foxc1-A cDNA ORF clone, Xenopus laevis(African clawed frog)

Gene
Clones
gRNAs

Summary

Gene Symbol	foxc1-A
Entrez Gene ID	394280
Full Name	winged helix transcription factor XFD-11
Synonyms	XFD-11
Gene Type	protein-coding
Organism	Xenopus laevis(African clawed frog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001087468.1	NP_001080937.1	winged helix transcription factor XFD-11

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

The role of FoxC1 in early Xenopus development.
Cha JY, Birsoy B, Kofron M, Mahoney E, Lang S, Wylie C, Heasman J
Developmental dynamics : an official publication of the American Association of Anatomists236(10)2731-41(2007 Oct)

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW, Richardson P
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)

Expression pattern of the winged helix factor XFD-11 during Xenopus embryogenesis.
K?ster M, Dillinger K, Kn?chel W
Mechanisms of development76(1-2)169-73(1998 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

at late neurula to early tailbud stage, FoxC1 depletion causes down-regulation of adhesion molecules, EP & E cadherin, & members of the Ephrin/EphR signaling families in the mesoderm germ layer resulting in loss of adhesion & apoptosis of mesodermal cells
Title: The role of FoxC1 in early Xenopus development.

The following foxc1-A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the foxc1-A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OAf07654	NM_001087468.1 Latest version!	Xenopus laevis winged helix transcription factor XFD-11 (foxc1-A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

foxc1-A ( NM_001087468.1 ) cDNA ORF clone, Xenopus laevis(African clawed frog) -> NP_001080937.1 Xenopus laevis winged helix transcription factor XFD-11 (foxc1-A), mRNA.

Price & Availability↑

CloneID	OAf07654
Clone ID Related Accession (Same CDS sequence)	NM_001087468.1
Accession Version	NM_001087468.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Xenopus laevis(African clawed frog)
Product	winged helix transcription factor XFD-11
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF116844.1. ##Evidence-Data-START## Transcript exon combination :: AF116844.1 [ECO:0000332] ##Evidence-Data-END##

ATGCAGGCGC GCTACTCGGT GTCCAGCCCC AACTCCCTGG GAGTCGTGCC CTACCTCAGC 
GGGGAGCAGA GTTACTACAG GGCGGCTGCA GCGGCGGCGG CGGCAGGAGG AGGCTACACG 
GGCATGGCTG CCCCCATGAG TATGTACTCA TTCCCCGCGC ATGAACAGTA CCAGGCCGGC 
ATGGCAGAAG CCTATGGGCC CTACGCCCCC CAGCCCCAGC CCAAGGACAT GGTGAAGCCC 
CCCTACAGCT ACATCGCTCT CATCACCATG GCCATCCAGA ACGCCCCCGA CAAGAAGATC 
ACCCTGAATG GCATCTACCA GTTCATCATG GAGAGGTTCC CCTTCTACCG GGACAACAAG 
CAGGGCTGGC AGAACAGTAT CAGGCACAAC CTGTCCCTCA ACGAGTGCTT TGTCAAGGTG 
CCAAGAGACG ACAAGAAGCC GGGCAAGGGC AGCTACTGGA CCCTGGACCC GGACTCGTAC 
AACATGTTTG AGAATGGCAG CTTTCTGAGG AGGAGGCGCA GGTTCAAGAA AAAAGATGTG 
TCCAAAGATG CCACCAAGGA GGACAAAGAG CGTCTACTGA AAGAGCATCA TGGCAGCCAA 
TCCGCAGCCG CGCAACAGCA GCGCCAGCAG CAGCAGAGCC AGGCCCAAGC GGAACAGGAC 
AGCAACTCCC AGCCGGTTAG GATTCAGGAT ATAAAGACAG AGAACGGCAC TTCTTCTCCT 
CTTCAGTCCA TGTCTCCTGC ACTCAGCGCT GTGCCCAAGA TAGAGAGTCC GGACAGCAGC 
AGCAGCATGT CCAGTGGCAG CCCCCACAGC ATTCCGTCCA ACAGGTCCAT GAGTCTGGAG 
GCTGCAGAGT CTCACCACCC GCACCACCAG CAGCACAGCC AGGGCTTCAG CGTGGATAAC 
ATCATGACCT CTCTCAGGGG CTCCCCGCAG GGCTCAGCAG AACTGCCTTC TCCCCTCATC 
TCTTCTTCCA GGACAGGTAT CGCCCCCTCC TTGTCCCTAT CCTACTCCCC AGGCCAGGGC 
TCCATCTACA GCTCCCCCTG CAGTCAGGGC ACAAGCAGTG GCGGTGGGGC AGGGACCTAT 
CACTGTAATA TGCAGGCCAT GAGCTTGTAT TCTGGGGACA GGTCGGGACA CTTAACTCCT 
GCCAACACCC CAGCAGCCAC CACAGTGGAA GAGACCTTAC CTGACTATTC CATCTCTACC 
ACCTCTGCCC AGAGCCATGG CAACCAGGAG CACCCTCACC AGGGCCGATT GCCCTCTTGG 
TATCTCAATC AAACTGGGGA ATTGGGCCAC TTGGCCGGGG CCACCTACCC GGGGCAGCAG 
CAGAACTTCC ACTCGGTGCG AGAGATGTTT GAGTCGCAGC GATTAGCTTT GAACAGTTCC 
CCTGTGAATG GAAATAGCAG CTGTCAGATG TCTTTCCCCC CCAGCCAGTC CTTGTATCGC 
ACCTCGGGGG CGTTTGTCTA TGACTGCAGC AAATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001080937.1
CDS	357..1835
Translation	MQARYSVSSPNSLGVVPYLSGEQSYYRAAAAAAAAGGGYTGMAAPMSMYSFPAHEQYQAGMAEAYGPYAPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKDATKEDKERLLKEHHGSQSAAAQQQRQQQQSQAQAEQDSNSQPVRIQDIKTENGTSSPLQSMSPALSAVPKIESPDSSSSMSSGSPHSIPSNRSMSLEAAESHHPHHQQHSQGFSVDNIMTSLRGSPQGSAELPSPLISSSRTGIAPSLSLSYSPGQGSIYSSPCSQGTSSGGGAGTYHCNMQAMSLYSGDRSGHLTPANTPAATTVEETLPDYSISTTSAQSHGNQEHPHQGRLPSWYLNQTGELGHLAGATYPGQQQNFHSVREMFESQRLALNSSPVNGNSSCQMSFPPSQSLYRTSGAFVYDCSKF

