Kdm3a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kdm3a
Entrez Gene ID	312440
Full Name	lysine demethylase 3A
Synonyms	Jmjd1,Jmjd1a
General protein information	Preferred Names lysine demethylase 3A Names lysine-specific demethylase 3A jmjC domain-containing histone demethylation protein 2A jumonji domain containing 1A jumonji domain-containing protein 1A lysine (K)-specific demethylase 3A probable zinc finger protein testis-specific gene A protein zinc finger protein TSGA
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q31
Summary	may play a role in spermatogenesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006236639.2	XP_006236701.1	lysine-specific demethylase 3A isoform X1
XM_006236637.3	XP_006236699.1	lysine-specific demethylase 3A isoform X1
NM_175764.2	NP_786940.1	lysine-specific demethylase 3A

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	kdm3a	XP_004911336.1
Gallus gallus (chicken)	KDM3A	NP_001012909.1
Homo sapiens (human)	KDM3A	NP_001140160.1
	KDM3A	XP_001086319.2
Pan troglodytes (chimpanzee)	KDM3A	XP_003309155.1
Canis lupus familiaris (dog)	KDM3A	XP_532973.3
Rattus norvegicus (Norway rat)	Kdm3a	NP_786940.1
Bos taurus (cattle)	KDM3A	NP_001179801.1
Mus musculus (house mouse)	Kdm3a	NP_766589.1

Gene Ontology
Bibliography

Related articles in PubMed

KDM3A inhibition attenuates high concentration insulin?induced vascular smooth muscle cell injury by suppressing MAPK/NF??B pathways.
Zhang BF, Jiang H, Chen J, Guo X, Hu Q, Yang S
International journal of molecular medicine41(3)1265-1274(2018 Mar)

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.
Tumber A, Nuzzi A, Hookway ES, Hatch SB, Velupillai S, Johansson C, Kawamura A, Savitsky P, Yapp C, Szykowska A, Wu N, Bountra C, Strain-Damerell C, Burgess-Brown NA, Ruda GF, Fedorov O, Munro S, England KS, Nowak RP, Schofield CJ, La Thangue NB, Pawlyn C, Davies F, Morgan G, Athanasou N, M?ller S, Oppermann U, Brennan PE
Cell chemical biology24(3)371-380(2017 Mar)

Histone demethylase KDM3a, a novel regulator of vascular smooth muscle cells, controls vascular neointimal hyperplasia in diabetic rats.
Chen J, Zhang J, Yang J, Xu L, Hu Q, Xu C, Yang S, Jiang H
Atherosclerosis257152-163(2017 Feb)

HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia.
Chakraborty D, Cui W, Rosario GX, Scott RL, Dhakal P, Renaud SJ, Tachibana M, Rumi MA, Mason CW, Krieg AJ, Soares MJ
Proceedings of the National Academy of Sciences of the United States of America113(46)E7212-E7221(2016 Nov)

The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma.
Parrish JK, Sechler M, Winn RA, Jedlicka P
Oncogene34(2)257-62(2015 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Histone demethylase KDM3a promotes vascular neointimal hyperplasia in diabetic rats via AGTR1 and ROCK2 signaling pathways.
Title: Histone demethylase KDM3a, a novel regulator of vascular smooth muscle cells, controls vascular neointimal hyperplasia in diabetic rats.

Despite these differences in rats, genetic knockout of Kdm3a in mice resulted in no dramatic effect on immune system development and activation or EAE susceptibility and severity
Title: A silent exonic SNP in kdm3a affects nucleic acids structure but does not regulate experimental autoimmune encephalomyelitis.

The following Kdm3a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kdm3a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa03964	NM_175764.2 Latest version!	Rattus norvegicus lysine demethylase 3A (Kdm3a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$895.30 $1279.00
ORa27332	XM_006236637.3 Latest version!	Rattus norvegicus lysine demethylase 3A (Kdm3a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
ORa27332	XM_006236639.2 Latest version!	Rattus norvegicus lysine demethylase 3A (Kdm3a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kdm3a ( NM_175764.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_786940.1 Rattus norvegicus lysine demethylase 3A (Kdm3a), mRNA.

