1
Drosophila melanogaster (fruit fly)	slik	NP_001014549.1
Xenopus tropicalis (tropical clawed frog)	stk10	NP_001072623.1

Gene Ontology
Bibliography

Related articles in PubMed

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.
Belkina NV, Liu Y, Hao JJ, Karasuyama H, Shaw S
Proceedings of the National Academy of Sciences of the United States of America106(12)4707-12(2009 Mar)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites.
Pike AC, Rellos P, Niesen FH, Turnbull A, Oliver AW, Parker SA, Turk BE, Pearl LH, Knapp S
The EMBO journal27(4)704-14(2008 Feb)

Stk10, a new member of the polo-like kinase kinase family highly expressed in hematopoietic tissue.
Walter SA, Cutler RE Jr, Martinez R, Gishizky M, Hill RJ
The Journal of biological chemistry278(20)18221-8(2003 May)

Deficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytes.
Endo J, Toyama-Sorimachi N, Taya C, Kuramochi-Miyagawa S, Nagata K, Kuida K, Takashi T, Yonekawa H, Yoshizawa Y, Miyasaka N, Karasuyama H
FEBS letters468(2-3)234-8(2000 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following STK10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STK10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa00916	NM_001192627.1 Latest version!	Bos taurus serine/threonine kinase 10 (STK10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$510.30 $729.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

STK10 ( NM_001192627.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001179556.1 Bos taurus serine/threonine kinase 10 (STK10), mRNA.

Price & Availability↑

CloneID	OBa00916
Clone ID Related Accession (Same CDS sequence)	NM_001192627.1
Accession Version	NM_001192627.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2904bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Bos taurus(cattle)
Product	serine/threonine-protein kinase 10
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from NKLS02000020.1. On Jul 17, 2010 this sequence version replaced XM_604746.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR5571257.54532.1, SRR5571258.3618.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145412, SAMN03145413 [ECO:0000350] ##Evidence-Data-END##

