Arx cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arx
Entrez Gene ID	317268
Full Name	aristaless related homeobox
Synonyms	RGD1562672
General protein information	Preferred Names aristaless related homeobox Names homeobox protein ARX
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100174.1	NP_001093644.1	homeobox protein ARX

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ARX	NP_001108138.1
	ARX	XP_001091313.1
Rattus norvegicus (Norway rat)	Arx	NP_001093644.1
Homo sapiens (human)	ARX	NP_620689.1
Mus musculus (house mouse)	Arx	NP_031518.2

Gene Ontology
Bibliography

Related articles in PubMed

The c.429_452 duplication of the ARX gene: a unique developmental-model of limb kinetic apraxia.
Curie A, Nazir T, Brun A, Paulignan Y, Reboul A, Delange K, Cheylus A, Bertrand S, Rochefort F, Bussy G, Marignier S, Lacombe D, Chiron C, Coss?e M, Leheup B, Philippe C, Laugel V, De Saint Martin A, Sacco S, Poirier K, Bienvenu T, Souville I, Gilbert-Dussardier B, Bieth E, Kauffmann D, Briot P, de Fr?minville B, Prieur F, Till M, Rooryck-Thambo C, Mortemousque I, Bobillier-Chaumont I, Toutain A, Touraine R, Sanlaville D, Chelly J, Freeman S, Kong J, Hadjikhani N, Gollub RL, Roy A, des Portes V
Orphanet journal of rare diseases925(2014 Feb)

A regulatory path associated with X-linked intellectual disability and epilepsy links KDM5C to the polyalanine expansions in ARX.
Poeta L, Fusco F, Drongitis D, Shoubridge C, Manganelli G, Filosa S, Paciolla M, Courtney M, Collombat P, Lioi MB, Gecz J, Ursini MV, Miano MG
American journal of human genetics92(1)114-25(2013 Jan)

Arx is required for normal enteroendocrine cell development in mice and humans.
Du A, McCracken KW, Walp ER, Terry NA, Klein TJ, Han A, Wells JM, May CL
Developmental biology365(1)175-88(2012 May)

High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies.
Quill? ML, Carat S, Qu?m?ner-Redon S, Hirchaud E, Baron D, Benech C, Guihot J, Placet M, Mignen O, F?rec C, Houlgatte R, Friocourt G
PloS one6(9)e25181(2011)

Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice.
Kitamura K, Itou Y, Yanazawa M, Ohsawa M, Suzuki-Migishima R, Umeki Y, Hohjoh H, Yanagawa Y, Shinba T, Itoh M, Nakamura K, Goto Y
Human molecular genetics18(19)3708-24(2009 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Arx gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arx cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11219	NM_001100174.1 Latest version!	Rattus norvegicus aristaless related homeobox (Arx), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$335.30 $479.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arx ( NM_001100174.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001093644.1 Rattus norvegicus aristaless related homeobox (Arx), mRNA.

Price & Availability↑

CloneID	ORa11219
Clone ID Related Accession (Same CDS sequence)	NM_001100174.1
Accession Version	NM_001100174.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	homeobox protein ARX
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EF638804.1. On or before Jul 29, 2007 this sequence version replaced XM_228590.4, XM_001064618.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF638804.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689600, SAMEA2689603 [ECO:0000350] ##Evidence-Data-END##

