Decr2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Decr2
Entrez Gene ID	64461
Full Name	2,4-dienoyl-CoA reductase 2
Synonyms	Dcrakl,putativeperoxisomal24-dienoyl-CoAreductase
General protein information	Preferred Names 2,4-dienoyl-CoA reductase 2 Names peroxisomal 2,4-dienoyl-CoA reductase 2,4-dienoyl CoA reductase 2, peroxisomal 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal DCR-AKL pVI-AKL putative peroxisomal 2,4-dienoyl-CoA reductase putative peroxisomal 24-dienoyl-CoA reductase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q12
Summary	required for the degradation of unsaturated fatty acids [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006246024.3	XP_006246086.1	peroxisomal 2,4-dienoyl-CoA reductase isoform X1
NM_171996.3	NP_741993.1	peroxisomal 2,4-dienoyl-CoA reductase

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	LOC100858408	XP_003642207.2
Kluyveromyces lactis	KLLA0D18909g	XP_453899.1
Eremothecium gossypii	AGOS_ABL163W	NP_982784.1
Magnaporthe oryzae (rice blast fungus)	MGG_05138	XP_003712668.1
Oryza sativa (rice)	Os04g0614000	NP_001053860.1
Homo sapiens (human)	DECR2	NP_065715.1
Saccharomyces cerevisiae (baker's yeast)	SPS19	NP_014197.2
Neurospora crassa	NCU07958	XP_962091.1
Arabidopsis thaliana (thale cress)	SDRB	NP_187886.2
Pan troglodytes (chimpanzee)	DECR2	XP_003314934.1
Danio rerio (zebrafish)	decr2	NP_998486.1
Canis lupus familiaris (dog)	DECR2	XP_005622165.1
Mus musculus (house mouse)	Decr2	NP_036063.1
Rattus norvegicus (Norway rat)	Decr2	NP_741993.1
Xenopus tropicalis (tropical clawed frog)	decr2	XP_004918073.1

Gene Ontology
Bibliography

Related articles in PubMed

A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities.
Ghosh D, Berg JM
Journal of the American Chemical Society132(11)3973-9(2010 Mar)

Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease.
Kikuchi M, Hatano N, Yokota S, Shimozawa N, Imanaka T, Taniguchi H
The Journal of biological chemistry279(1)421-8(2004 Jan)

Identification of a novel human peroxisomal 2,4-dienoyl-CoA reductase related protein using the M13 phage protein VI phage display technology.
Amery L, Mannaerts GP, Subramani S, Van Veldhoven PP, Fransen M
Combinatorial chemistry & high throughput screening4(7)545-52(2001 Nov)

Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase.
De Nys K, Meyhi E, Mannaerts GP, Fransen M, Van Veldhoven PP
Biochimica et biophysica acta1533(1)66-72(2001 Aug)

Molecular cloning and expression of mammalian peroxisomal trans-2-enoyl-coenzyme A reductase cDNAs.
Das AK, Uhler MD, Hajra AK
The Journal of biological chemistry275(32)24333-40(2000 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Decr2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Decr2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05967	NM_171996.3 Latest version!	Rattus norvegicus 2,4-dienoyl-CoA reductase 2 (Decr2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa05967	XM_006246024.3 Latest version!	Rattus norvegicus 2,4-dienoyl CoA reductase 2, peroxisomal (Decr2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Decr2 ( NM_171996.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_741993.1 Rattus norvegicus 2,4-dienoyl-CoA reductase 2 (Decr2), mRNA.

