Hes3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hes3
Entrez Gene ID	64628
Full Name	hes family bHLH transcription factor 3
General protein information	Preferred Names hes family bHLH transcription factor 3 Names transcription factor HES-3 hairy and enhancer of split 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36
Summary	helix-loop-helix (HLH) protein; may function as repressor in neurons [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017593612.1	XP_017449101.1	transcription factor HES-3 isoform X1
XM_017593613.1	XP_017449102.1	transcription factor HES-3 isoform X1
XM_017593614.1	XP_017449103.1	transcription factor HES-3 isoform X1
NM_022687.1	NP_073178.1	transcription factor HES-3
XM_008764381.2	XP_008762603.1	transcription factor HES-3 isoform X1
XM_008764383.1	XP_008762605.1	transcription factor HES-3 isoform X1
XM_008764382.2	XP_008762604.1	transcription factor HES-3 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Hes3	NP_032263.2
Xenopus tropicalis (tropical clawed frog)	hes3	XP_004916246.1
Homo sapiens (human)	HES3	NP_001019769.1
Rattus norvegicus (Norway rat)	Hes3	NP_073178.1
Bos taurus (cattle)	HES3	XP_002694158.3
Pan troglodytes (chimpanzee)	HES3	XP_003949331.1
Canis lupus familiaris (dog)	HES3	XP_005620508.1

Gene Ontology
Bibliography

Related articles in PubMed

Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis.
Kinameri E, Inoue T, Aruga J, Imayoshi I, Kageyama R, Shimogori T, Moore AW
PloS one3(12)e3859(2008)

Secondary lymphoid organ chemokine reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
Sharma S, Stolina M, Zhu L, Lin Y, Batra R, Huang M, Strieter R, Dubinett SM
Cancer research61(17)6406-12(2001 Sep)

Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.
Hirata H, Tomita K, Bessho Y, Kageyama R
The EMBO journal20(16)4454-66(2001 Aug)

Generation of structurally and functionally distinct factors from the basic helix-loop-helix gene Hes3 by alternative first exons.
Hirata H, Ohtsuka T, Bessho Y, Kageyama R
The Journal of biological chemistry275(25)19083-9(2000 Jun)

Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split.
Sasai Y, Kageyama R, Tagawa Y, Shigemoto R, Nakanishi S
Genes & development6(12B)2620-34(1992 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hes3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hes3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06255	NM_022687.1 Latest version!	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa06255	XM_008764383.1 Latest version!	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa06255	XM_017593612.1 Latest version!	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa06255	XM_017593613.1 Latest version!	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa06255	XM_008764382.2 Latest version!	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa06255	XM_008764381.2 Latest version!	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa06255	XM_017593614.1 Latest version!	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hes3 ( NM_022687.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_073178.1 Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), mRNA.

Price & Availability↑

CloneID	ORa06255
Clone ID Related Accession (Same CDS sequence)	XM_017593612.1 , XM_017593613.1 , XM_017593614.1 , NM_022687.1 , XM_008764381.2 , XM_008764383.1 , XM_008764382.2
Accession Version	NM_022687.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Rattus norvegicus(Norway rat)
Product	transcription factor HES-3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D13418.1. ##Evidence-Data-START## Transcript exon combination :: D13418.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689595, SAMN02642602 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073178.1
CDS	277..804
Translation	MEKKRRARINLSLEQLRSLLERHYSHQIRKRKLEKADILELSVKYVRSLQNSLQGLWLVPSGVDYPSGFRGGLPGSSQRLRPGEDDSGLRCPLLLQRRAGSTTDSANPQTASVLSPCLPAIWAPGPPAGGSQSPQSPFPPLGGLLESSTGILAPPPASNCQAENPRPGFRVWRPW

Target ORF information:

RefSeq Version	NM_022687.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022687.1

ORF Insert Sequence:

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hes3 ( XM_017593612.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017449101.1 Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa06255
Clone ID Related Accession (Same CDS sequence)	XM_017593612.1 , XM_017593613.1 , XM_017593614.1 , NM_022687.1 , XM_008764381.2 , XM_008764383.1 , XM_008764382.2
Accession Version	XM_017593612.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	transcription factor HES-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017449101.1
CDS	1122..1649
Translation	MEKKRRARINLSLEQLRSLLERHYSHQIRKRKLEKADILELSVKYVRSLQNSLQGLWLVPSGVDYPSGFRGGLPGSSQRLRPGEDDSGLRCPLLLQRRAGSTTDSANPQTASVLSPCLPAIWAPGPPAGGSQSPQSPFPPLGGLLESSTGILAPPPASNCQAENPRPGFRVWRPW

Target ORF information:

RefSeq Version	XM_017593612.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017593612.1

ORF Insert Sequence:

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hes3 ( XM_017593613.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017449102.1 Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa06255
Clone ID Related Accession (Same CDS sequence)	XM_017593612.1 , XM_017593613.1 , XM_017593614.1 , NM_022687.1 , XM_008764381.2 , XM_008764383.1 , XM_008764382.2
Accession Version	XM_017593613.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	transcription factor HES-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017449102.1
CDS	334..861
Translation	MEKKRRARINLSLEQLRSLLERHYSHQIRKRKLEKADILELSVKYVRSLQNSLQGLWLVPSGVDYPSGFRGGLPGSSQRLRPGEDDSGLRCPLLLQRRAGSTTDSANPQTASVLSPCLPAIWAPGPPAGGSQSPQSPFPPLGGLLESSTGILAPPPASNCQAENPRPGFRVWRPW

Target ORF information:

RefSeq Version	XM_017593613.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017593613.1

ORF Insert Sequence:

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hes3 ( XM_017593614.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017449103.1 Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa06255
Clone ID Related Accession (Same CDS sequence)	XM_017593612.1 , XM_017593613.1 , XM_017593614.1 , NM_022687.1 , XM_008764381.2 , XM_008764383.1 , XM_008764382.2
Accession Version	XM_017593614.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	transcription factor HES-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017449103.1
CDS	1058..1585
Translation	MEKKRRARINLSLEQLRSLLERHYSHQIRKRKLEKADILELSVKYVRSLQNSLQGLWLVPSGVDYPSGFRGGLPGSSQRLRPGEDDSGLRCPLLLQRRAGSTTDSANPQTASVLSPCLPAIWAPGPPAGGSQSPQSPFPPLGGLLESSTGILAPPPASNCQAENPRPGFRVWRPW

Target ORF information:

RefSeq Version	XM_017593614.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017593614.1

ORF Insert Sequence:

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hes3 ( XM_008764381.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008762603.1 Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa06255
Clone ID Related Accession (Same CDS sequence)	XM_017593612.1 , XM_017593613.1 , XM_017593614.1 , NM_022687.1 , XM_008764381.2 , XM_008764383.1 , XM_008764382.2
Accession Version	XM_008764381.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	transcription factor HES-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008764381.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008762603.1
CDS	379..906
Translation	MEKKRRARINLSLEQLRSLLERHYSHQIRKRKLEKADILELSVKYVRSLQNSLQGLWLVPSGVDYPSGFRGGLPGSSQRLRPGEDDSGLRCPLLLQRRAGSTTDSANPQTASVLSPCLPAIWAPGPPAGGSQSPQSPFPPLGGLLESSTGILAPPPASNCQAENPRPGFRVWRPW

Target ORF information:

RefSeq Version	XM_008764381.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008764381.2

ORF Insert Sequence:

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hes3 ( XM_008764383.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008762605.1 Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X6, mRNA.

