Rgs1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rgs1
Entrez Gene ID	54289
Full Name	regulator of G-protein signaling 1
General protein information	Preferred Names regulator of G-protein signaling 1 Names regulator of G-protein signaling 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q21
Summary	human homolog acts as a GTPase activator and inhibits Gq mediated Ca2+ signaling [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006249974.3	XP_006250036.1	regulator of G-protein signaling 1 isoform X1
NM_019336.1	NP_062209.1	regulator of G-protein signaling 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RGS1	NP_001185992.1
Rattus norvegicus (Norway rat)	Rgs1	NP_062209.1
Xenopus tropicalis (tropical clawed frog)	rgs1	XP_002939124.2
Danio rerio (zebrafish)	rgs13	NP_001082981.1
Pan troglodytes (chimpanzee)	RGS1	XP_514068.2
Canis lupus familiaris (dog)	RGS1	XP_545702.4
Mus musculus (house mouse)	Rgs1	NP_056626.2
Gallus gallus (chicken)	RGS1	XP_422203.3
Homo sapiens (human)	RGS1	NP_002913.3
	RGS1	XP_001112975.1
Danio rerio (zebrafish)	LOC792554	XP_001332101.5

Gene Ontology
Bibliography

Related articles in PubMed

Primary gene response to mechanical loading in healing rat Achilles tendons.
Eliasson P, Andersson T, Hammerman M, Aspenberg P
Journal of applied physiology (Bethesda, Md. : 1985)114(11)1519-26(2013 Jun)

Impact of lactobacilli on orally acquired listeriosis.
Archambaud C, Nahori MA, Soubigou G, B?cavin C, Laval L, Lechat P, Smokvina T, Langella P, Lecuit M, Cossart P
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)

Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Soundararajan M, Willard FS, Kimple AJ, Turnbull AP, Ball LJ, Schoch GA, Gileadi C, Fedorov OY, Dowler EF, Higman VA, Hutsell SQ, Sundstr?m M, Doyle DA, Siderovski DP
Proceedings of the National Academy of Sciences of the United States of America105(17)6457-62(2008 Apr)

RGS1 is expressed in monocytes and acts as a GTPase-activating protein for G-protein-coupled chemoattractant receptors.
Denecke B, Meyerdierks A, B?ttger EC
The Journal of biological chemistry274(38)26860-8(1999 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Rgs1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rgs1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04462	NM_019336.1 Latest version!	Rattus norvegicus regulator of G-protein signaling 1 (Rgs1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa35429	XM_006249974.3 Latest version!	Rattus norvegicus regulator of G-protein signaling 1 (Rgs1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rgs1 ( NM_019336.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062209.1 Rattus norvegicus regulator of G-protein signaling 1 (Rgs1), mRNA.

Price & Availability↑

CloneID	ORa04462
Clone ID Related Accession (Same CDS sequence)	NM_019336.1
Accession Version	NM_019336.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	regulator of G-protein signaling 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC098681.1. On Aug 8, 2005 this sequence version replaced XM_344150.2. ##Evidence-Data-START## Transcript exon combination :: BC098681.1, DN933095.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGGACATGA AAGCATATCT AAGATCTATG ATCCCTCATC TGGAATCTGG GATGAAATCG 
TCCAAGTCCA AAGACATACT TTCGGCTGAG GAAGTAATGC AGTGGTCTCA GTCTCTGGAA 
AAACTCCTTG CCAACCAGAT GGGTCAAAAT GTCTTTGGGA AATTCCTAAA GTCTGAATTC 
AGTGAAGAGA ACATTGAATT CTGGTTGGCT TGTGAAGACT ATAAGAAAAC AGAGACTGAT 
CTTTTGCATA ACAAAGCAGA GCATATATAC AAAGCATTTG TGCACTCAGA TGCTGTGAAA 
CAAATCAATA TTGACTTTCA TACTCGGGAA TCGACAGCCA AGAAGATCAA AACACCAACT 
CCCACATGTT TTGATGAAGC ACAAAAAGTC ATATACGCAC TTATGGAAAA GGATTCTTAT 
CCCAGGTTCC TGAAATCAAA TATTTACTTA AATCTTCTAA ATGACCTTCA GGCGAATACC 
TTAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062209.1
CDS	197..685
Translation	MDMKAYLRSMIPHLESGMKSSKSKDILSAEEVMQWSQSLEKLLANQMGQNVFGKFLKSEFSEENIEFWLACEDYKKTETDLLHNKAEHIYKAFVHSDAVKQINIDFHTRESTAKKIKTPTPTCFDEAQKVIYALMEKDSYPRFLKSNIYLNLLNDLQANTLK

Target ORF information:

RefSeq Version	NM_019336.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus regulator of G-protein signaling 1 (Rgs1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019336.1

ORF Insert Sequence:

