Exoc5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Exoc5
Entrez Gene ID	60627
Full Name	exocyst complex component 5
Synonyms	Sec10l1
General protein information	Preferred Names exocyst complex component 5 Names exocyst complex component 5 71 kDa component of rsec6/8 secretory complex SEC10-like 1 exocyst complex component Sec10 p71 component of rsec6/8 secretory complex
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p14
Summary	may play a role in exocytosis and neurotransmitter release [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022204.3	NP_071540.1	exocyst complex component 5

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004147	XP_313031.3
Eremothecium gossypii	AGOS_AGL130C	NP_986537.2
Canis lupus familiaris (dog)	EXOC5	XP_547832.2
Danio rerio (zebrafish)	exoc5	NP_001107268.1
Oryza sativa (rice)	Os12g0238100	NP_001066469.1
Homo sapiens (human)	EXOC5	NP_006535.1
Pan troglodytes (chimpanzee)	EXOC5	XP_003314397.1
	EXOC5	XP_001090127.1
Bos taurus (cattle)	EXOC5	NP_001179640.1
Mus musculus (house mouse)	Exoc5	NP_997097.1
Rattus norvegicus (Norway rat)	Exoc5	NP_071540.1
Caenorhabditis elegans (roundworm)	sec-10	NP_501283.1
Schizosaccharomyces pombe (fission yeast)	sec10	NP_593654.1
Magnaporthe oryzae (rice blast fungus)	MGG_04559	XP_003710921.1
Xenopus tropicalis (tropical clawed frog)	exoc5	NP_001017342.1
Gallus gallus (chicken)	EXOC5	NP_001012607.1
Drosophila melanogaster (fruit fly)	sec10	NP_651218.1
Saccharomyces cerevisiae (baker's yeast)	SEC10	NP_013267.1
Kluyveromyces lactis	KLLA0D18260g	XP_453869.1
Arabidopsis thaliana (thale cress)	SEC10	NP_568270.3
Neurospora crassa	NCU09313	XP_963955.1

Gene Ontology
Bibliography

Related articles in PubMed

Arl13b and the exocyst interact synergistically in ciliogenesis.
Seixas C, Choi SY, Polgar N, Umberger NL, East MP, Zuo X, Moreiras H, Ghossoub R, Benmerah A, Kahn RA, Fogelgren B, Caspary T, Lipschutz JH, Barral DC
Molecular biology of the cell27(2)308-20(2016 Jan)

The exocyst gene Sec10 regulates renal epithelial monolayer homeostasis and apoptotic sensitivity.
Polgar N, Lee AJ, Lui VH, Napoli JA, Fogelgren B
American journal of physiology. Cell physiology309(3)C190-201(2015 Aug)

Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions.
Fogelgren B, Polgar N, Lui VH, Lee AJ, Tamashiro KK, Napoli JA, Walton CB, Zuo X, Lipschutz JH
PloS one10(6)e0129346(2015)

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.
Simicek M, Lievens S, Laga M, Guzenko D, Aushev VN, Kalev P, Baietti MF, Strelkov SV, Gevaert K, Tavernier J, Sablina AA
Nature cell biology15(10)1220-30(2013 Oct)

Involvement of Exoc3l, a protein structurally related to the exocyst subunit Sec6, in insulin secretion.
Saito T, Shibasaki T, Seino S
Biomedical research (Tokyo, Japan)29(2)85-91(2008 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Exoc5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Exoc5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05425	NM_022204.3 Latest version!	Rattus norvegicus exocyst complex component 5 (Exoc5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Exoc5 ( NM_022204.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071540.1 Rattus norvegicus exocyst complex component 5 (Exoc5), mRNA.

