CASP1 cDNA ORF clone, Sus scrofa(pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	CASP1
Entrez Gene ID	397319
Full Name	caspase 1, apoptosis-related cysteine peptidase
Gene Type	protein-coding
Organism	Sus scrofa(pig)

mRNA and Protein(s)

mRNA	Protein	Name
NM_214162.1	NP_999327.1	caspase-1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Temporal Changes in Caspase-1 and Caspase-8 Activities Following Brain Hypoxia With and Without Src kinase Inhibition in a Piglet Animal Model.
Angelis D, Font?nez Nieves TD, Delivoria-Papadopoulos M
Neurochemical research40(11)2270-9(2015 Nov)

The role of SRC kinase in the caspase-1 pathway after hypoxia in the brain of newborn piglets.
Angelis D, Font?nez-Nieves TD, Delivoria-Papadopoulos M
Neurochemical research39(11)2118-26(2014 Nov)

Endometrial caspase 1 and interleukin-18 expression during the estrous cycle and peri-implantation period of porcine pregnancy and response to early exogenous estrogen administration.
Ashworth MD, Ross JW, Stein DR, White FJ, Desilva UW, Geisert RD
Reproductive biology and endocrinology : RB&E833(2010 Apr)

PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries.
Uenishi H, Eguchi T, Suzuki K, Sawazaki T, Toki D, Shinkai H, Okumura N, Hamasima N, Awata T
Nucleic acids research32(Database issue)D484-8(2004 Jan)

Molecular cloning of porcine interleukin-1beta converting enzyme and differential gene expression of IL-1beta converting enzyme, IL-1beta, and IL-18 in porcine alveolar macrophages.
Muneta Y, Shimoji Y, Yokomizo Y, Mori Y
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research19(11)1289-96(1999 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

mmediately after hypoxia C8 and C1 follow a similar pattern of increase while long term this appears to dissociate
Title: Temporal Changes in Caspase-1 and Caspase-8 Activities Following Brain Hypoxia With and Without Src kinase Inhibition in a Piglet Animal Model.

Src kinase mediates hypoxia-induced caspase-1 activation in the cerebral cortex of newborn piglets
Title: The role of SRC kinase in the caspase-1 pathway after hypoxia in the brain of newborn piglets.

endometrial expression of CASP1 and IL18 associated with pregnancy establishment; alteration of CASP1 and IL18 following premature exposure of uterus to estrogen during early pregnancy may contribute to conceptus loss between Days 15 to 18 of pregnancy
Title: Endometrial caspase 1 and interleukin-18 expression during the estrous cycle and peri-implantation period of porcine pregnancy and response to early exogenous estrogen administration.

The following CASP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CASP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSe00537	NM_214162.1 Latest version!	Sus scrofa caspase 1, apoptosis-related cysteine peptidase (CASP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CASP1 ( NM_214162.1 ) cDNA ORF clone, Sus scrofa(pig) -> NP_999327.1 Sus scrofa caspase 1, apoptosis-related cysteine peptidase (CASP1), mRNA.

Price & Availability↑

CloneID	OSe00537
Clone ID Related Accession (Same CDS sequence)	NM_214162.1
Accession Version	NM_214162.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1215bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Sus scrofa(pig)
Product	caspase-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB027296.1. ##Evidence-Data-START## Transcript exon combination :: AB027296.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02584787 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGATA AGGTGCTGAA GGAGAAGAGG AGGCTGTTTG TCCGTTCAGT GGCCATGGGT 
ACGATCAATG GCCTCTTGGA TGAACTATTA GAGACCAGAG TCCTGAACCA GGAGGAGGTG 
GAGATAGTAA GAGGTGAAAA CGCTACAGTT ATGGATAAGG CCCGAGCTTT GATTGACTCT 
GTTATTCGGA AAGGGCCCCA GGCATGCCAA ATTTGCATCA ATCATATTTG TGGAGACGAC 
CCCCACCTTG CAGGAGTCCT CGAACTCTCC ACAGGTTCAC AATCTGGAAA ATGCCTTACT 
GTACAAGAAT CCCAGGCGGT GGTTCCTCCT TTCCCAGCCC CTCAGACAGT ACAAGACAAC 
CCAGTTAAGC CTGCGTCTTC AGAGCCAAGA GGGAGCCTCA AGCTTTGCCC CCCAGACATA 
GCCCAAAGGC TATGGAAAGA AAAGTCAGCA GAGATTTACC CAATAATGGG AAAATCAATT 
CGCACACGCC TTGCCCTCAT AATCTGCAAC ACAGAGTTTG AAAATCTTCC CAGGAGAGAT 
GGTGCTGATG TTGATATTAG AGACATGAAG ATACTACTAG AAGATTTGGG TTACAGTGTG 
GATGTTAGAG AAAATCTCAC CGCTTCGGAC ATGGCTATAG AGCTGAAGGC ATTTGCTGCC 
CGCCCAGAGC ACAAGTCCTC TGATAGTACT TTTCTGGTGC TCATGTCTCA TGGAATCCAG 
GCTGGCATTT GTGGGAAGAA ATACTCCGAA GAAGTCCCAG ATGTATTAGA AGTCAACACC 
GTCTTTCAGA TTTTGAACAC CTTGAACTGT CCAAGTTTGA AGGACAAACC CAAGGTGATC 
ATTATCCAGG CTTGCCGTGG TGAGAAGCAA GGGGTCGTAT GGATAAAAGA TTCAGTAGGA 
CCTTCTGGAA ATTCCTCCTT ACTGGCTGCA GAAGATTTTG AGTATGATGC CATTAAGAAA 
GCCCACATAG AAAAAGATTT TATTGCTTTC TGTTCTTCAA CACCAGATAA TGTTTCTTGG 
CGACATCCCT TATTGGGCTC TCTTTTTATT ATTAAACTCA TCAAAATTTT GCAAGAACAT 
GCCTGGTCCT GTGGCCTGGA GGAAATTTTT CGAAAGGTTC GATTTTCATT TGAGCTGGCA 
GATGGTAGGG CGCAGATGCC CACTGCCGAA AGAGTGACTT TGACTAGATC TTTTTATCTC 
TTCCCAGGAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_999327.1
CDS	1..1215
Translation	MADKVLKEKRRLFVRSVAMGTINGLLDELLETRVLNQEEVEIVRGENATVMDKARALIDSVIRKGPQACQICINHICGDDPHLAGVLELSTGSQSGKCLTVQESQAVVPPFPAPQTVQDNPVKPASSEPRGSLKLCPPDIAQRLWKEKSAEIYPIMGKSIRTRLALIICNTEFENLPRRDGADVDIRDMKILLEDLGYSVDVRENLTASDMAIELKAFAARPEHKSSDSTFLVLMSHGIQAGICGKKYSEEVPDVLEVNTVFQILNTLNCPSLKDKPKVIIIQACRGEKQGVVWIKDSVGPSGNSSLLAAEDFEYDAIKKAHIEKDFIAFCSSTPDNVSWRHPLLGSLFIIKLIKILQEHAWSCGLEEIFRKVRFSFELADGRAQMPTAERVTLTRSFYLFPGH