ATGGACATGA AAGCATATCT AAGATCTATG ATCCCTCATC TGGAATCTGG GATGAAATCG 
TCCAAGTCCA AAGACATACT TTCGGCTGAG GAAGTAATGC AGTGGTCTCA GTCTCTGGAA 
AAACTCCTTG CCAACCAGAT GGGTCAAAAT GTCTTTGGGA AATTCCTAAA GTCTGAATTC 
AGTGAAGAGA ACATTGAATT CTGGTTGGCT TGTGAAGACT ATAAGAAAAC AGAGACTGAT 
CTTTTGCATA ACAAAGCAGA GCATATATAC AAAGCATTTG TGCACTCAGA TGCTGTGAAA 
CAAATCAATA TTGACTTTCA TACTCGGGAA TCGACAGCCA AGAAGATCAA AACACCAACT 
CCCACATGTT TTGATGAAGC ACAAAAAGTC ATATACGCAC TTATGGAAAA GGATTCTTAT 
CCCAGGTTCC TGAAATCAAA TATTTACTTA AATCTTCTAA ATGACCTTCA GGCGAATACC 
TTAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rgs1 ( XM_006249974.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006250036.1 Rattus norvegicus regulator of G-protein signaling 1 (Rgs1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa35429
Clone ID Related Accession (Same CDS sequence)	XM_006249974.3
Accession Version	XM_006249974.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 630bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	regulator of G-protein signaling 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249974.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAGCTG CAGCCATCTC CATGCCAAGG TTGAACAAAA TGCCAGGAAT GTTCTTCTCT 
GCTAGCCCAA AGGATTCAAA AGAACCAAGC CATTCTCTTC TAGATGACAA CAAGCAAAAA 
AAGAGGCCAA AGACTTTTGG AATGGACATG AAAGCATATC TAAGATCTAT GATCCCTCAT 
CTGGAATCTG GGATGAAATC GTCCAAGTCC AAAGACATAC TTTCGGCTGA GGAAGTAATG 
CAGTGGTCTC AGTCTCTGGA AAAACTCCTT GCCAACCAGA TGGGTCAAAA TGTCTTTGGG 
AAATTCCTAA AGTCTGAATT CAGTGAAGAG AACATTGAAT TCTGGTTGGC TTGTGAAGAC 
TATAAGAAAA CAGAGACTGA TCTTTTGCAT AACAAAGCAG AGCATATATA CAAAGCATTT 
GTGCACTCAG ATGCTGTGAA ACAAATCAAT ATTGACTTTC ATACTCGGGA ATCGACAGCC 
AAGAAGATCA AAACACCAAC TCCCACATGT TTTGATGAAG CACAAAAAGT CATATACGCA 
CTTATGGAAA AGGATTCTTA TCCCAGGTTC CTGAAATCAA ATATTTACTT AAATCTTCTA 
AATGACCTTC AGGCGAATAC CTTAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006250036.1
CDS	256..885
Translation	MRAAAISMPRLNKMPGMFFSASPKDSKEPSHSLLDDNKQKKRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDILSAEEVMQWSQSLEKLLANQMGQNVFGKFLKSEFSEENIEFWLACEDYKKTETDLLHNKAEHIYKAFVHSDAVKQINIDFHTRESTAKKIKTPTPTCFDEAQKVIYALMEKDSYPRFLKSNIYLNLLNDLQANTLK

Target ORF information:

RefSeq Version	XM_006249974.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus regulator of G-protein signaling 1 (Rgs1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249974.3

ORF Insert Sequence:

ATGAGAGCTG CAGCCATCTC CATGCCAAGG TTGAACAAAA TGCCAGGAAT GTTCTTCTCT 
GCTAGCCCAA AGGATTCAAA AGAACCAAGC CATTCTCTTC TAGATGACAA CAAGCAAAAA 
AAGAGGCCAA AGACTTTTGG AATGGACATG AAAGCATATC TAAGATCTAT GATCCCTCAT 
CTGGAATCTG GGATGAAATC GTCCAAGTCC AAAGACATAC TTTCGGCTGA GGAAGTAATG 
CAGTGGTCTC AGTCTCTGGA AAAACTCCTT GCCAACCAGA TGGGTCAAAA TGTCTTTGGG 
AAATTCCTAA AGTCTGAATT CAGTGAAGAG AACATTGAAT TCTGGTTGGC TTGTGAAGAC 
TATAAGAAAA CAGAGACTGA TCTTTTGCAT AACAAAGCAG AGCATATATA CAAAGCATTT 
GTGCACTCAG ATGCTGTGAA ACAAATCAAT ATTGACTTTC ATACTCGGGA ATCGACAGCC 
AAGAAGATCA AAACACCAAC TCCCACATGT TTTGATGAAG CACAAAAAGT CATATACGCA 
CTTATGGAAA AGGATTCTTA TCCCAGGTTC CTGAAATCAA ATATTTACTT AAATCTTCTA 
AATGACCTTC AGGCGAATAC CTTAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Primary gene response to mechanical loading in healing rat Achilles tendons.
Journal of applied physiology (Bethesda, Md. : 1985)114(11)1519-26(2013 Jun)
Eliasson P,Andersson T,Hammerman M,Aspenberg P

Impact of lactobacilli on orally acquired listeriosis.
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)
Archambaud C,Nahori MA,Soubigou G,B?cavin C,Laval L,Lechat P,Smokvina T,Langella P,Lecuit M,Cossart P

Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proceedings of the National Academy of Sciences of the United States of America105(17)6457-62(2008 Apr)
Soundararajan M,Willard FS,Kimple AJ,Turnbull AP,Ball LJ,Schoch GA,Gileadi C,Fedorov OY,Dowler EF,Higman VA,Hutsell SQ,Sundstr?m M,Doyle DA,Siderovski DP

RGS1 is expressed in monocytes and acts as a GTPase-activating protein for G-protein-coupled chemoattractant receptors.
The Journal of biological chemistry274(38)26860-8(1999 Sep)
Denecke B,Meyerdierks A,B?ttger EC