Slit3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slit3
Entrez Gene ID	83467
Full Name	slit guidance ligand 3
Synonyms	Megf5
General protein information	Preferred Names slit guidance ligand 3 Names slit homolog 3 protein multiple EGF-like domains protein 5 multiple epidermal growth factor-like domains 5 multiple epidermal growth factor-like domains protein 5 slit-3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q12
Summary	localized to mitochondria; has less conservation with Drosophila slit than family members slit1 and slit2; may play a role in neurogenesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031321.1	NP_112611.1	slit homolog 3 protein precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SLIT3	NP_001178379.1
Gallus gallus (chicken)	SLIT3	NP_001183971.1
Pan troglodytes (chimpanzee)	SLIT3	XP_003311018.2
Xenopus tropicalis (tropical clawed frog)	slit3	NP_001072738.1
Homo sapiens (human)	SLIT3	NP_001258875.1
Rattus norvegicus (Norway rat)	Slit3	NP_112611.1
Danio rerio (zebrafish)	slit3	NP_571811.2
	LOC703950	XP_002808486.1
Canis lupus familiaris (dog)	SLIT3	XP_005619283.1
Mus musculus (house mouse)	Slit3	NP_035542.2

Gene Ontology
Bibliography

Related articles in PubMed

Down-regulation of N-deacetylase-N-sulfotransferase-1 signaling in the developing diaphragmatic vasculature of nitrofen-induced congenital diaphragmatic hernia.
Takahashi T, Friedmacher F, Zimmer J, Puri P
Journal of pediatric surgery52(6)1035-1039(2017 Jun)

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.
Mommersteeg MT, Yeh ML, Parnavelas JG, Andrews WD
Cardiovascular research106(1)55-66(2015 Apr)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

Repulsive axon guidance molecule Slit3 is a novel angiogenic factor.
Zhang B, Dietrich UM, Geng JG, Bicknell R, Esko JD, Wang L
Blood114(19)4300-9(2009 Nov)

SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium.
Marlow R, Strickland P, Lee JS, Wu X, Pebenito M, Binnewies M, Le EK, Moran A, Macias H, Cardiff RD, Sukumar S, Hinck L
Cancer research68(19)7819-27(2008 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Relative mRNA expression of Ndst1 and Slit3 was significantly decreased in pleuroperitoneal folds, developing diaphragms and fully muscularized diaphragms, and endothelial cells within the diaphragmatic vasculature of nitrofen-exposed fetuses compared to controls.
Title: Down-regulation of N-deacetylase-N-sulfotransferase-1 signaling in the developing diaphragmatic vasculature of nitrofen-induced congenital diaphragmatic hernia.

The difference in expression pattern of Slit family mRNA in the neurons during peripheral nerve regeneration suggests that it plays a different role in axonal regeneration after axotomy of peripheral nerves
Title: mRNA expression changes of slit proteins following peripheral nerve injury in the rat model.

The following Slit3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slit3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42666	NM_031321.1 Latest version!	Rattus norvegicus slit guidance ligand 3 (Slit3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$1119.30 $1599.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slit3 ( NM_031321.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112611.1 Rattus norvegicus slit guidance ligand 3 (Slit3), mRNA.

Price & Availability↑

CloneID	ORa42666
Clone ID Related Accession (Same CDS sequence)	NM_031321.1
Accession Version	NM_031321.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4572bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Rattus norvegicus(Norway rat)
Product	slit homolog 3 protein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB011531.1. On Jan 12, 2005 this sequence version replaced XM_346391.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB011531.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689595 [ECO:0000348] ##Evidence-Data-END##

