CXCL10 cDNA ORF clone, Sus scrofa(pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	CXCL10
Entrez Gene ID	494019
Full Name	C-X-C motif chemokine ligand 10
Gene Type	protein-coding
Organism	Sus scrofa(pig)
Genome	Chromosome: 8 Map Location: 8\|8

mRNA and Protein(s)

mRNA	Protein	Name
NM_001008691.1	NP_001008691.1	C-X-C motif chemokine 10 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

A SNP in the porcine chemokine (C-X-C motif) ligand 10 gene is associated with blood hemoglobin concentration.
Huang J, Xu N, Pan J
Animal genetics47(1)134-5(2016 Feb)

Pseudorabies viral replication is inhibited by a novel target of miR-21.
Huang J, Ma G, Fu L, Jia H, Zhu M, Li X, Zhao S
Virology456-457319-28(2014 May)

Increase in chemokines CXCL10 and CCL2 in blood from pigs infected with high compared to low virulence African swine fever virus isolates.
Fishbourne E, Hutet E, Abrams C, Cariolet R, Le Potier MF, Takamatsu HH, Dixon LK
Veterinary research4487(2013 Oct)

All three classes of CpG ODNs up-regulate IP-10 gene in pigs.
Dar A, Nichani A, Lai K, Potter A, Gerdts V, Babiuk LA, Mutwiri G
Research in veterinary science88(2)242-50(2010 Apr)

Isolation, sequence analysis and expression profile of a novel porcine gene, CXCL10, differentially expressed in the Longissimus dorsi muscle tissues from Meishan, Meishan x Large White cross and Large White pigs.
Liu GY, Xiong YZ
DNA sequence : the journal of DNA sequencing and mapping18(6)415-22(2007 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a SNP in CXCL10 was significantly associated with percentage of lymphocyte in blood of 20-day-old pigs and with hematocrit and mean red cell volume in blood of 80-day-old pigs
Title: A SNP in the porcine chemokine (C-X-C motif) ligand 10 gene is associated with blood hemoglobin concentration.

Authors identified chemokine (C-X-C motif) ligand 10 (CXCL10), also named interferon-gamma inducible protein-10 (IP-10), as a novel target gene of miR-21.
Title: Pseudorabies viral replication is inhibited by a novel target of miR-21.

CXCL10 protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.
Title: Increase in chemokines CXCL10 and CCL2 in blood from pigs infected with high compared to low virulence African swine fever virus isolates.

These in vitro and in vivo observations suggest that interferon-gamma inducible protein 10 (IP-10) may be a reliable biomarker for immune activity induced by CpG oligodeoxynucleotides in pigs.
Title: All three classes of CpG ODNs up-regulate IP-10 gene in pigs.

The swine CXCL10 gene contains four exons and three introns.
Title: Isolation, sequence analysis and expression profile of a novel porcine gene, CXCL10, differentially expressed in the Longissimus dorsi muscle tissues from Meishan, Meishan x Large White cross and Large White pigs.

The following CXCL10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CXCL10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSe28325	NM_001008691.1 Latest version!	Sus scrofa C-X-C motif chemokine ligand 10 (CXCL10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CXCL10 ( NM_001008691.1 ) cDNA ORF clone, Sus scrofa(pig) -> NP_001008691.1 Sus scrofa C-X-C motif chemokine ligand 10 (CXCL10), mRNA.

Price & Availability↑

CloneID	OSe28325
Clone ID Related Accession (Same CDS sequence)	NM_001008691.1
Accession Version	NM_001008691.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 315bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-28
Organism	Sus scrofa(pig)
Product	C-X-C motif chemokine 10 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY789646.1. ##Evidence-Data-START## Transcript exon combination :: AY789646.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1487420, SAMEA1876824 [ECO:0000350] ##Evidence-Data-END##

ATGAACCAAA GTGCTGTTCT TATTTTCTGC CTTATTCTTC TGACTCTGAG TGGAACTCAA 
GGAATACCTC TCTCCAGAAC TGTTCGCTGT ACCTGCATCA AGATCAGTGA CAGACCTGTT 
AATCCGAGGT CCTTAGAAAA ACTTGAAATG ATTCCTGCAA GTCAATCTTG CCCACATGTT 
GAGATCATTG CCACAATGAA AAAGAATGGG GAGAAAAGAT GTCTGAATCC AGAGTCTAAG 
ACCATCAAGA ATTTACTGAA AGCAATTAGC AAAGAAAGGT CTAAAAGATC TCCTCGAACA 
CAGAGAGAAG CATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008691.1
CDS	69..383
Translation	MNQSAVLIFCLILLTLSGTQGIPLSRTVRCTCIKISDRPVNPRSLEKLEMIPASQSCPHVEIIATMKKNGEKRCLNPESKTIKNLLKAISKERSKRSPRTQREA

Target ORF information:

RefSeq Version	NM_001008691.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa C-X-C motif chemokine ligand 10 (CXCL10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008691.1

ORF Insert Sequence:

ATGAACCAAA GTGCTGTTCT TATTTTCTGC CTTATTCTTC TGACTCTGAG TGGAACTCAA 
GGAATACCTC TCTCCAGAAC TGTTCGCTGT ACCTGCATCA AGATCAGTGA CAGACCTGTT 
AATCCGAGGT CCTTAGAAAA ACTTGAAATG ATTCCTGCAA GTCAATCTTG CCCACATGTT 
GAGATCATTG CCACAATGAA AAAGAATGGG GAGAAAAGAT GTCTGAATCC AGAGTCTAAG 
ACCATCAAGA ATTTACTGAA AGCAATTAGC AAAGAAAGGT CTAAAAGATC TCCTCGAACA 
CAGAGAGAAG CATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A SNP in the porcine chemokine (C-X-C motif) ligand 10 gene is associated with blood hemoglobin concentration.
Animal genetics47(1)134-5(2016 Feb)
Huang J,Xu N,Pan J

Pseudorabies viral replication is inhibited by a novel target of miR-21.
Virology456-457319-28(2014 May)
Huang J,Ma G,Fu L,Jia H,Zhu M,Li X,Zhao S

Increase in chemokines CXCL10 and CCL2 in blood from pigs infected with high compared to low virulence African swine fever virus isolates.
Veterinary research4487(2013 Oct)
Fishbourne E,Hutet E,Abrams C,Cariolet R,Le Potier MF,Takamatsu HH,Dixon LK

All three classes of CpG ODNs up-regulate IP-10 gene in pigs.
Research in veterinary science88(2)242-50(2010 Apr)
Dar A,Nichani A,Lai K,Potter A,Gerdts V,Babiuk LA,Mutwiri G

Isolation, sequence analysis and expression profile of a novel porcine gene, CXCL10, differentially expressed in the Longissimus dorsi muscle tissues from Meishan, Meishan x Large White cross and Large White pigs.
DNA sequence : the journal of DNA sequencing and mapping18(6)415-22(2007 Dec)
Liu GY,Xiong YZ