Price & Availability↑

CloneID	ORa05425
Clone ID Related Accession (Same CDS sequence)	NM_022204.3
Accession Version	NM_022204.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	exocyst complex component 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC128739.1. On Aug 31, 2012 this sequence version replaced NM_022204.2. ##Evidence-Data-START## Transcript exon combination :: BC128739.1, U79417.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906354 [ECO:0000348] ##Evidence-Data-END##

ATGGCCACGA CGGCCGAGCT CTTCGAGGAG CCTTTTGTGG CCGATGAATA CATTGAACGT 
CTCGTGTGGA GAACCCCGGG AGGTGGTTCT AGGGGTGGAC CTGAAGCTTT TGATCCTAAA 
AGGTTATTAG AAGAATTTGT GAATCATATT CAAGAACTAC AGATAATGGA TGAAAGGATT 
CAAAGGAAAG TAGAGAAGTT AGAACAGCAG TGTCAGAAGG AGGCAAAGGA GTTTGCTAAG 
AAGGTACAAG AGCTGCAGAA AAGCAACCAG GTTGCTTTCC AACATTTCCA AGAACTAGAT 
GAACACATTA GCTATGTAGC TACCAAAGTG TGTCACCTTG GAGACCAGTT GGAAGGGGTA 
AACACACCTA GACAGCGTGC AGTGGAGGCG CAGAAATTGA TGAAATACTT TAATGAGTTT 
CTAGATGGAG AATTGAAATC TGATGTTTTT ACAAATCCTG AAAAGATCAA GGAAGCAGCA 
GACGTCATTC AGAAACTGCA TCTGATCGCC CAGGAGTTAC CTTTCGATAG GTTTTCAGAA 
GTAAAATCCA AAATTGCAAG TAAATACCAC GACTTAGAAT GCCAGCTGAT TCAGGAGTTT 
ACCAGTGCAC AACGAAGAGG TGAGGTCTCC CGGATGAGGG AGGTGGCAGC TGTCCTGCTT 
CATTTTAAGG GTTATTCCCA CTGTATTGAT GTTTATATAA AGCAGTGCCA GGAGGGTGCT 
TACTTGAGAA ATGATATATT CGAAGACGCA GCAATTCTCT GTCAGCGAGT GAACAAGCAA 
GTTGGAGATA TCTTTAGTAA TCCAGAAGCA GTACTGGCTA AGCTTATTCA GAATGTGTTT 
GAAGTCAAAC TACAGAGTTT TGTGAAAGAT CAGTTAGAAG AATGTAGGAA ATCGGATGCT 
GAGCAGTATC TTAAAAGTCT GTATGATCTG TACACAAGAA CCACCAGTCT TTCCAGCAAA 
TTGATGGAGT TTAACTTAGG TACTGATAAA CAGACTTTCT TGTCTAAGCT TATCAAATCC 
ATTTTCGTTT CCTATCTGGA GAACTATATT GAAGTGGAGA TTGGATATTT GAAAAGCAGA 
AGTGCTATGA TCCTACAGCG CTATTATGAT TCAAAAAACC ACCAAAAGAG ATCCATTGGC 