ATGGCCCCCG GGCGGACCGG GGCCGGCGCC GCTGTGCGCG CCCGCCTGGC GCTGGCCTTG 
GCGCTGGCGA GCATCCTGAG CGGACCCCCC GCTGCTGCCT GCCCCACCAA GTGTACCTGC 
TCCGCCGCTA GCGTGGACTG CCACGGGCTG GGCCTGCGCG CCGTTCCCCG GGGCATCCCC 
CGCAACGCTG AGCGCCTTGA CCTGGACAGA AATAACATCA CCAGGATCAC CAAAATGGAC 
TTCACCGGCT TGAAGAATCT CCGAGTCTTG CATCTGGAAG ACAATCAGGT CAGCGTCATC 
GAGAGAGGCG CCTTCCAGGA TCTGAAGCAG CTGGAGCGAT TACGTCTGAA CAAGAACAAG 
CTCCAGGTCC TTCCAGAATT ACTTTTCCAG AGCACACCGA AGCTCACCAG ACTAGATCTG 
AGCGAAAACC AGATCCAGGG CATCCCGAGG AAGGCGTTCA GGGGCGTCAC GGGCGTGAAG 
AACCTGCAAC TGGACAATAA CCACATCAGC TGCATTGAAG ATGGAGCCTT CCGAGCGCTG 
CGCGATTTGG AGATCCTCAC CCTTAACAAC AACAACATCA GCCGTATCCT GGTCACCAGC 
TTCAACCACA TGCCGAAGAT CCGGACCCTG CGTCTCCACT CCAACCACCT GTACTGTGAT 
TGTCACTTGG CCTGGCTCTC AGACTGGCTG CGACAGCGGC GGACCATTGG CCAGTTCACC 
CTCTGCATGG CGCCCGTGCA CCTGAGAGGC TTCAGTGTAG CAGACGTGCA GAAGAAGGAG 
TATGTGTGTC CAGGTCCCCA CTCAGAGGCT CCAGCCTGCA ATGCCAACTC CCTCTCCTGC 
CCTTCTGCCT GCTCATGCAG TAATAACATT GTAGACTGCC GTGGGAAGGG ACTGACTGAG 
ATCCCTGCCA ACCTGCCGGA GGGCATCGTG GAAATACGCC TAGAACAGAA CTCCATCAAA 
TCCATTCCTG CAGGAGCTTT CATCCAGTAC AAAAAACTGA AGCGAATAGA CATCAGCAAG 
AATCAGATAT CGGACATTGC TCCAGATGCC TTCCAGGGCC TGAAATCACT CACGTCGCTG 
GTGCTCTATG GGAACAAGAT CACAGAGATT CCCAAAGGAC TGTTTGACGG GCTGGTGTCC 
CTGCAGCTGC TCCTCCTCAA TGCCAACAAG ATCAACTGCC TGCGGGTAAA CACCTTCCAG 
GACCTACAGA ACCTCAATCT GCTCTCTCTG TATGACAACA AGTTGCAGAC TATCAGCAAA 
GGGCTCTTTG CTCCGCTGCA GTCCATCCAG ACCCTCCACT TAGCTCAAAA CCCGTTTGTT 
TGCGACTGCC ACTTGAAGTG GTTGGCCGAC TACCTCCAGG ACAACCCCAT TGAGACGAGC 
GGGGCCCGCT GCAGCAGCCC ACGCCGGCTG GCCAACAAGC GCATCAGCCA GATCAAAAGC 
AAGAAGTTCC GCTGCTCAGG CTCGGAGGAT TATCGCAACA GATTCAGCAG CGAGTGCTTC 
ATGGACCTAG TGTGCCCCGA GAAGTGCCGT TGTGAGGGCA CCATTGTGGA CTGCTCCAAC 
CAGAAGCTCT CCCGCATCCC GAGCCACCTC CCTGAATATA CCACTGACCT GCGACTGAAC 
GACAATGACA TCGCTGTGCT GGAGGCCACT GGGATCTTCA AGAAGTTGCC CAACCTGAGG 
AAAATAAACT TGAGCAATAA TAGGATCAAG GAGGTGCGGG AGGGTGCGTT TGATGGAGCG 
GCAGGCGTGC AGGAACTGAT GCTGACGGGG AACCAGCTGG AGACCATGCA CGGACGCATG 
TTCCGGGGCC TCAGCGGCCT GAAGACACTG ATGTTAAGGA GCAACCTGAT CAGCTGCGTA 
AACAATGACA CCTTCGCTGG CCTAAGCTCT GTGAGACTGC TGTCCCTCTA TGACAATCGG 
ATCACCACCA TCAGCCCTGG AGCCTTCACC ACGCTCGTCT CCCTGTCCAC CATAAACCTC 