Price & Availability↑

CloneID	ORa03964
Clone ID Related Accession (Same CDS sequence)	NM_175764.2
Accession Version	NM_175764.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3645bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	lysine-specific demethylase 3A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X59993.1. On Jun 3, 2003 this sequence version replaced NM_175764.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X59993.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTACAAAT CTCTACTAGA CAAAGCTGGC TTGGGATCCA TAACTTCTGT TCGCTTCCTT 
GGAGATCAGC AAAGTGTATT TGTTTCCAAA GACCTTTTGA AACCTATACA GGATGTAAAC 
AGTCTTCGGC TTTCCCTTAC TGATAATCAG ACGGTCAGTA AAGAGTTTCA AGCTTTGATT 
GTAAAACATT TGGATGAAAG CCATCTTTTA CAAGGTGACA AGAACCTTGT TGGTTCAGAA 
GTAAGAATTT ATAGCTTGGA TCCATCTACT CAGTGGTTTT CAGCAACTGT TGTACATGGA 
AACCCCTCAT CCAAAACTCT TCAAGTCAAC TGTGAGGAGA TTCCAGCGCT GAAAATTGTT 
GATCCAGCAC TGATTCACGT TGAAGTTGTA CACGATAATT TTGTAACGTG TGGTAATTCT 
ACAAGAATTG GAGCTGTGAA ACGCAAGTCT TCTGAGAATA ATGGAAGTTC AGTTTCTAAA 
CAAGCAAAAT CTTGCTCTGA GGTCTCTCCC AGTATGTGTC CTGTACAGTC TGTTCCCACA 
ACAGTGTGTA AGGAGATCCT GCTTGGCTGT ACTGCAGCAA CCCCATCTAG CAACAGACAG 
CAGAACACTC CCCAGGCAGC CAATTCTCCA CCTAACATTG GAGCAAAACT TCCTCAAGGA 
TGTCACAAGC AGAGTTTACC AGAAGAAATT TCTTCCTGTC TAAATACAAA ATCTGAAGTA 
CTGAGAACAA AACCAGATGT TTGCAAAGCA GGATTACTTT CTTCAAAATC TTCTCAGGTT 
GGAGCTGGAG ACTTGAAAAT TCTGAGTGAG CCCAAAGGTA GCTGTATCCA GCCTAAAACA 
AACACTGATC AGGAGAGCAG ACTGGAGTCT ACTCCACAAC CAGTCACTGG CCTTACAAAG 
GAGTGCTTGG TTACAAAGAC TTCCTCTAAG GCAGAACTGG ACAATGCCAC TGCTCCTGAA 
CTGCAGAAGC GTCTAGAGCA CACAGCTTCC ACACCCGATG GTCTTTCAGA CAAGCCAGAA 
GTGGAAGCAG GTGTCACTAG GCTTAATAGC TGTTCAGAAA AGAAGGTTGG ACCTTCAGAT 
TTAGGTTCGC AGTCACAGAA TTTAAAGGAA ACTTCAGTAA AAGTCGATCA TGACAGCTGT 
TGTACAAGAA GCAGTAATAA AACCCAGACT CCCCCAGCCC GGAAGTCAGT TTTGACAGAC 
CCAGATAAAC TCAAGAAGCT ACAGCAGAGT GGAGAGGCCT TTGTTCAGGA TGACTCCTGT 
GTTAACATCG TGGCACAGCT GCCCAAGTGT CGGGAGTGTC GATTAGACAG CCTGCGCAAG 
GATAAGGACC AGCAGAAAGA CTCGCCAGTG TTCTGTCGCT TTTTTCACTT CAGGAGGTTA 
CAATTCAACA AACATGGTGT TCTGCGGGTA GAAGGCTTCT TAACACCAAA CAAGTACGAC 
AGTGAAGCGA TTGGCTTGTG GCTGCCTTTG ACCAAAAATG TTGTGGGGAC CGATTTGGAC 
ACAGCAAAGT ATATCCTGGC CAATATTGGA GACCACTTCT GTCAAATGGT GATTTCTGAG 
AAGGAGGCTA TGTCAACTAT TGAGCCACAC AGGCAGGTTG CTTGGAAACG AGCTGTCAAA 
GGAGTTAGAG AAATGTGTGA TGTGTGTGAC ACAACCATTT TCAACCTGCA CTGGGTGTGC 
CCTCGGTGTG GGTTTGGAGT GTGTGTAGAT TGCTACCGGC TGAAGAGGAA GAATTGCCAA 
CAGGGGGCTG CCTACAAGAC TTTCTCTTGG ATAAGGTGTG TGAAGAGTCA AATACATGAG 
CCTGAGAACC TGATGCCCAC GCAGATTATT CCTGGCAAAG CCCTCTACGA TGTTGGAGAC 
ATTGTGCATT CTGTCAGAGC AAAATGGGGT ATAAAGGCCA ATTGTCCCTG CTCCAACAGG 
CAGTTCAAGC TCTTCTCGAA GCCAGCCTTA AAGGAAGACC TGAAGCAGGC ATCCTTGTCT 
GGAGAAAAAC CAAGTCTCGG CACCATGGTA CAGCAAAGCT CCCCTGTGTT GGAGCCAGCA 
GCCGTGTGTG GGGAAGCACC CTCCAAGCCA GCCAGCAATG TGAAGCCCAT CTGTCCAGCC 
AACACATCCC CTTTAAACTG GCTGGCTGAC CTGACCAGTG GCAATGTCAA CAAGGAAAAC 
AAGGAAAAAC AGCTGACTAT GCCAATTTTA AAGAACGAAA TCAAATGCCT TCCACCCTTG 
CCTCCTCTGA ACAAGTCCAG CACTGTCCTC CATACTTTTA ACAGCACAAT TTTGACACCC 
GTGAGCAACA ATAATTCTGG TTTTCTTCGA AATCTTTTGA ATTCATCCAC AGGAAAGACA 
GAAAATGGAC TAAAAAACAC ACCCAAAATC CTTGATGATA TCTTTGCCTC TTTGGTACAA 
AACAAGACTT CTTCTGACTT ATCCAAGAGG CCTCAAGGAC TGACGATCAA GCCTAGCATT 
CTTGGTTTTG ACACTCCTCA CTACTGGCTG TGTGACAACC GCCTGCTGTG CTTGCAAGAC 
CCCAACAATA AGAGCAATTG GAATGTCTTT AGGGAATGCT GGAAACAGGG GCAGCCAGTG 
ATGGTGTCGG GAGTGCATCA TAAATTAAAC ACTGAACTCT GGAAACCCGA GTCCTTCAGG 
AAAGAGTTTG GCGAGCAAGA AGTAGACCTA GTCAATTGTA GGACCAATGA AATCATCACA 
GGAGCCACAG TGGGAGACTT CTGGGATGGA TTTGAAGATG TTCCAAACCG TTTGAAAAAC 
GAAAAAGAAA AAGAACCAAT GGTGTTGAAA CTTAAGGACT GGCCGCCAGG AGAAGACTTT 
AGAGATATGA TGCCTTCCAG GTTTGATGAT CTGATGGCCA ACATTCCACT GCCTGAGTAT 
ACCAGGCGAG ATGGCAAACT GAACCTGGCC TCTAGACTGC CAAACTACTT TGTACGGCCA 
GACCTGGGCC CCAAGATGTA CAATGCTTAT GGATTGATCA CTCCAGAAGA TCGGAAATAT 
GGGACCACGA ATCTTCACTT AGATGTATCT GATGCAGCCA ATGTCATGGT TTATGTGGGA 
ATTCCCAAAG GACAGTGTGA ACAAGAGGAA GAAGTCCTTA GAACCATCCA AGATGGAGAT 
TCGGATGAAC TCACAATCAA GCGATTTATT GAAGGAAAAG AGAAGCCAGG CGCCCTTTGG 
CACATATATG CTGCTAAAGA CACAGAAAAG ATAAGAGAAT TCCTTAAAAA GGTATCTGAA 
GAGCAGGGTC AAGAAAACCC CGCAGACCAT GATCCTATTC ATGATCAGAG CTGGTATTTA 
GACCGATCAC TGAGAAAGCG CCTTTATCAA GAGTATGGAG TTCAAGGCTG GGCTATTGTA 
CAATTTCTTG GCGATGTGGT GTTTATCCCG GCAGGAGCTC CACATCAGGT TCATAACTTA 
TACAGCTGTA TCAAAGTCGC TGAAGACTTC GTGTCTCCAG AGCATGTGAA ACACTGCTTC 
TGGCTCACTC AGGAATTCCG TCACTTGTCA CAGACTCATA CCAACCACGA AGATAAACTG 
CAGGTAAAGA ATGTTATCTA CCATGCAGTA AAAGATGCAG TTGCTATGCT GAAAGCAGTG 
AATCCAGTTT GGGCAAATGT TAACTCCTCT GCACATTGGA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_786940.1
CDS	300..3944
Translation	MYKSLLDKAGLGSITSVRFLGDQQSVFVSKDLLKPIQDVNSLRLSLTDNQTVSKEFQALIVKHLDESHLLQGDKNLVGSEVRIYSLDPSTQWFSATVVHGNPSSKTLQVNCEEIPALKIVDPALIHVEVVHDNFVTCGNSTRIGAVKRKSSENNGSSVSKQAKSCSEVSPSMCPVQSVPTTVCKEILLGCTAATPSSNRQQNTPQAANSPPNIGAKLPQGCHKQSLPEEISSCLNTKSEVLRTKPDVCKAGLLSSKSSQVGAGDLKILSEPKGSCIQPKTNTDQESRLESTPQPVTGLTKECLVTKTSSKAELDNATAPELQKRLEHTASTPDGLSDKPEVEAGVTRLNSCSEKKVGPSDLGSQSQNLKETSVKVDHDSCCTRSSNKTQTPPARKSVLTDPDKLKKLQQSGEAFVQDDSCVNIVAQLPKCRECRLDSLRKDKDQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDSEAIGLWLPLTKNVVGTDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRLKRKNCQQGAAYKTFSWIRCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPALKEDLKQASLSGEKPSLGTMVQQSSPVLEPAAVCGEAPSKPASNVKPICPANTSPLNWLADLTSGNVNKENKEKQLTMPILKNEIKCLPPLPPLNKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGLKNTPKILDDIFASLVQNKTSSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNKSNWNVFRECWKQGQPVMVSGVHHKLNTELWKPESFRKEFGEQEVDLVNCRTNEIITGATVGDFWDGFEDVPNRLKNEKEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGKLNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQCEQEEEVLRTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQENPADHDPIHDQSWYLDRSLRKRLYQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRHLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKAVNPVWANVNSSAHWR

Target ORF information:

RefSeq Version	NM_175764.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysine demethylase 3A (Kdm3a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175764.2

ORF Insert Sequence:

ATGTACAAAT CTCTACTAGA CAAAGCTGGC TTGGGATCCA TAACTTCTGT TCGCTTCCTT 
GGAGATCAGC AAAGTGTATT TGTTTCCAAA GACCTTTTGA AACCTATACA GGATGTAAAC 
AGTCTTCGGC TTTCCCTTAC TGATAATCAG ACGGTCAGTA AAGAGTTTCA AGCTTTGATT 
GTAAAACATT TGGATGAAAG CCATCTTTTA CAAGGTGACA AGAACCTTGT TGGTTCAGAA 
GTAAGAATTT ATAGCTTGGA TCCATCTACT CAGTGGTTTT CAGCAACTGT TGTACATGGA 
AACCCCTCAT CCAAAACTCT TCAAGTCAAC TGTGAGGAGA TTCCAGCGCT GAAAATTGTT 
GATCCAGCAC TGATTCACGT TGAAGTTGTA CACGATAATT TTGTAACGTG TGGTAATTCT 
ACAAGAATTG GAGCTGTGAA ACGCAAGTCT TCTGAGAATA ATGGAAGTTC AGTTTCTAAA 
CAAGCAAAAT CTTGCTCTGA GGTCTCTCCC AGTATGTGTC CTGTACAGTC TGTTCCCACA 
ACAGTGTGTA AGGAGATCCT GCTTGGCTGT ACTGCAGCAA CCCCATCTAG CAACAGACAG 
CAGAACACTC CCCAGGCAGC CAATTCTCCA CCTAACATTG GAGCAAAACT TCCTCAAGGA 
TGTCACAAGC AGAGTTTACC AGAAGAAATT TCTTCCTGTC TAAATACAAA ATCTGAAGTA 
CTGAGAACAA AACCAGATGT TTGCAAAGCA GGATTACTTT CTTCAAAATC TTCTCAGGTT 
GGAGCTGGAG ACTTGAAAAT TCTGAGTGAG CCCAAAGGTA GCTGTATCCA GCCTAAAACA 
AACACTGATC AGGAGAGCAG ACTGGAGTCT ACTCCACAAC CAGTCACTGG CCTTACAAAG 
GAGTGCTTGG TTACAAAGAC TTCCTCTAAG GCAGAACTGG ACAATGCCAC TGCTCCTGAA 
CTGCAGAAGC GTCTAGAGCA CACAGCTTCC ACACCCGATG GTCTTTCAGA CAAGCCAGAA 
GTGGAAGCAG GTGTCACTAG GCTTAATAGC TGTTCAGAAA AGAAGGTTGG ACCTTCAGAT 
TTAGGTTCGC AGTCACAGAA TTTAAAGGAA ACTTCAGTAA AAGTCGATCA TGACAGCTGT 
TGTACAAGAA GCAGTAATAA AACCCAGACT CCCCCAGCCC GGAAGTCAGT TTTGACAGAC 
CCAGATAAAC TCAAGAAGCT ACAGCAGAGT GGAGAGGCCT TTGTTCAGGA TGACTCCTGT 
GTTAACATCG TGGCACAGCT GCCCAAGTGT CGGGAGTGTC GATTAGACAG CCTGCGCAAG 
GATAAGGACC AGCAGAAAGA CTCGCCAGTG TTCTGTCGCT TTTTTCACTT CAGGAGGTTA 
CAATTCAACA AACATGGTGT TCTGCGGGTA GAAGGCTTCT TAACACCAAA CAAGTACGAC 
AGTGAAGCGA TTGGCTTGTG GCTGCCTTTG ACCAAAAATG TTGTGGGGAC CGATTTGGAC 
ACAGCAAAGT ATATCCTGGC CAATATTGGA GACCACTTCT GTCAAATGGT GATTTCTGAG 
AAGGAGGCTA TGTCAACTAT TGAGCCACAC AGGCAGGTTG CTTGGAAACG AGCTGTCAAA 
GGAGTTAGAG AAATGTGTGA TGTGTGTGAC ACAACCATTT TCAACCTGCA CTGGGTGTGC 
CCTCGGTGTG GGTTTGGAGT GTGTGTAGAT TGCTACCGGC TGAAGAGGAA GAATTGCCAA 
CAGGGGGCTG CCTACAAGAC TTTCTCTTGG ATAAGGTGTG TGAAGAGTCA AATACATGAG 
CCTGAGAACC TGATGCCCAC GCAGATTATT CCTGGCAAAG CCCTCTACGA TGTTGGAGAC 
ATTGTGCATT CTGTCAGAGC AAAATGGGGT ATAAAGGCCA ATTGTCCCTG CTCCAACAGG 
CAGTTCAAGC TCTTCTCGAA GCCAGCCTTA AAGGAAGACC TGAAGCAGGC ATCCTTGTCT 
GGAGAAAAAC CAAGTCTCGG CACCATGGTA CAGCAAAGCT CCCCTGTGTT GGAGCCAGCA 
GCCGTGTGTG GGGAAGCACC CTCCAAGCCA GCCAGCAATG TGAAGCCCAT CTGTCCAGCC 
AACACATCCC CTTTAAACTG GCTGGCTGAC CTGACCAGTG GCAATGTCAA CAAGGAAAAC 
AAGGAAAAAC AGCTGACTAT GCCAATTTTA AAGAACGAAA TCAAATGCCT TCCACCCTTG 
CCTCCTCTGA ACAAGTCCAG CACTGTCCTC CATACTTTTA ACAGCACAAT TTTGACACCC 
GTGAGCAACA ATAATTCTGG TTTTCTTCGA AATCTTTTGA ATTCATCCAC AGGAAAGACA 
GAAAATGGAC TAAAAAACAC ACCCAAAATC CTTGATGATA TCTTTGCCTC TTTGGTACAA 
AACAAGACTT CTTCTGACTT ATCCAAGAGG CCTCAAGGAC TGACGATCAA GCCTAGCATT 
CTTGGTTTTG ACACTCCTCA CTACTGGCTG TGTGACAACC GCCTGCTGTG CTTGCAAGAC 
CCCAACAATA AGAGCAATTG GAATGTCTTT AGGGAATGCT GGAAACAGGG GCAGCCAGTG 
ATGGTGTCGG GAGTGCATCA TAAATTAAAC ACTGAACTCT GGAAACCCGA GTCCTTCAGG 
AAAGAGTTTG GCGAGCAAGA AGTAGACCTA GTCAATTGTA GGACCAATGA AATCATCACA 
GGAGCCACAG TGGGAGACTT CTGGGATGGA TTTGAAGATG TTCCAAACCG TTTGAAAAAC 
GAAAAAGAAA AAGAACCAAT GGTGTTGAAA CTTAAGGACT GGCCGCCAGG AGAAGACTTT 
AGAGATATGA TGCCTTCCAG GTTTGATGAT CTGATGGCCA ACATTCCACT GCCTGAGTAT 
ACCAGGCGAG ATGGCAAACT GAACCTGGCC TCTAGACTGC CAAACTACTT TGTACGGCCA 
GACCTGGGCC CCAAGATGTA CAATGCTTAT GGATTGATCA CTCCAGAAGA TCGGAAATAT 
GGGACCACGA ATCTTCACTT AGATGTATCT GATGCAGCCA ATGTCATGGT TTATGTGGGA 
ATTCCCAAAG GACAGTGTGA ACAAGAGGAA GAAGTCCTTA GAACCATCCA AGATGGAGAT 
