ACVR2B cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	ACVR2B
Entrez Gene ID	282131
Full Name	activin A receptor type 2B
Synonyms	ActR-IIB,ActRIIB
General protein information	Preferred Names activin A receptor type 2B Names activin receptor type-2B activin A receptor, type IIB activin receptor type IIB
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174495.2	NP_776920.1	activin receptor type-2B precursor
XM_010817409.2	XP_010815711.1	activin receptor type-2B isoform X1
XM_024982398.1	XP_024838166.1	activin receptor type-2B isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ACVR2B	XP_542709.2
Homo sapiens (human)	ACVR2B	NP_001097.2
Bos taurus (cattle)	ACVR2B	NP_776920.1
Gallus gallus (chicken)	ACVR2B	NP_989648.1
	ACVR2B	XP_001084713.1
Danio rerio (zebrafish)	acvr2b	NP_571285.1
Pan troglodytes (chimpanzee)	ACVR2B	XP_516369.2
Mus musculus (house mouse)	Acvr2b	NP_031423.1
Rattus norvegicus (Norway rat)	Acvr2b	NP_113742.1
Xenopus tropicalis (tropical clawed frog)	acvr2b	NP_001006871.1

Gene Ontology
Bibliography

Related articles in PubMed

Efficient derivation of bovine embryonic stem cells needs more than active core pluripotency factors.
Maruotti J, Mu?oz M, Degrelle SA, G?mez E, Louet C, D?ez C, Monforte CD, de Longchamp PH, Brochard V, Hue I, Caama?o JN, Jouneau A
Molecular reproduction and development79(7)461-77(2012 Jul)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Expression of bone morphogenetic protein2 (BMP2), BMP4 and BMP receptors in the bovine ovary but absence of effects of BMP2 and BMP4 during IVM on bovine oocyte nuclear maturation and subsequent embryo development.
Fatehi AN, van den Hurk R, Colenbrander B, Daemen AJ, van Tol HT, Monteiro RM, Roelen BA, Bevers MM
Theriogenology63(3)872-89(2005 Feb)

Bovine activin receptor type IIB messenger ribonucleic acid displays alternative splicing involving a sequence homologous to Src-homology 3 domain binding sites.
Ethier JF, Lussier JG, Silversides DW
Endocrinology138(6)2425-34(1997 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ACVR2B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ACVR2B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa41478	NM_174495.2 Latest version!	Bos taurus activin A receptor type 2B (ACVR2B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OBa45384	XM_010817409.2 Latest version!	Bos taurus activin A receptor type IIB (ACVR2B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OBa228735	XM_024982398.1 Latest version!	Bos taurus activin A receptor type 2B (ACVR2B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ACVR2B ( NM_174495.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776920.1 Bos taurus activin A receptor type 2B (ACVR2B), mRNA.

Price & Availability↑

CloneID	OBa41478
Clone ID Related Accession (Same CDS sequence)	NM_174495.2
Accession Version	NM_174495.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1539bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Bos taurus(cattle)
Product	activin receptor type-2B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U57707.1. On Jun 3, 2003 this sequence version replaced NM_174495.1. ##Evidence-Data-START## Transcript exon combination :: U57707.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145433, SAMN03145447 [ECO:0000348] ##Evidence-Data-END##