TTGTCTAACC CTTTCAACTG CAACTGTCAC ATGGCCTGGC TCGGCCGGTG GCTGAGGAAA 
CGCCGCATCG TAAGCGGGAA CCCCAGATGT CAGAAGCCCT TTTTCCTCAA GGAGATTCCT 
ATCCAAGATG TGGCCATCCA GGACTTCACC TGTGAAGGCA ATGAAGAGAA CAGCTGTCAG 
CTGAGTCCAC GCTGCCCCGA GCAGTGTACC TGTGTGGAGA CAGTGGTGCG ATGCAGCAAC 
AGGGGTCTCC ACACCCTCCC CAAGGGCATG CCAAAGGACG TGACTGAACT GTACCTGGAA 
GGAAATCATT TAACGGCGGT GCCCAAAGAA TTGTCCACCT TCCGACAGCT GACACTAATT 
GACCTGAGCA ACAACAGCAT CAGTATGCTG ACCAATCACA CCTTCAGCAA CATGTCCCAC 
CTCTCCACAC TGATCCTGAG CTACAACCGG CTGAGATGCA TCCCGGTCCA TGCCTTCAAC 
GGGCTAAGGT CACTCCGAGT GCTAACCCTC CATGGCAATG ACATTTCCAG TGTTCCTGAA 
GGCTCCTTCA ATGATCTGAC GTCCCTCTCC CACCTGGCCC TGGGAATCAA CCCTCTCCAC 
TGTGACTGCA GTCTGCGTTG GTTATCAGAG TGGATAAAGG CTGGGTACAA GGAGCCTGGC 
ATTGCCAGAT GCAGTAGCCC CGAGTCCATG GCAGACAGAC TCCTGCTCAC CACCCCCACC 
CACAGGTTCC AGTGCAAAGG GCCAGTGGAC ATTAACATCG TGGCCAAGTG CAACGCCTGC 
CTCTCTAGCC CATGCAAGAA CAACGGCACT TGCAGCCAGG ATCCGGTGGA GCAGTACCGC 
TGTACCTGCC CTTACAGCTA CAAGGGCAAG GACTGCACCG TGCCCATCAA CACCTGCGTC 
CAGAACCCCT GTCAGCACGG AGGCACCTGT CACCTCAGTG AGAGCCACAG AGATGGGTTC 
AGCTGCTCCT GCCCCCTGGG CTTTGAGGGA CAGCGGTGTG AGATCAACCC AGATGACTGT 
GAGGATAACG ACTGTGAAAA CAGCGCCACC TGTGTGGACG GGATCAACAA CTACGCATGC 
GTGTGCCCGC CGAACTACAC AGGGGAGCTG TGTGATGAGG TGATTGACTA CTGCGTGCCC 
GAGATGAACC TCTGTCAGCA CGAGGCCAAG TGCATCTCCC TGGACAAAGG ATTCAGGTGC 
GAATGTGTCC CTGGCTACAG TGGAAAGCTG TGCGAGACAG ACAACGATGA CTGTGTGGCT 
CACAAGTGTC GCCACGGAGC CCAGTGTGTG GACGCGGTCA ATGGCTACAC GTGCATCTGC 
CCCCAGGGCT TCAGCGGGCT CTTCTGTGAG CACCCCCCAC CCATGGTTCT GCTACAGACC 
AGCCCCTGTG ACCAGTACGA GTGCCAGAAT GGGGCGCAGT GCATCGTGGT ACAGCAGGAG 
CCCACTTGCC GCTGTCCCCC AGGCTTCGCT GGGCCCAGGT GTGAGAAGCT CATCACTGTG 
AATTTCGTGG GCAAGGACTC CTATGTGGAA CTGGCCTCTG CCAAGGTCCG GCCCCAGGCC 
AACATCTCCC TGCAGGTGGC CACTGACAAG GACAACGGCA TCCTTCTTTA CAAGGGAGAC 
AACGACCCCC TGGCACTGGA GCTGTACCAG GGTCACGTGA GGCTGGTGTA TGACAGCCTG 
AGCTCCCCTC CGACCACGGT GTACAGTGTG GAGACGGTGA ATGATGGCCA GTTTCACAGT 
GTGGAGCTGG TGATGCTAAA CCAGACCCTG AACCTGGTGG TAGACAAAGG AGCCCCCAAG 
AGCCTGGGGA AGCTCCAGAA GCAGCCAGCA GTGGGCATCA ACAGTCCCCT CTATCTTGGA 
GGCATCCCCA CGTCTACAGG CCTCTCAGCC TTACGCCAGG GTGCAGACAG GCCGCTGGGC 