TCGGATGAAC TCACAATCAA GCGATTTATT GAAGGAAAAG AGAAGCCAGG CGCCCTTTGG 
CACATATATG CTGCTAAAGA CACAGAAAAG ATAAGAGAAT TCCTTAAAAA GGTATCTGAA 
GAGCAGGGTC AAGAAAACCC CGCAGACCAT GATCCTATTC ATGATCAGAG CTGGTATTTA 
GACCGATCAC TGAGAAAGCG CCTTTATCAA GAGTATGGAG TTCAAGGCTG GGCTATTGTA 
CAATTTCTTG GCGATGTGGT GTTTATCCCG GCAGGAGCTC CACATCAGGT TCATAACTTA 
TACAGCTGTA TCAAAGTCGC TGAAGACTTC GTGTCTCCAG AGCATGTGAA ACACTGCTTC 
TGGCTCACTC AGGAATTCCG TCACTTGTCA CAGACTCATA CCAACCACGA AGATAAACTG 
CAGGTAAAGA ATGTTATCTA CCATGCAGTA AAAGATGCAG TTGCTATGCT GAAAGCAGTG 
AATCCAGTTT GGGCAAATGT TAACTCCTCT GCACATTGGA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kdm3a ( XM_006236639.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236701.1 Rattus norvegicus lysine demethylase 3A (Kdm3a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa27332
Clone ID Related Accession (Same CDS sequence)	XM_006236639.2 , XM_006236637.3
Accession Version	XM_006236639.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lysine-specific demethylase 3A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006236639.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCTCA CGCTCGGAGA AAGTTGGCCA GTATTGGTGG GGAAGCGATT CCTCAGTCTG 
TCCGCAGCTG AAGGCAGCGA CGGCGGCCAC GACAACTGGG ACTTGGAGCG CGTTGCAGAG 
TGGCCCTGGC TGTCCGGGAC CATTCGAGCT GTTTCTCACA CTGACGTTAC CAAGAAAGAT 
TTGAAGGTTT GTGTGGAGTT TGATGGAGAG TCTTGGAGAA AGAGAAGATG GATAGATGTC 
TACAGCCTTC TAAGAAGAGC ATTTTTAGTA GAACATAACC TGGTTCTGGC AGAACGAAAA 
TCACCTGAGA TTCCTGAGCA AGTTATTCAG TGGCCTGCAA TAATGTACAA ATCTCTACTA 
GACAAAGCTG GCTTGGGATC CATAACTTCT GTTCGCTTCC TTGGAGATCA GCAAAGTGTA 
TTTGTTTCCA AAGACCTTTT GAAACCTATA CAGGATGTAA ACAGTCTTCG GCTTTCCCTT 
ACTGATAATC AGACGGTCAG TAAAGAGTTT CAAGCTTTGA TTGTAAAACA TTTGGATGAA 
AGCCATCTTT TACAAGGTGA CAAGAACCTT GTTGGTTCAG AAGTAAGAAT TTATAGCTTG 
GATCCATCTA CTCAGTGGTT TTCAGCAACT GTTGTACATG GAAACCCCTC ATCCAAAACT 
CTTCAAGTCA ACTGTGAGGA GATTCCAGCG CTGAAAATTG TTGATCCAGC ACTGATTCAC 
GTTGAAGTTG TACACGATAA TTTTGTAACG TGTGGTAATT CTACAAGAAT TGGAGCTGTG 
AAACGCAAGT CTTCTGAGAA TAATGGAAGT TCAGTTTCTA AACAAGCAAA ATCTTGCTCT 
GAGGTCTCTC CCAGTATGTG TCCTGTACAG TCTGTTCCCA CAACAGTGTG TAAGGAGATC 
CTGCTTGGCT GTACTGCAGC AACCCCATCT AGCAAGGGCC CAAGACAGCA GAACACTCCC 
CAGGCAGCCA ATTCTCCACC TAACATTGGA GCAAAACTTC CTCAAGGATG TCACAAGCAG 
AGTTTACCAG AAGAAATTTC TTCCTGTCTA AATACAAAAT CTGAAGTACT GAGAACAAAA 
CCAGATGTTT GCAAAGCAGG ATTACTTTCT TCAAAATCTT CTCAGGTTGG AGCTGGAGAC 
TTGAAAATTC TGAGTGAGCC CAAAGGTAGC TGTATCCAGC CTAAAACAAA CACTGATCAG 
GAGAGCAGAC TGGAGTCTAC TCCACAACCA GTCACTGGCC TTACAAAGGA GTGCTTGGTT 
ACAAAGACTT CCTCTAAGGC AGAACTGGAC AATGCCACTG CTCCTGAACT GCAGAAGCGT 
CTAGAGCACA CAGCTTCCAC ACCCGATGGT CTTTCAGACA AGCCAGAAGT GGAAGCAGGT 
GTCACTAGGC TTAATAGCTG TTCAGAAAAG AAGGTTGGAC CTTCAGATTT AGGTTCGCAG 
TCACAGAATT TAAAGGAAAC TTCAGTAAAA GTCGATCATG ACAGCTGTTG TACAAGAAGC 
AGTAATAAAA CCCAGACTCC CCCAGCCCGG AAGTCAGTTT TGACAGACCC AGATAAACTC 
AAGAAGCTAC AGCAGAGTGG AGAGGCCTTT GTTCAGGATG ACTCCTGTGT TAACATCGTG 
GCACAGCTGC CCAAGTGTCG GGAGTGTCGA TTAGACAGCC TGCGCAAGGA TAAGGACCAG 
CAGAAAGACT CGCCAGTGTT CTGTCGCTTT TTTCACTTCA GGAGGTTACA ATTCAACAAA 
CATGGTGTTC TGCGGGTAGA AGGCTTCTTA ACACCAAACA AGTACGACAG TGAAGCGATT 
GGCTTGTGGC TGCCTTTGAC CAAAAATGTT GTGGGGACTG ATTTGGACAC AGCAAAGTAT 
ATCCTGGCCA ATATTGGAGA CCACTTCTGT CAAATGGTGA TTTCTGAGAA GGAGGCTATG 
TCAACTATTG AGCCACACAG GCAGGTTGCT TGGAAACGAG CTGTCAAAGG AGTTAGAGAA 
ATGTGTGATG TGTGTGACAC AACCATTTTC AACCTGCACT GGGTGTGCCC TCGGTGTGGG 
TTTGGAGTGT GTGTAGATTG CTACCGGATG AAGAGGAAGA ATTGCCAACA GGGGGCTGCC 
TACAAGACTT TCTCTTGGAT AAGGTGTGTG AAGAGTCAAA TACATGAGCC TGAGAACCTG 
