Cd200r1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cd200r1
Entrez Gene ID	64357
Full Name	CD200 receptor 1
Synonyms	Mox2r
General protein information	Preferred Names CD200 receptor 1 Names cell surface glycoprotein CD200 receptor 1 CD200 cell surface glycoprotein receptor OX102 antigen OX2 receptor antigen identified by monoclonal antibody MRC OX-2 receptor cell surface glycoprotein OX2 receptor 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q21
Summary	a receptor for membrane glycoprotein, OX2; may have a role in myeloid function [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008768743.2	XP_008766965.1	cell surface glycoprotein CD200 receptor 1 isoform X1
XM_006248347.3	XP_006248409.1	cell surface glycoprotein CD200 receptor 1 isoform X2
NM_023953.1	NP_076443.1	cell surface glycoprotein CD200 receptor 1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CD200R1	XP_001156654.1
Bos taurus (cattle)	CD200R1	XP_002684796.3
Xenopus tropicalis (tropical clawed frog)	LOC100485346	XP_002940963.1
Canis lupus familiaris (dog)	CD200R1	XP_545099.2
Mus musculus (house mouse)	Cd200r1	NP_067300.1
Rattus norvegicus (Norway rat)	Cd200r1	NP_076443.1
Gallus gallus (chicken)	CD200R1	NP_001072952.1
Homo sapiens (human)	CD200R1	NP_620161.1
	CD200R1	XP_001105494.1
Xenopus tropicalis (tropical clawed frog)	LOC101731740	XP_004912495.1
Xenopus tropicalis (tropical clawed frog)	LOC101731855	XP_004912497.1
Bos taurus (cattle)	CD200R1L	NP_001092844.1
Gallus gallus (chicken)	CD200R1L	NP_001025953.2
Xenopus tropicalis (tropical clawed frog)	LOC100127716	NP_001106521.1
Xenopus tropicalis (tropical clawed frog)	LOC101731799	XP_004912496.1

Gene Ontology
Bibliography

Related articles in PubMed

Lung CD200 Receptor Activation Abrogates Airway Hyperresponsiveness in Experimental Asthma.
Lauzon-Joset JF, Langlois A, Lai LJ, Santerre K, Lee-Gosselin A, Boss? Y, Marsolais D, Bissonnette EY
American journal of respiratory cell and molecular biology53(2)276-84(2015 Aug)

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li SS, Teasdale RD, Collins BM
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)

CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease.
Zhang S, Wang XJ, Tian LP, Pan J, Lu GQ, Zhang YJ, Ding JQ, Chen SD
Journal of neuroinflammation8154(2011 Nov)

Distribution of the immune inhibitory molecules CD200 and CD200R in the normal central nervous system and multiple sclerosis lesions suggests neuron-glia and glia-glia interactions.
Koning N, Swaab DF, Hoek RM, Huitinga I
Journal of neuropathology and experimental neurology68(2)159-67(2009 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In the context of an acute response, CD200 potently interferes with local immunopathogenic mechanisms, most likely through the activation of CD200R.
Title: Lung CD200 Receptor Activation Abrogates Airway Hyperresponsiveness in Experimental Asthma.

Results suggest that dysfunction of CD200-CD200R signalling may be involved in the aetiopathogenesis of Parkinson disease.
Title: CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease.

We show that the rat cytomegalovirus CD200 orthologue (e127) binds CD200R on rat peritoneal macrophages.
Title: Cytomegalovirus e127 protein interacts with the inhibitory CD200 receptor.

The CD200-CD200R pathway seems of critical relevance for macrophage-mediated damage in autoimmune inflammation of the CNS.
Title: CNS inflammation and neuronal degeneration is aggravated by impaired CD200-CD200R-mediated macrophage silencing.

The following Cd200r1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd200r1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06628	NM_023953.1 Latest version!	Rattus norvegicus CD200 receptor 1 (Cd200r1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa34281	XM_008768743.2 Latest version!	Rattus norvegicus CD200 receptor 1 (Cd200r1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa34282	XM_006248347.3 Latest version!	Rattus norvegicus CD200 receptor 1 (Cd200r1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd200r1 ( NM_023953.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_076443.1 Rattus norvegicus CD200 receptor 1 (Cd200r1), mRNA.