ATGAGCAATC AGTACCAGGA AGAGGGCTGC TCTGAGAGGC CCGAGTGCAA GAGTAAATCG 
CCAACTTTGC TCTCCTCCTA CTGCATCGAC AGCATCCTGG GCCGGAGAAG CCCGTGCAAA 
ATGAGGCTTC TGGGAGCCGC GCAGAGCTTG CCTGCCCCGC TGGCCAGCCG TACTGACCAA 
GAAAAAGCCA TGCAAGGCTC CCCCAAGGGC AGCAGCGCCC CGTTCGAGGC TGAGCTGCAC 
CTGCCACCCA AGCTGCGGCG CCTGTACGGC CCGGGCGGGG GCCGCCTCCT CCAGGGCGCA 
GCAGCGGCGG CAGCGGCGGC GGCCGCGGCG GCGGCGGCGG CAGCCACGGC CACTGGCACC 
GCAGGTCCCC GTGGAGAGGT TCCTCCACCG CCACCGCCAG CAGCACGGCC AGGGGAGCGT 
CAGGACAGCG CGGGGGCCGT GGCCGCCGCC GCCGCCGCTG CCTGGGACAC GCTCAAAATT 
AGCCAGGCAC CGCAGGTGAG CATCAGCCGC AGCAAGTCGT ACCGCGAGAA CGGGGCGCCC 
TTCGTGCCAC CGCCGCCCGC CCTGGACGAG CTGGGTGGTC CGGGGGGCGT CGCGCACCCA 
GAGGAGCGCC TCAGCGCGGC CAGCGGACCC GGCAGTGCCC CGGCGGCGGG TGGTGGCACG 
GGCACCGAGG AGGACGAGGA GGAGCTGTTG GAGGATGAGG AAGATGAAGA TGAGGAAGAG 
GAGCTGCTGG AGGACGACGA GGAGGAGCTG CTGGAAGACG ATGCCCGCGC GCTACTCAAG 
GAGCCCCGGC GCTGCTCTGT GGCCACCACT GGCACGGTGG CCGCCGCCGC CGCCGCCGCC 
GCTGCCGCCG CCGCCGTGGC CACCGAGGGC GGGGAGCTGT CGCCCAAGGA AGAGCTGTTG 
CTGCACCCGG AGGACGCCGA GGGCAAGGAT GGTGAGGACA GCGTGTGCCT GTCCGCCGGC 
AGCGACTCCG AGGAGGGGCT CCTGAAGCGC AAACAGAGGC GTTACCGCAC CACGTTCACC 
AGTTACCAGC TGGAGGAACT GGAGCGGGCT TTCCAGAAGA CACACTACCC TGACGTCTTC 
ACCAGGGAGG AGCTGGCCAT GAGGCTGGAC CTGACTGAGG CCCGAGTCCA GGTGTGGTTC 
CAGAACCGCA GGGCCAAGTG GCGCAAGCGG GAGAAGGCTG GCGCGCAGAC CCACCCCCCG 
GGGCTGCCCT TTCCCGGGCC ACTCTCGGCT ACCCACCCTC TCAGCCCCTA CCTGGACGCC 
AGCCCCTTTC CCCCGCATCA CCCAGCGCTT GACTCGGCCT GGACCGCCGC CGCTGCAGCG 
GCTGCAGCTG CCTTCCCGAG CCTACCTCCG CCCCCGGGCT CTGCTAGCCT GCCGCCCAGC 
GGGGCGCCGC TGGGCCTGAG CACTTTCCTG GGAGCAGCCG TGTTCCGGCA CCCGGCCTTC 
ATCAGCCCAG CATTTGGCAG GCTCTTTTCC ACTATGGCCC CCCTGACCAG CGCGTCGACC 
GCGGCTGCGC TCCTGAGACA GCCCACACCC GCAGTGGAGG GCGCAGTGGC CTCGGGCGCG 
CTGGCCGATC CCGCCACCGC TGCGGCAGAC AGACGCGCAT CGAGCATAGC GGCGCTGAGG 
CTCAAGGCTA AGGAGCACGC CGCGCAGCTC ACGCAGCTCA ACATCCTCCC GGGCACCAGC 
ACGGGGAAGG AGGTGTGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093644.1
CDS	197..1897
Translation	MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRTDQEKAMQGSPKGSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATGTAGPRGEVPPPPPPAARPGERQDSAGAVAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVAHPEERLSAASGPGSAPAAGGGTGTEEDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCSVATTGTVAAAAAAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC

Target ORF information:

RefSeq Version	NM_001100174.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus aristaless related homeobox (Arx), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100174.1

ORF Insert Sequence:

ATGAGCAATC AGTACCAGGA AGAGGGCTGC TCTGAGAGGC CCGAGTGCAA GAGTAAATCG 
CCAACTTTGC TCTCCTCCTA CTGCATCGAC AGCATCCTGG GCCGGAGAAG CCCGTGCAAA 
ATGAGGCTTC TGGGAGCCGC GCAGAGCTTG CCTGCCCCGC TGGCCAGCCG TACTGACCAA 
GAAAAAGCCA TGCAAGGCTC CCCCAAGGGC AGCAGCGCCC CGTTCGAGGC TGAGCTGCAC 
CTGCCACCCA AGCTGCGGCG CCTGTACGGC CCGGGCGGGG GCCGCCTCCT CCAGGGCGCA 
GCAGCGGCGG CAGCGGCGGC GGCCGCGGCG GCGGCGGCGG CAGCCACGGC CACTGGCACC 
GCAGGTCCCC GTGGAGAGGT TCCTCCACCG CCACCGCCAG CAGCACGGCC AGGGGAGCGT 
CAGGACAGCG CGGGGGCCGT GGCCGCCGCC GCCGCCGCTG CCTGGGACAC GCTCAAAATT 
AGCCAGGCAC CGCAGGTGAG CATCAGCCGC AGCAAGTCGT ACCGCGAGAA CGGGGCGCCC 
TTCGTGCCAC CGCCGCCCGC CCTGGACGAG CTGGGTGGTC CGGGGGGCGT CGCGCACCCA 
GAGGAGCGCC TCAGCGCGGC CAGCGGACCC GGCAGTGCCC CGGCGGCGGG TGGTGGCACG 
GGCACCGAGG AGGACGAGGA GGAGCTGTTG GAGGATGAGG AAGATGAAGA TGAGGAAGAG 
GAGCTGCTGG AGGACGACGA GGAGGAGCTG CTGGAAGACG ATGCCCGCGC GCTACTCAAG 
GAGCCCCGGC GCTGCTCTGT GGCCACCACT GGCACGGTGG CCGCCGCCGC CGCCGCCGCC 
GCTGCCGCCG CCGCCGTGGC CACCGAGGGC GGGGAGCTGT CGCCCAAGGA AGAGCTGTTG 
CTGCACCCGG AGGACGCCGA GGGCAAGGAT GGTGAGGACA GCGTGTGCCT GTCCGCCGGC 
AGCGACTCCG AGGAGGGGCT CCTGAAGCGC AAACAGAGGC GTTACCGCAC CACGTTCACC 
AGTTACCAGC TGGAGGAACT GGAGCGGGCT TTCCAGAAGA CACACTACCC TGACGTCTTC 
ACCAGGGAGG AGCTGGCCAT GAGGCTGGAC CTGACTGAGG CCCGAGTCCA GGTGTGGTTC 
CAGAACCGCA GGGCCAAGTG GCGCAAGCGG GAGAAGGCTG GCGCGCAGAC CCACCCCCCG 
GGGCTGCCCT TTCCCGGGCC ACTCTCGGCT ACCCACCCTC TCAGCCCCTA CCTGGACGCC 
AGCCCCTTTC CCCCGCATCA CCCAGCGCTT GACTCGGCCT GGACCGCCGC CGCTGCAGCG 
GCTGCAGCTG CCTTCCCGAG CCTACCTCCG CCCCCGGGCT CTGCTAGCCT GCCGCCCAGC 
GGGGCGCCGC TGGGCCTGAG CACTTTCCTG GGAGCAGCCG TGTTCCGGCA CCCGGCCTTC 
ATCAGCCCAG CATTTGGCAG GCTCTTTTCC ACTATGGCCC CCCTGACCAG CGCGTCGACC 
GCGGCTGCGC TCCTGAGACA GCCCACACCC GCAGTGGAGG GCGCAGTGGC CTCGGGCGCG 
CTGGCCGATC CCGCCACCGC TGCGGCAGAC AGACGCGCAT CGAGCATAGC GGCGCTGAGG 
CTCAAGGCTA AGGAGCACGC CGCGCAGCTC ACGCAGCTCA ACATCCTCCC GGGCACCAGC 
ACGGGGAAGG AGGTGTGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The c.429_452 duplication of the ARX gene: a unique developmental-model of limb kinetic apraxia.
Orphanet journal of rare diseases925(2014 Feb)
Curie A,Nazir T,Brun A,Paulignan Y,Reboul A,Delange K,Cheylus A,Bertrand S,Rochefort F,Bussy G,Marignier S,Lacombe D,Chiron C,Coss?e M,Leheup B,Philippe C,Laugel V,De Saint Martin A,Sacco S,Poirier K,Bienvenu T,Souville I,Gilbert-Dussardier B,Bieth E,Kauffmann D,Briot P,de Fr?minville B,Prieur F,Till M,Rooryck-Thambo C,Mortemousque I,Bobillier-Chaumont I,Toutain A,Touraine R,Sanlaville D,Chelly J,Freeman S,Kong J,Hadjikhani N,Gollub RL,Roy A,des Portes V

A regulatory path associated with X-linked intellectual disability and epilepsy links KDM5C to the polyalanine expansions in ARX.
American journal of human genetics92(1)114-25(2013 Jan)
Poeta L,Fusco F,Drongitis D,Shoubridge C,Manganelli G,Filosa S,Paciolla M,Courtney M,Collombat P,Lioi MB,Gecz J,Ursini MV,Miano MG

Arx is required for normal enteroendocrine cell development in mice and humans.
Developmental biology365(1)175-88(2012 May)
Du A,McCracken KW,Walp ER,Terry NA,Klein TJ,Han A,Wells JM,May CL

High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies.
PloS one6(9)e25181(2011)
Quill? ML,Carat S,Qu?m?ner-Redon S,Hirchaud E,Baron D,Benech C,Guihot J,Placet M,Mignen O,F?rec C,Houlgatte R,Friocourt G

Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice.
Human molecular genetics18(19)3708-24(2009 Oct)
Kitamura K,Itou Y,Yanazawa M,Ohsawa M,Suzuki-Migishima R,Umeki Y,Hohjoh H,Yanagawa Y,Shinba T,Itoh M,Nakamura K,Goto Y

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Arx cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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