fgf4.S cDNA ORF clone, Xenopus laevis(African clawed frog)

Gene
Clones
gRNAs

Summary

Gene Symbol	fgf4.S
Entrez Gene ID	378587
Full Name	fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene) S homeolog
Synonyms	FGF(ii),HBGF-4,XEFGF,Xfgf-4,Xfgf4,efgf,fgf-4,fgf4,fgf4-a,fgf4-b,fgfe,fgfe-B
General protein information	Preferred Names fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene) S homeolog Names fibroblast growth factor 4B FGF-4-II FGF-4B HBGF-4-II embryonic fibroblast growth factor II fibroblast growth factor 4-II heparin-binding growth factor 4-II xEFGF-II
Gene Type	protein-coding
Organism	Xenopus laevis(African clawed frog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001085824.1	NP_001079293.1	fibroblast growth factor 4B precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

FGF4 regulates blood and muscle specification in Xenopus laevis.
Isaacs HV, Deconinck AE, Pownall ME
Biology of the cell99(3)165-73(2007 Mar)

derri?re: a TGF-beta family member required for posterior development in Xenopus.
Sun BI, Bush SM, Collins-Racie LA, LaVallie ER, DiBlasio-Smith EA, Wolfman NM, McCoy JM, Sive HL
Development (Cambridge, England)126(7)1467-82(1999 Apr)

Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification.
Isaacs HV, Tannahill D, Slack JM
Development (Cambridge, England)114(3)711-20(1992 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our data indicate that in Xenopus FGF4 is a key organizer-derived signal involved in the process of dorsoventral patterning of the mesoderm.(FGF4)
Title: FGF4 regulates blood and muscle specification in Xenopus laevis.

The following fgf4.S gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the fgf4.S cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OAf00147	NM_001085824.1 Latest version!	Xenopus laevis fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene) S homeolog (fgf4.S), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

fgf4.S ( NM_001085824.1 ) cDNA ORF clone, Xenopus laevis(African clawed frog) -> NP_001079293.1 Xenopus laevis fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene) S homeolog (fgf4.S), mRNA.

Price & Availability↑

CloneID	OAf00147
Clone ID Related Accession (Same CDS sequence)	NM_001085824.1
Accession Version	NM_001085824.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Xenopus laevis(African clawed frog)
Product	fibroblast growth factor 4B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X62594.1. ##Evidence-Data-START## Transcript exon combination :: X62594.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00012419, SAMD00012420 [ECO:0000348] ##Evidence-Data-END##

ATGACTGTTC AATTGGCCCT GGTGCCAATC CTGCTCCTGG GAACGGCTGC CGTTATGGTG 
CACTGCATGC CGTTCTCTTC TTCCCAGAGA AATGACACCC TGGAACGGAG ATGGGAGACC 
CTCTTTTCCA GGTCCATGGC CAGGATCCCG GGGGAAAAAA AGGATATGAG TCGGGAAAGT 
GACTATTTGC TGGGCATCAA GAGACTGCGA CGTCTTTACT GCAACGTGGG CATCGGGTTT 
CATATCCAGG TTTTACCGGA CGGAAGGATA AATGGCATGC ACAACGAAAA TCGATACAGT 
TTACTGGAGA TTTCCCCAGT GGAAGTGGGA GTCGTGAGTT TGTACGGCAT TAAAAGCGCC 
ATGTTTGTTG CTATGAATGC AAAGGGGAAG CTGTATGGAT CAAGATATTT CAACGAGGAA 
TGCAAATTCA AAGAGACACT TCTGCCCAAC AACTATAACG CTTACGAATC CAGGAAATAC 
CCCGGCATGT ACATTGCTCT GGGCAAAAAT GGAAGGACAA AAAAAGGGAA CAGAGTTTCT 
CCGACAATGA CACTGACCCA TTTCTTGCCA CGGATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001079293.1
CDS	11..589
Translation	MTVQLALVPILLLGTAAVMVHCMPFSSSQRNDTLERRWETLFSRSMARIPGEKKDMSRESDYLLGIKRLRRLYCNVGIGFHIQVLPDGRINGMHNENRYSLLEISPVEVGVVSLYGIKSAMFVAMNAKGKLYGSRYFNEECKFKETLLPNNYNAYESRKYPGMYIALGKNGRTKKGNRVSPTMTLTHFLPRI

Target ORF information:

RefSeq Version	NM_001085824.1
Organism	Xenopus laevis(African clawed frog)
Definition	Xenopus laevis fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene) S homeolog (fgf4.S), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001085824.1

ORF Insert Sequence:

ATGACTGTTC AATTGGCCCT GGTGCCAATC CTGCTCCTGG GAACGGCTGC CGTTATGGTG 
CACTGCATGC CGTTCTCTTC TTCCCAGAGA AATGACACCC TGGAACGGAG ATGGGAGACC 
CTCTTTTCCA GGTCCATGGC CAGGATCCCG GGGGAAAAAA AGGATATGAG TCGGGAAAGT 
GACTATTTGC TGGGCATCAA GAGACTGCGA CGTCTTTACT GCAACGTGGG CATCGGGTTT 
CATATCCAGG TTTTACCGGA CGGAAGGATA AATGGCATGC ACAACGAAAA TCGATACAGT 
TTACTGGAGA TTTCCCCAGT GGAAGTGGGA GTCGTGAGTT TGTACGGCAT TAAAAGCGCC 
ATGTTTGTTG CTATGAATGC AAAGGGGAAG CTGTATGGAT CAAGATATTT CAACGAGGAA 
TGCAAATTCA AAGAGACACT TCTGCCCAAC AACTATAACG CTTACGAATC CAGGAAATAC 
CCCGGCATGT ACATTGCTCT GGGCAAAAAT GGAAGGACAA AAAAAGGGAA CAGAGTTTCT 
CCGACAATGA CACTGACCCA TTTCTTGCCA CGGATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

FGF4 regulates blood and muscle specification in Xenopus laevis.
Biology of the cell99(3)165-73(2007 Mar)
Isaacs HV,Deconinck AE,Pownall ME

derri?re: a TGF-beta family member required for posterior development in Xenopus.
Development (Cambridge, England)126(7)1467-82(1999 Apr)
Sun BI,Bush SM,Collins-Racie LA,LaVallie ER,DiBlasio-Smith EA,Wolfman NM,McCoy JM,Sive HL

Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification.
Development (Cambridge, England)114(3)711-20(1992 Mar)
Isaacs HV,Tannahill D,Slack JM