Target ORF information:

RefSeq Version	NM_001087468.1
Organism	Xenopus laevis(African clawed frog)
Definition	Xenopus laevis winged helix transcription factor XFD-11 (foxc1-A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001087468.1

ORF Insert Sequence:

ATGCAGGCGC GCTACTCGGT GTCCAGCCCC AACTCCCTGG GAGTCGTGCC CTACCTCAGC 
GGGGAGCAGA GTTACTACAG GGCGGCTGCA GCGGCGGCGG CGGCAGGAGG AGGCTACACG 
GGCATGGCTG CCCCCATGAG TATGTACTCA TTCCCCGCGC ATGAACAGTA CCAGGCCGGC 
ATGGCAGAAG CCTATGGGCC CTACGCCCCC CAGCCCCAGC CCAAGGACAT GGTGAAGCCC 
CCCTACAGCT ACATCGCTCT CATCACCATG GCCATCCAGA ACGCCCCCGA CAAGAAGATC 
ACCCTGAATG GCATCTACCA GTTCATCATG GAGAGGTTCC CCTTCTACCG GGACAACAAG 
CAGGGCTGGC AGAACAGTAT CAGGCACAAC CTGTCCCTCA ACGAGTGCTT TGTCAAGGTG 
CCAAGAGACG ACAAGAAGCC GGGCAAGGGC AGCTACTGGA CCCTGGACCC GGACTCGTAC 
AACATGTTTG AGAATGGCAG CTTTCTGAGG AGGAGGCGCA GGTTCAAGAA AAAAGATGTG 
TCCAAAGATG CCACCAAGGA GGACAAAGAG CGTCTACTGA AAGAGCATCA TGGCAGCCAA 
TCCGCAGCCG CGCAACAGCA GCGCCAGCAG CAGCAGAGCC AGGCCCAAGC GGAACAGGAC 
AGCAACTCCC AGCCGGTTAG GATTCAGGAT ATAAAGACAG AGAACGGCAC TTCTTCTCCT 
CTTCAGTCCA TGTCTCCTGC ACTCAGCGCT GTGCCCAAGA TAGAGAGTCC GGACAGCAGC 
AGCAGCATGT CCAGTGGCAG CCCCCACAGC ATTCCGTCCA ACAGGTCCAT GAGTCTGGAG 
GCTGCAGAGT CTCACCACCC GCACCACCAG CAGCACAGCC AGGGCTTCAG CGTGGATAAC 
ATCATGACCT CTCTCAGGGG CTCCCCGCAG GGCTCAGCAG AACTGCCTTC TCCCCTCATC 
TCTTCTTCCA GGACAGGTAT CGCCCCCTCC TTGTCCCTAT CCTACTCCCC AGGCCAGGGC 
TCCATCTACA GCTCCCCCTG CAGTCAGGGC ACAAGCAGTG GCGGTGGGGC AGGGACCTAT 
CACTGTAATA TGCAGGCCAT GAGCTTGTAT TCTGGGGACA GGTCGGGACA CTTAACTCCT 
GCCAACACCC CAGCAGCCAC CACAGTGGAA GAGACCTTAC CTGACTATTC CATCTCTACC 
ACCTCTGCCC AGAGCCATGG CAACCAGGAG CACCCTCACC AGGGCCGATT GCCCTCTTGG 
TATCTCAATC AAACTGGGGA ATTGGGCCAC TTGGCCGGGG CCACCTACCC GGGGCAGCAG 
CAGAACTTCC ACTCGGTGCG AGAGATGTTT GAGTCGCAGC GATTAGCTTT GAACAGTTCC 
CCTGTGAATG GAAATAGCAG CTGTCAGATG TCTTTCCCCC CCAGCCAGTC CTTGTATCGC 
ACCTCGGGGG CGTTTGTCTA TGACTGCAGC AAATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The role of FoxC1 in early Xenopus development.
Developmental dynamics : an official publication of the American Association of Anatomists236(10)2731-41(2007 Oct)
Cha JY,Birsoy B,Kofron M,Mahoney E,Lang S,Wylie C,Heasman J

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)
Klein SL,Strausberg RL,Wagner L,Pontius J,Clifton SW,Richardson P

Expression pattern of the winged helix factor XFD-11 during Xenopus embryogenesis.
Mechanisms of development76(1-2)169-73(1998 Aug)
K?ster M,Dillinger K,Kn?chel W