GGCTTCCACG GCTGTATACA CGAAGTGCGC ATCAACAACG AGTTGCAGGA TTTCAAAGCC 
CTCCCACCCC AGTCCCTGGG GGTCTCTCCC GGCTGCAAAT CCTGCACTGT GTGTCGTCAC 
GGCCTGTGTC GTTCCGTGGA GAAGGACAGC GTAGTGTGTG AGTGCCATCC GGGATGGACT 
GGTCCACTGT GTGATCAGGA AGCCCAGGAC CCCTGCCTTG GTCACAGCTG CAGCCATGGG 
ACATGCGTGG CGACTGGCAA CTCATATGTG TGCAAGTGTG CCGAGGGCTA TGAGGGACCT 
TTGTGTGACC AGAAGAATGA CTCTGCCAAT GCCTGCTCAG CCTTCAAGTG CCACCACGGG 
CAGTGCCACA TCTCAGATCG AGGGGAGCCC TATTGCCTGT GCCAGCCTGG CTTCAGTGGC 
AATCACTGTG AGCAAGAGAA TCCATGTTTG GGAGAGATAG TCCGTGAAGC CATCCGCCGC 
CAGAAAGATT ATGCCTCCTG TGCCACAGCA TCCAAGGTGC CCATCATGGT ATGCCGCGGG 
GGCTGCGGGA GCCAATGCTG CCAGCCGATT CGGAGCAAGC GGCGGAAATA CGTCTTCCAG 
TGCACTGACG GCTCCTCGTT CGTGGAAGAG GTGGAGAGAC ACTTGGAATG TGGCTGTCGT 
GAGTGTTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112611.1
CDS	292..4863
Translation	MAPGRTGAGAAVRARLALALALASILSGPPAAACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFTGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGVTGVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTIGQFTLCMAPVHLRGFSVADVQKKEYVCPGPHSEAPACNANSLSCPSACSCSNNIVDCRGKGLTEIPANLPEGIVEIRLEQNSIKSIPAGAFIQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRNRFSSECFMDLVCPEKCRCEGTIVDCSNQKLSRIPSHLPEYTTDLRLNDNDIAVLEATGIFKKLPNLRKINLSNNRIKEVREGAFDGAAGVQELMLTGNQLETMHGRMFRGLSGLKTLMLRSNLISCVNNDTFAGLSSVRLLSLYDNRITTISPGAFTTLVSLSTINLLSNPFNCNCHMAWLGRWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCEGNEENSCQLSPRCPEQCTCVETVVRCSNRGLHTLPKGMPKDVTELYLEGNHLTAVPKELSTFRQLTLIDLSNNSISMLTNHTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGINPLHCDCSLRWLSEWIKAGYKEPGIARCSSPESMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTCSQDPVEQYRCTCPYSYKGKDCTVPINTCVQNPCQHGGTCHLSESHRDGFSCSCPLGFEGQRCEINPDDCEDNDCENSATCVDGINNYACVCPPNYTGELCDEVIDYCVPEMNLCQHEAKCISLDKGFRCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDAVNGYTCICPQGFSGLFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVMLNQTLNLVVDKGAPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGADRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCRHGLCRSVEKDSVVCECHPGWTGPLCDQEAQDPCLGHSCSHGTCVATGNSYVCKCAEGYEGPLCDQKNDSANACSAFKCHHGQCHISDRGEPYCLCQPGFSGNHCEQENPCLGEIVREAIRRQKDYASCATASKVPIMVCRGGCGSQCCQPIRSKRRKYVFQCTDGSSFVEEVERHLECGCRECS