ACAGGAGGTA TTCAAGATTT GAAAGAAAGG ATTAGACAAC GTACCAACTT ACCACTGGGG 
CCAAGTATTG ACACACATGG GGAGACTTTC CTATCTCAAG AAGTGGTAGT TAATCTTTTA 
CAAGAAACCA AACAAGCCTT TGAAAGATGT CATAGGCTTT CTGATCCTTC TGATTTACCA 
AGGAATGCCT TTAGAATTTT TACCATTCTT GTGGAATTTT TATGTATTGA GCATATTGAT 
TATGCTTTAG AAACGGGGCT TGCTGGAATT CCATCATCAG ATTCTAGGAA CGCAAATCTC 
TATTTTTTGG ATGTTGTACA ACAGGCCAAT ACTATTTTTC ATCTTTTTGA CAAACAGTTT 
AATGATCACC TAATGCCACT AATAAGCTCT TCTCCTAAGT TGTCTGAATG CCTCCAGAAG 
AAGAAGGAGA TAATTGAGCA GATGGAGATG AAGTTGGACA CTGGCATCGA TAGGACGTTA 
AATTGTATGA TTGGACAGAT GAAGCACATC TTGGCTGCAG AACAAAAGAA AACAGATTTT 
AAGCCAGAAG ATGAAAACAA TGTTTTGATT CAGTATACTA ATGCATGTGT AAAGGTTTGT 
GCTTATGTAA GAAAACAAGT TGAGAAGATT AAGAATTCCA TGGATGGGAA GAATGTGGAC 
ACGGTTCTGA TGGAGCTCGG AGTACGTTTC CACCGGCTTA CTTATGAGCA TCTTCAACAA 
TATTCCTACA GTTGTATGGG CGGCATGCTT GCAATTTGCG ACGTTGCTGA ATATAGAAAA 
TGTGCCAAAG ACTTCAAGAT TCCAATGGTA TTACATCTTT TTGATACTCT GCATGCACTT 
TGCAATCTCC TAGTCGTTGC TCCAGATAAT TTAAAGCAAG TCTGCTCAGG AGAACAACTG 
GCCAATCTGG ACAAGAACAT ACTCCACTCC TTCGTCCAGC TTCGAGCTGA CTATAGATCC 
GCCCGCCTGG CTCGGCACTT CAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071540.1
CDS	229..2355
Translation	MATTAELFEEPFVADEYIERLVWRTPGGGSRGGPEAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNPEKIKEAADVIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEVSRMREVAAVLLHFKGYSHCIDVYIKQCQEGAYLRNDIFEDAAILCQRVNKQVGDIFSNPEAVLAKLIQNVFEVKLQSFVKDQLEECRKSDAEQYLKSLYDLYTRTTSLSSKLMEFNLGTDKQTFLSKLIKSIFVSYLENYIEVEIGYLKSRSAMILQRYYDSKNHQKRSIGTGGIQDLKERIRQRTNLPLGPSIDTHGETFLSQEVVVNLLQETKQAFERCHRLSDPSDLPRNAFRIFTILVEFLCIEHIDYALETGLAGIPSSDSRNANLYFLDVVQQANTIFHLFDKQFNDHLMPLISSSPKLSECLQKKKEIIEQMEMKLDTGIDRTLNCMIGQMKHILAAEQKKTDFKPEDENNVLIQYTNACVKVCAYVRKQVEKIKNSMDGKNVDTVLMELGVRFHRLTYEHLQQYSYSCMGGMLAICDVAEYRKCAKDFKIPMVLHLFDTLHALCNLLVVAPDNLKQVCSGEQLANLDKNILHSFVQLRADYRSARLARHFS