ATGACGGCGC CCTGGGCGGC CCTCGCCCTC CTTTGGGGAT CGCTGTGCGC CGGTTCGGGG 
CGCGGGGAGG CCGAGACACG GGAGTGCATC TACTACAACG CCAACTGGGA GCTGGAGCGC 
ACCAACCAGA GCGGCCTGGA GCGCTGCGAG GGCGAGCGGG ACAAGCGGCT GCACTGCTAC 
GCCTCCTGGC GCAACAGCTC GGGCACCATC GAGCTCGTCA AGAAAGGCTG CTGGCTGGAC 
GACTTCAACT GCTACGACAG GCAGGAGTGC GTGGCCACCG AGGAGAACCC CCAGGTGTAC 
TTCTGCTGCT GCGAAGGCAA CTTCTGCAAC GAGCGCTTCA CCCACCTGCC CGAGGCGGGC 
GGCCCAGAAG TCACGTACGA GCCACCCCCG ACAGCCCCCA CCCTGCTCAC TGTGCTGGCC 
TACTCGCTGC TGCCCGTCGG GGGCCTCTCC CTCATCGCCC TGCTGGCCTT CTGGATGTAC 
CGACATCGCA AGCCCCCCTA CGGCCACGCG GACATCCACG AGGACCCTGG ACCTCCACCC 
CCGTCCCCTC TGGTGGGCCT GAAGCCTCTG CAACTGCTGG AGATCAAGGC TCGGGGGCGC 
TTTGGTTGTG TCTGGAAGGC GCAGCTCATG AACGACTTCG TGGCTGTCAA GATCTTCCCA 
CTCCAGGACA AGCAGTCGTG GCAGAGTGAG CGGGAGATCT TCAGCACGCC TGGCATGAAG 
CACGAGAACC TGCTGCAGTT CATTGCCGCT GAGAAGCGAG GCTCCAGCCT GGAGGCAGAG 
CTGTGGCTCA TCACGGCCTT CCACGACAAG GGCTCCCTCA CGGATTACCT CAAGGGGAAC 
ATCATCACAT GGAACGAACT GTGTCACGTG GCAGAGACGA TGTCTAGAGG CCTCTCATAC 
CTACACGAGG ATGTGCCCTG GTGCCGGGGC GAGGGCCACA AGCCATCTAT TGCCCACAGG 
GACTTTAAGA GCAAGAATGT ATTGCTGAAG AGTGACCTCA CTGCTGTGCT GGCTGACTTT 
GGCCTGGCTG TTCGGTTTGA GCCAGGGAAA CCTCCGGGGG ACACTCACGG GCAGGTGGGC 
ACGCGGCGGT ACATGGCCCC CGAGGTGCTC GAGGGAGCCA TCAACTTCCA GAGAGACGCC 
TTTCTGCGCA TCGACATGTA CGCCATGGGG CTGGTGCTGT GGGAGCTCGT GTCCCGCTGC 
AAAGCTGCCG ATGGACCTGT GGATGAGTAC ATGCTGCCTT TTGAGGAGGA GATCGGCCAG 
CACCCGTCAC TGGAGGAGCT GCAGGAGGTG GTGGTGCACA AGAAGATGCG GCCCGCCATC 
AAGGATCACT GGCTGAAACA CCCGGGCCTG GCCCAGCTCT GCGTGACCAT CGAGGAGTGC 
TGGGACCACG ATGCAGAGGC TCGCCTGTCT GCGGGCTGTG TGGAGGAGCG AGTGTCCCTG 
ATCCGGAGGT CGGTCAACGG CACTACCTCG GACTGTCTTG TCTCCCTGGT GACCTCCGTC 
ACCAATGTGG ACCTGCCCCC GAAGGAGTCG AGCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776920.1
CDS	159..1697
Translation	MTAPWAALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGERDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPVGGLSLIALLAFWMYRHRKPPYGHADIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSSLEAELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPAIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	NM_174495.2
Organism	Bos taurus(cattle)
Definition	Bos taurus activin A receptor type 2B (ACVR2B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174495.2

ORF Insert Sequence:

ATGACGGCGC CCTGGGCGGC CCTCGCCCTC CTTTGGGGAT CGCTGTGCGC CGGTTCGGGG 
CGCGGGGAGG CCGAGACACG GGAGTGCATC TACTACAACG CCAACTGGGA GCTGGAGCGC 
ACCAACCAGA GCGGCCTGGA GCGCTGCGAG GGCGAGCGGG ACAAGCGGCT GCACTGCTAC 
GCCTCCTGGC GCAACAGCTC GGGCACCATC GAGCTCGTCA AGAAAGGCTG CTGGCTGGAC 
GACTTCAACT GCTACGACAG GCAGGAGTGC GTGGCCACCG AGGAGAACCC CCAGGTGTAC 
TTCTGCTGCT GCGAAGGCAA CTTCTGCAAC GAGCGCTTCA CCCACCTGCC CGAGGCGGGC 
GGCCCAGAAG TCACGTACGA GCCACCCCCG ACAGCCCCCA CCCTGCTCAC TGTGCTGGCC 
TACTCGCTGC TGCCCGTCGG GGGCCTCTCC CTCATCGCCC TGCTGGCCTT CTGGATGTAC 
CGACATCGCA AGCCCCCCTA CGGCCACGCG GACATCCACG AGGACCCTGG ACCTCCACCC 
CCGTCCCCTC TGGTGGGCCT GAAGCCTCTG CAACTGCTGG AGATCAAGGC TCGGGGGCGC 
TTTGGTTGTG TCTGGAAGGC GCAGCTCATG AACGACTTCG TGGCTGTCAA GATCTTCCCA 
CTCCAGGACA AGCAGTCGTG GCAGAGTGAG CGGGAGATCT TCAGCACGCC TGGCATGAAG 
CACGAGAACC TGCTGCAGTT CATTGCCGCT GAGAAGCGAG GCTCCAGCCT GGAGGCAGAG 
CTGTGGCTCA TCACGGCCTT CCACGACAAG GGCTCCCTCA CGGATTACCT CAAGGGGAAC 
ATCATCACAT GGAACGAACT GTGTCACGTG GCAGAGACGA TGTCTAGAGG CCTCTCATAC 
CTACACGAGG ATGTGCCCTG GTGCCGGGGC GAGGGCCACA AGCCATCTAT TGCCCACAGG 
GACTTTAAGA GCAAGAATGT ATTGCTGAAG AGTGACCTCA CTGCTGTGCT GGCTGACTTT 
GGCCTGGCTG TTCGGTTTGA GCCAGGGAAA CCTCCGGGGG ACACTCACGG GCAGGTGGGC 
ACGCGGCGGT ACATGGCCCC CGAGGTGCTC GAGGGAGCCA TCAACTTCCA GAGAGACGCC 
TTTCTGCGCA TCGACATGTA CGCCATGGGG CTGGTGCTGT GGGAGCTCGT GTCCCGCTGC 
AAAGCTGCCG ATGGACCTGT GGATGAGTAC ATGCTGCCTT TTGAGGAGGA GATCGGCCAG 
CACCCGTCAC TGGAGGAGCT GCAGGAGGTG GTGGTGCACA AGAAGATGCG GCCCGCCATC 
AAGGATCACT GGCTGAAACA CCCGGGCCTG GCCCAGCTCT GCGTGACCAT CGAGGAGTGC 
TGGGACCACG ATGCAGAGGC TCGCCTGTCT GCGGGCTGTG TGGAGGAGCG AGTGTCCCTG 
ATCCGGAGGT CGGTCAACGG CACTACCTCG GACTGTCTTG TCTCCCTGGT GACCTCCGTC 
ACCAATGTGG ACCTGCCCCC GAAGGAGTCG AGCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACVR2B ( XM_010817409.2 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010815711.1 Bos taurus activin A receptor type IIB (ACVR2B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa45384
Clone ID Related Accession (Same CDS sequence)	XM_010817409.2
Accession Version	XM_010817409.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1626bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	activin receptor type-2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_010817409.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGATCA GAACCGTGAC GTCCGATTTC ACCCTGCTCC GGTTAGCACG TCGCAGGGCT 