Price & Availability↑

CloneID	ORa06628
Clone ID Related Accession (Same CDS sequence)	NM_023953.1
Accession Version	NM_023953.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	cell surface glycoprotein CD200 receptor 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF231392.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906348, SAMN01906349 [ECO:0000348] ##Evidence-Data-END##

ATGCTCTGCT TTTGGAGAAC TTCTCACGTA GCAGTACTCT TGATCTGGGG GGTCTTCGCG 
GCTGAGTCAA GTTGTCCTGA TAAGAATCAA ACAATGCAGA ACAATTCATC AACTATGACA 
GAAGTTAACA CTACAGTGTT TGTACAGATG GGTAAAAAGG CTCTGCTCTG CTGCCCTTCT 
ATTTCACTGA CAAAAGTAAT ATTAATAACA TGGACAATAA CCCTCAGAGG ACAGCCTTCC 
TGCATAATAT CCTACAAAGC AGACACAAGG GAGACCCATG AAAGCAACTG CTCGGACAGA 
AGCATCACCT GGGCCTCCAC ACCTGACCTC GCTCCTGACC TTCAGATCAG TGCAGTGGCC 
CTCCAGCATG AAGGGCGTTA CTCATGTGAT ATAGCAGTAC CTGACGGGAA TTTCCAAAAC 
ATCTATGACC TCCAAGTGCT GGTGCCCCCT GAAGTAACCC ACTTTCCAGG GGAAAATAGA 
ACTGCAGTTT GTGAGGCGAT TGCAGGCAAA CCTGCTGCGC AGATCTCTTG GACGCCAGAT 
GGGGATTGTG TCGCTAAGAA TGAATCACAC AGCAATGGCA CCGTGACTGT CCGGAGCACA 
TGCCACTGGG AGCAGAGCCA CGTGTCTGTC GTGTTCTGTG TTGTCTCTCA CTTGACAACT 
GGTAACCAGT CTCTGTCTAT AGAACTGGGT AGAGGGGGTG ACCAATTATT AGGATCATAC 
ATTCAATACA TCATCCCATC TATTATTATT TTGATCATCA TAGGATGCAT TTGTCTTTTG 
AAAATCAGTG GCTGCAGAAA ATGTAAATTG CCAAAATCGG GAGCTACTCC AGATATTGAG 
GAGGATGAAA TGCAGCCGTA TGCTAGCTAC ACAGAGAAGA GCAATCCACT CTATGATACT 
GTGACCACGA CGGAGGCACA CCCAGCGTCA CAAGGCAAAG TCAATGGCAC AGACTGTCTT 
ACTTTGTCAG CCATGGGAAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076443.1
CDS	1..984
Translation	MLCFWRTSHVAVLLIWGVFAAESSCPDKNQTMQNNSSTMTEVNTTVFVQMGKKALLCCPSISLTKVILITWTITLRGQPSCIISYKADTRETHESNCSDRSITWASTPDLAPDLQISAVALQHEGRYSCDIAVPDGNFQNIYDLQVLVPPEVTHFPGENRTAVCEAIAGKPAAQISWTPDGDCVAKNESHSNGTVTVRSTCHWEQSHVSVVFCVVSHLTTGNQSLSIELGRGGDQLLGSYIQYIIPSIIILIIIGCICLLKISGCRKCKLPKSGATPDIEEDEMQPYASYTEKSNPLYDTVTTTEAHPASQGKVNGTDCLTLSAMGI

Target ORF information:

RefSeq Version	NM_023953.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD200 receptor 1 (Cd200r1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023953.1

ORF Insert Sequence:

ATGCTCTGCT TTTGGAGAAC TTCTCACGTA GCAGTACTCT TGATCTGGGG GGTCTTCGCG 
GCTGAGTCAA GTTGTCCTGA TAAGAATCAA ACAATGCAGA ACAATTCATC AACTATGACA 
GAAGTTAACA CTACAGTGTT TGTACAGATG GGTAAAAAGG CTCTGCTCTG CTGCCCTTCT 
ATTTCACTGA CAAAAGTAAT ATTAATAACA TGGACAATAA CCCTCAGAGG ACAGCCTTCC 
TGCATAATAT CCTACAAAGC AGACACAAGG GAGACCCATG AAAGCAACTG CTCGGACAGA 
AGCATCACCT GGGCCTCCAC ACCTGACCTC GCTCCTGACC TTCAGATCAG TGCAGTGGCC 
CTCCAGCATG AAGGGCGTTA CTCATGTGAT ATAGCAGTAC CTGACGGGAA TTTCCAAAAC 
ATCTATGACC TCCAAGTGCT GGTGCCCCCT GAAGTAACCC ACTTTCCAGG GGAAAATAGA 
ACTGCAGTTT GTGAGGCGAT TGCAGGCAAA CCTGCTGCGC AGATCTCTTG GACGCCAGAT 
GGGGATTGTG TCGCTAAGAA TGAATCACAC AGCAATGGCA CCGTGACTGT CCGGAGCACA 
TGCCACTGGG AGCAGAGCCA CGTGTCTGTC GTGTTCTGTG TTGTCTCTCA CTTGACAACT 
GGTAACCAGT CTCTGTCTAT AGAACTGGGT AGAGGGGGTG ACCAATTATT AGGATCATAC 
ATTCAATACA TCATCCCATC TATTATTATT TTGATCATCA TAGGATGCAT TTGTCTTTTG 
AAAATCAGTG GCTGCAGAAA ATGTAAATTG CCAAAATCGG GAGCTACTCC AGATATTGAG 
GAGGATGAAA TGCAGCCGTA TGCTAGCTAC ACAGAGAAGA GCAATCCACT CTATGATACT 
GTGACCACGA CGGAGGCACA CCCAGCGTCA CAAGGCAAAG TCAATGGCAC AGACTGTCTT 
ACTTTGTCAG CCATGGGAAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd200r1 ( XM_008768743.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008766965.1 Rattus norvegicus CD200 receptor 1 (Cd200r1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa34281
Clone ID Related Accession (Same CDS sequence)	XM_008768743.2
Accession Version	XM_008768743.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cell surface glycoprotein CD200 receptor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768743.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCTGCT TTTGGAGAAC TTCTCACGTA GCAGTACTCT TGATCTGGGG GGTCTTCGCG 
GCTGAGTCAA GTTGTCCTGA TAAGAATCAA ACAATGCAGA ACAATTCATC AACTATGACA 
GAAGTGTTTG TACAGATGGG TAAAAAGGCT CTGCTCTGCT GCCCTTCTAT TTCACTGACA 
AAAGTAATAT TAATAACATG GACAATAACC CTCAGAGGAC AGCCTTCCTG CATAATATCC 
TACAAAGCAG ACACAAGGGA GACCCATGAA AGCAACTGCT CGGACAGAAG CATCACCTGG 
GCCTCCACAC CTGACCTCGC TCCTGACCTT CAGATCAGTG CAGTGGCCCT CCAGCATGAA 
GGGCGTTACT CATGTGATAT AGCAGTACCT GACGGGAATT TCCAAAACAT CTATGACCTC 
CAAGTGCTGG TGCCCCCTGA AGTAACCCAC TTTCCAGGGG AAAATAGAAC TGCAGTTTGT 
GAGGCGATTG CAGGCAAACC TGCTGCGCAG ATCTCTTGGA CGCCAGATGG GGATTGTGTC 
GCTAAGAATG AATCACACAG CAATGGCACC GTGACTGTCC GGAGCACATG CCACTGGGAG 
CAGAGCCACG TGTCTGTCGT GTTCTGTGTT GTCTCTCACT TGACAACTGG TAACCAGTCT 
CTGTCTATAG AACTGGGTAG AGGGGGTGAC CAATTATTAG GATCATACAT TCAATACATC 
ATCCCATCTA TTATTATTTT GATCATCATA GGATGCATTT GTCTTTTGAA AATCAGTGGC 
TGCAGAAAAT GTAAATTGCC AAAATCGGGA GCTACTCCAG ATATTGAGGA GGATGAAATG 
CAGCCGTATG CTAGCTACAC AGAGAAGAGC AATCCACTCT ATGATACTGT GACCACGACG 
GAGGCACACC CAGCGTCACA AGGCAAAGTC AATGGCACAG ACTGTCTTAC TTTGTCAGCC 
ATGGGAATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008766965.1
CDS	316..1287
Translation	MLCFWRTSHVAVLLIWGVFAAESSCPDKNQTMQNNSSTMTEVFVQMGKKALLCCPSISLTKVILITWTITLRGQPSCIISYKADTRETHESNCSDRSITWASTPDLAPDLQISAVALQHEGRYSCDIAVPDGNFQNIYDLQVLVPPEVTHFPGENRTAVCEAIAGKPAAQISWTPDGDCVAKNESHSNGTVTVRSTCHWEQSHVSVVFCVVSHLTTGNQSLSIELGRGGDQLLGSYIQYIIPSIIILIIIGCICLLKISGCRKCKLPKSGATPDIEEDEMQPYASYTEKSNPLYDTVTTTEAHPASQGKVNGTDCLTLSAMGI