Target ORF information:

RefSeq Version	NM_031321.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus slit guidance ligand 3 (Slit3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031321.1

ORF Insert Sequence:

ATGGCCCCCG GGCGGACCGG GGCCGGCGCC GCTGTGCGCG CCCGCCTGGC GCTGGCCTTG 
GCGCTGGCGA GCATCCTGAG CGGACCCCCC GCTGCTGCCT GCCCCACCAA GTGTACCTGC 
TCCGCCGCTA GCGTGGACTG CCACGGGCTG GGCCTGCGCG CCGTTCCCCG GGGCATCCCC 
CGCAACGCTG AGCGCCTTGA CCTGGACAGA AATAACATCA CCAGGATCAC CAAAATGGAC 
TTCACCGGCT TGAAGAATCT CCGAGTCTTG CATCTGGAAG ACAATCAGGT CAGCGTCATC 
GAGAGAGGCG CCTTCCAGGA TCTGAAGCAG CTGGAGCGAT TACGTCTGAA CAAGAACAAG 
CTCCAGGTCC TTCCAGAATT ACTTTTCCAG AGCACACCGA AGCTCACCAG ACTAGATCTG 
AGCGAAAACC AGATCCAGGG CATCCCGAGG AAGGCGTTCA GGGGCGTCAC GGGCGTGAAG 
AACCTGCAAC TGGACAATAA CCACATCAGC TGCATTGAAG ATGGAGCCTT CCGAGCGCTG 
CGCGATTTGG AGATCCTCAC CCTTAACAAC AACAACATCA GCCGTATCCT GGTCACCAGC 
TTCAACCACA TGCCGAAGAT CCGGACCCTG CGTCTCCACT CCAACCACCT GTACTGTGAT 
TGTCACTTGG CCTGGCTCTC AGACTGGCTG CGACAGCGGC GGACCATTGG CCAGTTCACC 
CTCTGCATGG CGCCCGTGCA CCTGAGAGGC TTCAGTGTAG CAGACGTGCA GAAGAAGGAG 
TATGTGTGTC CAGGTCCCCA CTCAGAGGCT CCAGCCTGCA ATGCCAACTC CCTCTCCTGC 
CCTTCTGCCT GCTCATGCAG TAATAACATT GTAGACTGCC GTGGGAAGGG ACTGACTGAG 
ATCCCTGCCA ACCTGCCGGA GGGCATCGTG GAAATACGCC TAGAACAGAA CTCCATCAAA 
TCCATTCCTG CAGGAGCTTT CATCCAGTAC AAAAAACTGA AGCGAATAGA CATCAGCAAG 
AATCAGATAT CGGACATTGC TCCAGATGCC TTCCAGGGCC TGAAATCACT CACGTCGCTG 
GTGCTCTATG GGAACAAGAT CACAGAGATT CCCAAAGGAC TGTTTGACGG GCTGGTGTCC 
CTGCAGCTGC TCCTCCTCAA TGCCAACAAG ATCAACTGCC TGCGGGTAAA CACCTTCCAG 
GACCTACAGA ACCTCAATCT GCTCTCTCTG TATGACAACA AGTTGCAGAC TATCAGCAAA 
GGGCTCTTTG CTCCGCTGCA GTCCATCCAG ACCCTCCACT TAGCTCAAAA CCCGTTTGTT 
TGCGACTGCC ACTTGAAGTG GTTGGCCGAC TACCTCCAGG ACAACCCCAT TGAGACGAGC 
GGGGCCCGCT GCAGCAGCCC ACGCCGGCTG GCCAACAAGC GCATCAGCCA GATCAAAAGC 
AAGAAGTTCC GCTGCTCAGG CTCGGAGGAT TATCGCAACA GATTCAGCAG CGAGTGCTTC 
ATGGACCTAG TGTGCCCCGA GAAGTGCCGT TGTGAGGGCA CCATTGTGGA CTGCTCCAAC 
CAGAAGCTCT CCCGCATCCC GAGCCACCTC CCTGAATATA CCACTGACCT GCGACTGAAC 
GACAATGACA TCGCTGTGCT GGAGGCCACT GGGATCTTCA AGAAGTTGCC CAACCTGAGG 
