Mdm2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mdm2
Entrez Gene ID	314856
Full Name	MDM2 proto-oncogene
General protein information	Preferred Names MDM2 proto-oncogene Names E3 ubiquitin-protein ligase Mdm2 MDM2 oncogene, E3 ubiquitin protein ligase MDM2 proto-oncogene, E3 ubiquitin protein ligase Mdm2 p53 binding protein homolog double minute 2 p53 E3 ubiquitin protein ligase transformed mouse 3T3 cell double minute 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q22
Summary	mouse homolog acts to inhibit p53 growth suppression in Ras transformed cells [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008765397.1	XP_008763619.1	E3 ubiquitin-protein ligase Mdm2 isoform X1
XM_006241382.1	XP_006241444.1	E3 ubiquitin-protein ligase Mdm2 isoform X2
NM_001108099.1	NP_001101569.1	E3 ubiquitin-protein ligase Mdm2
XM_006241383.2	XP_006241445.1	E3 ubiquitin-protein ligase Mdm2 isoform X2
XM_008765396.1	XP_008763618.1	E3 ubiquitin-protein ligase Mdm2 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Mdm2	NP_001101569.1
Gallus gallus (chicken)	MDM2	NP_001186313.1
Danio rerio (zebrafish)	mdm2	NP_571439.2
Xenopus tropicalis (tropical clawed frog)	mdm2	NP_001231689.1
Mus musculus (house mouse)	Mdm2	NP_034916.1
Pan troglodytes (chimpanzee)	MDM2	XP_001155208.1
	MDM2	XP_001117336.2
Bos taurus (cattle)	MDM2	NP_001092577.1
Homo sapiens (human)	MDM2	NP_002383.2
Canis lupus familiaris (dog)	MDM2	NP_001003103.1

Gene Ontology
Bibliography

Related articles in PubMed

MicroRNA-188-3p is involved in sevoflurane anesthesia-induced neuroapoptosis by targeting MDM2.
Wang L, Zheng M, Wu S, Niu Z
Molecular medicine reports(2018 Jan)

Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7.
Zhao K, Yang Y, Zhang G, Wang C, Wang D, Wu M, Mei Y
EMBO reports(2018 Jan)

MDM2 mediates fibroblast activation and renal tubulointerstitial fibrosis via a p53-independent pathway.
Ye C, Tang H, Zhao Z, Lei CT, You CQ, Zhang J, Gao P, He FF, Chen S, Wang YM, Zhang C, Su H
American journal of physiology. Renal physiology312(4)F760-F768(2017 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MDM2 is involved in fibroblast activation, mediating renal tubulointerstitial fibrosis via a p53-independent pathway dependant on Notch1 ubiquitination and proteasome degradation.
Title: MDM2 mediates fibroblast activation and renal tubulointerstitial fibrosis via a p53-independent pathway.

Study showed that demonstrate that Mdm2 intertwines the mammalian target of RAPA, mTOR, and the receptor kinase GRK2 in regulating the desensitization/inactivation of the GPR17 receptor
Title: The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization.

High concentration glucose decrease the mRNA expression and cytosolic concentration of Mdm2.
Title: Hyperglycemia promotes p53-Mdm2 interaction but reduces p53 ubiquitination in RINm5F cells.

Explored expression of MMP-9 and MDM2 in the oncogenesis of lung cancer in rats.
Title: Expression and significance of MMP-9 and MDM2 in the oncogenesis of lung cancer in rats.

these data strongly suggested that SCYL1BP1 is a novel transcriptional activator in neurite outgrowth by directly modulating the Mdm2/p53-dependent pathway, which might play an important role in CNS development and axonal regeneration after injury.
Title: SCYL1BP1 modulates neurite outgrowth and regeneration by regulating the Mdm2/p53 pathway.

The following Mdm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mdm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06678	NM_001108099.1 Latest version!	Rattus norvegicus MDM2 proto-oncogene (Mdm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$272.30 $389.00
ORa30143	XM_006241383.2 Latest version!	Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa30143	XM_006241382.1 Latest version!	Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa47366	XM_008765396.1 Latest version!	Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa47366	XM_008765397.1 Latest version!	Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mdm2 ( NM_001108099.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101569.1 Rattus norvegicus MDM2 proto-oncogene (Mdm2), mRNA.