CGGGGTGGCT CAGTGGGTCT GGAGTCTCTT GGGCACGTAC AGAGTACATC CACGTGGGAG 
AACAGTGTGA CCGTGACCTG TTCGGGGCGC GGGGAGGCCG AGACACGGGA GTGCATCTAC 
TACAACGCCA ACTGGGAGCT GGAGCGCACC AACCAGAGCG GCCTGGAGCG CTGCGAGGGC 
GAGCGGGACA AGCGGCTGCA CTGCTACGCC TCCTGGCGCA ACAGCTCGGG CACCATCGAG 
CTCGTCAAGA AAGGCTGCTG GCTGGACGAC TTCAACTGCT ACGACAGGCA GGAGTGCGTG 
GCCACCGAGG AGAACCCCCA GGTGTACTTC TGCTGCTGCG AAGGCAACTT CTGCAACGAG 
CGCTTCACCC ACCTGCCCGA GGCGGGCGGC CCAGAAGTCA CGTACGAGCC ACCCCCGACA 
GCCCCCACCC TGCTCACTGT GCTGGCCTAC TCGCTGCTGC CCGTCGGGGG CCTCTCCCTC 
ATCGCCCTGC TGGCCTTCTG GATGTACCGA CATCGCAAGC CCCCCTACGG CCACGTGGAC 
ATCCACGAGG ACCCTGGACC TCCACCCCCG TCCCCTCTGG TGGGCCTGAA GCCTCTGCAA 
CTGCTGGAGA TCAAGGCTCG GGGGCGCTTT GGTTGTGTCT GGAAGGCGCA GCTCATGAAC 
GACTTCGTGG CTGTCAAGAT CTTCCCACTC CAGGACAAGC AGTCGTGGCA GAGTGAGCGG 
GAGATCTTCA GCACGCCTGG CATGAAGCAC GAGAACCTGC TGCAGTTCAT TGCCGCTGAG 
AAGCGAGGCT CCAGCCTGGA GGCAGAGCTG TGGCTCATCA CGGCCTTCCA CGACAAGGGC 
TCCCTCACGG ATTACCTCAA GGGGAACATC ATCACATGGA ACGAACTGTG TCACGTGGCA 
GAGACGATGT CTAGAGGCCT CTCATACCTA CACGAGGATG TGCCCTGGTG CCGGGGCGAG 
GGCCACAAGC CATCTATTGC CCACAGGGAC TTTAAGAGCA AGAATGTATT GCTGAAGAGT 
GACCTCACTG CTGTGCTGGC TGACTTTGGC CTGGCTGTTC GGTTTGAGCC AGGGAAACCT 
CCGGGGGACA CTCACGGGCA GGTGGGCACG CGGCGGTACA TGGCCCCCGA GGTGCTCGAG 
GGAGCCATCA ACTTCCAGAG AGACGCCTTT CTGCGCATCG ACATGTACGC CATGGGGCTG 
GTGCTGTGGG AGCTCGTGTC CCGCTGCAAA GCTGCCGATG GACCTGTGGA TGAGTACATG 
CTGCCTTTTG AGGAGGAGAT CGGCCAGCAC CCGTCACTGG AGGAGCTGCA GGAGGTGGTG 
GTGCACAAGA AGATGCGGCC CGCCATCAAG GATCACTGGC TGAAACACCC GGGCCTGGCC 
CAGCTCTGCG TGACCATCGA GGAGTGCTGG GACCACGATG CAGAGGCTCG CCTGTCTGCG 
GGCTGTGTGG AGGAGCGAGT GTCCCTGATC CGGAGGTCGG TCAACGGCAC TACCTCGGAC 
TGTCTTGTCT CCCTGGTGAC CTCCGTCACC AATGTGGACC TGCCCCCGAA GGAGTCGAGC 
ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010815711.1
CDS	667..2292
Translation	MGIRTVTSDFTLLRLARRRARGGSVGLESLGHVQSTSTWENSVTVTCSGRGEAETRECIYYNANWELERTNQSGLERCEGERDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPVGGLSLIALLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSSLEAELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPAIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	XM_010817409.2
Organism	Bos taurus(cattle)
Definition	Bos taurus activin A receptor type IIB (ACVR2B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010817409.2