ATGCCCACGC AGATTATTCC TGGCAAAGCC CTCTACGATG TTGGAGACAT TGTGCATTCT 
GTCAGAGCAA AATGGGGTAT AAAGGCCAAT TGTCCCTGCT CCAACAGGCA GTTCAAGCTC 
TTCTCGAAGC CAGCCTTAAA GGAAGACCTG AAGCAGGCAT CCTTGTCTGG AGAAAAACCA 
AGTCTCGGCA CCATGGTACA GCAAAGCTCC CCTGTGTTGG AGCCAGCAGC CGTGTGTGGG 
GAAGCACCCT CCAAGCCAGC CAGCAATGTG AAGCCCATCT GTCCAGCCAA CACATCCCCT 
TTAAACTGGC TAGCTGACCT GACCAGTGGC AATGTCAACA AGGAAAACAA GGAAAAACAG 
CTGACTATGC CAATTTTAAA GAACGAAATC AAATGCCTTC CACCCTTGCC TCCTCTGAAC 
AAGTCCAGCA CTGTCCTCCA TACTTTTAAC AGCACAATTT TGACACCCGT GAGCAACAAT 
AATTCTGGTT TTCTTCGAAA TCTTTTGAAT TCATCCACAG GAAAGACAGA AAATGGACTA 
AAAAACACAC CCAAAATCCT TGATGATATC TTTGCCTCTT TGGTACAAAA CAAGACTTCT 
TCTGACTTAT CCAAGAGGCC TCAAGGACTG ACGATCAAGC CTAGCATTCT TGGTTTTGAC 
ACTCCTCACT ACTGGCTGTG TGACAACCGC CTGCTGTGCT TGCAAGACCC CAACAATAAG 
AGCAATTGGA ATGTCTTTAG GGAATGCTGG AAACAGGGGC AGCCAGTGAT GGTGTCGGGA 
GTGCATCATA AATTAAACAC TGAACTCTGG AAACCCGAGT CCTTCAGGAA AGAGTTTGGC 
GAGCAAGAAG TAGACCTAGT CAATTGTAGG ACCAATGAAA TCATCACAGG AGCCACAGTG 
GGAGACTTCT GGGATGGATT TGAAGATGTT CCAAACCGTT TGAAAAACGA AAAAGAAAAA 
GAACCAATGG TGTTGAAACT TAAGGACTGG CCGCCAGGAG AAGACTTTAG AGATATGATG 
CCTTCCAGGT TTGATGATCT GATGGCCAAC ATTCCACTGC CTGAGTATAC CAGGCGAGAT 
GGCAAACTGA ACCTGGCCTC TAGACTGCCA AACTACTTTG TACGGCCAGA CCTGGGCCCC 
AAGATGTACA ATGCTTATGG ATTGATCACT CCAGAAGATC GGAAATATGG GACCACGAAT 
CTTCACTTAG ATGTATCTGA TGCAGCCAAT GTCATGGTTT ATGTGGGAAT TCCCAAAGGA 
CAGTGTGAAC AAGAGGAAGA AGTCCTTAGA ACCATCCAAG ATGGAGATTC GGATGAACTC 
ACAATCAAGC GATTTATTGA AGGAAAAGAG AAGCCAGGCG CCCTTTGGCA CATATATGCT 
GCTAAAGACA CAGAAAAGAT AAGAGAATTC CTTAAAAAGG TATCTGAAGA GCAGGGTCAA 
GAAAACCCCG CAGACCATGA TCCTATTCAT GATCAGAGCT GGTATTTAGA CCGATCACTG 
AGAAAGCGCC TTTATCAAGA GTATGGAGTT CAAGGCTGGG CTATTGTACA ATTTCTTGGC 
GATGTGGTGT TTATCCCGGC AGGAGCTCCA CATCAGGTTC ATAACTTATA CAGCTGTATC 
AAAGTCGCTG AAGACTTCGT GTCTCCAGAG CATGTGAAAC ACTGCTTCTG GCTCACTCAG 
GAATTCCGTC ACTTGTCACA GACTCATACC AACCACGAAG ATAAACTGCA GGTAAAGAAT 
GTTATCTACC ATGCAGTAAA AGATGCAGTT GCTATGCTGA AAGCCAGTGA ATCCAGTTTG 
GGCAAATCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236701.1
CDS	179..4150
Translation	MVLTLGESWPVLVGKRFLSLSAAEGSDGGHDNWDLERVAEWPWLSGTIRAVSHTDVTKKDLKVCVEFDGESWRKRRWIDVYSLLRRAFLVEHNLVLAERKSPEIPEQVIQWPAIMYKSLLDKAGLGSITSVRFLGDQQSVFVSKDLLKPIQDVNSLRLSLTDNQTVSKEFQALIVKHLDESHLLQGDKNLVGSEVRIYSLDPSTQWFSATVVHGNPSSKTLQVNCEEIPALKIVDPALIHVEVVHDNFVTCGNSTRIGAVKRKSSENNGSSVSKQAKSCSEVSPSMCPVQSVPTTVCKEILLGCTAATPSSKGPRQQNTPQAANSPPNIGAKLPQGCHKQSLPEEISSCLNTKSEVLRTKPDVCKAGLLSSKSSQVGAGDLKILSEPKGSCIQPKTNTDQESRLESTPQPVTGLTKECLVTKTSSKAELDNATAPELQKRLEHTASTPDGLSDKPEVEAGVTRLNSCSEKKVGPSDLGSQSQNLKETSVKVDHDSCCTRSSNKTQTPPARKSVLTDPDKLKKLQQSGEAFVQDDSCVNIVAQLPKCRECRLDSLRKDKDQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDSEAIGLWLPLTKNVVGTDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQQGAAYKTFSWIRCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPALKEDLKQASLSGEKPSLGTMVQQSSPVLEPAAVCGEAPSKPASNVKPICPANTSPLNWLADLTSGNVNKENKEKQLTMPILKNEIKCLPPLPPLNKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGLKNTPKILDDIFASLVQNKTSSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNKSNWNVFRECWKQGQPVMVSGVHHKLNTELWKPESFRKEFGEQEVDLVNCRTNEIITGATVGDFWDGFEDVPNRLKNEKEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGKLNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQCEQEEEVLRTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQENPADHDPIHDQSWYLDRSLRKRLYQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRHLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSLGKS

Target ORF information:

RefSeq Version	XM_006236639.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysine demethylase 3A (Kdm3a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236639.2

ORF Insert Sequence:

ATGGTGCTCA CGCTCGGAGA AAGTTGGCCA GTATTGGTGG GGAAGCGATT CCTCAGTCTG 
TCCGCAGCTG AAGGCAGCGA CGGCGGCCAC GACAACTGGG ACTTGGAGCG CGTTGCAGAG 
TGGCCCTGGC TGTCCGGGAC CATTCGAGCT GTTTCTCACA CTGACGTTAC CAAGAAAGAT 
TTGAAGGTTT GTGTGGAGTT TGATGGAGAG TCTTGGAGAA AGAGAAGATG GATAGATGTC 
TACAGCCTTC TAAGAAGAGC ATTTTTAGTA GAACATAACC TGGTTCTGGC AGAACGAAAA 
TCACCTGAGA TTCCTGAGCA AGTTATTCAG TGGCCTGCAA TAATGTACAA ATCTCTACTA 
GACAAAGCTG GCTTGGGATC CATAACTTCT GTTCGCTTCC TTGGAGATCA GCAAAGTGTA 
TTTGTTTCCA AAGACCTTTT GAAACCTATA CAGGATGTAA ACAGTCTTCG GCTTTCCCTT 
ACTGATAATC AGACGGTCAG TAAAGAGTTT CAAGCTTTGA TTGTAAAACA TTTGGATGAA 
AGCCATCTTT TACAAGGTGA CAAGAACCTT GTTGGTTCAG AAGTAAGAAT TTATAGCTTG 
GATCCATCTA CTCAGTGGTT TTCAGCAACT GTTGTACATG GAAACCCCTC ATCCAAAACT 
CTTCAAGTCA ACTGTGAGGA GATTCCAGCG CTGAAAATTG TTGATCCAGC ACTGATTCAC 
GTTGAAGTTG TACACGATAA TTTTGTAACG TGTGGTAATT CTACAAGAAT TGGAGCTGTG 
AAACGCAAGT CTTCTGAGAA TAATGGAAGT TCAGTTTCTA AACAAGCAAA ATCTTGCTCT 
GAGGTCTCTC CCAGTATGTG TCCTGTACAG TCTGTTCCCA CAACAGTGTG TAAGGAGATC 
CTGCTTGGCT GTACTGCAGC AACCCCATCT AGCAAGGGCC CAAGACAGCA GAACACTCCC 
CAGGCAGCCA ATTCTCCACC TAACATTGGA GCAAAACTTC CTCAAGGATG TCACAAGCAG 
AGTTTACCAG AAGAAATTTC TTCCTGTCTA AATACAAAAT CTGAAGTACT GAGAACAAAA 
CCAGATGTTT GCAAAGCAGG ATTACTTTCT TCAAAATCTT CTCAGGTTGG AGCTGGAGAC 
TTGAAAATTC TGAGTGAGCC CAAAGGTAGC TGTATCCAGC CTAAAACAAA CACTGATCAG 
GAGAGCAGAC TGGAGTCTAC TCCACAACCA GTCACTGGCC TTACAAAGGA GTGCTTGGTT 
ACAAAGACTT CCTCTAAGGC AGAACTGGAC AATGCCACTG CTCCTGAACT GCAGAAGCGT 
CTAGAGCACA CAGCTTCCAC ACCCGATGGT CTTTCAGACA AGCCAGAAGT GGAAGCAGGT 
GTCACTAGGC TTAATAGCTG TTCAGAAAAG AAGGTTGGAC CTTCAGATTT AGGTTCGCAG 
TCACAGAATT TAAAGGAAAC TTCAGTAAAA GTCGATCATG ACAGCTGTTG TACAAGAAGC 
AGTAATAAAA CCCAGACTCC CCCAGCCCGG AAGTCAGTTT TGACAGACCC AGATAAACTC 
AAGAAGCTAC AGCAGAGTGG AGAGGCCTTT GTTCAGGATG ACTCCTGTGT TAACATCGTG 
GCACAGCTGC CCAAGTGTCG GGAGTGTCGA TTAGACAGCC TGCGCAAGGA TAAGGACCAG 
CAGAAAGACT CGCCAGTGTT CTGTCGCTTT TTTCACTTCA GGAGGTTACA ATTCAACAAA 
CATGGTGTTC TGCGGGTAGA AGGCTTCTTA ACACCAAACA AGTACGACAG TGAAGCGATT 
GGCTTGTGGC TGCCTTTGAC CAAAAATGTT GTGGGGACTG ATTTGGACAC AGCAAAGTAT 
ATCCTGGCCA ATATTGGAGA CCACTTCTGT CAAATGGTGA TTTCTGAGAA GGAGGCTATG 
TCAACTATTG AGCCACACAG GCAGGTTGCT TGGAAACGAG CTGTCAAAGG AGTTAGAGAA 
ATGTGTGATG TGTGTGACAC AACCATTTTC AACCTGCACT GGGTGTGCCC TCGGTGTGGG 
TTTGGAGTGT GTGTAGATTG CTACCGGATG AAGAGGAAGA ATTGCCAACA GGGGGCTGCC 
TACAAGACTT TCTCTTGGAT AAGGTGTGTG AAGAGTCAAA TACATGAGCC TGAGAACCTG 
ATGCCCACGC AGATTATTCC TGGCAAAGCC CTCTACGATG TTGGAGACAT TGTGCATTCT 
GTCAGAGCAA AATGGGGTAT AAAGGCCAAT TGTCCCTGCT CCAACAGGCA GTTCAAGCTC 
TTCTCGAAGC CAGCCTTAAA GGAAGACCTG AAGCAGGCAT CCTTGTCTGG AGAAAAACCA 
AGTCTCGGCA CCATGGTACA GCAAAGCTCC CCTGTGTTGG AGCCAGCAGC CGTGTGTGGG 
GAAGCACCCT CCAAGCCAGC CAGCAATGTG AAGCCCATCT GTCCAGCCAA CACATCCCCT 
TTAAACTGGC TAGCTGACCT GACCAGTGGC AATGTCAACA AGGAAAACAA GGAAAAACAG 
CTGACTATGC CAATTTTAAA GAACGAAATC AAATGCCTTC CACCCTTGCC TCCTCTGAAC 
AAGTCCAGCA CTGTCCTCCA TACTTTTAAC AGCACAATTT TGACACCCGT GAGCAACAAT 
AATTCTGGTT TTCTTCGAAA TCTTTTGAAT TCATCCACAG GAAAGACAGA AAATGGACTA 
AAAAACACAC CCAAAATCCT TGATGATATC TTTGCCTCTT TGGTACAAAA CAAGACTTCT 
TCTGACTTAT CCAAGAGGCC TCAAGGACTG ACGATCAAGC CTAGCATTCT TGGTTTTGAC 
ACTCCTCACT ACTGGCTGTG TGACAACCGC CTGCTGTGCT TGCAAGACCC CAACAATAAG 
AGCAATTGGA ATGTCTTTAG GGAATGCTGG AAACAGGGGC AGCCAGTGAT GGTGTCGGGA 
GTGCATCATA AATTAAACAC TGAACTCTGG AAACCCGAGT CCTTCAGGAA AGAGTTTGGC 
GAGCAAGAAG TAGACCTAGT CAATTGTAGG ACCAATGAAA TCATCACAGG AGCCACAGTG 
GGAGACTTCT GGGATGGATT TGAAGATGTT CCAAACCGTT TGAAAAACGA AAAAGAAAAA 
GAACCAATGG TGTTGAAACT TAAGGACTGG CCGCCAGGAG AAGACTTTAG AGATATGATG 
CCTTCCAGGT TTGATGATCT GATGGCCAAC ATTCCACTGC CTGAGTATAC CAGGCGAGAT 
GGCAAACTGA ACCTGGCCTC TAGACTGCCA AACTACTTTG TACGGCCAGA CCTGGGCCCC 
AAGATGTACA ATGCTTATGG ATTGATCACT CCAGAAGATC GGAAATATGG GACCACGAAT 
CTTCACTTAG ATGTATCTGA TGCAGCCAAT GTCATGGTTT ATGTGGGAAT TCCCAAAGGA 
CAGTGTGAAC AAGAGGAAGA AGTCCTTAGA ACCATCCAAG ATGGAGATTC GGATGAACTC 
ACAATCAAGC GATTTATTGA AGGAAAAGAG AAGCCAGGCG CCCTTTGGCA CATATATGCT 
GCTAAAGACA CAGAAAAGAT AAGAGAATTC CTTAAAAAGG TATCTGAAGA GCAGGGTCAA 
GAAAACCCCG CAGACCATGA TCCTATTCAT GATCAGAGCT GGTATTTAGA CCGATCACTG 
AGAAAGCGCC TTTATCAAGA GTATGGAGTT CAAGGCTGGG CTATTGTACA ATTTCTTGGC 
GATGTGGTGT TTATCCCGGC AGGAGCTCCA CATCAGGTTC ATAACTTATA CAGCTGTATC 
AAAGTCGCTG AAGACTTCGT GTCTCCAGAG CATGTGAAAC ACTGCTTCTG GCTCACTCAG 
GAATTCCGTC ACTTGTCACA GACTCATACC AACCACGAAG ATAAACTGCA GGTAAAGAAT 
GTTATCTACC ATGCAGTAAA AGATGCAGTT GCTATGCTGA AAGCCAGTGA ATCCAGTTTG 
GGCAAATCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kdm3a ( XM_006236637.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236699.1 Rattus norvegicus lysine demethylase 3A (Kdm3a), transcript variant X1, mRNA.