Price & Availability↑

CloneID	ORa05967
Clone ID Related Accession (Same CDS sequence)	XM_006246024.3 , NM_171996.3
Accession Version	NM_171996.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	peroxisomal 2,4-dienoyl-CoA reductase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC070959.1. On Aug 31, 2012 this sequence version replaced NM_171996.2. ##Evidence-Data-START## Transcript exon combination :: BC070959.1, AF044574.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906356, SAMN02642782 [ECO:0000348] ##Evidence-Data-END##

ATGACCCAGC AGCCGCCTGA CGTTGAGGAG GATGACTGTC TTTCTGAATA CCACCACCTC 
TTCTGCCCGG ACCTTCTCCA GGACAAAGTG GCTTTTATCA CTGGTGGTGG TTCTGGGATT 
GGCTTCCGGA TCGCCGAGAT TTTCATGAGG CATGGCTGCC ACACTGTCAT CGTCAGCAGG 
AGTCTGCCGA GAGTGTCCGA GGCTGCTAAG AAGTTGGTTG CTGCCACTGG AAAGCGGTGT 
CTCCCTCTGT CTATGGATGT CCGAGTTCCC CCAGCTGTCA TGGCTGCTGT GGACCAAGCG 
CTGAAAGAAT TTGGCAAAAT CGACATCCTC ATTAACTGTG CTGCAGGGAA CTTTTTATGC 
CCTGCCAGTG CATTGTCTTT CAATGCCTTT AAGACTGTGG TGGACATTGA CACCCTTGGC 
ACCTTCAATG TGTCTCGTGT GCTTTATGAG AAGTTCTTCC GGGACCATGG AGGAGTGATC 
GTGAACATTA CCGCCACCCT CAGTATGCGG GGGCAGGTGC TGCAGCTCCA TGCAGGCGCT 
GCCAAGGCGG CTGTGGATGC TATGACGCGA CACTTGGCTG TGGAGTGGGG TCCCCAGAAT 
ATCCGTGTCA ACAGCCTGGC TCCTGGTGCC ATCAGCGGCA CTGAGGGTCT GCGGAGATTA 
GGAGGCCCCA AGGCCAGTTC GAAATTTAAG TATCTTTCAA GTCCTATTCC AAGACTCGGA 
ACCAAGACAG AAATCGCCCA CAGCGTGCTG TACCTAGCCA GCCCTCTGGC TTCCTATGTC 
TCAGGGATTG TGTTGGTGGT TGATGGTGGT AGCTGGATGA CGCTCCCAAA TGACATTGGG 
CGACTGCTAG AGTTTGAATC CTCCTCTGCT AAGCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_741993.1
CDS	91..969
Translation	MTQQPPDVEEDDCLSEYHHLFCPDLLQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVSRSLPRVSEAAKKLVAATGKRCLPLSMDVRVPPAVMAAVDQALKEFGKIDILINCAAGNFLCPASALSFNAFKTVVDIDTLGTFNVSRVLYEKFFRDHGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHLAVEWGPQNIRVNSLAPGAISGTEGLRRLGGPKASSKFKYLSSPIPRLGTKTEIAHSVLYLASPLASYVSGIVLVVDGGSWMTLPNDIGRLLEFESSSAKL

Target ORF information:

RefSeq Version	NM_171996.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 2,4-dienoyl-CoA reductase 2 (Decr2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_171996.3

ORF Insert Sequence:

ATGACCCAGC AGCCGCCTGA CGTTGAGGAG GATGACTGTC TTTCTGAATA CCACCACCTC 
TTCTGCCCGG ACCTTCTCCA GGACAAAGTG GCTTTTATCA CTGGTGGTGG TTCTGGGATT 
GGCTTCCGGA TCGCCGAGAT TTTCATGAGG CATGGCTGCC ACACTGTCAT CGTCAGCAGG 
AGTCTGCCGA GAGTGTCCGA GGCTGCTAAG AAGTTGGTTG CTGCCACTGG AAAGCGGTGT 
CTCCCTCTGT CTATGGATGT CCGAGTTCCC CCAGCTGTCA TGGCTGCTGT GGACCAAGCG 
CTGAAAGAAT TTGGCAAAAT CGACATCCTC ATTAACTGTG CTGCAGGGAA CTTTTTATGC 
CCTGCCAGTG CATTGTCTTT CAATGCCTTT AAGACTGTGG TGGACATTGA CACCCTTGGC 
ACCTTCAATG TGTCTCGTGT GCTTTATGAG AAGTTCTTCC GGGACCATGG AGGAGTGATC 
GTGAACATTA CCGCCACCCT CAGTATGCGG GGGCAGGTGC TGCAGCTCCA TGCAGGCGCT 
GCCAAGGCGG CTGTGGATGC TATGACGCGA CACTTGGCTG TGGAGTGGGG TCCCCAGAAT 
ATCCGTGTCA ACAGCCTGGC TCCTGGTGCC ATCAGCGGCA CTGAGGGTCT GCGGAGATTA 
GGAGGCCCCA AGGCCAGTTC GAAATTTAAG TATCTTTCAA GTCCTATTCC AAGACTCGGA 
ACCAAGACAG AAATCGCCCA CAGCGTGCTG TACCTAGCCA GCCCTCTGGC TTCCTATGTC 
TCAGGGATTG TGTTGGTGGT TGATGGTGGT AGCTGGATGA CGCTCCCAAA TGACATTGGG 
CGACTGCTAG AGTTTGAATC CTCCTCTGCT AAGCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Decr2 ( XM_006246024.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006246086.1 Rattus norvegicus 2,4-dienoyl CoA reductase 2, peroxisomal (Decr2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa05967
Clone ID Related Accession (Same CDS sequence)	XM_006246024.3 , NM_171996.3
Accession Version	XM_006246024.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	peroxisomal 2,4-dienoyl-CoA reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006246024.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCAGC AGCCGCCTGA CGTTGAGGAG GATGACTGTC TTTCTGAATA CCACCACCTC 
TTCTGCCCGG ACCTTCTCCA GGACAAAGTG GCTTTTATCA CTGGTGGTGG TTCTGGGATT 
GGCTTCCGGA TCGCCGAGAT TTTCATGAGG CATGGCTGCC ACACTGTCAT CGTCAGCAGG 
AGTCTGCCGA GAGTGTCCGA GGCTGCTAAG AAGTTGGTTG CTGCCACTGG AAAGCGGTGT 
CTCCCTCTGT CTATGGATGT CCGAGTTCCC CCAGCTGTCA TGGCTGCTGT GGACCAAGCG 
CTGAAAGAAT TTGGCAAAAT CGACATCCTC ATTAACTGTG CTGCAGGGAA CTTTTTATGC 
CCTGCCAGTG CATTGTCTTT CAATGCCTTT AAGACTGTGG TGGACATTGA CACCCTTGGC 
ACCTTCAATG TGTCTCGTGT GCTTTATGAG AAGTTCTTCC GGGACCATGG AGGAGTGATC 
GTGAACATTA CCGCCACCCT CAGTATGCGG GGGCAGGTGC TGCAGCTCCA TGCAGGCGCT 
GCCAAGGCGG CTGTGGATGC TATGACGCGA CACTTGGCTG TGGAGTGGGG TCCCCAGAAT 
ATCCGTGTCA ACAGCCTGGC TCCTGGTGCC ATCAGCGGCA CTGAGGGTCT GCGGAGATTA 
GGAGGCCCCA AGGCCAGTTC GAAATTTAAG TATCTTTCAA GTCCTATTCC AAGACTCGGA 
ACCAAGACAG AAATCGCCCA CAGCGTGCTG TACCTAGCCA GCCCTCTGGC TTCCTATGTC 
TCAGGGATTG TGTTGGTGGT TGATGGTGGT AGCTGGATGA CGCTCCCAAA TGACATTGGG 
CGACTGCTAG AGTTTGAATC CTCCTCTGCT AAGCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006246086.1
CDS	303..1181
Translation	MTQQPPDVEEDDCLSEYHHLFCPDLLQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVSRSLPRVSEAAKKLVAATGKRCLPLSMDVRVPPAVMAAVDQALKEFGKIDILINCAAGNFLCPASALSFNAFKTVVDIDTLGTFNVSRVLYEKFFRDHGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHLAVEWGPQNIRVNSLAPGAISGTEGLRRLGGPKASSKFKYLSSPIPRLGTKTEIAHSVLYLASPLASYVSGIVLVVDGGSWMTLPNDIGRLLEFESSSAKL