ORF Insert Sequence:

ATGGGGATCA GAACCGTGAC GTCCGATTTC ACCCTGCTCC GGTTAGCACG TCGCAGGGCT 
CGGGGTGGCT CAGTGGGTCT GGAGTCTCTT GGGCACGTAC AGAGTACATC CACGTGGGAG 
AACAGTGTGA CCGTGACCTG TTCGGGGCGC GGGGAGGCCG AGACACGGGA GTGCATCTAC 
TACAACGCCA ACTGGGAGCT GGAGCGCACC AACCAGAGCG GCCTGGAGCG CTGCGAGGGC 
GAGCGGGACA AGCGGCTGCA CTGCTACGCC TCCTGGCGCA ACAGCTCGGG CACCATCGAG 
CTCGTCAAGA AAGGCTGCTG GCTGGACGAC TTCAACTGCT ACGACAGGCA GGAGTGCGTG 
GCCACCGAGG AGAACCCCCA GGTGTACTTC TGCTGCTGCG AAGGCAACTT CTGCAACGAG 
CGCTTCACCC ACCTGCCCGA GGCGGGCGGC CCAGAAGTCA CGTACGAGCC ACCCCCGACA 
GCCCCCACCC TGCTCACTGT GCTGGCCTAC TCGCTGCTGC CCGTCGGGGG CCTCTCCCTC 
ATCGCCCTGC TGGCCTTCTG GATGTACCGA CATCGCAAGC CCCCCTACGG CCACGTGGAC 
ATCCACGAGG ACCCTGGACC TCCACCCCCG TCCCCTCTGG TGGGCCTGAA GCCTCTGCAA 
CTGCTGGAGA TCAAGGCTCG GGGGCGCTTT GGTTGTGTCT GGAAGGCGCA GCTCATGAAC 
GACTTCGTGG CTGTCAAGAT CTTCCCACTC CAGGACAAGC AGTCGTGGCA GAGTGAGCGG 
GAGATCTTCA GCACGCCTGG CATGAAGCAC GAGAACCTGC TGCAGTTCAT TGCCGCTGAG 
AAGCGAGGCT CCAGCCTGGA GGCAGAGCTG TGGCTCATCA CGGCCTTCCA CGACAAGGGC 
TCCCTCACGG ATTACCTCAA GGGGAACATC ATCACATGGA ACGAACTGTG TCACGTGGCA 
GAGACGATGT CTAGAGGCCT CTCATACCTA CACGAGGATG TGCCCTGGTG CCGGGGCGAG 
GGCCACAAGC CATCTATTGC CCACAGGGAC TTTAAGAGCA AGAATGTATT GCTGAAGAGT 
GACCTCACTG CTGTGCTGGC TGACTTTGGC CTGGCTGTTC GGTTTGAGCC AGGGAAACCT 
CCGGGGGACA CTCACGGGCA GGTGGGCACG CGGCGGTACA TGGCCCCCGA GGTGCTCGAG 
GGAGCCATCA ACTTCCAGAG AGACGCCTTT CTGCGCATCG ACATGTACGC CATGGGGCTG 
GTGCTGTGGG AGCTCGTGTC CCGCTGCAAA GCTGCCGATG GACCTGTGGA TGAGTACATG 
CTGCCTTTTG AGGAGGAGAT CGGCCAGCAC CCGTCACTGG AGGAGCTGCA GGAGGTGGTG 
GTGCACAAGA AGATGCGGCC CGCCATCAAG GATCACTGGC TGAAACACCC GGGCCTGGCC 
CAGCTCTGCG TGACCATCGA GGAGTGCTGG GACCACGATG CAGAGGCTCG CCTGTCTGCG 
GGCTGTGTGG AGGAGCGAGT GTCCCTGATC CGGAGGTCGG TCAACGGCAC TACCTCGGAC 
TGTCTTGTCT CCCTGGTGAC CTCCGTCACC AATGTGGACC TGCCCCCGAA GGAGTCGAGC 
ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACVR2B ( XM_024982398.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_024838166.1 Bos taurus activin A receptor type 2B (ACVR2B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa228735
Clone ID Related Accession (Same CDS sequence)	XM_024982398.1
Accession Version	XM_024982398.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1752bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	activin receptor type-2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037349.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCGCCG GCACCACGGC CCCGACCCGG GGGTTGATCT CTTCCGGCGC CTGTTGGTTG 