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CloneID	ORa27332
Clone ID Related Accession (Same CDS sequence)	XM_006236639.2 , XM_006236637.3
Accession Version	XM_006236637.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lysine-specific demethylase 3A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236637.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCTCA CGCTCGGAGA AAGTTGGCCA GTATTGGTGG GGAAGCGATT CCTCAGTCTG 
TCCGCAGCTG AAGGCAGCGA CGGCGGCCAC GACAACTGGG ACTTGGAGCG CGTTGCAGAG 
TGGCCCTGGC TGTCCGGGAC CATTCGAGCT GTTTCTCACA CTGACGTTAC CAAGAAAGAT 
TTGAAGGTTT GTGTGGAGTT TGATGGAGAG TCTTGGAGAA AGAGAAGATG GATAGATGTC 
TACAGCCTTC TAAGAAGAGC ATTTTTAGTA GAACATAACC TGGTTCTGGC AGAACGAAAA 
TCACCTGAGA TTCCTGAGCA AGTTATTCAG TGGCCTGCAA TAATGTACAA ATCTCTACTA 
GACAAAGCTG GCTTGGGATC CATAACTTCT GTTCGCTTCC TTGGAGATCA GCAAAGTGTA 
TTTGTTTCCA AAGACCTTTT GAAACCTATA CAGGATGTAA ACAGTCTTCG GCTTTCCCTT 
ACTGATAATC AGACGGTCAG TAAAGAGTTT CAAGCTTTGA TTGTAAAACA TTTGGATGAA 
AGCCATCTTT TACAAGGTGA CAAGAACCTT GTTGGTTCAG AAGTAAGAAT TTATAGCTTG 
GATCCATCTA CTCAGTGGTT TTCAGCAACT GTTGTACATG GAAACCCCTC ATCCAAAACT 
CTTCAAGTCA ACTGTGAGGA GATTCCAGCG CTGAAAATTG TTGATCCAGC ACTGATTCAC 
GTTGAAGTTG TACACGATAA TTTTGTAACG TGTGGTAATT CTACAAGAAT TGGAGCTGTG 
AAACGCAAGT CTTCTGAGAA TAATGGAAGT TCAGTTTCTA AACAAGCAAA ATCTTGCTCT 
GAGGTCTCTC CCAGTATGTG TCCTGTACAG TCTGTTCCCA CAACAGTGTG TAAGGAGATC 
CTGCTTGGCT GTACTGCAGC AACCCCATCT AGCAAGGGCC CAAGACAGCA GAACACTCCC 
CAGGCAGCCA ATTCTCCACC TAACATTGGA GCAAAACTTC CTCAAGGATG TCACAAGCAG 
AGTTTACCAG AAGAAATTTC TTCCTGTCTA AATACAAAAT CTGAAGTACT GAGAACAAAA 
CCAGATGTTT GCAAAGCAGG ATTACTTTCT TCAAAATCTT CTCAGGTTGG AGCTGGAGAC 
TTGAAAATTC TGAGTGAGCC CAAAGGTAGC TGTATCCAGC CTAAAACAAA CACTGATCAG 
GAGAGCAGAC TGGAGTCTAC TCCACAACCA GTCACTGGCC TTACAAAGGA GTGCTTGGTT 
ACAAAGACTT CCTCTAAGGC AGAACTGGAC AATGCCACTG CTCCTGAACT GCAGAAGCGT 
CTAGAGCACA CAGCTTCCAC ACCCGATGGT CTTTCAGACA AGCCAGAAGT GGAAGCAGGT 
GTCACTAGGC TTAATAGCTG TTCAGAAAAG AAGGTTGGAC CTTCAGATTT AGGTTCGCAG 
TCACAGAATT TAAAGGAAAC TTCAGTAAAA GTCGATCATG ACAGCTGTTG TACAAGAAGC 
AGTAATAAAA CCCAGACTCC CCCAGCCCGG AAGTCAGTTT TGACAGACCC AGATAAACTC 
AAGAAGCTAC AGCAGAGTGG AGAGGCCTTT GTTCAGGATG ACTCCTGTGT TAACATCGTG 
GCACAGCTGC CCAAGTGTCG GGAGTGTCGA TTAGACAGCC TGCGCAAGGA TAAGGACCAG 
CAGAAAGACT CGCCAGTGTT CTGTCGCTTT TTTCACTTCA GGAGGTTACA ATTCAACAAA 
CATGGTGTTC TGCGGGTAGA AGGCTTCTTA ACACCAAACA AGTACGACAG TGAAGCGATT 
GGCTTGTGGC TGCCTTTGAC CAAAAATGTT GTGGGGACTG ATTTGGACAC AGCAAAGTAT 
ATCCTGGCCA ATATTGGAGA CCACTTCTGT CAAATGGTGA TTTCTGAGAA GGAGGCTATG 
TCAACTATTG AGCCACACAG GCAGGTTGCT TGGAAACGAG CTGTCAAAGG AGTTAGAGAA 
ATGTGTGATG TGTGTGACAC AACCATTTTC AACCTGCACT GGGTGTGCCC TCGGTGTGGG 
TTTGGAGTGT GTGTAGATTG CTACCGGATG AAGAGGAAGA ATTGCCAACA GGGGGCTGCC 
TACAAGACTT TCTCTTGGAT AAGGTGTGTG AAGAGTCAAA TACATGAGCC TGAGAACCTG 
ATGCCCACGC AGATTATTCC TGGCAAAGCC CTCTACGATG TTGGAGACAT TGTGCATTCT 
GTCAGAGCAA AATGGGGTAT AAAGGCCAAT TGTCCCTGCT CCAACAGGCA GTTCAAGCTC 
TTCTCGAAGC CAGCCTTAAA GGAAGACCTG AAGCAGGCAT CCTTGTCTGG AGAAAAACCA 
AGTCTCGGCA CCATGGTACA GCAAAGCTCC CCTGTGTTGG AGCCAGCAGC CGTGTGTGGG 
GAAGCACCCT CCAAGCCAGC CAGCAATGTG AAGCCCATCT GTCCAGCCAA CACATCCCCT 
TTAAACTGGC TAGCTGACCT GACCAGTGGC AATGTCAACA AGGAAAACAA GGAAAAACAG 
CTGACTATGC CAATTTTAAA GAACGAAATC AAATGCCTTC CACCCTTGCC TCCTCTGAAC 
AAGTCCAGCA CTGTCCTCCA TACTTTTAAC AGCACAATTT TGACACCCGT GAGCAACAAT 
AATTCTGGTT TTCTTCGAAA TCTTTTGAAT TCATCCACAG GAAAGACAGA AAATGGACTA 
AAAAACACAC CCAAAATCCT TGATGATATC TTTGCCTCTT TGGTACAAAA CAAGACTTCT 
TCTGACTTAT CCAAGAGGCC TCAAGGACTG ACGATCAAGC CTAGCATTCT TGGTTTTGAC 
ACTCCTCACT ACTGGCTGTG TGACAACCGC CTGCTGTGCT TGCAAGACCC CAACAATAAG 
AGCAATTGGA ATGTCTTTAG GGAATGCTGG AAACAGGGGC AGCCAGTGAT GGTGTCGGGA 
GTGCATCATA AATTAAACAC TGAACTCTGG AAACCCGAGT CCTTCAGGAA AGAGTTTGGC 
GAGCAAGAAG TAGACCTAGT CAATTGTAGG ACCAATGAAA TCATCACAGG AGCCACAGTG 
GGAGACTTCT GGGATGGATT TGAAGATGTT CCAAACCGTT TGAAAAACGA AAAAGAAAAA 
GAACCAATGG TGTTGAAACT TAAGGACTGG CCGCCAGGAG AAGACTTTAG AGATATGATG 
CCTTCCAGGT TTGATGATCT GATGGCCAAC ATTCCACTGC CTGAGTATAC CAGGCGAGAT 
GGCAAACTGA ACCTGGCCTC TAGACTGCCA AACTACTTTG TACGGCCAGA CCTGGGCCCC 
AAGATGTACA ATGCTTATGG ATTGATCACT CCAGAAGATC GGAAATATGG GACCACGAAT 
CTTCACTTAG ATGTATCTGA TGCAGCCAAT GTCATGGTTT ATGTGGGAAT TCCCAAAGGA 
CAGTGTGAAC AAGAGGAAGA AGTCCTTAGA ACCATCCAAG ATGGAGATTC GGATGAACTC 
ACAATCAAGC GATTTATTGA AGGAAAAGAG AAGCCAGGCG CCCTTTGGCA CATATATGCT 
GCTAAAGACA CAGAAAAGAT AAGAGAATTC CTTAAAAAGG TATCTGAAGA GCAGGGTCAA 
GAAAACCCCG CAGACCATGA TCCTATTCAT GATCAGAGCT GGTATTTAGA CCGATCACTG 
AGAAAGCGCC TTTATCAAGA GTATGGAGTT CAAGGCTGGG CTATTGTACA ATTTCTTGGC 
GATGTGGTGT TTATCCCGGC AGGAGCTCCA CATCAGGTTC ATAACTTATA CAGCTGTATC 
AAAGTCGCTG AAGACTTCGT GTCTCCAGAG CATGTGAAAC ACTGCTTCTG GCTCACTCAG 
GAATTCCGTC ACTTGTCACA GACTCATACC AACCACGAAG ATAAACTGCA GGTAAAGAAT 
GTTATCTACC ATGCAGTAAA AGATGCAGTT GCTATGCTGA AAGCCAGTGA ATCCAGTTTG 
GGCAAATCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236699.1
CDS	224..4195
Translation	MVLTLGESWPVLVGKRFLSLSAAEGSDGGHDNWDLERVAEWPWLSGTIRAVSHTDVTKKDLKVCVEFDGESWRKRRWIDVYSLLRRAFLVEHNLVLAERKSPEIPEQVIQWPAIMYKSLLDKAGLGSITSVRFLGDQQSVFVSKDLLKPIQDVNSLRLSLTDNQTVSKEFQALIVKHLDESHLLQGDKNLVGSEVRIYSLDPSTQWFSATVVHGNPSSKTLQVNCEEIPALKIVDPALIHVEVVHDNFVTCGNSTRIGAVKRKSSENNGSSVSKQAKSCSEVSPSMCPVQSVPTTVCKEILLGCTAATPSSKGPRQQNTPQAANSPPNIGAKLPQGCHKQSLPEEISSCLNTKSEVLRTKPDVCKAGLLSSKSSQVGAGDLKILSEPKGSCIQPKTNTDQESRLESTPQPVTGLTKECLVTKTSSKAELDNATAPELQKRLEHTASTPDGLSDKPEVEAGVTRLNSCSEKKVGPSDLGSQSQNLKETSVKVDHDSCCTRSSNKTQTPPARKSVLTDPDKLKKLQQSGEAFVQDDSCVNIVAQLPKCRECRLDSLRKDKDQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDSEAIGLWLPLTKNVVGTDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQQGAAYKTFSWIRCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPALKEDLKQASLSGEKPSLGTMVQQSSPVLEPAAVCGEAPSKPASNVKPICPANTSPLNWLADLTSGNVNKENKEKQLTMPILKNEIKCLPPLPPLNKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGLKNTPKILDDIFASLVQNKTSSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNKSNWNVFRECWKQGQPVMVSGVHHKLNTELWKPESFRKEFGEQEVDLVNCRTNEIITGATVGDFWDGFEDVPNRLKNEKEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGKLNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQCEQEEEVLRTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQENPADHDPIHDQSWYLDRSLRKRLYQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRHLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSLGKS

Target ORF information:

RefSeq Version	XM_006236637.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysine demethylase 3A (Kdm3a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236637.3

ORF Insert Sequence:

ATGGTGCTCA CGCTCGGAGA AAGTTGGCCA GTATTGGTGG GGAAGCGATT CCTCAGTCTG 
TCCGCAGCTG AAGGCAGCGA CGGCGGCCAC GACAACTGGG ACTTGGAGCG CGTTGCAGAG 
TGGCCCTGGC TGTCCGGGAC CATTCGAGCT GTTTCTCACA CTGACGTTAC CAAGAAAGAT 
TTGAAGGTTT GTGTGGAGTT TGATGGAGAG TCTTGGAGAA AGAGAAGATG GATAGATGTC 
TACAGCCTTC TAAGAAGAGC ATTTTTAGTA GAACATAACC TGGTTCTGGC AGAACGAAAA 
TCACCTGAGA TTCCTGAGCA AGTTATTCAG TGGCCTGCAA TAATGTACAA ATCTCTACTA 
GACAAAGCTG GCTTGGGATC CATAACTTCT GTTCGCTTCC TTGGAGATCA GCAAAGTGTA 
TTTGTTTCCA AAGACCTTTT GAAACCTATA CAGGATGTAA ACAGTCTTCG GCTTTCCCTT 
ACTGATAATC AGACGGTCAG TAAAGAGTTT CAAGCTTTGA TTGTAAAACA TTTGGATGAA 
AGCCATCTTT TACAAGGTGA CAAGAACCTT GTTGGTTCAG AAGTAAGAAT TTATAGCTTG 
GATCCATCTA CTCAGTGGTT TTCAGCAACT GTTGTACATG GAAACCCCTC ATCCAAAACT 
CTTCAAGTCA ACTGTGAGGA GATTCCAGCG CTGAAAATTG TTGATCCAGC ACTGATTCAC 
GTTGAAGTTG TACACGATAA TTTTGTAACG TGTGGTAATT CTACAAGAAT TGGAGCTGTG 
AAACGCAAGT CTTCTGAGAA TAATGGAAGT TCAGTTTCTA AACAAGCAAA ATCTTGCTCT 
GAGGTCTCTC CCAGTATGTG TCCTGTACAG TCTGTTCCCA CAACAGTGTG TAAGGAGATC 
CTGCTTGGCT GTACTGCAGC AACCCCATCT AGCAAGGGCC CAAGACAGCA GAACACTCCC 
CAGGCAGCCA ATTCTCCACC TAACATTGGA GCAAAACTTC CTCAAGGATG TCACAAGCAG 
AGTTTACCAG AAGAAATTTC TTCCTGTCTA AATACAAAAT CTGAAGTACT GAGAACAAAA 
CCAGATGTTT GCAAAGCAGG ATTACTTTCT TCAAAATCTT CTCAGGTTGG AGCTGGAGAC 
TTGAAAATTC TGAGTGAGCC CAAAGGTAGC TGTATCCAGC CTAAAACAAA CACTGATCAG 
GAGAGCAGAC TGGAGTCTAC TCCACAACCA GTCACTGGCC TTACAAAGGA GTGCTTGGTT 
ACAAAGACTT CCTCTAAGGC AGAACTGGAC AATGCCACTG CTCCTGAACT GCAGAAGCGT 
CTAGAGCACA CAGCTTCCAC ACCCGATGGT CTTTCAGACA AGCCAGAAGT GGAAGCAGGT 
GTCACTAGGC TTAATAGCTG TTCAGAAAAG AAGGTTGGAC CTTCAGATTT AGGTTCGCAG 
TCACAGAATT TAAAGGAAAC TTCAGTAAAA GTCGATCATG ACAGCTGTTG TACAAGAAGC 
AGTAATAAAA CCCAGACTCC CCCAGCCCGG AAGTCAGTTT TGACAGACCC AGATAAACTC 
AAGAAGCTAC AGCAGAGTGG AGAGGCCTTT GTTCAGGATG ACTCCTGTGT TAACATCGTG 
GCACAGCTGC CCAAGTGTCG GGAGTGTCGA TTAGACAGCC TGCGCAAGGA TAAGGACCAG 
CAGAAAGACT CGCCAGTGTT CTGTCGCTTT TTTCACTTCA GGAGGTTACA ATTCAACAAA 
CATGGTGTTC TGCGGGTAGA AGGCTTCTTA ACACCAAACA AGTACGACAG TGAAGCGATT 
GGCTTGTGGC TGCCTTTGAC CAAAAATGTT GTGGGGACTG ATTTGGACAC AGCAAAGTAT 
ATCCTGGCCA ATATTGGAGA CCACTTCTGT CAAATGGTGA TTTCTGAGAA GGAGGCTATG 
TCAACTATTG AGCCACACAG GCAGGTTGCT TGGAAACGAG CTGTCAAAGG AGTTAGAGAA 
ATGTGTGATG TGTGTGACAC AACCATTTTC AACCTGCACT GGGTGTGCCC TCGGTGTGGG 
TTTGGAGTGT GTGTAGATTG CTACCGGATG AAGAGGAAGA ATTGCCAACA GGGGGCTGCC 
TACAAGACTT TCTCTTGGAT AAGGTGTGTG AAGAGTCAAA TACATGAGCC TGAGAACCTG 
ATGCCCACGC AGATTATTCC TGGCAAAGCC CTCTACGATG TTGGAGACAT TGTGCATTCT 
GTCAGAGCAA AATGGGGTAT AAAGGCCAAT TGTCCCTGCT CCAACAGGCA GTTCAAGCTC 
TTCTCGAAGC CAGCCTTAAA GGAAGACCTG AAGCAGGCAT CCTTGTCTGG AGAAAAACCA 
AGTCTCGGCA CCATGGTACA GCAAAGCTCC CCTGTGTTGG AGCCAGCAGC CGTGTGTGGG 
GAAGCACCCT CCAAGCCAGC CAGCAATGTG AAGCCCATCT GTCCAGCCAA CACATCCCCT 
TTAAACTGGC TAGCTGACCT GACCAGTGGC AATGTCAACA AGGAAAACAA GGAAAAACAG 
CTGACTATGC CAATTTTAAA GAACGAAATC AAATGCCTTC CACCCTTGCC TCCTCTGAAC 
AAGTCCAGCA CTGTCCTCCA TACTTTTAAC AGCACAATTT TGACACCCGT GAGCAACAAT 
AATTCTGGTT TTCTTCGAAA TCTTTTGAAT TCATCCACAG GAAAGACAGA AAATGGACTA 
AAAAACACAC CCAAAATCCT TGATGATATC TTTGCCTCTT TGGTACAAAA CAAGACTTCT 
TCTGACTTAT CCAAGAGGCC TCAAGGACTG ACGATCAAGC CTAGCATTCT TGGTTTTGAC 
ACTCCTCACT ACTGGCTGTG TGACAACCGC CTGCTGTGCT TGCAAGACCC CAACAATAAG 
AGCAATTGGA ATGTCTTTAG GGAATGCTGG AAACAGGGGC AGCCAGTGAT GGTGTCGGGA 
GTGCATCATA AATTAAACAC TGAACTCTGG AAACCCGAGT CCTTCAGGAA AGAGTTTGGC 
GAGCAAGAAG TAGACCTAGT CAATTGTAGG ACCAATGAAA TCATCACAGG AGCCACAGTG 
GGAGACTTCT GGGATGGATT TGAAGATGTT CCAAACCGTT TGAAAAACGA AAAAGAAAAA 
GAACCAATGG TGTTGAAACT TAAGGACTGG CCGCCAGGAG AAGACTTTAG AGATATGATG 
CCTTCCAGGT TTGATGATCT GATGGCCAAC ATTCCACTGC CTGAGTATAC CAGGCGAGAT 
GGCAAACTGA ACCTGGCCTC TAGACTGCCA AACTACTTTG TACGGCCAGA CCTGGGCCCC 
AAGATGTACA ATGCTTATGG ATTGATCACT CCAGAAGATC GGAAATATGG GACCACGAAT 
CTTCACTTAG ATGTATCTGA TGCAGCCAAT GTCATGGTTT ATGTGGGAAT TCCCAAAGGA 
CAGTGTGAAC AAGAGGAAGA AGTCCTTAGA ACCATCCAAG ATGGAGATTC GGATGAACTC 
ACAATCAAGC GATTTATTGA AGGAAAAGAG AAGCCAGGCG CCCTTTGGCA CATATATGCT 
GCTAAAGACA CAGAAAAGAT AAGAGAATTC CTTAAAAAGG TATCTGAAGA GCAGGGTCAA 
GAAAACCCCG CAGACCATGA TCCTATTCAT GATCAGAGCT GGTATTTAGA CCGATCACTG 
AGAAAGCGCC TTTATCAAGA GTATGGAGTT CAAGGCTGGG CTATTGTACA ATTTCTTGGC 
GATGTGGTGT TTATCCCGGC AGGAGCTCCA CATCAGGTTC ATAACTTATA CAGCTGTATC 
AAAGTCGCTG AAGACTTCGT GTCTCCAGAG CATGTGAAAC ACTGCTTCTG GCTCACTCAG 
GAATTCCGTC ACTTGTCACA GACTCATACC AACCACGAAG ATAAACTGCA GGTAAAGAAT 
GTTATCTACC ATGCAGTAAA AGATGCAGTT GCTATGCTGA AAGCCAGTGA ATCCAGTTTG 
GGCAAATCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

KDM3A inhibition attenuates high concentration insulin?induced vascular smooth muscle cell injury by suppressing MAPK/NF??B pathways.
International journal of molecular medicine41(3)1265-1274(2018 Mar)
Zhang BF,Jiang H,Chen J,Guo X,Hu Q,Yang S

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.
Cell chemical biology24(3)371-380(2017 Mar)
Tumber A,Nuzzi A,Hookway ES,Hatch SB,Velupillai S,Johansson C,Kawamura A,Savitsky P,Yapp C,Szykowska A,Wu N,Bountra C,Strain-Damerell C,Burgess-Brown NA,Ruda GF,Fedorov O,Munro S,England KS,Nowak RP,Schofield CJ,La Thangue NB,Pawlyn C,Davies F,Morgan G,Athanasou N,M?ller S,Oppermann U,Brennan PE

Histone demethylase KDM3a, a novel regulator of vascular smooth muscle cells, controls vascular neointimal hyperplasia in diabetic rats.
Atherosclerosis257152-163(2017 Feb)
Chen J,Zhang J,Yang J,Xu L,Hu Q,Xu C,Yang S,Jiang H

HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia.
Proceedings of the National Academy of Sciences of the United States of America113(46)E7212-E7221(2016 Nov)
Chakraborty D,Cui W,Rosario GX,Scott RL,Dhakal P,Renaud SJ,Tachibana M,Rumi MA,Mason CW,Krieg AJ,Soares MJ

The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma.
Oncogene34(2)257-62(2015 Jan)
Parrish JK,Sechler M,Winn RA,Jedlicka P

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Kdm3a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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