Target ORF information:

RefSeq Version	NM_214162.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa caspase 1, apoptosis-related cysteine peptidase (CASP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_214162.1

ORF Insert Sequence:

ATGGCCGATA AGGTGCTGAA GGAGAAGAGG AGGCTGTTTG TCCGTTCAGT GGCCATGGGT 
ACGATCAATG GCCTCTTGGA TGAACTATTA GAGACCAGAG TCCTGAACCA GGAGGAGGTG 
GAGATAGTAA GAGGTGAAAA CGCTACAGTT ATGGATAAGG CCCGAGCTTT GATTGACTCT 
GTTATTCGGA AAGGGCCCCA GGCATGCCAA ATTTGCATCA ATCATATTTG TGGAGACGAC 
CCCCACCTTG CAGGAGTCCT CGAACTCTCC ACAGGTTCAC AATCTGGAAA ATGCCTTACT 
GTACAAGAAT CCCAGGCGGT GGTTCCTCCT TTCCCAGCCC CTCAGACAGT ACAAGACAAC 
CCAGTTAAGC CTGCGTCTTC AGAGCCAAGA GGGAGCCTCA AGCTTTGCCC CCCAGACATA 
GCCCAAAGGC TATGGAAAGA AAAGTCAGCA GAGATTTACC CAATAATGGG AAAATCAATT 
CGCACACGCC TTGCCCTCAT AATCTGCAAC ACAGAGTTTG AAAATCTTCC CAGGAGAGAT 
GGTGCTGATG TTGATATTAG AGACATGAAG ATACTACTAG AAGATTTGGG TTACAGTGTG 
GATGTTAGAG AAAATCTCAC CGCTTCGGAC ATGGCTATAG AGCTGAAGGC ATTTGCTGCC 
CGCCCAGAGC ACAAGTCCTC TGATAGTACT TTTCTGGTGC TCATGTCTCA TGGAATCCAG 
GCTGGCATTT GTGGGAAGAA ATACTCCGAA GAAGTCCCAG ATGTATTAGA AGTCAACACC 
GTCTTTCAGA TTTTGAACAC CTTGAACTGT CCAAGTTTGA AGGACAAACC CAAGGTGATC 
ATTATCCAGG CTTGCCGTGG TGAGAAGCAA GGGGTCGTAT GGATAAAAGA TTCAGTAGGA 
CCTTCTGGAA ATTCCTCCTT ACTGGCTGCA GAAGATTTTG AGTATGATGC CATTAAGAAA 
GCCCACATAG AAAAAGATTT TATTGCTTTC TGTTCTTCAA CACCAGATAA TGTTTCTTGG 
CGACATCCCT TATTGGGCTC TCTTTTTATT ATTAAACTCA TCAAAATTTT GCAAGAACAT 
GCCTGGTCCT GTGGCCTGGA GGAAATTTTT CGAAAGGTTC GATTTTCATT TGAGCTGGCA 
GATGGTAGGG CGCAGATGCC CACTGCCGAA AGAGTGACTT TGACTAGATC TTTTTATCTC 
TTCCCAGGAC ATTAA