TTCTTGGCAG ACTGGCAGCT CCCTGTTCCT CCTCCCCTCC TCCCCCAATC TACTCGCACT 
TCGACGCCGG AGCCTTCTGC GGGGGATCTC CTCTCTGATC TTGAGATCAG CAAGATACAC 
CGTGCTGAAC TGAGCACTAT TACAGAGTGG GAGGAAGCAG TCCCCAAAGC TTCAGTTTCC 
AAGTGCTCCC TGTCGCTGCT GTGTGGTTCG GGGCGCGGGG AGGCCGAGAC ACGGGAGTGC 
ATCTACTACA ACGCCAACTG GGAGCTGGAG CGCACCAACC AGAGCGGCCT GGAGCGCTGC 
GAGGGCGAGC GGGACAAGCG GCTGCACTGC TACGCCTCCT GGCGCAACAG CTCGGGCACC 
ATCGAGCTCG TCAAGAAAGG CTGCTGGCTG GACGACTTCA ACTGCTACGA CAGGCAGGAG 
TGCGTGGCCA CCGAGGAGAA CCCCCAGGTG TACTTCTGCT GCTGCGAAGG CAACTTCTGC 
AACGAGCGCT TCACCCACCT GCCCGAGGCG GGCGGCCCAG AAGTCACGTA CGAGCCACCC 
CCGACAGCCC CCACCCTGCT CACTGTGCTG GCCTACTCGC TGCTGCCCGT CGGGGGCCTC 
TCCCTCATCG CCCTGCTGGC CTTCTGGATG TACCGACATC GCAAGCCCCC CTACGGCCAC 
GTGGACATCC ACGAGGACCC TGGACCTCCA CCCCCGTCCC CTCTGGTGGG CCTGAAGCCT 
CTGCAACTGC TGGAGATCAA GGCTCGGGGG CGCTTTGGTT GTGTCTGGAA GGCGCAGCTC 
ATGAACGACT TCGTGGCTGT CAAGATCTTC CCACTCCAGG ACAAGCAGTC GTGGCAGAGT 
GAGCGGGAGA TCTTCAGCAC GCCTGGCATG AAGCACGAGA ACCTGCTGCA GTTCATTGCC 
GCTGAGAAGC GAGGCTCCAG CCTGGAGGCA GAGCTGTGGC TCATCACGGC CTTCCACGAC 
AAGGGCTCCC TCACGGATTA CCTCAAGGGG AACATCATCA CATGGAACGA ACTGTGTCAC 
GTGGCAGAGA CGATGTCTAG AGGCCTCTCA TACCTACACG AGGATGTGCC CTGGTGCCGG 
GGCGAGGGCC ACAAGCCATC TATTGCCCAC AGGGACTTTA AGAGCAAGAA TGTATTGCTG 
AAGAGTGACC TCACTGCTGT GCTGGCTGAC TTTGGCCTGG CTGTTCGGTT TGAGCCAGGG 
AAACCTCCGG GGGACACTCA CGGGCAGGTG GGCACGCGGC GGTACATGGC CCCCGAGGTG 
CTCGAGGGAG CCATCAACTT CCAGAGAGAC GCCTTTCTGC GCATCGACAT GTACGCCATG 
GGGCTGGTGC TGTGGGAGCT CGTGTCCCGC TGCAAAGCTG CCGATGGACC TGTGGATGAG 
TACATGCTGC CTTTTGAGGA GGAGATCGGC CAGCACCCGT CACTGGAGGA GCTGCAGGAG 
GTGGTGGTGC ACAAGAAGAT GCGGCCCGCC ATCAAGGATC ACTGGCTGAA ACACCCGGGC 
CTGGCCCAGC TCTGCGTGAC CATCGAGGAG TGCTGGGACC ACGATGCAGA GGCTCGCCTG 
TCTGCGGGCT GTGTGGAGGA GCGAGTGTCC CTGATCCGGA GGTCGGTCAA CGGCACTACC 
TCGGACTGTC TTGTCTCCCT GGTGACCTCC GTCACCAATG TGGACCTGCC CCCGAAGGAG 
TCGAGCATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024838166.1
CDS	66..1817
Translation	MGAGTTAPTRGLISSGACWLFLADWQLPVPPPLLPQSTRTSTPEPSAGDLLSDLEISKIHRAELSTITEWEEAVPKASVSKCSLSLLCGSGRGEAETRECIYYNANWELERTNQSGLERCEGERDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPVGGLSLIALLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSSLEAELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPAIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	XM_024982398.1
Organism	Bos taurus(cattle)
Definition	Bos taurus activin A receptor type 2B (ACVR2B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024982398.1