AAAATAAACT TGAGCAATAA TAGGATCAAG GAGGTGCGGG AGGGTGCGTT TGATGGAGCG 
GCAGGCGTGC AGGAACTGAT GCTGACGGGG AACCAGCTGG AGACCATGCA CGGACGCATG 
TTCCGGGGCC TCAGCGGCCT GAAGACACTG ATGTTAAGGA GCAACCTGAT CAGCTGCGTA 
AACAATGACA CCTTCGCTGG CCTAAGCTCT GTGAGACTGC TGTCCCTCTA TGACAATCGG 
ATCACCACCA TCAGCCCTGG AGCCTTCACC ACGCTCGTCT CCCTGTCCAC CATAAACCTC 
TTGTCTAACC CTTTCAACTG CAACTGTCAC ATGGCCTGGC TCGGCCGGTG GCTGAGGAAA 
CGCCGCATCG TAAGCGGGAA CCCCAGATGT CAGAAGCCCT TTTTCCTCAA GGAGATTCCT 
ATCCAAGATG TGGCCATCCA GGACTTCACC TGTGAAGGCA ATGAAGAGAA CAGCTGTCAG 
CTGAGTCCAC GCTGCCCCGA GCAGTGTACC TGTGTGGAGA CAGTGGTGCG ATGCAGCAAC 
AGGGGTCTCC ACACCCTCCC CAAGGGCATG CCAAAGGACG TGACTGAACT GTACCTGGAA 
GGAAATCATT TAACGGCGGT GCCCAAAGAA TTGTCCACCT TCCGACAGCT GACACTAATT 
GACCTGAGCA ACAACAGCAT CAGTATGCTG ACCAATCACA CCTTCAGCAA CATGTCCCAC 
CTCTCCACAC TGATCCTGAG CTACAACCGG CTGAGATGCA TCCCGGTCCA TGCCTTCAAC 
GGGCTAAGGT CACTCCGAGT GCTAACCCTC CATGGCAATG ACATTTCCAG TGTTCCTGAA 
GGCTCCTTCA ATGATCTGAC GTCCCTCTCC CACCTGGCCC TGGGAATCAA CCCTCTCCAC 
TGTGACTGCA GTCTGCGTTG GTTATCAGAG TGGATAAAGG CTGGGTACAA GGAGCCTGGC 
ATTGCCAGAT GCAGTAGCCC CGAGTCCATG GCAGACAGAC TCCTGCTCAC CACCCCCACC 
CACAGGTTCC AGTGCAAAGG GCCAGTGGAC ATTAACATCG TGGCCAAGTG CAACGCCTGC 
CTCTCTAGCC CATGCAAGAA CAACGGCACT TGCAGCCAGG ATCCGGTGGA GCAGTACCGC 
TGTACCTGCC CTTACAGCTA CAAGGGCAAG GACTGCACCG TGCCCATCAA CACCTGCGTC 
CAGAACCCCT GTCAGCACGG AGGCACCTGT CACCTCAGTG AGAGCCACAG AGATGGGTTC 
AGCTGCTCCT GCCCCCTGGG CTTTGAGGGA CAGCGGTGTG AGATCAACCC AGATGACTGT 
GAGGATAACG ACTGTGAAAA CAGCGCCACC TGTGTGGACG GGATCAACAA CTACGCATGC 
GTGTGCCCGC CGAACTACAC AGGGGAGCTG TGTGATGAGG TGATTGACTA CTGCGTGCCC 
GAGATGAACC TCTGTCAGCA CGAGGCCAAG TGCATCTCCC TGGACAAAGG ATTCAGGTGC 
GAATGTGTCC CTGGCTACAG TGGAAAGCTG TGCGAGACAG ACAACGATGA CTGTGTGGCT 
CACAAGTGTC GCCACGGAGC CCAGTGTGTG GACGCGGTCA ATGGCTACAC GTGCATCTGC 
CCCCAGGGCT TCAGCGGGCT CTTCTGTGAG CACCCCCCAC CCATGGTTCT GCTACAGACC 
AGCCCCTGTG ACCAGTACGA GTGCCAGAAT GGGGCGCAGT GCATCGTGGT ACAGCAGGAG 
CCCACTTGCC GCTGTCCCCC AGGCTTCGCT GGGCCCAGGT GTGAGAAGCT CATCACTGTG 
AATTTCGTGG GCAAGGACTC CTATGTGGAA CTGGCCTCTG CCAAGGTCCG GCCCCAGGCC 
AACATCTCCC TGCAGGTGGC CACTGACAAG GACAACGGCA TCCTTCTTTA CAAGGGAGAC 