ATGGCTTTCG CCAATTTCCG CCGCATCCTG CGCCTGTCTA CCTTCGAGAA GAGAAAGTCC 
CGCGAATATG AGCATGTCCG CCGGGACCTG GATCCCAACG AGGTGTGGGA GATCGTGGGC 
GAGCTGGGCG ACGGTGCCTT CGGCAAGGTT TACAAGGCCA AGAACAAGGA GACGGGTGCC 
CTGGCCGCGG CCAAAGTAAT CGAGACCAAC AGCGAGGAGG AGCTGGAAGA CTACATCGTG 
GAGATCGAGA TCCTGGCCAC CTGCGACCAC CCCTACATCG TGAAGCTCCT AGGCGCCTAC 
TACTATGACG GGAAGCTGTG GATTATGATC GAGTTCTGTC CTGGGGGAGC TGTGGATGCC 
ATCATGCTGG AGCTGGACAG AGGCCTCACT GAGCCCCAGA TTCAGGTGGT TTGCCGCCAG 
ATGCTGGAAG CCCTCACCTT CCTGCATGGC AAGAAGATCA TCCACCGGGA CCTGAAAGCC 
GGCAACGTGC TCATGACCCT CGAGGGGGAC ATCAGGCTGG CTGACTTCGG TGTGTCTGCC 
AAGAATCTGA AAACTTTGCA GAAGCGAGAT TCCTTCATAG GAACGCCTTA CTGGATGGCC 
CCCGAGGTGG TGATGTGTGA GACCATGAAG GACACCCCGT ACGACTACAA GGCAGACATC 
TGGTCGCTGG GCATCACGCT GATTGAGATG GCCCAGATCG AGCCCCCGCA CCACGAGCTC 
AACCCCATGC GGGTGCTGCT CAAGATCGCC AAGTCCGATC CTCCCACACT GCTCTCGCCC 
TCTAAGTGGT CTGCAGAGTT CCGAGATTTC CTGAAGACAG CCCTGGATAA GAACCCAGAG 
ACACGGCCCA GCGCTGCGCA GCTCCTGGAG CATCCCTTCG TCAGCAGCGT CACCAGCAAC 
AAGGCCCTGC GGGAGCTGGT GGCCGAGGCC AAGGCTGAAG TGATGGAGGA GATTGAAGAC 
GGCCGAGATG AGGGGGATGA GGAGGATGCG GTGGAGGCTG CCTCTCCTCT GGAGAACCAC 
ACTCGAGACT CCTCCGAGGT GAGTCAGCTG AGCATTGATG CGGACAAACT TCTCAAAGAA 
TCACCTTTCA CCCCACCACC TCCCAGCCAG CCTCAGGATG GTGCGAATGG GCCCAGCGAG 
CCCCCTGGGC ACGGGGCCCT CCCGGCCACC AGCCCCCTGG ATGTGGCCCC TGGAAACGAG 
AATGGCCAGG CGGTGCCTGT GCCCCTCCGG AAGTTCCGAC CAGTGTCCAT GGGTGCCAGA 
ATTCAGGTGT CCGAGGAGAA GCAAGCCGCT GACCAGGGTG GAGACCTCAG TCCAGCGGCC 
AGCAGGTCCC AGAAAGCAAG CCAGAGCCGT CCCAACAGCA GCGCCCTGGA GACCTTGCGC 
AGCGAGCTGA CCAATGGCAG TCTGGAGCTC CCCACCCCGG GGGCACAGAG CCTTTCCAAG 
AGGGACTCAG ATTGTGGCAG CGTCTCCACC TCTGGGAGCA CGGACTTCGG CACCTCCCTG 
TCAGCAGACA TGTCCGTGAA CAAGGAGTCG GGCTCTCTGT CCATCAAGGA CTCAAGGCTG 
CACAATAAGA CCCTGAAGAG GACACGCAAG TTTGTTGTGG ATGGCGTGGA GGTGAGCATT 
ACCACCTCCA AGATCATCAG CGAGGATGAG AAGAAGGACG AGGAGATGCG ATTCCTCAGG 
CGCCAGGAAC TCCGAGAGCT TCGGCTGCTC CAGAAAGAAG AACATCGGAA TCAAACCCAA 
CTGAGCAGCA AGCATGAGCT GCAGCTGGAG CAAATGCATA AGCGTTTTGA ACAAGAAATC 
AACGCCAAGA AGAAGTTCTT TGACATAGAG CTGGAGAACC TGGAGCGTCA GCAAAAGCAA 