ORF Insert Sequence:

ATGGGCGCCG GCACCACGGC CCCGACCCGG GGGTTGATCT CTTCCGGCGC CTGTTGGTTG 
TTCTTGGCAG ACTGGCAGCT CCCTGTTCCT CCTCCCCTCC TCCCCCAATC TACTCGCACT 
TCGACGCCGG AGCCTTCTGC GGGGGATCTC CTCTCTGATC TTGAGATCAG CAAGATACAC 
CGTGCTGAAC TGAGCACTAT TACAGAGTGG GAGGAAGCAG TCCCCAAAGC TTCAGTTTCC 
AAGTGCTCCC TGTCGCTGCT GTGTGGTTCG GGGCGCGGGG AGGCCGAGAC ACGGGAGTGC 
ATCTACTACA ACGCCAACTG GGAGCTGGAG CGCACCAACC AGAGCGGCCT GGAGCGCTGC 
GAGGGCGAGC GGGACAAGCG GCTGCACTGC TACGCCTCCT GGCGCAACAG CTCGGGCACC 
ATCGAGCTCG TCAAGAAAGG CTGCTGGCTG GACGACTTCA ACTGCTACGA CAGGCAGGAG 
TGCGTGGCCA CCGAGGAGAA CCCCCAGGTG TACTTCTGCT GCTGCGAAGG CAACTTCTGC 
AACGAGCGCT TCACCCACCT GCCCGAGGCG GGCGGCCCAG AAGTCACGTA CGAGCCACCC 
CCGACAGCCC CCACCCTGCT CACTGTGCTG GCCTACTCGC TGCTGCCCGT CGGGGGCCTC 
TCCCTCATCG CCCTGCTGGC CTTCTGGATG TACCGACATC GCAAGCCCCC CTACGGCCAC 
GTGGACATCC ACGAGGACCC TGGACCTCCA CCCCCGTCCC CTCTGGTGGG CCTGAAGCCT 
CTGCAACTGC TGGAGATCAA GGCTCGGGGG CGCTTTGGTT GTGTCTGGAA GGCGCAGCTC 
ATGAACGACT TCGTGGCTGT CAAGATCTTC CCACTCCAGG ACAAGCAGTC GTGGCAGAGT 
GAGCGGGAGA TCTTCAGCAC GCCTGGCATG AAGCACGAGA ACCTGCTGCA GTTCATTGCC 
GCTGAGAAGC GAGGCTCCAG CCTGGAGGCA GAGCTGTGGC TCATCACGGC CTTCCACGAC 
AAGGGCTCCC TCACGGATTA CCTCAAGGGG AACATCATCA CATGGAACGA ACTGTGTCAC 
GTGGCAGAGA CGATGTCTAG AGGCCTCTCA TACCTACACG AGGATGTGCC CTGGTGCCGG 
GGCGAGGGCC ACAAGCCATC TATTGCCCAC AGGGACTTTA AGAGCAAGAA TGTATTGCTG 
AAGAGTGACC TCACTGCTGT GCTGGCTGAC TTTGGCCTGG CTGTTCGGTT TGAGCCAGGG 
AAACCTCCGG GGGACACTCA CGGGCAGGTG GGCACGCGGC GGTACATGGC CCCCGAGGTG 
CTCGAGGGAG CCATCAACTT CCAGAGAGAC GCCTTTCTGC GCATCGACAT GTACGCCATG 
GGGCTGGTGC TGTGGGAGCT CGTGTCCCGC TGCAAAGCTG CCGATGGACC TGTGGATGAG 
TACATGCTGC CTTTTGAGGA GGAGATCGGC CAGCACCCGT CACTGGAGGA GCTGCAGGAG 
GTGGTGGTGC ACAAGAAGAT GCGGCCCGCC ATCAAGGATC ACTGGCTGAA ACACCCGGGC 
CTGGCCCAGC TCTGCGTGAC CATCGAGGAG TGCTGGGACC ACGATGCAGA GGCTCGCCTG 
TCTGCGGGCT GTGTGGAGGA GCGAGTGTCC CTGATCCGGA GGTCGGTCAA CGGCACTACC 
TCGGACTGTC TTGTCTCCCT GGTGACCTCC GTCACCAATG TGGACCTGCC CCCGAAGGAG 
TCGAGCATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Efficient derivation of bovine embryonic stem cells needs more than active core pluripotency factors.
Molecular reproduction and development79(7)461-77(2012 Jul)
Maruotti J,Mu?oz M,Degrelle SA,G?mez E,Louet C,D?ez C,Monforte CD,de Longchamp PH,Brochard V,Hue I,Caama?o JN,Jouneau A

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Expression of bone morphogenetic protein2 (BMP2), BMP4 and BMP receptors in the bovine ovary but absence of effects of BMP2 and BMP4 during IVM on bovine oocyte nuclear maturation and subsequent embryo development.
Theriogenology63(3)872-89(2005 Feb)
Fatehi AN,van den Hurk R,Colenbrander B,Daemen AJ,van Tol HT,Monteiro RM,Roelen BA,Bevers MM

Bovine activin receptor type IIB messenger ribonucleic acid displays alternative splicing involving a sequence homologous to Src-homology 3 domain binding sites.
Endocrinology138(6)2425-34(1997 Jun)
Ethier JF,Lussier JG,Silversides DW