Target ORF information:

RefSeq Version	XM_006246024.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 2,4-dienoyl CoA reductase 2, peroxisomal (Decr2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006246024.3

ORF Insert Sequence:

ATGACCCAGC AGCCGCCTGA CGTTGAGGAG GATGACTGTC TTTCTGAATA CCACCACCTC 
TTCTGCCCGG ACCTTCTCCA GGACAAAGTG GCTTTTATCA CTGGTGGTGG TTCTGGGATT 
GGCTTCCGGA TCGCCGAGAT TTTCATGAGG CATGGCTGCC ACACTGTCAT CGTCAGCAGG 
AGTCTGCCGA GAGTGTCCGA GGCTGCTAAG AAGTTGGTTG CTGCCACTGG AAAGCGGTGT 
CTCCCTCTGT CTATGGATGT CCGAGTTCCC CCAGCTGTCA TGGCTGCTGT GGACCAAGCG 
CTGAAAGAAT TTGGCAAAAT CGACATCCTC ATTAACTGTG CTGCAGGGAA CTTTTTATGC 
CCTGCCAGTG CATTGTCTTT CAATGCCTTT AAGACTGTGG TGGACATTGA CACCCTTGGC 
ACCTTCAATG TGTCTCGTGT GCTTTATGAG AAGTTCTTCC GGGACCATGG AGGAGTGATC 
GTGAACATTA CCGCCACCCT CAGTATGCGG GGGCAGGTGC TGCAGCTCCA TGCAGGCGCT 
GCCAAGGCGG CTGTGGATGC TATGACGCGA CACTTGGCTG TGGAGTGGGG TCCCCAGAAT 
ATCCGTGTCA ACAGCCTGGC TCCTGGTGCC ATCAGCGGCA CTGAGGGTCT GCGGAGATTA 
GGAGGCCCCA AGGCCAGTTC GAAATTTAAG TATCTTTCAA GTCCTATTCC AAGACTCGGA 
ACCAAGACAG AAATCGCCCA CAGCGTGCTG TACCTAGCCA GCCCTCTGGC TTCCTATGTC 
TCAGGGATTG TGTTGGTGGT TGATGGTGGT AGCTGGATGA CGCTCCCAAA TGACATTGGG 
CGACTGCTAG AGTTTGAATC CTCCTCTGCT AAGCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities.
Journal of the American Chemical Society132(11)3973-9(2010 Mar)
Ghosh D,Berg JM

Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease.
The Journal of biological chemistry279(1)421-8(2004 Jan)
Kikuchi M,Hatano N,Yokota S,Shimozawa N,Imanaka T,Taniguchi H

Identification of a novel human peroxisomal 2,4-dienoyl-CoA reductase related protein using the M13 phage protein VI phage display technology.
Combinatorial chemistry & high throughput screening4(7)545-52(2001 Nov)
Amery L,Mannaerts GP,Subramani S,Van Veldhoven PP,Fransen M

Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase.
Biochimica et biophysica acta1533(1)66-72(2001 Aug)
De Nys K,Meyhi E,Mannaerts GP,Fransen M,Van Veldhoven PP

Molecular cloning and expression of mammalian peroxisomal trans-2-enoyl-coenzyme A reductase cDNAs.
The Journal of biological chemistry275(32)24333-40(2000 Aug)
Das AK,Uhler MD,Hajra AK