Target ORF information:

RefSeq Version	XM_008768743.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD200 receptor 1 (Cd200r1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008768743.2

ORF Insert Sequence:

ATGCTCTGCT TTTGGAGAAC TTCTCACGTA GCAGTACTCT TGATCTGGGG GGTCTTCGCG 
GCTGAGTCAA GTTGTCCTGA TAAGAATCAA ACAATGCAGA ACAATTCATC AACTATGACA 
GAAGTGTTTG TACAGATGGG TAAAAAGGCT CTGCTCTGCT GCCCTTCTAT TTCACTGACA 
AAAGTAATAT TAATAACATG GACAATAACC CTCAGAGGAC AGCCTTCCTG CATAATATCC 
TACAAAGCAG ACACAAGGGA GACCCATGAA AGCAACTGCT CGGACAGAAG CATCACCTGG 
GCCTCCACAC CTGACCTCGC TCCTGACCTT CAGATCAGTG CAGTGGCCCT CCAGCATGAA 
GGGCGTTACT CATGTGATAT AGCAGTACCT GACGGGAATT TCCAAAACAT CTATGACCTC 
CAAGTGCTGG TGCCCCCTGA AGTAACCCAC TTTCCAGGGG AAAATAGAAC TGCAGTTTGT 
GAGGCGATTG CAGGCAAACC TGCTGCGCAG ATCTCTTGGA CGCCAGATGG GGATTGTGTC 
GCTAAGAATG AATCACACAG CAATGGCACC GTGACTGTCC GGAGCACATG CCACTGGGAG 
CAGAGCCACG TGTCTGTCGT GTTCTGTGTT GTCTCTCACT TGACAACTGG TAACCAGTCT 
CTGTCTATAG AACTGGGTAG AGGGGGTGAC CAATTATTAG GATCATACAT TCAATACATC 
ATCCCATCTA TTATTATTTT GATCATCATA GGATGCATTT GTCTTTTGAA AATCAGTGGC 
TGCAGAAAAT GTAAATTGCC AAAATCGGGA GCTACTCCAG ATATTGAGGA GGATGAAATG 
CAGCCGTATG CTAGCTACAC AGAGAAGAGC AATCCACTCT ATGATACTGT GACCACGACG 
GAGGCACACC CAGCGTCACA AGGCAAAGTC AATGGCACAG ACTGTCTTAC TTTGTCAGCC 
ATGGGAATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd200r1 ( XM_006248347.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248409.1 Rattus norvegicus CD200 receptor 1 (Cd200r1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa34282
Clone ID Related Accession (Same CDS sequence)	XM_006248347.3
Accession Version	XM_006248347.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cell surface glycoprotein CD200 receptor 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248347.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCTGCT TTTGGAGAAC TTCTCACGTA GCAGTACTCT TGATCTGGGG GGTCTTCGCG 
GCTGAGTCAA GTTGTCCTGA TAAGAATCAA ACAATGCAGA ACAATTCATC AACTATGACA 
GAAGTTAACA CTACAGTGTT TGTACAGATG GGTAAAAAGG CTCTGCTCTG CTGCCCTTCT 
ATTTCACTGA CAAAAGTAAT ATTAATAACA TGGACAATAA CCCTCAGAGG ACAGCCTTCC 
TGCATAATAT CCTACAAAGC AGACACAAGG GAGACCCATG AAAGCAACTG CTCGGACAGA 
AGCATCACCT GGGCCTCCAC ACCTGACCTC GCTCCTGACC TTCAGATCAG TGCAGTGGCC 
CTCCAGCATG AAGGGCGTTA CTCATGTGAT ATAGCAGTAC CTGACGGGAA TTTCCAAAAC 
ATCTATGACC TCCAAGTGCT GGTGCCCCCT GAAGTAACCC ACTTTCCAGG GGAAAATAGA 
ACTGCAGTTT GTGAGGCGAT TGCAGGCAAA CCTGCTGCGC AGATCTCTTG GACGCCAGAT 
GGGGATTGTG TCGCTAAGAA TGAATCACAC AGCAATGGCA CCGTGACTGT CCGGAGCACA 
TGCCACTGGG AGCAGAGCCA CGTGTCTGTC GTGTTCTGTG TTGTCTCTCA CTTGACAACT 
GGTAACCAGT CTCTGTCTAT AGAACTGGGT AGAGGGGGTG ACCAATTATT AGGATCATAC 
ATTCAATACA TCATCCCATC TATTATTATT TTGATCATCA TAGGATGCAT TTGTCTTTTG 
AAAATCAGTG GCTGCAGGAT GAAATGCAGC CGTATGCTAG CTACACAGAG AAGAGCAATC 
CACTCTATGA TACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248409.1
CDS	318..1175
Translation	MLCFWRTSHVAVLLIWGVFAAESSCPDKNQTMQNNSSTMTEVNTTVFVQMGKKALLCCPSISLTKVILITWTITLRGQPSCIISYKADTRETHESNCSDRSITWASTPDLAPDLQISAVALQHEGRYSCDIAVPDGNFQNIYDLQVLVPPEVTHFPGENRTAVCEAIAGKPAAQISWTPDGDCVAKNESHSNGTVTVRSTCHWEQSHVSVVFCVVSHLTTGNQSLSIELGRGGDQLLGSYIQYIIPSIIILIIIGCICLLKISGCRMKCSRMLATQRRAIHSMIL