CAAGTAGAGA AGATGGAGCA AGACCACGCG GTGCGCCGCC GGGAGGAGGC CAAGCGGATT 
CGCCTGGAGC AGGAGCGGGA CTATGCCAAG TTCCAGGAGC AGCTCAAGCT GATGAAGAAG 
GAGGTGAAGA ATGAGGTGGA GAAGCTCCCC CGGCAGCAGC GGAAGGAGAG CATGAAGCAG 
AAGATGGAGG AGCACACTCA GAAAAAGCAG CTTCTCGACC GGGACTTCCT GGCCAAGCAG 
AAGGAAGACC TGGAGCTGGC CATGAAGAGG ATCACGGCCG ACAACAGGCG GGAGATCTGC 
GACAAGGAGC GCGAGTGCCT CACGAGGAAG CAGGAGCTCC TTCGAGACCG GGAGGCGGCG 
CTGTGGGAGA TGGAGGAGCA TCACCTGCAG GAGAGGCACC AGCTGGTGAA GCAGCAGCTC 
AAAGACCAGT ACTTCCTCCA GCGGCATGAG CTGCTGCGCA AGCATGAGAA GGAGCGCGAG 
CAGATGCAGC GCTACAACCA GCGCATGATC GAGCAGCTGA AGGTGCGGCA GCAGCAGGAG 
AAGGCGCGGC TGCCCAAGAT TCAGAGAAGC GAGGGCAAGA CGCGCATGGC CATGTACAAG 
AAGAGCCTCC ACATCAACGG AGGGGGCAGC GCCGCTGAGC AGCGTGAGAA GATCAAGCAG 
TTCTCCCAGC AGGAAGAAAA GAGGCAGAAG GCAGAGCGGC TGCAGCAGCA GCAGAAACAT 
GAGAACCAGA TGCGGGACAT GTTGGCCCAG TGTGAGAGCA ACATGAGTGA GCTGCAGCAG 
CTGCAGAATG AAAAGTGTCA CCTCCTGATA GAGCACGAAA CCCAGAAGCT GAAGGCCCTG 
GACGAAAGCC ATAACCAGAA CCTGAAGGAA TGGCGGGACA AGCTCCGGCC GCGCAAAAAG 
GCTCTGGAAG AAGATCTGAA CCAGAAAAAG CGAGAGCAGG AGATGTTCTT CAAGATGAAC 
GAGGAGTCAG AGTGTGCGAA TCCCACCTCC CCAAACAAGG TCACCAAGTT CTTCCCCTAC 
AGCTCTGCGG ATGCTGCTTC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001179556.1
CDS	38..2941
Translation	MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETNSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALTFLHGKKIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLSPSKWSAEFRDFLKTALDKNPETRPSAAQLLEHPFVSSVTSNKALRELVAEAKAEVMEEIEDGRDEGDEEDAVEAASPLENHTRDSSEVSQLSIDADKLLKESPFTPPPPSQPQDGANGPSEPPGHGALPATSPLDVAPGNENGQAVPVPLRKFRPVSMGARIQVSEEKQAADQGGDLSPAASRSQKASQSRPNSSALETLRSELTNGSLELPTPGAQSLSKRDSDCGSVSTSGSTDFGTSLSADMSVNKESGSLSIKDSRLHNKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSSKHELQLEQMHKRFEQEINAKKKFFDIELENLERQQKQQVEKMEQDHAVRRREEAKRIRLEQERDYAKFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFLAKQKEDLELAMKRITADNRREICDKERECLTRKQELLRDREAALWEMEEHHLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHINGGGSAAEQREKIKQFSQQEEKRQKAERLQQQQKHENQMRDMLAQCESNMSELQQLQNEKCHLLIEHETQKLKALDESHNQNLKEWRDKLRPRKKALEEDLNQKKREQEMFFKMNEESECANPTSPNKVTKFFPYSSADAAS