Price & Availability↑

CloneID	ORa06678
Clone ID Related Accession (Same CDS sequence)	NM_001108099.1
Accession Version	NM_001108099.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1377bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Rattus norvegicus(Norway rat)
Product	E3 ubiquitin-protein ligase Mdm2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473960.2. On or before Oct 4, 2007 this sequence version replaced XM_001080981.1, XM_235169.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTGCAATA CCAACATGTC TGTGTCTACC GAGGGTGCTG CAGGCACCTC ACAGATTCCA 
GCGTCGGAAC AAGAGACTCT GATTATATTT TATATTGGAC AGTATATTAT GACTAAAAGA 
TTATATGATG AGAAGCAGCA GCACATTGTG TATTGCTCAA ATGATCTCCT AGGAGATGTG 
TTCGGAGTCC CAAGTTTCTC TGTGAAGGAG CACAGGAAAA TATATGCAAT GATCTACAGA 
AACTTAGTGG TTGTAAGTCA ACAAGACTCT GGAACATCGC CGAGTGAGAG CAGATGTCAG 
CCTGAAGGTG GGAGTGACCT GAAGGACCCC GTGCAAGCAT CACAAGAAGA GAAACCTTCA 
TCTTCTGATG TAGTTTCTAG ACCATCTACC TCATCTAGAA GGAGAGCAAT TAGTGAAACA 
GAAGAGAACA CAGATGAACT ACCTGGGGAA CGACAGAGGA AGCGCCACAG AGCCCTGTCC 
TTTGATGAGA GCCTGGGTCT GTGTGTGCTC AGGGAGATAT GCTGTGAAAG AAGCAGCAGC 
AGCGAGGCCA CAGACACCCC CTCACATCAG GATCTTGATG ATGGCGTAAG TGACCATTCT 
GCTGATTGCC TGGATCAGGA TTCAGTTTCT GATCAATTCA GTGTAGAATT TGAAGTTGAG 
TCTCTTGACT CAGAAGATTA CAGCCTGAGT GATGAAGGGC ATGAGCTCTC AGATGAGGAT 
GATGAGGTCT ATCGGGTCAC AGTCTATCAG GCAGGAGAAA GCGATGCAGA CTCTTTTGAG 
GGAGATCCTG AAATTTCCTT AGCTGACTAT TGGAAATGCA CCTCGTGCAA TGAAATGAAT 
CCTCCCCTTC CATCACACTG CAACAGATGT TGGACCCTTC GTGAGAACTG GCTTCCAGAC 
GATAAGGGGA AAGATAAAGT GGAAATTTCT GAAAAAGCCA AACTGGAAAG CTCAGATCAG 
GCAGAAGAAG GCTTAGATGT GCCTGATGGC AAAAAAGTGA CAGAGGATGA TGCTAAGGAG 
TCATCTGCTG AGGATAGCGA GGAAAAAGTG GCCCAGATGC TCCTGTCACA GGAGAGTGAC 
GACTATTCCC AGCCGTCGAC TTCCAGTAGC ATTGTTTACA GCAGCCAAGA AAGTGGCAAA 
GAGTTGAAGG AGGACACACA AGACAAAGAG GAAAGTATGG AATCCAGCTT CTCTCTGAAC 
GCCATCGAGC CATGTGTGAT TTGCCAGGGG CGGCCTAAAA ATGGTTGCAT TGTTCACGGC 
AAAACCGGAC ACCTGATGTC ATGTTTCACG TGTGCAAAGA AGCTAAAGAA GAGGAATAAG 
CCCTGCCCCG TGTGCAGACA GCCGATCCAA ATGATTGTGC TCACGTACTT CAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101569.1
CDS	248..1624
Translation	MCNTNMSVSTEGAAGTSQIPASEQETLIIFYIGQYIMTKRLYDEKQQHIVYCSNDLLGDVFGVPSFSVKEHRKIYAMIYRNLVVVSQQDSGTSPSESRCQPEGGSDLKDPVQASQEEKPSSSDVVSRPSTSSRRRAISETEENTDELPGERQRKRHRALSFDESLGLCVLREICCERSSSSEATDTPSHQDLDDGVSDHSADCLDQDSVSDQFSVEFEVESLDSEDYSLSDEGHELSDEDDEVYRVTVYQAGESDADSFEGDPEISLADYWKCTSCNEMNPPLPSHCNRCWTLRENWLPDDKGKDKVEISEKAKLESSDQAEEGLDVPDGKKVTEDDAKESSAEDSEEKVAQMLLSQESDDYSQPSTSSSIVYSSQESGKELKEDTQDKEESMESSFSLNAIEPCVICQGRPKNGCIVHGKTGHLMSCFTCAKKLKKRNKPCPVCRQPIQMIVLTYFN

Target ORF information:

RefSeq Version	NM_001108099.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MDM2 proto-oncogene (Mdm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108099.1

ORF Insert Sequence:

ATGTGCAATA CCAACATGTC TGTGTCTACC GAGGGTGCTG CAGGCACCTC ACAGATTCCA 
GCGTCGGAAC AAGAGACTCT GATTATATTT TATATTGGAC AGTATATTAT GACTAAAAGA 
TTATATGATG AGAAGCAGCA GCACATTGTG TATTGCTCAA ATGATCTCCT AGGAGATGTG 
TTCGGAGTCC CAAGTTTCTC TGTGAAGGAG CACAGGAAAA TATATGCAAT GATCTACAGA 
AACTTAGTGG TTGTAAGTCA ACAAGACTCT GGAACATCGC CGAGTGAGAG CAGATGTCAG 
CCTGAAGGTG GGAGTGACCT GAAGGACCCC GTGCAAGCAT CACAAGAAGA GAAACCTTCA 
TCTTCTGATG TAGTTTCTAG ACCATCTACC TCATCTAGAA GGAGAGCAAT TAGTGAAACA 
GAAGAGAACA CAGATGAACT ACCTGGGGAA CGACAGAGGA AGCGCCACAG AGCCCTGTCC 
TTTGATGAGA GCCTGGGTCT GTGTGTGCTC AGGGAGATAT GCTGTGAAAG AAGCAGCAGC 
AGCGAGGCCA CAGACACCCC CTCACATCAG GATCTTGATG ATGGCGTAAG TGACCATTCT 
GCTGATTGCC TGGATCAGGA TTCAGTTTCT GATCAATTCA GTGTAGAATT TGAAGTTGAG 
TCTCTTGACT CAGAAGATTA CAGCCTGAGT GATGAAGGGC ATGAGCTCTC AGATGAGGAT 
GATGAGGTCT ATCGGGTCAC AGTCTATCAG GCAGGAGAAA GCGATGCAGA CTCTTTTGAG 
GGAGATCCTG AAATTTCCTT AGCTGACTAT TGGAAATGCA CCTCGTGCAA TGAAATGAAT 
CCTCCCCTTC CATCACACTG CAACAGATGT TGGACCCTTC GTGAGAACTG GCTTCCAGAC 
GATAAGGGGA AAGATAAAGT GGAAATTTCT GAAAAAGCCA AACTGGAAAG CTCAGATCAG 
GCAGAAGAAG GCTTAGATGT GCCTGATGGC AAAAAAGTGA CAGAGGATGA TGCTAAGGAG 
TCATCTGCTG AGGATAGCGA GGAAAAAGTG GCCCAGATGC TCCTGTCACA GGAGAGTGAC 
GACTATTCCC AGCCGTCGAC TTCCAGTAGC ATTGTTTACA GCAGCCAAGA AAGTGGCAAA 
GAGTTGAAGG AGGACACACA AGACAAAGAG GAAAGTATGG AATCCAGCTT CTCTCTGAAC 
GCCATCGAGC CATGTGTGAT TTGCCAGGGG CGGCCTAAAA ATGGTTGCAT TGTTCACGGC 
AAAACCGGAC ACCTGATGTC ATGTTTCACG TGTGCAAAGA AGCTAAAGAA GAGGAATAAG 
CCCTGCCCCG TGTGCAGACA GCCGATCCAA ATGATTGTGC TCACGTACTT CAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mdm2 ( XM_006241382.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241444.1 Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa30143
Clone ID Related Accession (Same CDS sequence)	XM_006241382.1 , XM_006241383.2
Accession Version	XM_006241382.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1452bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	E3 ubiquitin-protein ligase Mdm2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCAATA CCAACATGTC TGTGTCTACC GAGGGTGCTG CAGGCACCTC ACAGATTCCA 
GCGTCGGAAC AAGAGACTCT GGTTAGACCA AAACCATTGC TTTTGAAGTT GTTAAAGTCT 
GTTGGAGCAC AAAAAGATAT TTACACTATG AAAGAGATTA TATTTTATAT TGGACAGTAT 
ATTATGACTA AAAGATTATA TGATGAGAAG CAGCAGCACA TTGTGTATTG CTCAAATGAT 
CTCCTAGGAG ATGTGTTCGG AGTCCCAAGT TTCTCTGTGA AGGAGCACAG GAAAATATAT 
GCAATGATCT ACAGAAACTT AGTGGTTGTA AGTCAACAAG ACTCTGGAAC ATCGCCGAGT 
GAGAGCAGAT GTCAGCCTGA AGGTGGGAGT GACCTGAAGG ACCCCGTGCA AGCATCACAA 
GAAGAGAAAC CTTCATCTTC TGATGTAGTT TCTAGACCAT CTACCTCATC TAGAAGGAGA 
GCAATTAGTG AAACAGAAGA GAACACAGAT GAACTACCTG GGGAACGACA GAGGAAGCGC 
CACAGAGCCC TGTCCTTTGA TGAGAGCCTG GGTCTGTGTG TGCTCAGGGA GATATGCTGT 
GAAAGAAGCA GCAGCAGCGA GGCCACAGAC ACCCCCTCAC ATCAGGATCT TGATGATGGC 
GTAAGTGACC ATTCTGCTGA TTGCCTGGAT CAGGATTCAG TTTCTGATCA ATTCAGTGTA 
GAATTTGAAG TTGAGTCTCT TGACTCAGAA GATTACAGCC TGAGTGATGA AGGGCATGAG 
CTCTCAGATG AGGATGATGA GGTCTATCGG GTCACAGTCT ATCAGGCAGG AGAAAGCGAT 
GCAGACTCTT TTGAGGGAGA TCCTGAAATT TCCTTAGCTG ACTATTGGAA ATGCACCTCG 
TGCAATGAAA TGAATCCTCC CCTTCCATCA CACTGCAACA GATGTTGGAC CCTTCGTGAG 
AACTGGCTTC CAGACGATAA GGGGAAAGAT AAAGTGGAAA TTTCTGAAAA AGCCAAACTG 
GAAAGCTCAG ATCAGGCAGA AGAAGGCTTA GATGTGCCTG ATGGCAAAAA AGTGACAGAG 
GATGATGCTA AGGAGTCATC TGCTGAGGAT AGCGAGGAAA AAGTGGCCCA GATGCTCCTG 
TCACAGGAGA GTGACGACTA TTCCCAGCCG TCGACTTCCA GTAGCATTGT TTACAGCAGC 
CAAGAAAGTG GCAAAGAGTT GAAGGAGGAC ACACAAGACA AAGAGGAAAG TATGGAATCC 
AGCTTCTCTC TGAACGCCAT CGAGCCATGT GTGATTTGCC AGGGGCGGCC TAAAAATGGT 
TGCATTGTTC ACGGCAAAAC CGGACACCTG ATGTCATGTT TCACGTGTGC AAAGAAGCTA 
AAGAAGAGGA ATAAGCCCTG CCCCGTGTGC AGACAGCCGA TCCAAATGAT TGTGCTCACG 
TACTTCAACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241444.1
CDS	538..1989
Translation	MCNTNMSVSTEGAAGTSQIPASEQETLVRPKPLLLKLLKSVGAQKDIYTMKEIIFYIGQYIMTKRLYDEKQQHIVYCSNDLLGDVFGVPSFSVKEHRKIYAMIYRNLVVVSQQDSGTSPSESRCQPEGGSDLKDPVQASQEEKPSSSDVVSRPSTSSRRRAISETEENTDELPGERQRKRHRALSFDESLGLCVLREICCERSSSSEATDTPSHQDLDDGVSDHSADCLDQDSVSDQFSVEFEVESLDSEDYSLSDEGHELSDEDDEVYRVTVYQAGESDADSFEGDPEISLADYWKCTSCNEMNPPLPSHCNRCWTLRENWLPDDKGKDKVEISEKAKLESSDQAEEGLDVPDGKKVTEDDAKESSAEDSEEKVAQMLLSQESDDYSQPSTSSSIVYSSQESGKELKEDTQDKEESMESSFSLNAIEPCVICQGRPKNGCIVHGKTGHLMSCFTCAKKLKKRNKPCPVCRQPIQMIVLTYFN

Target ORF information:

RefSeq Version	XM_006241382.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006241382.1

ORF Insert Sequence:

ATGTGCAATA CCAACATGTC TGTGTCTACC GAGGGTGCTG CAGGCACCTC ACAGATTCCA 
GCGTCGGAAC AAGAGACTCT GGTTAGACCA AAACCATTGC TTTTGAAGTT GTTAAAGTCT 
GTTGGAGCAC AAAAAGATAT TTACACTATG AAAGAGATTA TATTTTATAT TGGACAGTAT 
ATTATGACTA AAAGATTATA TGATGAGAAG CAGCAGCACA TTGTGTATTG CTCAAATGAT 
CTCCTAGGAG ATGTGTTCGG AGTCCCAAGT TTCTCTGTGA AGGAGCACAG GAAAATATAT 
GCAATGATCT ACAGAAACTT AGTGGTTGTA AGTCAACAAG ACTCTGGAAC ATCGCCGAGT 
GAGAGCAGAT GTCAGCCTGA AGGTGGGAGT GACCTGAAGG ACCCCGTGCA AGCATCACAA 
GAAGAGAAAC CTTCATCTTC TGATGTAGTT TCTAGACCAT CTACCTCATC TAGAAGGAGA 
GCAATTAGTG AAACAGAAGA GAACACAGAT GAACTACCTG GGGAACGACA GAGGAAGCGC 
CACAGAGCCC TGTCCTTTGA TGAGAGCCTG GGTCTGTGTG TGCTCAGGGA GATATGCTGT 
GAAAGAAGCA GCAGCAGCGA GGCCACAGAC ACCCCCTCAC ATCAGGATCT TGATGATGGC 
GTAAGTGACC ATTCTGCTGA TTGCCTGGAT CAGGATTCAG TTTCTGATCA ATTCAGTGTA 
GAATTTGAAG TTGAGTCTCT TGACTCAGAA GATTACAGCC TGAGTGATGA AGGGCATGAG 
CTCTCAGATG AGGATGATGA GGTCTATCGG GTCACAGTCT ATCAGGCAGG AGAAAGCGAT 
GCAGACTCTT TTGAGGGAGA TCCTGAAATT TCCTTAGCTG ACTATTGGAA ATGCACCTCG 
TGCAATGAAA TGAATCCTCC CCTTCCATCA CACTGCAACA GATGTTGGAC CCTTCGTGAG 
AACTGGCTTC CAGACGATAA GGGGAAAGAT AAAGTGGAAA TTTCTGAAAA AGCCAAACTG 
GAAAGCTCAG ATCAGGCAGA AGAAGGCTTA GATGTGCCTG ATGGCAAAAA AGTGACAGAG 
GATGATGCTA AGGAGTCATC TGCTGAGGAT AGCGAGGAAA AAGTGGCCCA GATGCTCCTG 
TCACAGGAGA GTGACGACTA TTCCCAGCCG TCGACTTCCA GTAGCATTGT TTACAGCAGC 
CAAGAAAGTG GCAAAGAGTT GAAGGAGGAC ACACAAGACA AAGAGGAAAG TATGGAATCC 
AGCTTCTCTC TGAACGCCAT CGAGCCATGT GTGATTTGCC AGGGGCGGCC TAAAAATGGT 
TGCATTGTTC ACGGCAAAAC CGGACACCTG ATGTCATGTT TCACGTGTGC AAAGAAGCTA 
AAGAAGAGGA ATAAGCCCTG CCCCGTGTGC AGACAGCCGA TCCAAATGAT TGTGCTCACG 
TACTTCAACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mdm2 ( XM_006241383.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241445.1 Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa30143
Clone ID Related Accession (Same CDS sequence)	XM_006241382.1 , XM_006241383.2
Accession Version	XM_006241383.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1452bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	E3 ubiquitin-protein ligase Mdm2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006241383.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCAATA CCAACATGTC TGTGTCTACC GAGGGTGCTG CAGGCACCTC ACAGATTCCA 
GCGTCGGAAC AAGAGACTCT GGTTAGACCA AAACCATTGC TTTTGAAGTT GTTAAAGTCT 
GTTGGAGCAC AAAAAGATAT TTACACTATG AAAGAGATTA TATTTTATAT TGGACAGTAT 
ATTATGACTA AAAGATTATA TGATGAGAAG CAGCAGCACA TTGTGTATTG CTCAAATGAT 
CTCCTAGGAG ATGTGTTCGG AGTCCCAAGT TTCTCTGTGA AGGAGCACAG GAAAATATAT 
GCAATGATCT ACAGAAACTT AGTGGTTGTA AGTCAACAAG ACTCTGGAAC ATCGCCGAGT 
GAGAGCAGAT GTCAGCCTGA AGGTGGGAGT GACCTGAAGG ACCCCGTGCA AGCATCACAA 
GAAGAGAAAC CTTCATCTTC TGATGTAGTT TCTAGACCAT CTACCTCATC TAGAAGGAGA 
GCAATTAGTG AAACAGAAGA GAACACAGAT GAACTACCTG GGGAACGACA GAGGAAGCGC 
CACAGAGCCC TGTCCTTTGA TGAGAGCCTG GGTCTGTGTG TGCTCAGGGA GATATGCTGT 
GAAAGAAGCA GCAGCAGCGA GGCCACAGAC ACCCCCTCAC ATCAGGATCT TGATGATGGC 
GTAAGTGACC ATTCTGCTGA TTGCCTGGAT CAGGATTCAG TTTCTGATCA ATTCAGTGTA 
GAATTTGAAG TTGAGTCTCT TGACTCAGAA GATTACAGCC TGAGTGATGA AGGGCATGAG 
CTCTCAGATG AGGATGATGA GGTCTATCGG GTCACAGTCT ATCAGGCAGG AGAAAGCGAT 
GCAGACTCTT TTGAGGGAGA TCCTGAAATT TCCTTAGCTG ACTATTGGAA ATGCACCTCG 
TGCAATGAAA TGAATCCTCC CCTTCCATCA CACTGCAACA GATGTTGGAC CCTTCGTGAG 
AACTGGCTTC CAGACGATAA GGGGAAAGAT AAAGTGGAAA TTTCTGAAAA AGCCAAACTG 
GAAAGCTCAG ATCAGGCAGA AGAAGGCTTA GATGTGCCTG ATGGCAAAAA AGTGACAGAG 
GATGATGCTA AGGAGTCATC TGCTGAGGAT AGCGAGGAAA AAGTGGCCCA GATGCTCCTG 
TCACAGGAGA GTGACGACTA TTCCCAGCCG TCGACTTCCA GTAGCATTGT TTACAGCAGC 
CAAGAAAGTG GCAAAGAGTT GAAGGAGGAC ACACAAGACA AAGAGGAAAG TATGGAATCC 
AGCTTCTCTC TGAACGCCAT CGAGCCATGT GTGATTTGCC AGGGGCGGCC TAAAAATGGT 
TGCATTGTTC ACGGCAAAAC CGGACACCTG ATGTCATGTT TCACGTGTGC AAAGAAGCTA 
AAGAAGAGGA ATAAGCCCTG CCCCGTGTGC AGACAGCCGA TCCAAATGAT TGTGCTCACG 
TACTTCAACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241445.1
CDS	101..1552
Translation	MCNTNMSVSTEGAAGTSQIPASEQETLVRPKPLLLKLLKSVGAQKDIYTMKEIIFYIGQYIMTKRLYDEKQQHIVYCSNDLLGDVFGVPSFSVKEHRKIYAMIYRNLVVVSQQDSGTSPSESRCQPEGGSDLKDPVQASQEEKPSSSDVVSRPSTSSRRRAISETEENTDELPGERQRKRHRALSFDESLGLCVLREICCERSSSSEATDTPSHQDLDDGVSDHSADCLDQDSVSDQFSVEFEVESLDSEDYSLSDEGHELSDEDDEVYRVTVYQAGESDADSFEGDPEISLADYWKCTSCNEMNPPLPSHCNRCWTLRENWLPDDKGKDKVEISEKAKLESSDQAEEGLDVPDGKKVTEDDAKESSAEDSEEKVAQMLLSQESDDYSQPSTSSSIVYSSQESGKELKEDTQDKEESMESSFSLNAIEPCVICQGRPKNGCIVHGKTGHLMSCFTCAKKLKKRNKPCPVCRQPIQMIVLTYFN