Target ORF information:

RefSeq Version	XM_006248347.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD200 receptor 1 (Cd200r1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248347.3

ORF Insert Sequence:

ATGCTCTGCT TTTGGAGAAC TTCTCACGTA GCAGTACTCT TGATCTGGGG GGTCTTCGCG 
GCTGAGTCAA GTTGTCCTGA TAAGAATCAA ACAATGCAGA ACAATTCATC AACTATGACA 
GAAGTTAACA CTACAGTGTT TGTACAGATG GGTAAAAAGG CTCTGCTCTG CTGCCCTTCT 
ATTTCACTGA CAAAAGTAAT ATTAATAACA TGGACAATAA CCCTCAGAGG ACAGCCTTCC 
TGCATAATAT CCTACAAAGC AGACACAAGG GAGACCCATG AAAGCAACTG CTCGGACAGA 
AGCATCACCT GGGCCTCCAC ACCTGACCTC GCTCCTGACC TTCAGATCAG TGCAGTGGCC 
CTCCAGCATG AAGGGCGTTA CTCATGTGAT ATAGCAGTAC CTGACGGGAA TTTCCAAAAC 
ATCTATGACC TCCAAGTGCT GGTGCCCCCT GAAGTAACCC ACTTTCCAGG GGAAAATAGA 
ACTGCAGTTT GTGAGGCGAT TGCAGGCAAA CCTGCTGCGC AGATCTCTTG GACGCCAGAT 
GGGGATTGTG TCGCTAAGAA TGAATCACAC AGCAATGGCA CCGTGACTGT CCGGAGCACA 
TGCCACTGGG AGCAGAGCCA CGTGTCTGTC GTGTTCTGTG TTGTCTCTCA CTTGACAACT 
GGTAACCAGT CTCTGTCTAT AGAACTGGGT AGAGGGGGTG ACCAATTATT AGGATCATAC 
ATTCAATACA TCATCCCATC TATTATTATT TTGATCATCA TAGGATGCAT TTGTCTTTTG 
AAAATCAGTG GCTGCAGGAT GAAATGCAGC CGTATGCTAG CTACACAGAG AAGAGCAATC 
CACTCTATGA TACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lung CD200 Receptor Activation Abrogates Airway Hyperresponsiveness in Experimental Asthma.
American journal of respiratory cell and molecular biology53(2)276-84(2015 Aug)
Lauzon-Joset JF,Langlois A,Lai LJ,Santerre K,Lee-Gosselin A,Boss? Y,Marsolais D,Bissonnette EY

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)
Ghai R,Bugarcic A,Liu H,Norwood SJ,Skeldal S,Coulson EJ,Li SS,Teasdale RD,Collins BM

CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease.
Journal of neuroinflammation8154(2011 Nov)
Zhang S,Wang XJ,Tian LP,Pan J,Lu GQ,Zhang YJ,Ding JQ,Chen SD

Distribution of the immune inhibitory molecules CD200 and CD200R in the normal central nervous system and multiple sclerosis lesions suggests neuron-glia and glia-glia interactions.
Journal of neuropathology and experimental neurology68(2)159-67(2009 Feb)
Koning N,Swaab DF,Hoek RM,Huitinga I