Price & Availability↑

CloneID	ORa06255
Clone ID Related Accession (Same CDS sequence)	XM_017593612.1 , XM_017593613.1 , XM_017593614.1 , NM_022687.1 , XM_008764381.2 , XM_008764383.1 , XM_008764382.2
Accession Version	XM_008764383.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	transcription factor HES-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008762605.1
CDS	252..779
Translation	MEKKRRARINLSLEQLRSLLERHYSHQIRKRKLEKADILELSVKYVRSLQNSLQGLWLVPSGVDYPSGFRGGLPGSSQRLRPGEDDSGLRCPLLLQRRAGSTTDSANPQTASVLSPCLPAIWAPGPPAGGSQSPQSPFPPLGGLLESSTGILAPPPASNCQAENPRPGFRVWRPW

Target ORF information:

RefSeq Version	XM_008764383.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008764383.1

ORF Insert Sequence:

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hes3 ( XM_008764382.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008762604.1 Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa06255
Clone ID Related Accession (Same CDS sequence)	XM_017593612.1 , XM_017593613.1 , XM_017593614.1 , NM_022687.1 , XM_008764381.2 , XM_008764383.1 , XM_008764382.2
Accession Version	XM_008764382.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	transcription factor HES-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008764382.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008762604.1
CDS	315..842
Translation	MEKKRRARINLSLEQLRSLLERHYSHQIRKRKLEKADILELSVKYVRSLQNSLQGLWLVPSGVDYPSGFRGGLPGSSQRLRPGEDDSGLRCPLLLQRRAGSTTDSANPQTASVLSPCLPAIWAPGPPAGGSQSPQSPFPPLGGLLESSTGILAPPPASNCQAENPRPGFRVWRPW

Target ORF information:

RefSeq Version	XM_008764382.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus hes family bHLH transcription factor 3 (Hes3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008764382.2

ORF Insert Sequence:

ATGGAGAAGA AGCGTCGTGC CCGCATCAAC CTGTCACTGG AGCAGCTAAG GTCTCTTCTG 
GAGAGACACT ACTCCCACCA GATACGGAAG CGAAAGCTGG AGAAGGCCGA TATCCTGGAG 
CTGAGCGTTA AGTACGTGAG AAGCCTCCAG AACTCATTGC AAGGACTTTG GCTAGTACCC 
AGTGGGGTGG ACTACCCGTC CGGATTCCGA GGCGGCTTGC CGGGCTCCAG CCAGAGGCTT 
CGGCCCGGAG AGGACGACAG CGGCCTGCGC TGCCCCCTGC TTCTCCAGCG CAGGGCAGGC 
AGCACCACGG ACAGCGCCAA CCCACAGACG GCCTCTGTTC TCAGCCCCTG CCTCCCGGCC 
ATCTGGGCCC CTGGTCCCCC TGCAGGTGGC TCCCAATCCC CGCAGTCCCC GTTCCCTCCC 
CTTGGAGGTC TCCTTGAGTC CTCCACTGGC ATTCTGGCAC CGCCACCTGC ATCAAACTGC 
CAGGCCGAGA ATCCGAGACC CGGGTTTCGC GTGTGGCGGC CCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis.
PloS one3(12)e3859(2008)
Kinameri E,Inoue T,Aruga J,Imayoshi I,Kageyama R,Shimogori T,Moore AW

Secondary lymphoid organ chemokine reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
Cancer research61(17)6406-12(2001 Sep)
Sharma S,Stolina M,Zhu L,Lin Y,Batra R,Huang M,Strieter R,Dubinett SM

Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.
The EMBO journal20(16)4454-66(2001 Aug)
Hirata H,Tomita K,Bessho Y,Kageyama R

Generation of structurally and functionally distinct factors from the basic helix-loop-helix gene Hes3 by alternative first exons.
The Journal of biological chemistry275(25)19083-9(2000 Jun)
Hirata H,Ohtsuka T,Bessho Y,Kageyama R

Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split.
Genes & development6(12B)2620-34(1992 Dec)
Sasai Y,Kageyama R,Tagawa Y,Shigemoto R,Nakanishi S