Target ORF information:

RefSeq Version	XM_006241383.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006241383.2

ORF Insert Sequence:

ATGTGCAATA CCAACATGTC TGTGTCTACC GAGGGTGCTG CAGGCACCTC ACAGATTCCA 
GCGTCGGAAC AAGAGACTCT GGTTAGACCA AAACCATTGC TTTTGAAGTT GTTAAAGTCT 
GTTGGAGCAC AAAAAGATAT TTACACTATG AAAGAGATTA TATTTTATAT TGGACAGTAT 
ATTATGACTA AAAGATTATA TGATGAGAAG CAGCAGCACA TTGTGTATTG CTCAAATGAT 
CTCCTAGGAG ATGTGTTCGG AGTCCCAAGT TTCTCTGTGA AGGAGCACAG GAAAATATAT 
GCAATGATCT ACAGAAACTT AGTGGTTGTA AGTCAACAAG ACTCTGGAAC ATCGCCGAGT 
GAGAGCAGAT GTCAGCCTGA AGGTGGGAGT GACCTGAAGG ACCCCGTGCA AGCATCACAA 
GAAGAGAAAC CTTCATCTTC TGATGTAGTT TCTAGACCAT CTACCTCATC TAGAAGGAGA 
GCAATTAGTG AAACAGAAGA GAACACAGAT GAACTACCTG GGGAACGACA GAGGAAGCGC 
CACAGAGCCC TGTCCTTTGA TGAGAGCCTG GGTCTGTGTG TGCTCAGGGA GATATGCTGT 
GAAAGAAGCA GCAGCAGCGA GGCCACAGAC ACCCCCTCAC ATCAGGATCT TGATGATGGC 
GTAAGTGACC ATTCTGCTGA TTGCCTGGAT CAGGATTCAG TTTCTGATCA ATTCAGTGTA 
GAATTTGAAG TTGAGTCTCT TGACTCAGAA GATTACAGCC TGAGTGATGA AGGGCATGAG 
CTCTCAGATG AGGATGATGA GGTCTATCGG GTCACAGTCT ATCAGGCAGG AGAAAGCGAT 
GCAGACTCTT TTGAGGGAGA TCCTGAAATT TCCTTAGCTG ACTATTGGAA ATGCACCTCG 
TGCAATGAAA TGAATCCTCC CCTTCCATCA CACTGCAACA GATGTTGGAC CCTTCGTGAG 
AACTGGCTTC CAGACGATAA GGGGAAAGAT AAAGTGGAAA TTTCTGAAAA AGCCAAACTG 
GAAAGCTCAG ATCAGGCAGA AGAAGGCTTA GATGTGCCTG ATGGCAAAAA AGTGACAGAG 
GATGATGCTA AGGAGTCATC TGCTGAGGAT AGCGAGGAAA AAGTGGCCCA GATGCTCCTG 
TCACAGGAGA GTGACGACTA TTCCCAGCCG TCGACTTCCA GTAGCATTGT TTACAGCAGC 
CAAGAAAGTG GCAAAGAGTT GAAGGAGGAC ACACAAGACA AAGAGGAAAG TATGGAATCC 
AGCTTCTCTC TGAACGCCAT CGAGCCATGT GTGATTTGCC AGGGGCGGCC TAAAAATGGT 
TGCATTGTTC ACGGCAAAAC CGGACACCTG ATGTCATGTT TCACGTGTGC AAAGAAGCTA 
AAGAAGAGGA ATAAGCCCTG CCCCGTGTGC AGACAGCCGA TCCAAATGAT TGTGCTCACG 
TACTTCAACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mdm2 ( XM_008765397.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763619.1 Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X2, mRNA.