Target ORF information:

RefSeq Version	NM_001192627.1
Organism	Bos taurus(cattle)
Definition	Bos taurus serine/threonine kinase 10 (STK10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001192627.1

ORF Insert Sequence:

ATGGCTTTCG CCAATTTCCG CCGCATCCTG CGCCTGTCTA CCTTCGAGAA GAGAAAGTCC 
CGCGAATATG AGCATGTCCG CCGGGACCTG GATCCCAACG AGGTGTGGGA GATCGTGGGC 
GAGCTGGGCG ACGGTGCCTT CGGCAAGGTT TACAAGGCCA AGAACAAGGA GACGGGTGCC 
CTGGCCGCGG CCAAAGTAAT CGAGACCAAC AGCGAGGAGG AGCTGGAAGA CTACATCGTG 
GAGATCGAGA TCCTGGCCAC CTGCGACCAC CCCTACATCG TGAAGCTCCT AGGCGCCTAC 
TACTATGACG GGAAGCTGTG GATTATGATC GAGTTCTGTC CTGGGGGAGC TGTGGATGCC 
ATCATGCTGG AGCTGGACAG AGGCCTCACT GAGCCCCAGA TTCAGGTGGT TTGCCGCCAG 
ATGCTGGAAG CCCTCACCTT CCTGCATGGC AAGAAGATCA TCCACCGGGA CCTGAAAGCC 
GGCAACGTGC TCATGACCCT CGAGGGGGAC ATCAGGCTGG CTGACTTCGG TGTGTCTGCC 
AAGAATCTGA AAACTTTGCA GAAGCGAGAT TCCTTCATAG GAACGCCTTA CTGGATGGCC 
CCCGAGGTGG TGATGTGTGA GACCATGAAG GACACCCCGT ACGACTACAA GGCAGACATC 
TGGTCGCTGG GCATCACGCT GATTGAGATG GCCCAGATCG AGCCCCCGCA CCACGAGCTC 
AACCCCATGC GGGTGCTGCT CAAGATCGCC AAGTCCGATC CTCCCACACT GCTCTCGCCC 
TCTAAGTGGT CTGCAGAGTT CCGAGATTTC CTGAAGACAG CCCTGGATAA GAACCCAGAG 
ACACGGCCCA GCGCTGCGCA GCTCCTGGAG CATCCCTTCG TCAGCAGCGT CACCAGCAAC 
AAGGCCCTGC GGGAGCTGGT GGCCGAGGCC AAGGCTGAAG TGATGGAGGA GATTGAAGAC 
GGCCGAGATG AGGGGGATGA GGAGGATGCG GTGGAGGCTG CCTCTCCTCT GGAGAACCAC 
ACTCGAGACT CCTCCGAGGT GAGTCAGCTG AGCATTGATG CGGACAAACT TCTCAAAGAA 
TCACCTTTCA CCCCACCACC TCCCAGCCAG CCTCAGGATG GTGCGAATGG GCCCAGCGAG 
CCCCCTGGGC ACGGGGCCCT CCCGGCCACC AGCCCCCTGG ATGTGGCCCC TGGAAACGAG 
AATGGCCAGG CGGTGCCTGT GCCCCTCCGG AAGTTCCGAC CAGTGTCCAT GGGTGCCAGA 
ATTCAGGTGT CCGAGGAGAA GCAAGCCGCT GACCAGGGTG GAGACCTCAG TCCAGCGGCC 
AGCAGGTCCC AGAAAGCAAG CCAGAGCCGT CCCAACAGCA GCGCCCTGGA GACCTTGCGC 
AGCGAGCTGA CCAATGGCAG TCTGGAGCTC CCCACCCCGG GGGCACAGAG CCTTTCCAAG 
AGGGACTCAG ATTGTGGCAG CGTCTCCACC TCTGGGAGCA CGGACTTCGG CACCTCCCTG 
TCAGCAGACA TGTCCGTGAA CAAGGAGTCG GGCTCTCTGT CCATCAAGGA CTCAAGGCTG 
CACAATAAGA CCCTGAAGAG GACACGCAAG TTTGTTGTGG ATGGCGTGGA GGTGAGCATT 
ACCACCTCCA AGATCATCAG CGAGGATGAG AAGAAGGACG AGGAGATGCG ATTCCTCAGG 
CGCCAGGAAC TCCGAGAGCT TCGGCTGCTC CAGAAAGAAG AACATCGGAA TCAAACCCAA 
CTGAGCAGCA AGCATGAGCT GCAGCTGGAG CAAATGCATA AGCGTTTTGA ACAAGAAATC 
AACGCCAAGA AGAAGTTCTT TGACATAGAG CTGGAGAACC TGGAGCGTCA GCAAAAGCAA 
CAAGTAGAGA AGATGGAGCA AGACCACGCG GTGCGCCGCC GGGAGGAGGC CAAGCGGATT 
CGCCTGGAGC AGGAGCGGGA CTATGCCAAG TTCCAGGAGC AGCTCAAGCT GATGAAGAAG 
GAGGTGAAGA ATGAGGTGGA GAAGCTCCCC CGGCAGCAGC GGAAGGAGAG CATGAAGCAG 
AAGATGGAGG AGCACACTCA GAAAAAGCAG CTTCTCGACC GGGACTTCCT GGCCAAGCAG 
AAGGAAGACC TGGAGCTGGC CATGAAGAGG ATCACGGCCG ACAACAGGCG GGAGATCTGC 
GACAAGGAGC GCGAGTGCCT CACGAGGAAG CAGGAGCTCC TTCGAGACCG GGAGGCGGCG 
CTGTGGGAGA TGGAGGAGCA TCACCTGCAG GAGAGGCACC AGCTGGTGAA GCAGCAGCTC 
AAAGACCAGT ACTTCCTCCA GCGGCATGAG CTGCTGCGCA AGCATGAGAA GGAGCGCGAG 
CAGATGCAGC GCTACAACCA GCGCATGATC GAGCAGCTGA AGGTGCGGCA GCAGCAGGAG 
AAGGCGCGGC TGCCCAAGAT TCAGAGAAGC GAGGGCAAGA CGCGCATGGC CATGTACAAG 
AAGAGCCTCC ACATCAACGG AGGGGGCAGC GCCGCTGAGC AGCGTGAGAA GATCAAGCAG 
TTCTCCCAGC AGGAAGAAAA GAGGCAGAAG GCAGAGCGGC TGCAGCAGCA GCAGAAACAT 
GAGAACCAGA TGCGGGACAT GTTGGCCCAG TGTGAGAGCA ACATGAGTGA GCTGCAGCAG 
CTGCAGAATG AAAAGTGTCA CCTCCTGATA GAGCACGAAA CCCAGAAGCT GAAGGCCCTG 
GACGAAAGCC ATAACCAGAA CCTGAAGGAA TGGCGGGACA AGCTCCGGCC GCGCAAAAAG 
GCTCTGGAAG AAGATCTGAA CCAGAAAAAG CGAGAGCAGG AGATGTTCTT CAAGATGAAC 
GAGGAGTCAG AGTGTGCGAA TCCCACCTCC CCAAACAAGG TCACCAAGTT CTTCCCCTAC 
AGCTCTGCGG ATGCTGCTTC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America106(12)4707-12(2009 Mar)
Belkina NV,Liu Y,Hao JJ,Karasuyama H,Shaw S

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites.
The EMBO journal27(4)704-14(2008 Feb)
Pike AC,Rellos P,Niesen FH,Turnbull A,Oliver AW,Parker SA,Turk BE,Pearl LH,Knapp S

Stk10, a new member of the polo-like kinase kinase family highly expressed in hematopoietic tissue.
The Journal of biological chemistry278(20)18221-8(2003 May)
Walter SA,Cutler RE Jr,Martinez R,Gishizky M,Hill RJ

Deficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytes.
FEBS letters468(2-3)234-8(2000 Feb)
Endo J,Toyama-Sorimachi N,Taya C,Kuramochi-Miyagawa S,Nagata K,Kuida K,Takashi T,Yonekawa H,Yoshizawa Y,Miyasaka N,Karasuyama H

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STK10 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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