Target ORF information:

RefSeq Version	NM_022204.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus exocyst complex component 5 (Exoc5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022204.3

ORF Insert Sequence:

ATGGCCACGA CGGCCGAGCT CTTCGAGGAG CCTTTTGTGG CCGATGAATA CATTGAACGT 
CTCGTGTGGA GAACCCCGGG AGGTGGTTCT AGGGGTGGAC CTGAAGCTTT TGATCCTAAA 
AGGTTATTAG AAGAATTTGT GAATCATATT CAAGAACTAC AGATAATGGA TGAAAGGATT 
CAAAGGAAAG TAGAGAAGTT AGAACAGCAG TGTCAGAAGG AGGCAAAGGA GTTTGCTAAG 
AAGGTACAAG AGCTGCAGAA AAGCAACCAG GTTGCTTTCC AACATTTCCA AGAACTAGAT 
GAACACATTA GCTATGTAGC TACCAAAGTG TGTCACCTTG GAGACCAGTT GGAAGGGGTA 
AACACACCTA GACAGCGTGC AGTGGAGGCG CAGAAATTGA TGAAATACTT TAATGAGTTT 
CTAGATGGAG AATTGAAATC TGATGTTTTT ACAAATCCTG AAAAGATCAA GGAAGCAGCA 
GACGTCATTC AGAAACTGCA TCTGATCGCC CAGGAGTTAC CTTTCGATAG GTTTTCAGAA 
GTAAAATCCA AAATTGCAAG TAAATACCAC GACTTAGAAT GCCAGCTGAT TCAGGAGTTT 
ACCAGTGCAC AACGAAGAGG TGAGGTCTCC CGGATGAGGG AGGTGGCAGC TGTCCTGCTT 
CATTTTAAGG GTTATTCCCA CTGTATTGAT GTTTATATAA AGCAGTGCCA GGAGGGTGCT 
TACTTGAGAA ATGATATATT CGAAGACGCA GCAATTCTCT GTCAGCGAGT GAACAAGCAA 
GTTGGAGATA TCTTTAGTAA TCCAGAAGCA GTACTGGCTA AGCTTATTCA GAATGTGTTT 
GAAGTCAAAC TACAGAGTTT TGTGAAAGAT CAGTTAGAAG AATGTAGGAA ATCGGATGCT 
GAGCAGTATC TTAAAAGTCT GTATGATCTG TACACAAGAA CCACCAGTCT TTCCAGCAAA 
TTGATGGAGT TTAACTTAGG TACTGATAAA CAGACTTTCT TGTCTAAGCT TATCAAATCC 
ATTTTCGTTT CCTATCTGGA GAACTATATT GAAGTGGAGA TTGGATATTT GAAAAGCAGA 
AGTGCTATGA TCCTACAGCG CTATTATGAT TCAAAAAACC ACCAAAAGAG ATCCATTGGC 
ACAGGAGGTA TTCAAGATTT GAAAGAAAGG ATTAGACAAC GTACCAACTT ACCACTGGGG 
CCAAGTATTG ACACACATGG GGAGACTTTC CTATCTCAAG AAGTGGTAGT TAATCTTTTA 
CAAGAAACCA AACAAGCCTT TGAAAGATGT CATAGGCTTT CTGATCCTTC TGATTTACCA 
AGGAATGCCT TTAGAATTTT TACCATTCTT GTGGAATTTT TATGTATTGA GCATATTGAT 
TATGCTTTAG AAACGGGGCT TGCTGGAATT CCATCATCAG ATTCTAGGAA CGCAAATCTC 
TATTTTTTGG ATGTTGTACA ACAGGCCAAT ACTATTTTTC ATCTTTTTGA CAAACAGTTT 
AATGATCACC TAATGCCACT AATAAGCTCT TCTCCTAAGT TGTCTGAATG CCTCCAGAAG 
AAGAAGGAGA TAATTGAGCA GATGGAGATG AAGTTGGACA CTGGCATCGA TAGGACGTTA 
AATTGTATGA TTGGACAGAT GAAGCACATC TTGGCTGCAG AACAAAAGAA AACAGATTTT 
AAGCCAGAAG ATGAAAACAA TGTTTTGATT CAGTATACTA ATGCATGTGT AAAGGTTTGT 
GCTTATGTAA GAAAACAAGT TGAGAAGATT AAGAATTCCA TGGATGGGAA GAATGTGGAC 
ACGGTTCTGA TGGAGCTCGG AGTACGTTTC CACCGGCTTA CTTATGAGCA TCTTCAACAA 
TATTCCTACA GTTGTATGGG CGGCATGCTT GCAATTTGCG ACGTTGCTGA ATATAGAAAA 
TGTGCCAAAG ACTTCAAGAT TCCAATGGTA TTACATCTTT TTGATACTCT GCATGCACTT 
TGCAATCTCC TAGTCGTTGC TCCAGATAAT TTAAAGCAAG TCTGCTCAGG AGAACAACTG 
GCCAATCTGG ACAAGAACAT ACTCCACTCC TTCGTCCAGC TTCGAGCTGA CTATAGATCC 
GCCCGCCTGG CTCGGCACTT CAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Arl13b and the exocyst interact synergistically in ciliogenesis.
Molecular biology of the cell27(2)308-20(2016 Jan)
Seixas C,Choi SY,Polgar N,Umberger NL,East MP,Zuo X,Moreiras H,Ghossoub R,Benmerah A,Kahn RA,Fogelgren B,Caspary T,Lipschutz JH,Barral DC

The exocyst gene Sec10 regulates renal epithelial monolayer homeostasis and apoptotic sensitivity.
American journal of physiology. Cell physiology309(3)C190-201(2015 Aug)
Polgar N,Lee AJ,Lui VH,Napoli JA,Fogelgren B

Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions.
PloS one10(6)e0129346(2015)
Fogelgren B,Polgar N,Lui VH,Lee AJ,Tamashiro KK,Napoli JA,Walton CB,Zuo X,Lipschutz JH

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.
Nature cell biology15(10)1220-30(2013 Oct)
Simicek M,Lievens S,Laga M,Guzenko D,Aushev VN,Kalev P,Baietti MF,Strelkov SV,Gevaert K,Tavernier J,Sablina AA

Involvement of Exoc3l, a protein structurally related to the exocyst subunit Sec6, in insulin secretion.
Biomedical research (Tokyo, Japan)29(2)85-91(2008 Apr)
Saito T,Shibasaki T,Seino S