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CloneID	ORa47366
Clone ID Related Accession (Same CDS sequence)	XM_008765397.1 , XM_008765396.1
Accession Version	XM_008765397.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1524bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	E3 ubiquitin-protein ligase Mdm2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCAATA CCAACATGTC TGTGTCTACC GAGGGTGCTG CAGGCACCTC ACAGATTCCA 
GCGTCGGAAC AAGAGACTCT GGTTAGACCA AAACCATTGC TTTTGAAGTT GTTAAAGTCT 
GTTGGAGCAC AAAAAGATAT TTACACTATG AAAGAGTTTT ATCCAAGGAC TTCTTGGGCA 
TCCCTGGACC CCAGTTTGGA ACTTGTACAA CTGTGCTGGA ATGCTCAGAT TATATTTTAT 
ATTGGACAGT ATATTATGAC TAAAAGATTA TATGATGAGA AGCAGCAGCA CATTGTGTAT 
TGCTCAAATG ATCTCCTAGG AGATGTGTTC GGAGTCCCAA GTTTCTCTGT GAAGGAGCAC 
AGGAAAATAT ATGCAATGAT CTACAGAAAC TTAGTGGTTG TAAGTCAACA AGACTCTGGA 
ACATCGCCGA GTGAGAGCAG ATGTCAGCCT GAAGGTGGGA GTGACCTGAA GGACCCCGTG 
CAAGCATCAC AAGAAGAGAA ACCTTCATCT TCTGATGTAG TTTCTAGACC ATCTACCTCA 
TCTAGAAGGA GAGCAATTAG TGAAACAGAA GAGAACACAG ATGAACTACC TGGGGAACGA 
CAGAGGAAGC GCCACAGAGC CCTGTCCTTT GATGAGAGCC TGGGTCTGTG TGTGCTCAGG 
GAGATATGCT GTGAAAGAAG CAGCAGCAGC GAGGCCACAG ACACCCCCTC ACATCAGGAT 
CTTGATGATG GCGTAAGTGA CCATTCTGCT GATTGCCTGG ATCAGGATTC AGTTTCTGAT 
CAATTCAGTG TAGAATTTGA AGTTGAGTCT CTTGACTCAG AAGATTACAG CCTGAGTGAT 
GAAGGGCATG AGCTCTCAGA TGAGGATGAT GAGGTCTATC GGGTCACAGT CTATCAGGCA 
GGAGAAAGCG ATGCAGACTC TTTTGAGGGA GATCCTGAAA TTTCCTTAGC TGACTATTGG 
AAATGCACCT CGTGCAATGA AATGAATCCT CCCCTTCCAT CACACTGCAA CAGATGTTGG 
ACCCTTCGTG AGAACTGGCT TCCAGACGAT AAGGGGAAAG ATAAAGTGGA AATTTCTGAA 
AAAGCCAAAC TGGAAAGCTC AGATCAGGCA GAAGAAGGCT TAGATGTGCC TGATGGCAAA 
AAAGTGACAG AGGATGATGC TAAGGAGTCA TCTGCTGAGG ATAGCGAGGA AAAAGTGGCC 
CAGATGCTCC TGTCACAGGA GAGTGACGAC TATTCCCAGC CGTCGACTTC CAGTAGCATT 
GTTTACAGCA GCCAAGAAAG TGGCAAAGAG TTGAAGGAGG ACACACAAGA CAAAGAGGAA 
AGTATGGAAT CCAGCTTCTC TCTGAACGCC ATCGAGCCAT GTGTGATTTG CCAGGGGCGG 
CCTAAAAATG GTTGCATTGT TCACGGCAAA ACCGGACACC TGATGTCATG TTTCACGTGT 
GCAAAGAAGC TAAAGAAGAG GAATAAGCCC TGCCCCGTGT GCAGACAGCC GATCCAAATG 
ATTGTGCTCA CGTACTTCAA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763619.1
CDS	102..1625
Translation	MCNTNMSVSTEGAAGTSQIPASEQETLVRPKPLLLKLLKSVGAQKDIYTMKEFYPRTSWASLDPSLELVQLCWNAQIIFYIGQYIMTKRLYDEKQQHIVYCSNDLLGDVFGVPSFSVKEHRKIYAMIYRNLVVVSQQDSGTSPSESRCQPEGGSDLKDPVQASQEEKPSSSDVVSRPSTSSRRRAISETEENTDELPGERQRKRHRALSFDESLGLCVLREICCERSSSSEATDTPSHQDLDDGVSDHSADCLDQDSVSDQFSVEFEVESLDSEDYSLSDEGHELSDEDDEVYRVTVYQAGESDADSFEGDPEISLADYWKCTSCNEMNPPLPSHCNRCWTLRENWLPDDKGKDKVEISEKAKLESSDQAEEGLDVPDGKKVTEDDAKESSAEDSEEKVAQMLLSQESDDYSQPSTSSSIVYSSQESGKELKEDTQDKEESMESSFSLNAIEPCVICQGRPKNGCIVHGKTGHLMSCFTCAKKLKKRNKPCPVCRQPIQMIVLTYFN

Target ORF information:

RefSeq Version	XM_008765397.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765397.1

ORF Insert Sequence:

ATGTGCAATA CCAACATGTC TGTGTCTACC GAGGGTGCTG CAGGCACCTC ACAGATTCCA 
GCGTCGGAAC AAGAGACTCT GGTTAGACCA AAACCATTGC TTTTGAAGTT GTTAAAGTCT 
GTTGGAGCAC AAAAAGATAT TTACACTATG AAAGAGTTTT ATCCAAGGAC TTCTTGGGCA 
TCCCTGGACC CCAGTTTGGA ACTTGTACAA CTGTGCTGGA ATGCTCAGAT TATATTTTAT 
ATTGGACAGT ATATTATGAC TAAAAGATTA TATGATGAGA AGCAGCAGCA CATTGTGTAT 
TGCTCAAATG ATCTCCTAGG AGATGTGTTC GGAGTCCCAA GTTTCTCTGT GAAGGAGCAC 
AGGAAAATAT ATGCAATGAT CTACAGAAAC TTAGTGGTTG TAAGTCAACA AGACTCTGGA 
ACATCGCCGA GTGAGAGCAG ATGTCAGCCT GAAGGTGGGA GTGACCTGAA GGACCCCGTG 
CAAGCATCAC AAGAAGAGAA ACCTTCATCT TCTGATGTAG TTTCTAGACC ATCTACCTCA 
TCTAGAAGGA GAGCAATTAG TGAAACAGAA GAGAACACAG ATGAACTACC TGGGGAACGA 
CAGAGGAAGC GCCACAGAGC CCTGTCCTTT GATGAGAGCC TGGGTCTGTG TGTGCTCAGG 
GAGATATGCT GTGAAAGAAG CAGCAGCAGC GAGGCCACAG ACACCCCCTC ACATCAGGAT 
CTTGATGATG GCGTAAGTGA CCATTCTGCT GATTGCCTGG ATCAGGATTC AGTTTCTGAT 
CAATTCAGTG TAGAATTTGA AGTTGAGTCT CTTGACTCAG AAGATTACAG CCTGAGTGAT 
GAAGGGCATG AGCTCTCAGA TGAGGATGAT GAGGTCTATC GGGTCACAGT CTATCAGGCA 
GGAGAAAGCG ATGCAGACTC TTTTGAGGGA GATCCTGAAA TTTCCTTAGC TGACTATTGG 
AAATGCACCT CGTGCAATGA AATGAATCCT CCCCTTCCAT CACACTGCAA CAGATGTTGG 
ACCCTTCGTG AGAACTGGCT TCCAGACGAT AAGGGGAAAG ATAAAGTGGA AATTTCTGAA 
AAAGCCAAAC TGGAAAGCTC AGATCAGGCA GAAGAAGGCT TAGATGTGCC TGATGGCAAA 
AAAGTGACAG AGGATGATGC TAAGGAGTCA TCTGCTGAGG ATAGCGAGGA AAAAGTGGCC 
CAGATGCTCC TGTCACAGGA GAGTGACGAC TATTCCCAGC CGTCGACTTC CAGTAGCATT 
GTTTACAGCA GCCAAGAAAG TGGCAAAGAG TTGAAGGAGG ACACACAAGA CAAAGAGGAA 
AGTATGGAAT CCAGCTTCTC TCTGAACGCC ATCGAGCCAT GTGTGATTTG CCAGGGGCGG 
CCTAAAAATG GTTGCATTGT TCACGGCAAA ACCGGACACC TGATGTCATG TTTCACGTGT 
GCAAAGAAGC TAAAGAAGAG GAATAAGCCC TGCCCCGTGT GCAGACAGCC GATCCAAATG 
ATTGTGCTCA CGTACTTCAA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mdm2 ( XM_008765396.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763618.1 Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa47366
Clone ID Related Accession (Same CDS sequence)	XM_008765397.1 , XM_008765396.1
Accession Version	XM_008765396.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1524bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	E3 ubiquitin-protein ligase Mdm2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCAATA CCAACATGTC TGTGTCTACC GAGGGTGCTG CAGGCACCTC ACAGATTCCA 
GCGTCGGAAC AAGAGACTCT GGTTAGACCA AAACCATTGC TTTTGAAGTT GTTAAAGTCT 
GTTGGAGCAC AAAAAGATAT TTACACTATG AAAGAGTTTT ATCCAAGGAC TTCTTGGGCA 
TCCCTGGACC CCAGTTTGGA ACTTGTACAA CTGTGCTGGA ATGCTCAGAT TATATTTTAT 
ATTGGACAGT ATATTATGAC TAAAAGATTA TATGATGAGA AGCAGCAGCA CATTGTGTAT 
TGCTCAAATG ATCTCCTAGG AGATGTGTTC GGAGTCCCAA GTTTCTCTGT GAAGGAGCAC 
AGGAAAATAT ATGCAATGAT CTACAGAAAC TTAGTGGTTG TAAGTCAACA AGACTCTGGA 
ACATCGCCGA GTGAGAGCAG ATGTCAGCCT GAAGGTGGGA GTGACCTGAA GGACCCCGTG 
CAAGCATCAC AAGAAGAGAA ACCTTCATCT TCTGATGTAG TTTCTAGACC ATCTACCTCA 
TCTAGAAGGA GAGCAATTAG TGAAACAGAA GAGAACACAG ATGAACTACC TGGGGAACGA 
CAGAGGAAGC GCCACAGAGC CCTGTCCTTT GATGAGAGCC TGGGTCTGTG TGTGCTCAGG 
GAGATATGCT GTGAAAGAAG CAGCAGCAGC GAGGCCACAG ACACCCCCTC ACATCAGGAT 
CTTGATGATG GCGTAAGTGA CCATTCTGCT GATTGCCTGG ATCAGGATTC AGTTTCTGAT 
CAATTCAGTG TAGAATTTGA AGTTGAGTCT CTTGACTCAG AAGATTACAG CCTGAGTGAT 
GAAGGGCATG AGCTCTCAGA TGAGGATGAT GAGGTCTATC GGGTCACAGT CTATCAGGCA 
GGAGAAAGCG ATGCAGACTC TTTTGAGGGA GATCCTGAAA TTTCCTTAGC TGACTATTGG 
AAATGCACCT CGTGCAATGA AATGAATCCT CCCCTTCCAT CACACTGCAA CAGATGTTGG 
ACCCTTCGTG AGAACTGGCT TCCAGACGAT AAGGGGAAAG ATAAAGTGGA AATTTCTGAA 
AAAGCCAAAC TGGAAAGCTC AGATCAGGCA GAAGAAGGCT TAGATGTGCC TGATGGCAAA 
AAAGTGACAG AGGATGATGC TAAGGAGTCA TCTGCTGAGG ATAGCGAGGA AAAAGTGGCC 
CAGATGCTCC TGTCACAGGA GAGTGACGAC TATTCCCAGC CGTCGACTTC CAGTAGCATT 
GTTTACAGCA GCCAAGAAAG TGGCAAAGAG TTGAAGGAGG ACACACAAGA CAAAGAGGAA 
AGTATGGAAT CCAGCTTCTC TCTGAACGCC ATCGAGCCAT GTGTGATTTG CCAGGGGCGG 
CCTAAAAATG GTTGCATTGT TCACGGCAAA ACCGGACACC TGATGTCATG TTTCACGTGT 
GCAAAGAAGC TAAAGAAGAG GAATAAGCCC TGCCCCGTGT GCAGACAGCC GATCCAAATG 
ATTGTGCTCA CGTACTTCAA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763618.1
CDS	538..2061
Translation	MCNTNMSVSTEGAAGTSQIPASEQETLVRPKPLLLKLLKSVGAQKDIYTMKEFYPRTSWASLDPSLELVQLCWNAQIIFYIGQYIMTKRLYDEKQQHIVYCSNDLLGDVFGVPSFSVKEHRKIYAMIYRNLVVVSQQDSGTSPSESRCQPEGGSDLKDPVQASQEEKPSSSDVVSRPSTSSRRRAISETEENTDELPGERQRKRHRALSFDESLGLCVLREICCERSSSSEATDTPSHQDLDDGVSDHSADCLDQDSVSDQFSVEFEVESLDSEDYSLSDEGHELSDEDDEVYRVTVYQAGESDADSFEGDPEISLADYWKCTSCNEMNPPLPSHCNRCWTLRENWLPDDKGKDKVEISEKAKLESSDQAEEGLDVPDGKKVTEDDAKESSAEDSEEKVAQMLLSQESDDYSQPSTSSSIVYSSQESGKELKEDTQDKEESMESSFSLNAIEPCVICQGRPKNGCIVHGKTGHLMSCFTCAKKLKKRNKPCPVCRQPIQMIVLTYFN