AACGACCCCC TGGCACTGGA GCTGTACCAG GGTCACGTGA GGCTGGTGTA TGACAGCCTG 
AGCTCCCCTC CGACCACGGT GTACAGTGTG GAGACGGTGA ATGATGGCCA GTTTCACAGT 
GTGGAGCTGG TGATGCTAAA CCAGACCCTG AACCTGGTGG TAGACAAAGG AGCCCCCAAG 
AGCCTGGGGA AGCTCCAGAA GCAGCCAGCA GTGGGCATCA ACAGTCCCCT CTATCTTGGA 
GGCATCCCCA CGTCTACAGG CCTCTCAGCC TTACGCCAGG GTGCAGACAG GCCGCTGGGC 
GGCTTCCACG GCTGTATACA CGAAGTGCGC ATCAACAACG AGTTGCAGGA TTTCAAAGCC 
CTCCCACCCC AGTCCCTGGG GGTCTCTCCC GGCTGCAAAT CCTGCACTGT GTGTCGTCAC 
GGCCTGTGTC GTTCCGTGGA GAAGGACAGC GTAGTGTGTG AGTGCCATCC GGGATGGACT 
GGTCCACTGT GTGATCAGGA AGCCCAGGAC CCCTGCCTTG GTCACAGCTG CAGCCATGGG 
ACATGCGTGG CGACTGGCAA CTCATATGTG TGCAAGTGTG CCGAGGGCTA TGAGGGACCT 
TTGTGTGACC AGAAGAATGA CTCTGCCAAT GCCTGCTCAG CCTTCAAGTG CCACCACGGG 
CAGTGCCACA TCTCAGATCG AGGGGAGCCC TATTGCCTGT GCCAGCCTGG CTTCAGTGGC 
AATCACTGTG AGCAAGAGAA TCCATGTTTG GGAGAGATAG TCCGTGAAGC CATCCGCCGC 
CAGAAAGATT ATGCCTCCTG TGCCACAGCA TCCAAGGTGC CCATCATGGT ATGCCGCGGG 
GGCTGCGGGA GCCAATGCTG CCAGCCGATT CGGAGCAAGC GGCGGAAATA CGTCTTCCAG 
TGCACTGACG GCTCCTCGTT CGTGGAAGAG GTGGAGAGAC ACTTGGAATG TGGCTGTCGT 
GAGTGTTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Down-regulation of N-deacetylase-N-sulfotransferase-1 signaling in the developing diaphragmatic vasculature of nitrofen-induced congenital diaphragmatic hernia.
Journal of pediatric surgery52(6)1035-1039(2017 Jun)
Takahashi T,Friedmacher F,Zimmer J,Puri P

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.
Cardiovascular research106(1)55-66(2015 Apr)
Mommersteeg MT,Yeh ML,Parnavelas JG,Andrews WD

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

Repulsive axon guidance molecule Slit3 is a novel angiogenic factor.
Blood114(19)4300-9(2009 Nov)
Zhang B,Dietrich UM,Geng JG,Bicknell R,Esko JD,Wang L

SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium.
Cancer research68(19)7819-27(2008 Oct)
Marlow R,Strickland P,Lee JS,Wu X,Pebenito M,Binnewies M,Le EK,Moran A,Macias H,Cardiff RD,Sukumar S,Hinck L

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Slit3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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