Target ORF information:

RefSeq Version	XM_008765396.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MDM2 proto-oncogene (Mdm2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765396.1

ORF Insert Sequence:

ATGTGCAATA CCAACATGTC TGTGTCTACC GAGGGTGCTG CAGGCACCTC ACAGATTCCA 
GCGTCGGAAC AAGAGACTCT GGTTAGACCA AAACCATTGC TTTTGAAGTT GTTAAAGTCT 
GTTGGAGCAC AAAAAGATAT TTACACTATG AAAGAGTTTT ATCCAAGGAC TTCTTGGGCA 
TCCCTGGACC CCAGTTTGGA ACTTGTACAA CTGTGCTGGA ATGCTCAGAT TATATTTTAT 
ATTGGACAGT ATATTATGAC TAAAAGATTA TATGATGAGA AGCAGCAGCA CATTGTGTAT 
TGCTCAAATG ATCTCCTAGG AGATGTGTTC GGAGTCCCAA GTTTCTCTGT GAAGGAGCAC 
AGGAAAATAT ATGCAATGAT CTACAGAAAC TTAGTGGTTG TAAGTCAACA AGACTCTGGA 
ACATCGCCGA GTGAGAGCAG ATGTCAGCCT GAAGGTGGGA GTGACCTGAA GGACCCCGTG 
CAAGCATCAC AAGAAGAGAA ACCTTCATCT TCTGATGTAG TTTCTAGACC ATCTACCTCA 
TCTAGAAGGA GAGCAATTAG TGAAACAGAA GAGAACACAG ATGAACTACC TGGGGAACGA 
CAGAGGAAGC GCCACAGAGC CCTGTCCTTT GATGAGAGCC TGGGTCTGTG TGTGCTCAGG 
GAGATATGCT GTGAAAGAAG CAGCAGCAGC GAGGCCACAG ACACCCCCTC ACATCAGGAT 
CTTGATGATG GCGTAAGTGA CCATTCTGCT GATTGCCTGG ATCAGGATTC AGTTTCTGAT 
CAATTCAGTG TAGAATTTGA AGTTGAGTCT CTTGACTCAG AAGATTACAG CCTGAGTGAT 
GAAGGGCATG AGCTCTCAGA TGAGGATGAT GAGGTCTATC GGGTCACAGT CTATCAGGCA 
GGAGAAAGCG ATGCAGACTC TTTTGAGGGA GATCCTGAAA TTTCCTTAGC TGACTATTGG 
AAATGCACCT CGTGCAATGA AATGAATCCT CCCCTTCCAT CACACTGCAA CAGATGTTGG 
ACCCTTCGTG AGAACTGGCT TCCAGACGAT AAGGGGAAAG ATAAAGTGGA AATTTCTGAA 
AAAGCCAAAC TGGAAAGCTC AGATCAGGCA GAAGAAGGCT TAGATGTGCC TGATGGCAAA 
AAAGTGACAG AGGATGATGC TAAGGAGTCA TCTGCTGAGG ATAGCGAGGA AAAAGTGGCC 
CAGATGCTCC TGTCACAGGA GAGTGACGAC TATTCCCAGC CGTCGACTTC CAGTAGCATT 
GTTTACAGCA GCCAAGAAAG TGGCAAAGAG TTGAAGGAGG ACACACAAGA CAAAGAGGAA 
AGTATGGAAT CCAGCTTCTC TCTGAACGCC ATCGAGCCAT GTGTGATTTG CCAGGGGCGG 
CCTAAAAATG GTTGCATTGT TCACGGCAAA ACCGGACACC TGATGTCATG TTTCACGTGT 
GCAAAGAAGC TAAAGAAGAG GAATAAGCCC TGCCCCGTGT GCAGACAGCC GATCCAAATG 
ATTGTGCTCA CGTACTTCAA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MicroRNA-188-3p is involved in sevoflurane anesthesia-induced neuroapoptosis by targeting MDM2.
Molecular medicine reports(2018 Jan)
Wang L,Zheng M,Wu S,Niu Z

Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7.
EMBO reports(2018 Jan)
Zhao K,Yang Y,Zhang G,Wang C,Wang D,Wu M,Mei Y

MDM2 mediates fibroblast activation and renal tubulointerstitial fibrosis via a p53-independent pathway.
American journal of physiology. Renal physiology312(4)F760-F768(2017 Apr)
Ye C,Tang H,Zhao Z,Lei CT,You CQ,Zhang J,Gao P,He FF,Chen S,Wang YM,Zhang C,Su H

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Mdm2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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